Detection of N-acylhomoserine lactones in lung tissues of mice infected with Pseudomonas aeruginosa.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Microbiology

• Publication date

  2000-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1099/00221287-146-10-2481PMID 11021924
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The apparent clock-like evolution of Escherichia coli in glucose-limited chemostats is reproducible at large but not at small population sizes and can be explained with Monod kinetics.

  2002cited by this paper
• Lung Infections Associated with Cystic Fibrosis

  2002cited by this paper
• Production of N-acyl-L-homoserine lactones by P. aeruginosa isolates from chronic lung infections associated with cystic fibrosis.

  2000cited by this paper
• Nosocomial pneumonia in the ICU--year 2000 and beyond.

  1999cited by this paper
• Active Efflux and Diffusion Are Involved in Transport of Pseudomonas aeruginosa Cell-to-Cell Signals

  1999cited by this paper
• Quorum Sensing: the Explanation of a Curious Phenomenon Reveals a Common Characteristic of Bacteria

  1999cited by this paper
• Roles of Pseudomonas aeruginosa las andrhl Quorum-Sensing Systems in Control of Twitching Motility

  1999cited by this paper
• Cell-to-cell signaling and Pseudomonas aeruginosa infections.

  1998cited by this paper
• Quorum sensing: potential means of treating gram-negative infections?

  1998influential reference
• Quorum sensing: a novel target for anti-infective therapy.

  1998cited by this paper
• The involvement of cell-to-cell signals in the development of a bacterial biofilm.

  1998cited by this paper
• Cell-to-cell signaling and Pseudomonas aeruginosa infections.

  1998cited by this paper
• Self perception in bacteria: quorum sensing with acylated homoserine lactones.

  1998influential reference
• Quorum sensing and the cell-cell communication dependent regulation of gene expression in pathogenic and non-pathogenic bacteria

  1998cited by this paper
• New Unstable Variants of Green Fluorescent Protein for Studies of Transient Gene Expression in Bacteria

  1998cited by this paper
• The Pseudomonas aeruginosaQuorum-Sensing Signal MoleculeN-(3-Oxododecanoyl)-l-Homoserine Lactone Has Immunomodulatory Activity

  1998cited by this paper
• Quorum sensing: a novel target for anti-infective therapy.

  1998cited by this paper
• Effects of Ginseng Treatment on Neutrophil Chemiluminescence and Immunoglobulin G Subclasses in a Rat Model of Chronic Pseudomonas aeruginosa Pneumonia

  1998cited by this paper
• Regulation of the xcp secretion pathway by multiple quorum‐sensing modulons in Pseudomonas aeruginosa

  1997cited by this paper
• Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-acylhomoserine lactone signal molecules

  1997influential reference
• Chronic Pseudomonas aeruginosa lung infection is more severe in Th2 responding BALB/c mice compared to Th1 responding C3H/HeN mice

  1997cited by this paper
• Roles of Pseudomonas aeruginosa las and rhl quorum-sensing systems in control of elastase and rhamnolipid biosynthesis genes

  1997cited by this paper
• Detecting and characterizing N-acyl-homoserine lactone signal molecules by thin-layer chromatography.

  1997influential reference
• Census and consensus in bacterial ecosystems: the LuxR-LuxI family of quorum-sensing transcriptional regulators.

  1996cited by this paper
• Copyright © 1997, American Society for Microbiology Regulation of las and rhl Quorum Sensing in Pseudomonas aeruginosa

  1996cited by this paper
• Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia.

  1996cited by this paper
• FACS-optimized mutants of the green fluorescent protein (GFP).

  1996cited by this paper
• Eukaryotic interference with homoserine lactone-mediated prokaryotic signalling

  1996cited by this paper
• Pulmonary infiltrates in the cancer patient. New approaches to an old problem.

  1996cited by this paper
• Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection

  1996cited by this paper
• A hierarchical quorum‐sensing cascade in Pseudomonas aeruginosa links the transcriptional activators LasR and RhIR (VsmR) to expression of the stationary‐phase sigma factor RpoS

  1996cited by this paper
• Multiple N-acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa.

  1995cited by this paper
• Autoinducer-mediated regulation of rhamnolipid biosurfactant synthesis in Pseudomonas aeruginosa.

  1995cited by this paper
• A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa.

