R. Kember

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Aliases
R. L. Kember, Rachel L. Kember, Rachel Kember, R.l. Kember, Rachel L Kember
Publication record
132 papers · 5,140 citations · H-index 31

PAPERS

Environmental, Psychiatric, and Genetic Predictors of Alcohol Use Disorder Criterion Count: Analyses of African and European Ancestries.
20252 citationsauthor #4
Transdiagnostic and Disorder-Level GWAS Enhance Precision of Substance Use and Psychiatric Genetic Risk Profiles in African and European Ancestries.
20253 citationsauthor #11
Racial and ethnic disparities in buprenorphine retention and treatment outcome in a longitudinal cohort of U.S. veterans with opioid use disorder.
20250 citationsauthor #3
Integrating HiTOP and RDoC frameworks part II: shared and distinct biological mechanisms of externalizing and internalizing psychopathology
20252 citationsauthor #8
Moderation of treatment outcomes by polygenic risk for alcohol‐related traits in placebo‐controlled trials of topiramate
20251 citationsauthor #7
Utility of Candidate Genes From an Algorithm Designed to Predict Genetic Risk for Opioid Use Disorder
20254 citationsauthor #14
Predicting treatment-seeking status for alcohol use disorder using polygenic scores and machine learning in a deeply-phenotyped sample.
20250 citationsauthor #5
Demographic and Genetic Predictors of ADHD Diagnoses and Medications in Electronic Health Records
20250 citationsauthor #4
Multi-ancestry genome-wide association meta-analysis of buprenorphine treatment response
20251 citationsauthor #8
Gene discovery and pleiotropic architecture of chronic pain in a genome-wide association study of >1.2 million individuals
20253 citationsauthor #8
Sex-Specific Genetic Architecture and Comorbidities of Alcohol Use Behaviors
20251 citationsauthor #23
Cross-ancestry and phenome-wide associations of cancer-specific polygenic risk scores
20250 citationsauthor #10
Polygenic prediction of body mass index and obesity through the life course and across ancestries
202514 citationsauthor #133
Major Depressive Disorder Impacts Peripheral Artery Disease Risk Through Intermediary Risk Factors
20245 citationsauthor #5
14. A Multi-PGS Approach to Predicting Substance Use Disorders Diagnoses in the EHR
20240 citationsauthor #9
Author Correction: A multi-ancestry genetic study of pain intensity in 598,339 veterans
20241 citationsauthor #18
Genetic contribution to the comorbidity between attention-deficit/hyperactivity disorder and substance use disorders.
202411 citationsauthor #14
Combining Transdiagnostic and Disorder-Level GWAS Enhances Precision of Psychiatric Genetic Risk Profiles in a Multi-Ancestry Sample
20245 citationsauthor #11
Author Correction: Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
20242 citationsauthor #16
A multi-ancestry genetic study of pain intensity in 598,339 veterans
202432 citationsauthor #18
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and medical traits
20240 citationsauthor #7
Multivariate, Multi-omic Analysis in 799,429 Individuals Identifies 134 Loci Associated with Somatoform Traits
20243 citationsauthor #10
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens
20246 citationsauthor #8
Divergent gene expression patterns in alcohol and opioid use disorders lead to consistent alterations in functional networks within the Dorsolateral Prefrontal Cortex
20245 citationsauthor #5
Application of polygenic scores to a deeply phenotyped sample enriched for substance use disorders reveals extensive pleiotropy with psychiatric and somatic traits
20246 citationsauthor #7
Predicting Treatment-Seeking Status for Alcohol Use Disorder Using Polygenic Scores and Machine Learning in a Deeply-Phenotyped Sample
20240 citationsauthor #5
Candidate Genes from an FDA-Approved Algorithm Fail to Predict Opioid Use Disorder Risk in Over 450,000 Veterans
20242 citationsauthor #14
A Mendelian randomization study of alcohol use and cardiometabolic disease risk in a multi‐ancestry population from the Million Veteran Program
20244 citationsauthor #1
Mo1420 THE IMPACT OF PHENOTYPIC HETEROGENEITY ON GENOME WIDE ASSOCIATION STUDIES OF PANCREATIC DUCTAL ADENOCARCINOMA
20240 citationsauthor #8
Multi-omic network analysis identifies dysregulated neurobiological pathways in opioid addiction
20245 citationsauthor #20
Concerns about genetic risk testing for opioid use disorder.
20242 citationsauthor #3
