Cytokine modulation in acute pancreatitis.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Hepato-Biliary-Pancreatic Surgery

• Publication date

  2001-06-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/S005340170016PMID 11455479
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Randomized controlled trial of the effect of early enteral nutrition on markers of the inflammatory response in predicted severe acute pancreatitis

  2000cited by this paper
• Acute Necrotizing Pancreatitis: Treatment Strategy According to the Status of Infection

  2000cited by this paper
• Inflammatory mediators in acute pancreatitis

  2000cited by this paper
• Cerulein upregulates ICAM-1 in pancreatic acinar cells, which mediates neutrophil adhesion to these cells.

  2000cited by this paper
• Tumor necrosis factor alpha triggers antiapoptotic mechanisms in rat pancreatic cells through pancreatitis-associated protein I activation.

  2000cited by this paper
• Cytokine regulation of chemokine (IL-8, MCP-1, and RANTES) gene expression in human pancreatic periacinar myofibroblasts.

  2000cited by this paper
• Chemokine receptors and their role in inflammation and infectious diseases.

  2000cited by this paper
• Inflammatory mediators in human acute pancreatitis: clinical and pathophysiological implications

  2000cited by this paper
• Investigation of the Interleukin 1 Gene Cluster and Its Association with Acute Pancreatitis

  2000cited by this paper
• Inhibition of p38 mitogen activate kinase attenuates the severity of pancreatitis-induced adult respiratory distress syndrome

  2000cited by this paper
• Treatment with neutralising antibody against cytokine induced neutrophil chemoattractant (CINC) protects rats against acute pancreatitis associated lung injury

  2000cited by this paper
• CCK stimulates mob-1 expression and NF-κB activation via protein kinase C and intracellular Ca2+

  2000cited by this paper
• Activation of pancreatic acinar cells on isolation from tissue: cytokine upregulation via p38 MAP kinase.

  2000cited by this paper
• Relationship Between Plasma Cytokine Concentration and Multiple Organ Failure in Patients with Acute Pancreatitis

  2000cited by this paper
• Temporal correlation of tumor necrosis factor-alpha release, upregulation of pulmonary ICAM-1 and VCAM-1, neutrophil sequestration, and lung injury in diet-induced pancreatitis

  2000cited by this paper
• Quantitative measurement of P- and E-selectin adhesion molecules in acute pancreatitis: correlation with distant organ injury.

  2000cited by this paper
• Pancreatic elastase activates pulmonary nuclear factor kappa B and inhibitory kappa B, mimicking pancreatitis-associated adult respiratory distress syndrome.

  2000cited by this paper
• Inhibition of nuclear factor-κB activation improves the survival of rats with taurocholate pancreatitis

  1999cited by this paper
• Systemic lymphocyte activation modulates the severity of diet-induced acute pancreatitis in mice.

  1999cited by this paper
• The role of intercellular adhesion molecule 1 and neutrophils in acute pancreatitis and pancreatitis-associated lung injury.

  1999cited by this paper
• p38 Map Kinase Is Expressed in the Pancreas and Is Immediately Activated following Cerulein Hyperstimulation

  1999cited by this paper
• Acute Pancreatitis: The Pathophysiological Role of Cytokines and Integrins

  1999cited by this paper
• A Novel Diamino-Pyridine Derivative Prevents Excessive Leukocyte Infiltration in Aggravation of Acute Necrotizing Pancreatitis

  1999cited by this paper
• Pro- and anti-inflammatory cytokines during acute severe pancreatitis: an early and sustained response, although unpredictable of death. Parisian Study Group on Acute Pancreatitis.

  1999cited by this paper
• Comparison of two polymorphisms of the interleukin-1 gene family: interleukin-1 receptor antagonist polymorphism contributes to susceptibility to severe sepsis.

  1999cited by this paper
• NF-kappaB activation in acute pancreatitis: protective, detrimental, or inconsequential?