  1995cited by this paper
• Synthesis of multiple exoproducts in Pseudomonas aeruginosa is under the control of RhlR-RhlI, another set of regulators in strain PAO1 with homology to the autoinducer-responsive LuxR-LuxI family

  1995cited by this paper
• Activation of the Pseudomonas aeruginosa lasI gene by LasR and the Pseudomonas autoinducer PAI: an autoinduction regulatory hierarchy

  1995cited by this paper
• The bacterial ‘enigma’: cracking the code of cell–cell communication

  1995cited by this paper
• Pseudomonas aeruginosa outbreak in a burn unit: role of antimicrobials in the emergence of multiply resistant strains.

  1994cited by this paper
• Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes.

  1994influential reference
• Expression of Pseudomonas aeruginosa virulence genes requires cell-to-cell communication.

  1993cited by this paper
• Pathogenesis of cystic fibrosis.

  1993cited by this paper
• Pathogenesis of cystic fibrosis

  1993cited by this paper
• Chronic Pseudomonas aeruginosa lung infection in normal and athymic rats

  1993cited by this paper
• LasR of Pseudomonas aeruginosa is a transcriptional activator of the alkaline protease gene (apr) and an enhancer of exotoxin A expression

  1993cited by this paper
• A small diffusible signal molecule is responsible for the global control of virulence and exoenzyme production in the plant pathogen Erwinia carotovora.

  1993cited by this paper
• Complement activation by Pseudomonas aeruginosa biofilms.

  1993cited by this paper
• The lux autoinducer regulates the production of exoenzyme virulence determinants in Erwinia carotovora and Pseudomonas aeruginosa.

  1993cited by this paper
• Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression

  1991cited by this paper
• Induction of experimental chronic Pseudomonas aeruginosa lung infection with P. aeruginosa entrapped in alginate microspheres

  1990cited by this paper
• Immunohistopathologic localization of Pseudomonas aeruginosa in lungs from patients with cystic fibrosis. Implications for the pathogenesis of progressive lung deterioration.

  1989influential reference
• New approaches to an old problem

  1988cited by this paper
• Bacterial biofilms in nature and disease.

  1987cited by this paper
• Demonstration of neutrophil chemotactic activity in the sputum of cystic fibrosis patients with Pseudomonas aeruginosa infection

  1986influential reference
• Genome organization in Pseudomonas.

  1986cited by this paper
• Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors.

  1985cited by this paper
• Received

  1868cited by this paper

• In Vitro and In Silico Assessment of the Probiotic and Technological Potential of Lacticaseibacillus rhamnosus MW019593 Isolated from Algerian Cow's Milk.

  2025cites this paper
• Anti-Pseudomonas aeruginosa Vaccines and Therapies: An Assessment of Clinical Trials

  2023cites this paper
• New dynamic microreactor system to mimic biofilm formation and test anti-biofilm activity of nanoparticles

  2022cites this paper
• Impact of Quorum Sensing System on Virulence Factors Production in Pseudomonas aeruginosa

  2022cites this paper
• N-acyl homoserine lactone molecules assisted quorum sensing: effects consequences and monitoring of bacteria talking in real life

  2021cites this paper
• Baicalin Represses Type Three Secretion System of Pseudomonas aeruginosa through PQS System

  2021cites this paper
• Revisiting the virulence hallmarks of Pseudomonas aeruginosa: A chronicle through the perspective of quorum sensing.

  2021cites this paper
• Quorum sensing and quorum quenching in membrane bioreactors

  2020cites this paper
• Antibiotic resistance of bacterial biofilms 1 2 3

  2019cites this paper
• Imaging N-Acyl Homoserine Lactone Quorum Sensing In Vivo.

  2018cites this paper
• Title High -lactamase levels change the pharmacodynamics of -lactam antibiotics in pseudomonas aeruginosa biofilms

  2018cites this paper
• Enhancement of anti-fouling properties of quorum quenching bacteria entrapping media for effective biofouling control in membrane bioreactors

  2017cites this paper
• Design of artificial functional and regulatory systems in bacteria

  2017cites this paper
• Crystal structure of the N-terminal domain of VqsR from Pseudomonas aeruginosa at 2.1 Å resolution.

