Neuromedin U and Its Putative Drosophila Homolog hugin

C. Melcher,Rüdiger Bader,S. Walther,O. Simakov,M. Pankratz

Published 2006 in PLoS Biology

ABSTRACT

We recently provided a molecular, neuroanatomical, and behavioral analyses of neurons expressing the neuropeptide gene hugin in Drosophila [1]. hugin-expressing neurons appear to comprise a neural circuitry in the brain that modulates feeding behavior in response to gustatory and nutrient signals. One of the questions arising from this study was whether a mammalian homolog of hugin exists. We argue here that a mammalian homolog of Drosophila hugin may be neuromedin U (NmU).

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