  1999cited by this paper
• Interleukin-10 Signaling Blocks Inhibitor of κB Kinase Activity and Nuclear Factor κB DNA Binding*

  1999cited by this paper
• A Role for the p38 Mitogen-activated Protein Kinase/Hsp 27 Pathway in Cholecystokinin-induced Changes in the Actin Cytoskeleton in Rat Pancreatic Acini*

  1998cited by this paper
• Early NF-κB activation is associated with hormone-induced pancreatitis.

  1998cited by this paper
• Codistribution of TAP and the granule membrane protein GRAMP-92 in rat caerulein-induced pancreatitis.

  1998cited by this paper
• Intra-acinar cell activation of trypsinogen during caerulein-induced pancreatitis in rats.

  1998cited by this paper
• A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of  TNF, Lymphotoxin α, or the p55TNF-R

  1998cited by this paper
• The effects of neutrophil depletion on a completely noninvasive model of acute pancreatitis-associated lung injury

  1998cited by this paper
• Acute pancreatitis: the substantial human and financial costs

  1998cited by this paper
• TNF but not IL-1 decreases pancreatic acinar cell survival without affecting exocrine function: a study in the perfused human pancreas.

  1998cited by this paper
• Value of early blood Th-1 cytokine determination in predicting severity of acute pancreatitis.

  1998cited by this paper
• Mechanism of increased lung injury after acute pancreatitis in IL-10 knockout mice.

  1998cited by this paper
• Acute pancreatitis due to pyritinol: an immune-mediated phenomenon.

  1998cited by this paper
• Criteria for diagnosis of acute pancreatitis in Japan and clinical implications.

  1998cited by this paper
• The role of cytokines in the pathogenesis of acute pancreatitis.

  1998cited by this paper
• Interleukin 10 reduces the severity of acute pancreatitis in rats.

  1997cited by this paper
• p55 Tumor necrosis factor receptor fusion protein in the treatment of patients with severe sepsis and septic shock. A randomized controlled multicenter trial. Ro 45-2081 Study Group.

  1997cited by this paper
• Gene targeting demonstrates additive detrimental effects of interleukin 1 and tumor necrosis factor during pancreatitis.

  1997cited by this paper
• Specific changes in the pancreatic expression of the interleukin 1 family of genes during experimental acute pancreatitis.

  1997cited by this paper
• Role of cytokines and their inhibitors in acute pancreatitis.

  1997cited by this paper
• Pancreatic acinar cells produce, release, and respond to tumor necrosis factor-alpha. Role in regulating cell death and pancreatitis.

  1997cited by this paper
• Evidence for an unknown component of pancreatic ascites that induces adult respiratory distress syndrome through an interleukin-1 and tumor necrosis factor-dependent mechanism.

  1997cited by this paper
• The potential role of procalcitonin and interleukin 8 in the prediction of infected necrosis in acute pancreatitis

  1997cited by this paper
• Targeted disruption of the beta-chemokine receptor CCR1 protects against pancreatitis-associated lung injury.

  1997cited by this paper
• Interleukin‐6 Is a Useful Marker for Early Prediction of the Severity of Acute Pancreatitis

  1997cited by this paper
• Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis.

  1997cited by this paper
• Therapeutic modification of nuclear factor kappa B binding activity and tumor necrosis factor-alpha gene expression during acute biliary pancreatitis.

  1997cited by this paper
• Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group.

  1997cited by this paper
• Severity and Mortality of Experimental Pancreatitis Are Dependent on Interleukin-1 Converting Enzyme (ICE)

  1997cited by this paper
• A genomic polymorphism within the tumor necrosis factor locus influences plasma tumor necrosis factor-alpha concentrations and outcome of patients with severe sepsis.

  1996cited by this paper
• Circulating cytokine concentrations and outcome prediction in intensive care unit patients: still the tip of the iceberg?

  1996cited by this paper
• Timing of tumor necrosis factor antagonism is critical in determining outcome in murine lethal acute pancreatitis.

  1996cited by this paper
• Calcium Channel Blockade Inhibits Release of TNFα and Improves Survival in a Rat Model of Acute Pancreatitis

  1996cited by this paper
• Inhibition of TNFα improves survival in an experimental model of acute pancreatitis

  1996cited by this paper
• Treatment of septic shock with the tumor necrosis factor receptor:Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group.

