C. Roy

The Coxiella burnetii effector EmcB is a deubiquitinase that inhibits RIG-I signaling
202313 citationsauthor #5
Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection
20237 citationsauthor #6
Developmental Transitions Coordinate Assembly of the Coxiella burnetii Dot/Icm Type IV Secretion System
202217 citationsauthor #4
Cover Image: Coxiella burnetii encodes an LvgA-related protein important for intracellular replication (Cellular Microbiology 06/2021)
20210 citationsauthor #3
The Legionella pneumophila Effector RavY Contributes to a Replication-Permissive Vacuolar Environment during Infection
20213 citationsauthor #2
Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila
20219 citationsauthor #7
Coxiella burnetii encodes an LvgA‐related protein important for intracellular replication
20219 citationsauthor #3
IFNγ-induced mechanisms restrict intracellular replication of the lysosome-adapted bacterial pathogen, Coxiella burnetii
20200 citationsauthor #5
Applying Live Cell Imaging and Cryo-Electron Tomography to Resolve Spatiotemporal Features of the Legionella pneumophila Dot/Icm Secretion System.
20203 citationsauthor #5
Analysis of Dot/Icm Type IVB Secretion System Subassemblies by Cryoelectron Tomography Reveals Conformational Changes Induced by DotB Binding
202040 citationsauthor #4
Mechanism of effector capture and delivery by the type IV secretion system from Legionella pneumophila
202055 citationsauthor #7
Legionella pneumophila Excludes Autophagy Adaptors from the Ubiquitin-Labeled Vacuole in Which It Resides
202033 citationsauthor #2
Lysosomal degradation products induce Coxiella burnetii virulence
202037 citationsauthor #11
Manipulation of Host Cell Organelles by Intracellular Pathogens
201963 citationsauthor #2
Host cell depletion of tryptophan by IFNγ-induced Indoleamine 2,3-dioxygenase 1 (IDO1) inhibits lysosomal replication of Coxiella burnetii
201928 citationsauthor #2
Screening Legionella effectors for antiviral effects reveals Rab1 GTPase as a proviral factor coopted for tombusvirus replication
201926 citationsauthor #5
Biogenesis of the Spacious Coxiella-Containing Vacuole Depends on Host Transcription Factors TFEB and TFE3
201919 citationsauthor #9
Legionella DotM structure reveals a role in effector recruiting to the Type 4B secretion system
201842 citationsauthor #4
Role of conjugative relaxases in DNA transfer and integration. Development of biotechnological tools
20180 citationsauthor #5
Dot/Icm-Translocated Proteins Important for Biogenesis of the Coxiella burnetii-Containing Vacuole Identified by Screening of an Effector Mutant Sublibrary
201842 citationsauthor #5
A Unique Cytoplasmic ATPase Complex Defines the Legionella pneumophila Type IV Secretion Channel
201885 citationsauthor #4
Legionella remodels the plasma membrane–derived vacuole by utilizing exocyst components as tethers
201822 citationsauthor #4
Acyl Histidines: New N‐Acyl Amides from Legionella pneumophila
201714 citationsauthor #4
Autophagic targeting and avoidance in intracellular bacterial infections.
201723 citationsauthor #2
A Farnesylated Coxiella burnetii Effector Forms a Multimeric Complex at the Mitochondrial Outer Membrane during Infection
201726 citationsauthor #6
Multiple Legionella pneumophila effector virulence phenotypes revealed through high-throughput analysis of targeted mutant libraries
201787 citationsauthor #6
DNA Delivery and Genomic Integration into Mammalian Target Cells through Type IV A and B Secretion Systems of Human Pathogens
201727 citationsauthor #5
DNA transfer and genomic integration in human cells using Type IV Secretion Systems of human pathogens
20170 citationsauthor #5
Subversion of Host Membrane Dynamics by the Legionella Dot/Icm Type IV Secretion System.
201718 citationsauthor #4
Primary Role for Toll-Like Receptor-Driven Tumor Necrosis Factor Rather than Cytosolic Immune Detection in Restricting Coxiella burnetii Phase II Replication within Mouse Macrophages
201631 citationsauthor #9
Legionella pneumophila Type IV Effectors YlfA and YlfB Are SNARE-Like Proteins that Form Homo- and Heteromeric Complexes and Enhance the Efficiency of Vacuole Remodeling
201611 citationsauthor #2
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1 (cid:2) and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia
20160 citationsauthor #9
Chitinase 3-Like 1 (Chil1) Regulates Survival and Macrophage-Mediated Interleukin-1β and Tumor Necrosis Factor Alpha during Pseudomonas aeruginosa Pneumonia
201620 citationsauthor #9
MTOR-Driven Metabolic Reprogramming Regulates Legionella pneumophila Intracellular Niche Homeostasis
201624 citationsauthor #3
Erratum for Kohler et al., Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole
20165 citationsauthor #6
Autophagy Evasion and Endoplasmic Reticulum Subversion: The Yin and Yang of Legionella Intracellular Infection.
