H. Fan

Biallelic variants in MAD2L1BP (p31comet) cause female infertility characterized by oocyte maturation arrest
20239 citationsauthor #15
A long-acting recombinant FSH supports high-quality mouse follicle development and oocyte maturation in vitro by co-ordinating somatic and germ cell transcriptomes.
20234 citationsauthor #6
Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors
202325 citationsauthor #14
Biallelic variants in MOS cause large polar body in oocyte and human female infertility.
202214 citationsauthor #7
Ultrasensitive Ribo-seq reveals translational landscapes during mammalian oocyte-to-embryo transition and pre-implantation development
2022134 citationsauthor #21
NAT10-mediated N4-acetylcytidine modification is required for meiosis entry and progression in male germ cells
202262 citationsauthor #16
RNA ligase RTCB regulates mRNA Alternative splicing and is required for mouse oocyte development and maintenance.
20226 citationsauthor #7
HMCES safeguards genome integrity and long-term self-renewal of hematopoietic stem cells during stress responses
20226 citationsauthor #14
PABPN1 functions as a hub in the assembly of nuclear poly(A) domains that are essential for mouse oocyte development
202234 citationsauthor #8
Revisiting ZAR proteins: the understudied regulator of female fertility and beyond
202220 citationsauthor #2
Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging
202223 citationsauthor #9
Translation regulatory factor BZW1 regulates preimplantation embryo development and compaction by restricting global non-AUG Initiation
20228 citationsauthor #8
Publisher Correction: Dynamic mRNA degradome analyses indicate a role of histone H3K4 trimethylation in association with meiosis-coupled mRNA decay in oocyte aging
20221 citationsauthor #9
Five questions toward mRNA degradation in oocytes and preimplantation embryos: when, who, to whom, how, and why?
202225 citationsauthor #2
Mutations in OOEP and NLRP5 identified in infertile patients with early embryonic arrest
202219 citationsauthor #5
Genome-wide map of R-loops reveals its interplay with transcription and genome integrity during germ cell meiosis
20228 citationsauthor #13
USP16-mediated histone H2A lysine-119 deubiquitination during oocyte maturation is a prerequisite for zygotic genome activation
202226 citationsauthor #9
The CNOT4 Subunit of the CCR4‐NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis
202131 citationsauthor #12
Oocyte meiosis-coupled poly(A) polymerase α phosphorylation and activation trigger maternal mRNA translation in mice
202126 citationsauthor #7
Biallelic variants in ZFP36L2 cause female infertility characterised by recurrent preimplantation embryo arrest
202121 citationsauthor #15
Lysophosphatidic acid improves oocyte quality during IVM by activating the ERK1/2 pathway in cumulus cells and oocytes.
202116 citationsauthor #9
Role of CxxC-finger protein 1 in establishing mouse oocyte epigenetic landscapes
202120 citationsauthor #9
Metabolic remodelling during early mouse embryo development
2021106 citationsauthor #22
Nuclear poly(A) binding protein 1 (PABPN1) mediates zygotic genome activation-dependent maternal mRNA clearance during mouse early embryonic development
202130 citationsauthor #6
Metabolic remodeling during murine early embryo development
20210 citationsauthor #22
Biallelic mutations in MOS cause female infertility characterized by human early embryonic arrest and fragmentation
202143 citationsauthor #22
Genome-wide decoupling of H2Aub and H3K27me3 in early mouse development
20210 citationsauthor #5
Genomewide decoupling of H2AK119ub1 and H3K27me3 in early mouse development.
202125 citationsauthor #8
Revisiting poly(A)‐binding proteins: Multifaceted regulators during gametogenesis and early embryogenesis
202119 citationsauthor #2
CNOT6/6L-mediated mRNA degradation in ovarian granulosa cells is a key mechanism of gonadotropin-triggered follicle development.
202122 citationsauthor #9
CXXC finger protein 1-mediated histone H3 lysine-4 trimethylation is essential for proper meiotic crossover formation in mice
202022 citationsauthor #9
Erk and MAPK signaling is essential for intestinal development through Wnt pathway modulation
202024 citationsauthor #11
Metformin inhibits testosterone-induced endoplasmic reticulum stress in ovarian granulosa cells via inactivation of p38 MAPK
2020108 citationsauthor #9
Erratum. Metformin inhibits testosterone-induced endoplasmic reticulum stress in ovarian granulosa cells via inactivation of p38 MAPK.
