HERC2 functions as an E3 ubiquitin ligase that targets BARD1-uncoupled BRCA1 for degradation through BRCA1 ubiquitination.

From HERC2 is an E3 ligase that targets BRCA1 for degradation. Confidence 0.97

SOURCE RECORD

Source paper
HERC2 is an E3 ligase that targets BRCA1 for degradation.
Confidence
0.97
Contributors
박진우 (dztg5apj7m) extractionB (s683577b42) reviewAK (4715169a40) review

LINKED CONCEPTS

herc2
protein, enzyme
brca1
protein, tumor suppressor
bard1
protein, binding partner
ubiquitination
post-translational modification

CLAIM MAP