Identifying neurofunctional domains across substance use disorders
20240 citationsauthor #5
Gene × environment effects and mediation involving adverse childhood events, mood and anxiety disorders, and substance dependence
20247 citationsauthor #16
High dimensional predictions of suicide risk in 4.2 million US Veterans using ensemble transfer learning
202413 citationsauthor #55
A single-nucleus transcriptomic atlas of medium spiny neurons in the rat nucleus accumbens
20241 citationsauthor #8
Author Correction: Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes
20240 citationsauthor #2
Multi-ancestry meta-analysis of tobacco use disorder identifies 461 potential risk genes and reveals associations with multiple health outcomes
202436 citationsauthor #33
Trans-ancestral genome-wide association study of longitudinal pubertal height growth and shared heritability with adult health outcomes
202411 citationsauthor #2
Polygenic risk scores for cardiometabolic traits demonstrate importance of ancestry for predictive precision medicine
20246 citationsauthor #1
Considerations for the application of polygenic scores to clinical care of individuals with substance use disorders
20245 citationsauthor #1
Pleiotropy and genetically inferred causality linking multisite chronic pain to substance use disorders
20248 citationsauthor #10
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program
2024222 citationsauthor #37
A Multivariate Genome-Wide Association Study Reveals Neural Correlates and Common Biological Mechanisms of Psychopathology Spectra
20245 citationsauthor #8
Germline Exome Sequencing for Men with Testicular Germ Cell Tumor Reveals Coding Defects in Chromosomal Segregation and Protein-targeting Genes.
202312 citationsauthor #10
The genetic architecture of pain intensity in a sample of 598,339 U.S. veterans
20238 citationsauthor #18
Multi-ancestry study of the genetics of problematic alcohol use in >1 million individuals
202319 citationsauthor #2
Multi-ancestry meta-analysis of tobacco use disorder prioritizes novel candidate risk genes and reveals associations with numerous health outcomes
20236 citationsauthor #33
Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene X Environment Effects and Moderated Mediation
20231 citationsauthor #16
Diversity and Scale: Genetic Architecture of 2,068 Traits in the VA Million Veteran Program
202324 citationsauthor #37
Polygenic risk scores for cardiometabolic traits demonstrate importance of ancestry for predictive precision medicine.
20230 citationsauthor #1
The Relationship between Alcohol- and Sleep-related Traits: Results from Polygenic Risk Score Analyses and Mendelian Randomization Studies
20232 citationsauthor #2
Identifying Genetic Loci and Phenomic Associations of Substance Use Traits: A Multi-trait Analysis of GWAS (MTAG) study.
202316 citationsauthor #11
Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals
2023109 citationsauthor #2
Author Correction: The power of genetic diversity in genome-wide association studies of lipids
20238 citationsauthor #128
Racial and Ethnic Bias in the Diagnosis of Alcohol Use Disorder in Veterans.
202330 citationsauthor #9
Does Polygenic Risk for Substance-Related Traits Predict Ages of Onset and Progression of Symptoms?
202311 citationsauthor #11
The relationship between alcohol- and sleep-related traits: Results from polygenic risk score and Mendelian randomization analyses.
202310 citationsauthor #2
Multi-trait genome-wide association analyses leveraging alcohol use disorder findings identify novel loci for smoking behaviors in the Million Veteran Program
20225 citationsauthor #5
Session Introduction: SALUD: Scalable Applications of cLinical risk Utility and preDiction.
20220 citationsauthor #7
A saturated map of common genetic variants associated with human height
2022581 citationsauthor #137
Multi-trait Analysis of GWAS (MTAG) of Substance Use Traits Identifies Novel Genetic Loci and Phenomic Associations
20221 citationsauthor #9
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
2022260 citationsauthor #59
A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation
2022151 citationsauthor #22
Genome-wide significant risk loci for mood disorders in the Old Order Amish founder population
20227 citationsauthor #3
The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population
2022107 citationsauthor #8