20202 citationsauthor #9
Function and Regulation of Histone H3 Lysine-4 Methylation During Oocyte Meiosis and Maternal-to-Zygotic Transition
202031 citationsauthor #3
ERK/MAPK signaling is essential for intestinal development through Wnt pathway modulation.
20206 citationsauthor #11
Positive Feedback Stimulation of Ccnb1 and Mos mRNA Translation by MAPK Cascade During Mouse Oocyte Maturation
202034 citationsauthor #3
Dynamics and clinical relevance of maternal mRNA clearance during the oocyte-to-embryo transition in humans
2020134 citationsauthor #9
PABPN1L mediates cytoplasmic mRNA decay as a placeholder during the maternal‐to‐zygotic transition
202050 citationsauthor #8
[Function and molecular mechanism of mitogen-activated protein kinase (MAPK) in regulating oocyte meiotic maturation and ovulation].
202016 citationsauthor #4
Selective inhibition of Tmem74 expression in BLA pyramidal neurons
20191 citationsauthor #12
Oocyte Meiotic Maturation
20199 citationsauthor #1
A story of birth and death: mRNA translation and clearance at the onset of maternal-to-zygotic transition in mammals†
2019144 citationsauthor #3
Functional coupling of Tmem74 and HCN1 channels regulates anxiety-like behavior in BLA neurons
201919 citationsauthor #12
ZAR1 and ZAR2 are required for oocyte meiotic maturation by regulating the maternal transcriptome and mRNA translational activation
2019106 citationsauthor #6
Maternal DCAF13 Regulates Chromatin Tightness to Contribute to Embryonic Development
201932 citationsauthor #4
RNA‐Binding Protein IGF2BP2/IMP2 is a Critical Maternal Activator in Early Zygotic Genome Activation
201979 citationsauthor #17
Characterization of zygotic genome activation-dependent maternal mRNA clearance in mouse
2019105 citationsauthor #9
The CRL4-DCAF13 ubiquitin E3 ligase supports oocyte meiotic resumption by targeting PTEN degradation
201941 citationsauthor #7
CFP1-dependent histone H3K4 trimethylation in murine oocytes facilitates ovarian follicle recruitment and ovulation in a cell-nonautonomous manner
201922 citationsauthor #8
CFP1 coordinates histone H3 lysine-4 trimethylation and meiotic cell cycle progression in mouse oocytes
201863 citationsauthor #9
Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis
201828 citationsauthor #3
DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development
201858 citationsauthor #10
CNOT6L couples the selective degradation of maternal transcripts to meiotic cell cycle progression in mouse oocyte
2018121 citationsauthor #13
Loss of oocyte Rps26 in mice arrests oocyte growth and causes premature ovarian failure
201843 citationsauthor #8
A combinatorial code for mRNA 3′-UTR-mediated translational control in the mouse oocyte
201858 citationsauthor #6
Mammalian nucleolar protein DCAF13 is essential for ovarian follicle maintenance and oocyte growth by mediating rRNA processing
201859 citationsauthor #11
CRL4DCAF2 negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis
201837 citationsauthor #8
CFP1 Regulates Histone H3K4 Trimethylation and Developmental Potential in Mouse Oocytes.
201789 citationsauthor #12
Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels
201744 citationsauthor #13
A MAPK cascade couples maternal mRNA translation and degradation to meiotic cell cycle progression in mouse oocytes
2017117 citationsauthor #7
Maternal DCAF2 is crucial for maintenance of genome stability during the first cell cycle in mice
201721 citationsauthor #8
The polycystic ovary syndrome-associated gene Yap1 is regulated by gonadotropins and sex steroid hormones in hyperandrogenism-induced oligo-ovulation in mouse
201747 citationsauthor #9
TET1 inhibits cell proliferation by inducing RASSF5 expression
201718 citationsauthor #5
Mitochondrial Function Regulated by Mitoguardin-1/2 Is Crucial for Ovarian Endocrine Functions and Ovulation
201717 citationsauthor #9
Protein synthesis and degradation are essential to regulate germline stem cell homeostasis in Drosophila testes
201652 citationsauthor #8
BTG4 is a meiotic cell cycle–coupled maternal-zygotic-transition licensing factor in oocytes
2016231 citationsauthor #13
Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis.
