Adenovirus type 12 early region 1B 54K protein significantly extends the life span of normal mammalian cells in culture

No abstract is available for this paper.

• Publication year

  1997

• Venue

  Journal of Virology

• Publication date

  1997-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/jvi.71.9.6629-6640.1997PMID 9261385PMCID PMC191941
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Evidence that transcriptional activation by p53 plays a direct role in the induction of cellular senescence.

  1996cited by this paper
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• The CBP co-activator is a histone acetyltransferase

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• Control of p53 expression by adenovirus 12 early region 1A and early region 1B 54K proteins.

  1996cited by this paper
• Abnormal Centrosome Amplification in the Absence of p53

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  1996cited by this paper
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  1995cited by this paper
• A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

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• The high levels of p53 present in adenovirus early region 1-transformed human cells do not cause up-regulation of MDM2 expression.

  1995cited by this paper
• Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53.

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• MECHANISMS OF HUMAN CELL NEOPLASTIC TRANSFORMATION: RELATIONSHIP OF SPECIFIC ABNORMAL CLONE FORMATION TO PROLONGED LIFESPAN IN X‐IRRADIATED HUMAN DIPLOID FIBROBLASTS

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