Action of insulin receptor substrate-3 (IRS-3) and IRS-4 to stimulate translocation of GLUT4 in rat adipose cells.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Molecular Endocrinology

• Publication date

  1999-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1210/MEND.13.3.0242PMID 10077007
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Withers, D. J. et al. Disruption of IRS-2 causes type 2 diabetes in mice. Nature 391, 900-904

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• Disruption of IRS-2 causes type 2 diabetes in mice

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• Targeting of Constitutively Active Phosphoinositide 3-Kinase to GLUT4-containing Vesicles in 3T3-L1 Adipocytes*

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• Characterization of Insulin Receptor Substrate 4 in Human Embryonic Kidney 293 Cells*

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• Dynamics of Insulin Signaling in 3T3-L1 Adipocytes

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• Differential effects of constitutively active phosphatidylinositol 3-kinase on glucose transport, glycogen synthase activity, and DNA synthesis in 3T3-L1 adipocytes

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• Protein-tyrosine Phosphatases PTP1B and Syp Are Modulators of Insulin-stimulated Translocation of GLUT4 in Transfected Rat Adipose Cells*

  1997cited by this paper
• The 60-kDa Phosphotyrosine Protein in Insulin-treated Adipocytes Is a New Member of the Insulin Receptor Substrate Family*

  1997cited by this paper
• The 60 kDa insulin receptor substrate functions like an IRS protein (pp60IRS3) in adipose cells.

  1997cited by this paper
• A Novel 160-kDa Phosphotyrosine Protein in Insulin-treated Embryonic Kidney Cells Is a New Member of the Insulin Receptor Substrate Family*

  1997cited by this paper
• Role of Insulin Receptor Substrate-1 and pp60 in the Regulation of Insulin-induced Glucose Transport and GLUT4 Translocation in Primary Adipocytes*

  1997cited by this paper
• Cloning, tissue expression, and chromosomal localization of the mouse IRS-3 gene.

  1997cited by this paper
• Insulin Receptor Substrate-2 (IRS-2) Can Mediate the Action of Insulin to Stimulate Translocation of GLUT4 to the Cell Surface in Rat Adipose Cells*

  1997cited by this paper
• Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes

  1997cited by this paper
• Insulin receptor substrate (IRS) 1 is reduced and IRS-2 is the main docking protein for phosphatidylinositol 3-kinase in adipocytes from subjects with non-insulin-dependent diabetes mellitus.

  1997cited by this paper
• Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes*

  1996cited by this paper
• Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation.

  1996cited by this paper
• Insulin-mediated Targeting of Phosphatidylinositol 3-Kinase to GLUT4-containing Vesicles (*)

  1996cited by this paper
• Activated Phosphatidylinositol 3-Kinase Is Sufficient to Mediate Actin Rearrangement and GLUT4 Translocation in 3T3-L1 Adipocytes*

  1996cited by this paper
• A Grb2-associated docking protein in EGF- and insulin-receptor signalling

  1996cited by this paper
• The PI/PTB domain: a new protein interaction domain involved in growth factor receptor signaling.

  1996cited by this paper
• Interaction between the Phosphotyrosine Binding Domain of Shc and the Insulin Receptor Is Required for Shc Phosphorylation by Insulin in Vivo(*)

  1996cited by this paper
• Overexpression of Catalytic Subunit p110α of Phosphatidylinositol 3-Kinase Increases Glucose Transport Activity with Translocation of Glucose Transporters in 3T3-L1 Adipocytes*

  1996cited by this paper
• Phosphotyrosine-dependent interaction of SHC and insulin receptor substrate 1 with the NPEY motif of the insulin receptor via a novel non-SH2 domain

  1995cited by this paper
• Role of IRS-2 in insulin and cytokine signalling

  1995cited by this paper
• Insulin Regulation of Membrane-associated Insulin Receptor Substrate 1 (*)

  1995cited by this paper
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  1995cited by this paper
• PTB domain binding to signaling proteins through a sequence motif containing phosphotyrosine.

  1995cited by this paper
• Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells

  1995cited by this paper
• Erratum: Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene (Nature (1994) 372 (186-190))

  1994cited by this paper
• Insulin receptor substrate 1 mediates the stimulatory effect of insulin on GLUT4 translocation in transfected rat adipose cells.

  1994cited by this paper
• Tyrosine kinase-deficient mutant human insulin receptors (Met1153-->Ile) overexpressed in transfected rat adipose cells fail to mediate translocation of epitope-tagged GLUT4.

  1994cited by this paper
• Insulin signal transduction pathways.

  1994cited by this paper
• Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

  1994cited by this paper
• Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

  1994cited by this paper
• Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

  1994cited by this paper
• Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

  1994cited by this paper
• Regulation of the GLUT4/muscle-fat glucose transporter mRNA in adipose tissue of insulin-deficient diabetic rats.

  1993cited by this paper
• Phosphatidylinositol-3-kinase in isolated rat adipocytes. Activation by insulin and subcellular distribution.

  1992cited by this paper
• A generic intron increases gene expression in transgenic mice

  1991cited by this paper
• Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

  1991cited by this paper
• Hepatocyte plasma membrane ECTO-ATPase (pp120/HA4) is a substrate for tyrosine kinase activity of the insulin receptor.

  1990cited by this paper
• Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor.

  1989cited by this paper
• Human diabetes associated with a mutation in the tyrosine kinase domain of the insulin receptor

  1989cited by this paper
• Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity.

  1988cited by this paper
• At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells.

  1987cited by this paper
• cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.

  1985cited by this paper
• Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor.

  1982cited by this paper

• Is Insulin Receptor Substrate4 (IRS4) a Platform Involved in the Activation of Several Oncogenes?

  2023cites this paper
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  2022cites this paper
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  2021cites this paper
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  2020cites this paper
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  2019cites this paper
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  2018cites this paper
• The interaction of auraptene and other oxyprenylated phenylpropanoids with glucose transporter type 4.

  2017cites this paper
• IRS-2 Partially Compensates for the Insulin Signal Defects in IRS-1−/− Mice Mediated by miR-33

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2010cites this paper
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  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2007cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  1999cites this paper
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  1999cites this paper
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