2016122 citationsauthor #9
Development and characterization of a novel long-acting recombinant follicle stimulating hormone agonist by fusing Fc to an FSH-β subunit.
201621 citationsauthor #10
Studying the Functions of TGF-β Signaling in the Ovary.
201613 citationsauthor #3
Oocyte-expressed yes-associated protein is a key activator of the early zygotic genome in mouse
2016132 citationsauthor #10
Correction: YAP Promotes Ovarian Cancer Cell Tumorigenesis and Is Indicative of a Poor Prognosis for Ovarian Cancer Patients
20167 citationsauthor #7
CRL4–DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation
201565 citationsauthor #5
ERK1/2 activities are dispensable for oocyte growth but are required for meiotic maturation and pronuclear formation in mouse.
201551 citationsauthor #6
CRL4(VprBP) E3 ligase promotes monoubiquitylation and chromatin binding of TET dioxygenases.
2015106 citationsauthor #8
CRL4DCAF1 is required in activated oocytes for follicle maintenance and ovulation.
201522 citationsauthor #4
High salt primes a specific activation state of macrophages, M(Na)
2015219 citationsauthor #14
LKB1 acts as a critical gatekeeper of ovarian primordial follicle pool
201545 citationsauthor #5
Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions
201529 citationsauthor #8
YAP/TEAD Co-Activator Regulated Pluripotency and Chemoresistance in Ovarian Cancer Initiated Cells
201475 citationsauthor #5
CBP-CITED4 is required for luteinizing hormone-triggered target gene expression during ovulation.
201429 citationsauthor #6
oocytes for follicle maintenance and ovulation
20140 citationsauthor #4
Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway.
201433 citationsauthor #10
Heng-Yu Fan Female Fertility MAPK 3 / 1 ( ERK 1 / 2 ) in Ovarian Granulosa Cells Are Essential for
20140 citationsauthor #1
YAP Promotes Ovarian Cancer Cell Tumorigenesis and Is Indicative of a Poor Prognosis for Ovarian Cancer Patients
2014151 citationsauthor #7
Death Domain-associated Protein DAXX Promotes Ovarian Cancer Development and Chemoresistance*
201360 citationsauthor #8
Specific Disruption of Tsc1 in Ovarian Granulosa Cells Promotes Ovulation and Causes Progressive Accumulation of Corpora Lutea
201327 citationsauthor #10
TOP2β is essential for ovarian follicles that are hypersensitive to chemotherapeutic drugs.
201322 citationsauthor #8
High-efficiency and heritable gene targeting in mouse by transcription activator-like effector nucleases
201390 citationsauthor #11
Selective Smad4 knockout in ovarian preovulatory follicles results in multiple defects in ovulation.
201358 citationsauthor #3
Phosphoinositide 3-kinase p110δ mediates estrogen- and FSH-stimulated ovarian follicle growth.
201345 citationsauthor #9
DNA Topoisomerase II Is Dispensable for Oocyte Meiotic Resumption but Is Essential for Meiotic Chromosome Condensation and Separation in Mice1
201327 citationsauthor #8
CRL4 Complex Regulates Mammalian Oocyte Survival and Reprogramming by Activation of TET Proteins
2013108 citationsauthor #11
Ubiquitin E3 Ligase CRL4CDT2/DCAF2 as a Potential Chemotherapeutic Target for Ovarian Surface Epithelial Cancer*
201379 citationsauthor #9
DAXX silencing suppresses mouse ovarian surface epithelial cell growth by inducing senescence and DNA damage.
201318 citationsauthor #8
Laser microbeam-induced DNA damage inhibits cell division in fertilized eggs and early embryos
201333 citationsauthor #7
Consequences of RAS and MAPK activation in the ovary: the good, the bad and the ugly.
201258 citationsauthor #1
Either Kras Activation or Pten Loss Similarly Enhance the Mutant CTNNB1-Induced Genetic Program to Promote Granulosa Cell Tumor Development in Ovary and Testis.
20110 citationsauthor #2
CCAAT/enhancer-binding proteins (C/EBP)-α and -β are essential for ovulation, luteinization, and the expression of key target genes.
2011142 citationsauthor #1
LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation.
201166 citationsauthor #3

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