Zinc-binding structure of a catalytic amyloid from solid-state NMR

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2017-05-25

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1073/pnas.1706179114PMID 28566494PMCID PMC5474797
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2014influential reference
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• Structural bioinformatics Advance Access publication April 5, 2011 ProDy: Protein Dynamics Inferred from Theory and Experiments

  2010influential reference
• Perspectives in paramagnetic NMR of metalloproteins.

  2008cited by this paper
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• Carbonic Anhydrase: Evolution of the Zinc Binding Site by Nature and by Design

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