201672 citationsauthor #2
Chil 1 ) Regulates Survival and Macrophage-mediated IL-1 β and TNF-α 1 during Pseudomonas Pneumonia 2 3 Running Title : Chil 1 and Inflammation in Pseudomonas Infection 4 5
20160 citationsauthor #9
Effector Protein Cig2 Decreases Host Tolerance of Infection by Directing Constitutive Fusion of Autophagosomes with the Coxiella-Containing Vacuole
201662 citationsauthor #6
Structure and function of Fic proteins
201549 citationsauthor #1
The Legionella Anti-autophagy Effector RavZ Targets the Autophagosome via PI3P- and Curvature-Sensing Motifs.
201592 citationsauthor #7
Biogenesis of the lysosome-derived vacuole containing Coxiella burnetii.
201551 citationsauthor #2
234 – Legionnaires' Disease and Pontiac Fever
20158 citationsauthor #2
On the use of Legionella/Rickettsia chimeras to investigate the structure and regulation of Rickettsia effector RalF.
20157 citationsauthor #4
Inhibition of inflammasome activation by Coxiella burnetii type IV secretion system effector IcaA
201586 citationsauthor #8
Contributors
20150 citationsauthor #349
Association of specific Coxiella burnetii genotypes with animal reservoirs and human disease
20150 citationsauthor #20
Crystal structure of a chimeric protein with the Sec7 domain of Legionella pneumophila RalF and the capping domain of Rickettsia prowazekii RalF
20150 citationsauthor #4
Toxicity and SidJ-Mediated Suppression of Toxicity Require Distinct Regions in the SidE Family of Legionella pneumophila Effectors
201548 citationsauthor #2
The Genus Legionella
20151 citationsauthor #3
Crystal structure of a chimeric protein with the Sec7 domain of Rickettsia prowazekii RalF and the capping domain of Legionella pneumophila RalF
20150 citationsauthor #4
Structure and mechanism of bacterial effectors that hijack trafficking small GTPases (LB278)
20140 citationsauthor #3
The Machinery at Endoplasmic Reticulum-Plasma Membrane Contact Sites Contributes to Spatial Regulation of Multiple Legionella Effector Proteins
201467 citationsauthor #8
Autophagy is required for homotypic fusion of CCVs.
20140 citationsauthor #7
Inhibition of non-canonical activation of the inflammasome by a novel type IV secretion system substrate of the intracellular bacteria Coxiella burnetti
20140 citationsauthor #5
Structural basis for PI(4)P-specific membrane recruitment of the Legionella pneumophila effector DrrA/SidM.
201454 citationsauthor #4
Keller Cancer Cell Survival in Glucose-Limited Conditions SAICAR Stimulates Pyruvate Kinase Isoform M 2 and Promotes
20140 citationsauthor #8
Alveolar Macrophages and Neutrophils Are the Primary Reservoirs for Legionella pneumophila and Mediate Cytosolic Surveillance of Type IV Secretion
201479 citationsauthor #6
Legionella pneumophila Subversion of Host Vesicular Transport by SidC Effector Proteins
201472 citationsauthor #6
Complementary immune roles for infected and uninfected cells during bacterial infection (INC7P.425)
20140 citationsauthor #6
Crystal structure of an N-terminal fragment of the Legionella pneumophila effector protein SidC.
20140 citationsauthor #6
A Screen of Coxiella burnetii Mutants Reveals Important Roles for Dot/Icm Effectors and Host Autophagy in Vacuole Biogenesis
2014165 citationsauthor #7
AMPylation Is Critical for Rab1 Localization to Vacuoles Containing Legionella pneumophila
201459 citationsauthor #2
MyD88-Dependent Production of Legionella Inhibit T Cells by Means of Activated Macrophages Infected with
20130 citationsauthor #3
Autophagy and bacterial infection: an evolving arms race.
201353 citationsauthor #2
Analyzing caspase-1 activation during Legionella pneumophila infection in macrophages.
