T. Lefebvre

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T Lefebvre, Tony Lefebvre
Publication record
80 papers · 3,320 citations · H-index 35

PAPERS

O-GlcNAc Dynamics: The Sweet Side of Protein Trafficking Regulation in Mammalian Cells
202315 citationsauthor #5
Involvement of the pro-oncogenic enzyme fatty acid synthase in the hallmarks of cancer: a promising target in anti-cancer therapies
202374 citationsauthor #3
Control of lipid metabolism by the dynamic and nutrient‐dependent post‐translational modification O ‐GlcNAcylation
20233 citationsauthor #11
Follicular cells protect Xenopus oocyte from abnormal maturation via integrin signaling downregulation and O-GlcNAcylation control
20234 citationsauthor #8
Switching azide and alkyne tags on bioorthogonal reporters in metabolic labeling of sialylated glycoconjugates: a comparative study
202212 citationsauthor #5
Evaluation of the expression of fatty acid synthase and O-GlcNAc transferase in patients with liver cancer by exploration of transcriptome databases and experimental approaches
20226 citationsauthor #7
Dual regulation of fatty acid synthase (FASN) expression by O-GlcNAc transferase (OGT) and mTOR pathway in proliferating liver cancer cells
202143 citationsauthor #14
Mitochondrial O-GlcNAc Transferase Interacts with and Modifies Many Proteins and Its Up-Regulation Affects Mitochondrial Function and Cellular Energy Homeostasis
202124 citationsauthor #11
AABC_A_294867 87..102
20210 citationsauthor #2
Thymidylate synthase O-GlcNAcylation: a molecular mechanism of 5-FU sensitization in colorectal cancer
202123 citationsauthor #10
O-GlcNAcylation Prediction: An Unattained Objective
202111 citationsauthor #4
Exploring the Potential of β-Catenin O-GlcNAcylation by Using Fluorescence-Based Engineering and Imaging
202011 citationsauthor #7
Identification of lipid raft glycoproteins obtained from boar spermatozoa
20206 citationsauthor #5
Cyclin D1 Stability Is Partly Controlled by O-GlcNAcylation
201928 citationsauthor #6
Editorial: O-GlcNAcylation: Expanding the Frontiers
20193 citationsauthor #2
OGT Controls the Expression and the Glycosylation of E‐cadherin, and Affects Glycosphingolipid Structures in Human Colon Cell Lines
201912 citationsauthor #11
Identification of O-Glcnacylated Proteins in Trypanosoma cruzi
20199 citationsauthor #6
O-GlcNAcylation Is Involved in the Regulation of Stem Cell Markers Expression in Colon Cancer Cells
201916 citationsauthor #4
Combinatorial regulation of hepatic cytoplasmic signaling and nuclear transcriptional events by the OGT/REV-ERBα complex
201849 citationsauthor #18
The Many Ways by Which O-GlcNAcylation May Orchestrate the Diversity of Complex Glycosylations
201839 citationsauthor #5
Apart From Rhoptries, Identification of Toxoplasma gondii's O-GlcNAcylated Proteins Reinforces the Universality of the O-GlcNAcome
201810 citationsauthor #16
Cross regulation between mTOR signaling and O-GlcNAcylation
201844 citationsauthor #6
O-GlcNAc transferase associates with the MCM2–7 complex and its silencing destabilizes MCM–MCM interactions
201821 citationsauthor #5
Disrupting membrane lipids composition promotes tumorigenesis: the other dark side of cholesterol and the potential implication of gangliosides
20182 citationsauthor #1
Cross-Dysregulation of O-GlcNAcylation and PI3K/AKT/mTOR Axis in Human Chronic Diseases
201883 citationsauthor #3
OGT: a short overview of an enzyme standing out from usual glycosyltransferases.
201735 citationsauthor #5
The RBM14/CoAA-interacting, long intergenic non-coding RNA Paral1 regulates adipogenesis and coactivates the nuclear receptor PPARγ
201736 citationsauthor #15
O-GlcNAcylation and chromatin remodeling in mammals: an up-to-date overview.
201736 citationsauthor #2
Effect of amyloid-Β (25-35) in hyperglycemic and hyperinsulinemic rats, effects on phosphorylation and O-GlcNAcylation of tau protein.
20179 citationsauthor #3
Recombinant fungal lectin as a new tool to investigate O-GlcNAcylation processes
201720 citationsauthor #6
Identification of O-GlcNAcylated proteins in Plasmodium falciparum
201726 citationsauthor #8
Drug resistance related to aberrant glycosylation in colorectal cancer
201791 citationsauthor #2
The Nutrient-Dependent O-GlcNAc Modification Controls the Expression of Liver Fatty Acid Synthase.
201657 citationsauthor #5
O-GlcNAcylation: A sweet thorn in the spindle!
20164 citationsauthor #1
Silencing the Nucleocytoplasmic O-GlcNAc Transferase Reduces Proliferation, Adhesion, and Migration of Cancer and Fetal Human Colon Cell Lines
201644 citationsauthor #8
O-GlcNAcylation and the Metabolic Shift in High-Proliferating Cells: All the Evidence Suggests that Sugars Dictate the Flux of Lipid Biogenesis in Tumor Processes
201622 citationsauthor #2
Glucokinase expression is regulated by glucose through O-GlcNAc glycosylation.
201633 citationsauthor #6
Evidence for an imbalance between tau O-GlcNAcylation and phosphorylation in the hippocampus of a mouse model of Alzheimer's disease.
201652 citationsauthor #2
Detection and identification of O‐GlcNAcylated proteins by proteomic approaches
201531 citationsauthor #11
Modification by SUMOylation Controls Both the Transcriptional Activity and the Stability of Delta-Lactoferrin
201521 citationsauthor #7