Unique and joint associations of polygenic risk for major depression and opioid use disorder with endogenous opioid system function
20223 citationsauthor #3
Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci
202293 citationsauthor #14
Polygenic Risk for Substance-Related Traits Predicts Substance Use Onset and Progression: Sex and Population Group Differences
20221 citationsauthor #11
Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits
202216 citationsauthor #4
High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease
202242 citationsauthor #10
Is anxiety a pathway to Alcohol Use Disorders? A phenome-wide association study of the GABRA2 coding variant rs279858
20222 citationsauthor #2
Substance use and common contributors to morbidity: A genetics perspective
202218 citationsauthor #2
Identifying and Reducing Bias in Genome-Wide Association Studies of Alcohol-Related Traits.
20225 citationsauthor #3
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
202258 citationsauthor #51
Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.
202243 citationsauthor #53
Phenome-wide association analysis of substance use disorders in a deeply phenotyped sample
202244 citationsauthor #1
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
20226 citationsauthor #48
Identifying High-Risk Comorbidities Associated with Opioid Use Patterns Using Electronic Health Record Prescription Data
202212 citationsauthor #9
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects in brain regions associated with addiction
202273 citationsauthor #1
Abstract 361: Bidirectional Mendelian Randomization Investigating The Causal Relationship Between Major Depressive Disorder And Peripheral Artery Disease
20221 citationsauthor #5
A large-scale multi-ethnic genome-wide association study of coronary artery disease
202110 citationsauthor #53
Performance of polygenic risk scores for cancer prediction in a racially diverse academic biobank
202121 citationsauthor #14
A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation
20213 citationsauthor #25
Genetic underpinnings of the transition from alcohol consumption to alcohol use disorder: shared and unique genetic architectures in a cross-ancestry sample
202139 citationsauthor #1
The power of genetic diversity in genome-wide association studies of lipids
2021693 citationsauthor #128
Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction
2021255 citationsauthor #16
Identifying high-risk comorbidities of short and long-term opioid prescription use
20212 citationsauthor #9
Association of Inherited Mutations in DNA Repair Genes with Localized Prostate Cancer
202131 citationsauthor #15
Racial Inequalities in Alcohol Use Disorder Diagnosis in a Sample of 700,000 Veterans
20211 citationsauthor #9
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain
202111 citationsauthor #1
Genome-wide association study and multi-trait analysis of opioid use disorder identifies novel associations in 639,709 individuals of European and African ancestry.
20218 citationsauthor #14
Cross-ancestry meta-analysis of opioid use disorder uncovers novel loci with predominant effects on brain
20210 citationsauthor #1
The Impact of Removing Former Drinkers from Genome-wide Association Studies of AUDIT-C.
202116 citationsauthor #6
Kidney disease genetic risk variants alter lysosomal beta-mannosidase (MANBA) expression and disease severity
202146 citationsauthor #8
Investigation of convergent and divergent genetic influences underlying schizophrenia and alcohol use disorder
20219 citationsauthor #9
Exome-wide evaluation of rare coding variants using electronic health records identifies new gene–phenotype associations
202151 citationsauthor #24
Genetic liability for substance use associated with medical comorbidities in electronic health records of African‐ and European‐ancestry individuals
202115 citationsauthor #6
Abstract LB222: Performance of polygenic risk scores for GI cancer prediction in an academic biobank
20210 citationsauthor #13
Analysis of genetic and clinical factors associated with buprenorphine response.
202111 citationsauthor #3
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
2020316 citationsauthor #9

TIMELINE

2018 23 citations

2019 953 citations

2020 740 citations

2021 1,222 citations

2022 1,529 citations

2023 256 citations

2024 403 citations

2025 31 citations

Unknown 0 citations

R. Kember

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