201317 citationsauthor #2
A Rab-centric perspective of bacterial pathogen-occupied vacuoles.
2013101 citationsauthor #2
Crystal Structure of lepB GAP core in a transition state mimetic complex with Rab1A and ALF3
20130 citationsauthor #4
Inflammasome activation restricts Legionella pneumophila replication in primary microglial cells through flagellin detection
201345 citationsauthor #10
The Legionella pneumophila GTPase Activating Protein LepB Accelerates Rab1 Deactivation by a Non-canonical Hydrolytic Mechanism*
201335 citationsauthor #4
Pathogen signatures activate a ubiquitinylation pathway that modulates function of the metabolic checkpoint kinase mTOR
2013108 citationsauthor #2
Host Pathways Important for Coxiella burnetii Infection Revealed by Genome-Wide RNA Interference Screening
2013116 citationsauthor #6
A Novel Membrane Sensor Controls the Localization and ArfGEF Activity of Bacterial RalF
201334 citationsauthor #10
Host lipidation: a mechanism for spatial regulation of Legionella effectors.
201321 citationsauthor #2
Structure of the Legionella effector AnkX, an enzyme that diverts the small GTPase Rab1
20131 citationsauthor #3
Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain
201375 citationsauthor #3
Evasion of Phagosome Lysosome Fusion and Establishment of a Replicative Organelle by the Intracellular Pathogen Legionella pneumophila
20135 citationsauthor #1
HowLegionelladiverts host small GTPases: structural and biochemical studies
20132 citationsauthor #4
Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein in complex with cytidine monophosphate and phosphocholine
20131 citationsauthor #3
Crystal structure of Legionella pneumophila RalF F255K mutant
20130 citationsauthor #10
Identification and functional characterization of K+ transporters encoded by Legionella pneumophila kup genes
20135 citationsauthor #3
Caspase-11 stimulates rapid flagellin-independent pyroptosis in response to Legionella pneumophila
2013278 citationsauthor #8
Crystal structure of the Legionella pneumophila FIC domain-containing effector AnkX protein (inactive H229A mutant) in complex with cytidine-diphosphate-choline
20130 citationsauthor #3
Meeting report – Arf and Rab family G proteins
20134 citationsauthor #5
Effector Protein Translocation by the Coxiella burnetii Dot/Icm Type IV Secretion System Requires Endocytic Maturation of the Pathogen-Occupied Vacuole
2013128 citationsauthor #3
The role of Rab GTPases in the transport of vacuoles containing Legionella pneumophila and Coxiella burnetii.
201225 citationsauthor #4
The Legionella pneumophila effector DrrA is sufficient to stimulate SNARE-dependent membrane fusion.
201299 citationsauthor #3
The Capping Domain in RalF Regulates Effector Functions
201239 citationsauthor #9
Coxiella burnetii secretion systems.
201214 citationsauthor #3
Vacuolar pathogens value membrane integrity
20128 citationsauthor #1
The Legionella Effector RavZ Inhibits Host Autophagy Through Irreversible Atg8 Deconjugation
2012441 citationsauthor #7
Dissection of a type I interferon pathway in controlling bacterial intracellular infection in mice
2011100 citationsauthor #13
Asc Modulates the Function of NLRC4 in Response to Infection of Macrophages by Legionella pneumophila
201187 citationsauthor #2
The Coxiella burnetii Dot/Icm System Creates a Comfortable Home through Lysosomal Renovation
201135 citationsauthor #2
Subversion of membrane transport pathways by vacuolar pathogens
201197 citationsauthor #3
Modulation of Rab GTPase function by a protein phosphocholine transferase
2011308 citationsauthor #6
The Coxiella burnetii Dot/Icm System Delivers a Unique Repertoire of Type IV Effectors into Host Cells and Is Required for Intracellular Replication
2011231 citationsauthor #4
Dual Chaperone Role of the C-Terminal Propeptide in Folding and Oligomerization of the Pore-Forming Toxin Aerolysin
201168 citationsauthor #8
Modulation of host cell function by Legionella pneumophila type IV effectors.
2010456 citationsauthor #2
The Anaplasma phagocytophilum‐occupied vacuole selectively recruits Rab‐GTPases that are predominantly associated with recycling endosomes
201074 citationsauthor #4
Lipidation by the Host Prenyltransferase Machinery Facilitates Membrane Localization of Legionella pneumophila Effector Proteins*
2010106 citationsauthor #4

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