  1996cited by this paper
• Anti-TNFalpha therapy improves survival and ameliorates the pathophysiologic sequelae in acute pancreatitis in the rat.

  1996cited by this paper
• Increased monocyte cytokine production in association with systemic complications in acute pancreatitis

  1996cited by this paper
• Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice.

  1996cited by this paper
• Cytokines and acute pancreatitis.

  1996cited by this paper
• Serum concentrations of inflammatory mediators related to organ failure in patients with acute pancreatitis

  1996cited by this paper
• Intrapancreatic interleukin-1beta gene expression by specific leukocyte populations during acute pancreatitis.

  1996cited by this paper
• Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation?

  1996cited by this paper
• The potential biological and clinical significance of the soluble tumor necrosis factor receptors.

  1996cited by this paper
• Decreased interleukin-2 production in murine acute pancreatitis: potential for immunomodulation.

  1996cited by this paper
• INTERSEPT: an international, multicenter, placebo-controlled trial of monoclonal antibody to human tumor necrosis factor-alpha in patients with sepsis. International Sepsis Trial Study Group.

  1996cited by this paper
• Proinflammatory cytokine release by peripheral blood mononuclear cells from patients with acute pancreatitis

  1996cited by this paper
• Interleukin-6 family of cytokines and gp130.

  1995cited by this paper
• Interleukin-1 receptor antagonist modifies the changes in vital organs induced by acute necrotizing pancreatitis in a rat experimental model.

  1995cited by this paper
• Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

  1995cited by this paper
• Interleukin-1 receptor antagonist decreases severity of experimental acute pancreatitis.

  1995cited by this paper
• Randomized, double‐blind phase II trial of Lexipafant, a platelet‐activating factor antagonist, in human acute pancreatitis

  1995cited by this paper
• Inflammatory mediators in acute pancreatitis

  1995cited by this paper
• Lymphatic release of cytokines during acute lung injury complicating severe pancreatitis.

  1995cited by this paper
• Induction of acute pancreatitis in germ-free rats: evidence of a primary role for tumor necrosis factor-alpha.

  1995cited by this paper
• Acute pancreatitis induces intrapancreatic tumor necrosis factor gene expression.

  1995cited by this paper
• Interleukin-8 and the chemokine family.

  1995cited by this paper
• Up-regulation of TNFα mRNA in the rat spleen following induction of acute pancreatitis

  1995cited by this paper
• Efficacy and safety of monoclonal antibody to human tumor necrosis factor alpha in patients with sepsis syndrome. A randomized, controlled, double-blind, multicenter clinical trial. TNF-alpha MAb Sepsis Study Group.

  1995cited by this paper
• Decreased Mortality of Severe Acute Pancreatitis After Proximal Cytokine Blockade

  1995cited by this paper
• Localization of transforming growth factor β1 and its latent binding protein in human chronic pancreatitis

  1995cited by this paper
• Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study Group.

  1994cited by this paper
• Pathology of the pancreas in severe combined immunodeficiency and DiGeorge syndrome: acute graft-versus-host disease and unusual viral infections.

  1994cited by this paper
• Behavior of serum soluble interleukin-2 receptor, soluble CD8 and soluble CD4 in the early phases of acute pancreatitis.

  1994cited by this paper
• Induction of tumor necrosis factor in severe acute pancreatitis and its subsequent reduction after hepatic passage.

  1994cited by this paper
• Amelioration of the physiologic and biochemical changes of acute pancreatitis using an anti-TNF-alpha polyclonal antibody.

  1994cited by this paper
• Role of interleukin-6 in mediating the acute phase protein response and potential as an early means of severity assessment in acute pancreatitis.

  1993cited by this paper
• Arterial constriction, ischemia-reperfusion, and leukocyte adherence in acute pancreatitis.

  1993cited by this paper
• NF-kappa B and Rel: participants in a multiform transcriptional regulatory system.