Regulatory O-GlcNAcylation sites on FoxO1 are yet to be identified.
201529 citationsauthor #5
30 Years Old: O-GlcNAc Reaches the Age of Reason – Regulation of Cell Signaling and Metabolism by O-GlcNAcylation
201514 citationsauthor #1
Cryptosporidium parvum-induced ileo-caecal adenocarcinoma and Wnt signaling in a mouse model
201447 citationsauthor #17
Glucose sensing O‐GlcNAcylation pathway regulates the nuclear bile acid receptor farnesoid X receptor (FXR)
201466 citationsauthor #12
O‐GlcNAcylation stabilizes β‐catenin through direct competition with phosphorylation at threonine 41
2014133 citationsauthor #12
O-GlcNAcylation, an Epigenetic Mark. Focus on the Histone Code, TET Family Proteins, and Polycomb Group Proteins
201484 citationsauthor #3
Insulin signaling controls the expression of O‐GlcNAc transferase and its interaction with lipid microdomains
201350 citationsauthor #9
Antibodies and activity measurements for the detection of O-GlcNAc transferase and assay of its substrate, UDP-GlcNAc.
20134 citationsauthor #1
proliferation -catenin and cell β -GlcNAcylation drive the expression of O The hexosamine biosynthetic pathway and
20130 citationsauthor #3
O-GlcNAcylation: A New Cancer Hallmark?
2013239 citationsauthor #3
Proteomics and PUGNAcity will overcome questioning of insulin resistance induction by nonselective inhibition of O‐GlcNAcase
20136 citationsauthor #2
Accepted Article Proteomics and PUGNAcity will overcome questioning of insulin resistance induction by non-selective inhibition of O-GlcNAcase.
20130 citationsauthor #2
PUGNAc treatment leads to an unusual accumulation of free oligosaccharides in CHO cells.
201223 citationsauthor #5
Neurodegeneration: Recall sugars, forget Alzheimer's.
20127 citationsauthor #1
Characterization of O-GlcNAc cycling and proteomic identification of differentially O-GlcNAcylated proteins during G1/S transition.
201265 citationsauthor #7
Serum-stimulated cell cycle entry promotes ncOGT synthesis required for cyclin D expression
201255 citationsauthor #9
O-GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
2011204 citationsauthor #10
Direct evidence of O-GlcNAcylation in the apicomplexan Toxoplasma gondii: a biochemical and bioinformatic study
201135 citationsauthor #8
the expression of β-catenin and cell proliferation
20110 citationsauthor #7
Arginine 469 is a pivotal residue for the Hsc70-GlcNAc-binding property.
20105 citationsauthor #7
Dysregulation of the nutrient/stress sensor O-GlcNAcylation is involved in the etiology of cardiovascular disorders, type-2 diabetes and Alzheimer's disease.
2010110 citationsauthor #1
Survey of O-GlcNAc level variations in Xenopus laevis from oogenesis to early development
200925 citationsauthor #2
Identification of Structural and Functional O-Linked N-Acetylglucosamine-bearing Proteins in Xenopus laevis Oocyte*S
200883 citationsauthor #9
Microinjection of recombinant O-GlcNAc transferase potentiates Xenopus oocytes M-phase entry.
200842 citationsauthor #8
Protein ubiquitination is modulated by O‐GlcNAc glycosylation
2008108 citationsauthor #7
O-Linked N-Acetylglucosaminyltransferase Inhibition Prevents G2/M Transition in Xenopus laevis Oocytes*
200769 citationsauthor #2
Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding.
200738 citationsauthor #6
Increased chromatin association of Sp1 in interphase cells by PP2A-mediated dephosphorylations.
200632 citationsauthor #2
Modulation of HSP70 GlcNAc-directed lectin activity by glucose availability and utilization.
200636 citationsauthor #5
Increased SP1 overall chromatin recruitment in divising cells by coordinated PP2A-mediated dephosphorylation
20060 citationsauthor #2
O-GlcNAc glycosylation: a signal for the nuclear transport of cytosolic proteins?
200583 citationsauthor #4
Does O-GlcNAc play a role in neurodegenerative diseases?
200556 citationsauthor #1
Modulation of O‐GlcNAc glycosylation during Xenopus oocyte maturation
200445 citationsauthor #1
70-kDa-heat shock protein presents an adjustable lectinic activity towards O-linked N-acetylglucosamine.
200460 citationsauthor #4
Identification of O-linked N-Acetylglucosamine Proteins in Rat Skeletal Muscle Using Two-dimensional Gel Electrophoresis and Mass Spectrometry*
2004101 citationsauthor #3
The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated.
200434 citationsauthor #1
Evidence of a balance between phosphorylation and O-GlcNAc glycosylation of Tau proteins--a role in nuclear localization.
2003200 citationsauthor #1
O-GlcNAc glycosylation and neurological disorders.
200320 citationsauthor #1
Function and Molecular Modeling of the Interaction between Human Interleukin 6 and Its HNK-1 Oligosaccharide Ligands*
200226 citationsauthor #6
O‐glycosylation of the nuclear forms of Pax‐6 products in quail neuroretina cells
200225 citationsauthor #1

TIMELINE

2002 51 citations

2003 220 citations

2004 240 citations

2005 139 citations

2006 68 citations

2007 107 citations

2008 233 citations

2009 25 citations

2010 115 citations

2011 239 citations

2012 150 citations

2013 299 citations

2014 330 citations

2015 95 citations

2016 212 citations

2017 253 citations

2018 248 citations

2019 68 citations

2020 17 citations

2021 101 citations

2022 18 citations

2023 96 citations

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