Protein ubiquitination is modulated by O‐GlcNAc glycosylation

No abstract is available for this paper.

• Publication year

  2008

• Venue

  The FASEB Journal

• Publication date

  2008-08-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1096/fj.07-102509PMID 18434435
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology.

  2008cited by this paper
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  2006cited by this paper
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  2006cited by this paper
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  2005cited by this paper
• The Hexosamine Signaling Pathway: Deciphering the "O-GlcNAc Code"

  2005cited by this paper
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  2005cited by this paper
• OGT functions as a catalytic chaperone under heat stress response: a unique defense role of OGT in hyperthermia.

  2004cited by this paper
• 70-kDa-heat shock protein presents an adjustable lectinic activity towards O-linked N-acetylglucosamine.

  2004influential reference
• O-GlcNAc a sensor of cellular state: the role of nucleocytoplasmic glycosylation in modulating cellular function in response to nutrition and stress.

  2004cited by this paper
• Dynamic O-GlcNAc Modification of Nucleocytoplasmic Proteins in Response to Stress

  2004influential reference
• O-GlcNAc modification: a nutritional sensor that modulates proteasome function.

  2004cited by this paper
• MDM2 Is a Negative Regulator of p21WAF1/CIP1, Independent of p53*

  2004cited by this paper
• High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.

  2003cited by this paper
• O-GlcNAc modification is an endogenous inhibitor of the proteasome.

  2003cited by this paper
• High glucose and insulin promote O-GlcNAc modification of proteins, including α-tubulin

  2003cited by this paper
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  2003cited by this paper
• Diverse regulation of protein function by O-GlcNAc: a nuclear and cytoplasmic carbohydrate post-translational modification.

  2002cited by this paper
• Dynamic interplay between O-glycosylation and O-phosphorylation of nucleocytoplasmic proteins: alternative glycosylation/phosphorylation of THR-58, a known mutational hot spot of c-Myc in lymphomas, is regulated by mitogens.

  2002cited by this paper
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  2001cited by this paper
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  2001cited by this paper
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  2001cited by this paper
• Alternative O-glycosylation/O-phosphorylation of serine-16 in murine estrogen receptor beta: post-translational regulation of turnover and transactivation activity.

  2001cited by this paper
• Identification of N-acetyl-d-glucosamine-specific lectins from rat liver cytosolic and nuclear compartments as heat-shock proteins.

  2001cited by this paper
• Cytosolic O‐glycosylation is abundant in nerve terminals

  2001cited by this paper
• Protein glucosylation and its role in protein folding.

  2000cited by this paper
• 'Glyco-deglyco' processes during the synthesis of N-glycoproteins.

  1998cited by this paper
• Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility

  1997cited by this paper
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  1996cited by this paper

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  2023cites this paper
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  2020cites this paper
• Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation

  2019cites this paper
• Regulation of hyaluronan biosynthesis and clinical impact of excessive hyaluronan production.

  2018cites this paper
• O-Linked β-N-acetylglucosamine (O-GlcNAc) modification: a new pathway to decode pathogenesis of diabetic retinopathy.

  2018cites this paper
• O-Linked N-Acetylglucosamine Transiently Elevates in HeLa Cells during Mitosis

  2018cites this paper
• Demystifying O-GlcNAcylation: hints from peptide substrates

  2018influential citation
• The role of autophagy in age‐related macular degeneration

  2018cites this paper
• O-GlcNAcylation confers protection against Staphylococcus aureus infection in Caenorhabditis elegans through ubiquitination

  2018cites this paper
• The effect of silicon compounds on resistance of the rabbits

  2018cites this paper
• Critical observations that shaped our understanding of the function(s) of intracellular glycosylation (O‐GlcNAc)

  2018cites this paper
• The Many Ways by Which O-GlcNAcylation May Orchestrate the Diversity of Complex Glycosylations

  2018cites this paper
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  2018cites this paper
• Real Talk: The Inter-play Between the mTOR, AMPK, and Hexosamine Biosynthetic Pathways in Cell Signaling

  2018cites this paper
• Glucosamine abrogates the stem cell factor + endothelin-1-induced stimulation of melanogenesis via a deficiency in MITF expression due to the proteolytic degradation of CREB in human melanocytes

  2018cites this paper
• A genetic model to study O-GlcNAc cycling in immortalized mouse embryonic fibroblasts

  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2016cites this paper
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  2016cites this paper
• Roles of O-GlcNAc in chronic diseases of aging.

  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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  2015cites this paper
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  2014cites this paper
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• O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration.

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• Aberrant O-GlcNAcylated Proteins: New Perspectives in Breast and Colorectal Cancer

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• Decreased O-Linked GlcNAcylation Protects from Cytotoxicity Mediated by Huntingtin Exon1 Protein Fragment*

  2014cites this paper
• Functional O-GlcNAc modifications: Implications in molecular regulation and pathophysiology

  2014cites this paper
• Absorption, distribution and mechanism of action of SYSADOAS.

  2014cites this paper
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  2012cites this paper
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  2012cites this paper
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• Tandem mass spectrometry identifies many mouse brain O-GlcNAcylated proteins including EGF domain-specific O-GlcNAc transferase targets

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• Cardiac Transcription Factor Nkx2.5 Is Downregulated under Excessive O-GlcNAcylation Condition

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• O-GlcNAc transferase/host cell factor C1 complex regulates gluconeogenesis by modulating PGC-1α stability.

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  2010cites this paper