  1993cited by this paper
• Distinct NF-κB/Rel transcription factors are responsible for tissue-specific and inducible gene activation

  1993cited by this paper
• Inflammatory mediators and cytokines--new aspects of the pathophysiology and assessment of severity of acute pancreatitis?

  1993cited by this paper
• Evaluation of severity in patients with acute pancreatitis.

  1992cited by this paper
• lnterleukin‐8 and neutrophil activation in acute pancreatitis

  1992cited by this paper
• Influence of levamisole on pancreatic infection in acute pancreatitis.

  1992cited by this paper
• Elevation of serum interleukin-6 concentration precedes acute-phase response and reflects severity in acute pancreatitis.

  1991cited by this paper
• Anti-tumor necrosis factor antibody augments edema formation in caerulein-induced acute pancreatitis.

  1991cited by this paper

• Changes in cytokines and chemokines in an acute pancreatitis model

  2024cites this paper
• Decreased levels of regulatory B cells in patients with acute pancreatitis: association with the severity of the disease

  2018cites this paper
• Nicotine Ameliorates Experimental Severe Acute Pancreatitis via Enhancing Immunoregulation of CD4+ CD25+Regulatory T Cells

  2015cites this paper
• The protective effects of taurine on experimental acute pancreatitis in a rat model

  2013cites this paper
• severe acute pancreatitis Protective roles of redox-active protein thioredoxin-1 for

  2013cites this paper
• Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats.

  2013cites this paper
• Insulin resistance and adipocytokine levels in patients with acute pancreatitis

  2012cites this paper
• Ameliorative Effect of Adalimumab on Experimentally Induced Acute Pancreatitis in Rats

  2010cites this paper
• Effects of etanercept on sodium taurocholate-induced acute pancreatitis in rats.

  2009cites this paper
• Establishment of the critical period of severe acute pancreatitis-associated lung injury.

  2009cites this paper
• Cross-talk between oxidative stress and pro-inflammatory cytokines in acute pancreatitis: a key role for protein phosphatases.

  2009cites this paper
• Blocking of monocyte chemoattractant protein-1 (MCP-1) activity attenuates the severity of acute pancreatitis in rats

  2008cites this paper
• Statin pretreatment in experimental acute pancreatitis.

  2008cites this paper
• Marcadores de gravedad en la pancreatitis aguda

  2007cites this paper
• [Markers of severity in acute pancreatitis].

  2007cites this paper
• From Acute Pancreatitis to End-Organ Injury: Mechanisms of Acute Lung Injury

  2007cites this paper
• Protective roles of redox-active protein thioredoxin-1 for severe acute pancreatitis.

  2006cites this paper
• Progress in research into the mechanism of Radix salviae miltiorrhizae in treatment of acute pancreatitis.

  2006cites this paper
• Clinical Significance of Serum Thioredoxin 1 Levels in Patients with Acute Pancreatitis

  2006cites this paper
• Cellular and molecular events in acute pancreatitis

  2006cites this paper
• Bases moleculares de la depleción de glutatión y de la necrosis celular en la pancreatitis aguda. Papel de las proteín quinasas activadas por mitógenos.

  2006cites this paper
• Tumor necrosis factor α antibody prevents brain damage of rats with acute necrotizing pancreatitis

  2004cites this paper
• Novel understanding of pathophysiology and potential intervention in acute pancreatitis based on studies of gene‐modified mice

  2004cites this paper
• Tumor necrosis factor alpha antibody prevents brain damage of rats with acute necrotizing pancreatitis.

  2004cites this paper
• Effect of NF-kappaB and p38 MAPK in activated monocytes/macrophages on pro-inflammatory cytokines of rats with acute pancreatitis.

  2003cites this paper
• Effect of NF- k B and p38 MAPK in activated monocytes/macrophages on pro-inflammatory cytokines of rats with acute pancreatitis

  2003cites this paper
• Clinical relevance of intracellular cytokines IL-6 and IL-12 in acute pancreatitis, and correlation with APACHE III score

  2002cites this paper
• A patient with severe acute pancreatitis successfully treated with a new critical care procedure.

  2002cites this paper