  2017cites this paper
• Opportunities for applying whole‐cell bioreporters towards parasite detection

  2017cites this paper
• Bacterial Biofilm and Antibiotic Resistance

  2017cites this paper
• Transcriptional control of quorum sensing and associated metabolic interactions in Pseudomonas syringae strain B728a

  2016influential citation
• Directed evolution of penicillin V acylase from "Streptomyces lavendulae" and aculeacin A acylase from "Actinoplanes utahensis"

  2016cites this paper
• Practical Application of Bacterial Quorum Quenching and Development of Quorum Quenching Medium for Biofouling Control in Membrane Bioreactor for Wastewater Treatment

  2016influential citation
• Antimicrobial production by Pectobacterium carotovorum subspecies brasiliensis and its role in competitive fitness of the potato pathogen

  2016cites this paper
• Magnetic molecularly imprinted polymer nanoparticles based electrochemical sensor for the measurement of Gram-negative bacterial quorum signaling molecules (N-acyl-homoserine-lactones).

  2016cites this paper
• Engineering Soluble Human Paraoxonase 2 for Quorum Quenching.

  2016cites this paper
• More Efficient Media Design for Enhanced Biofouling Control in a Membrane Bioreactor: Quorum Quenching Bacteria Entrapping Hollow Cylinder.

  2016cites this paper
• Effect of the Shape and Size of Quorum-Quenching Media on Biofouling Control in Membrane Bioreactors for Wastewater Treatment.

  2016influential citation
• Attenuation of quorum sensing-mediated virulence in Gram-negative pathogenic bacteria: implications for the post-antibiotic era

  2015cites this paper
• Xanthomonas campestris cell–cell signalling molecule DSF (diffusible signal factor) elicits innate immunity in plants and is suppressed by the exopolysaccharide xanthan

  2015influential citation
• Coordinating Gene Therapies of Cystic Fibrosis Airway Disease with Anti-Inflammatory and Antimicrobial Cationic Glucocorticoids

  2015cites this paper
• Pharmacokinetics and pharmacodynamics of antibiotics in biofilm infections of Pseudomonas aeruginosa in vitro and in vivo.

  2014cites this paper
• Development of quorum-sensing-based genetic circuits that enable programmable functionalities in escherichia coli

  2014cites this paper
• In Vivo Evaluation of Adeno-Associated Virus Gene Transfer in Airways of Mice with Acute or Chronic Respiratory Infection

  2014cites this paper
• Reversible non‐genetic phenotypic heterogeneity in bacterial quorum sensing

  2014cites this paper
• Development of an Ex Vivo Porcine Lung Model for Studying Growth, Virulence, and Signaling of Pseudomonas aeruginosa

  2014cites this paper
• Pseudomonas aeruginosa adaptation in the nasopharyngeal reservoir leads to migration and persistence in the lungs

  2014cites this paper
• Serum influences the expression of Pseudomonas aeruginosa quorum-sensing genes and QS-controlled virulence genes during early and late stages of growth

  2013cites this paper
• Next generation biofilm inhibitors for Pseudomonas aeruginosa: Synthesis and rational design approaches.

  2013cites this paper
• Quorum sensing

  2013cites this paper
• High beta-Lactamase Levels Change the Pharmacodynamics of beta-Lactam Antibiotics in Pseudomonas aeruginosa Biofilms

  2012cites this paper
• Quorum sensing and virulence of Pseudomonas aeruginosa during urinary tract infections.

  2012cites this paper
• In Vivo Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem in Pseudomonas aeruginosa Biofilm Infection

  2012cites this paper
• Impact of Pseudomonas aeruginosa quorum sensing on cellular wound healing responses in vitro

  2012cites this paper
• Quorum Sensing

  2012cites this paper
• High β-Lactamase Levels Change the Pharmacodynamics of β-Lactam Antibiotics in Pseudomonas aeruginosa Biofilms

  2012cites this paper
• Pharmacokinetics/Pharmacodynamics of Colistin and Imipenem on Mucoid and Nonmucoid Pseudomonas aeruginosa Biofilms

  2011cites this paper
• Magnetic particle induction and its importance in biofilm research

  2011cites this paper
• The clinical impact of bacterial biofilms

  2011cites this paper
• Mutation of pfm affects the adherence of Pseudomonas aeruginosa to host cells and the quorum sensing system.

  2011influential citation
• Occurrence of N-Acyl Homoserine Lactones in Extracts of Bacterial Strain of Pseudomonas aeruginosa and in Sputum Sample Evaluated by Gas Chromatography–Mass Spectrometry

  2011cites this paper
• Imaging N-acyl homoserine lactone quorum sensing in vivo.

  2011cites this paper
• Cable Pili and the Associated 22 Kda Adhesin Contribute to Burkholderia Cenocepacia Persistence In Vivo

  2011cites this paper
• CELL AND PROTEIN-BASED SENSING SYSTEMS FOR THE DETECTION OF ENVIRONMENTALLY AND PHYSIOLOGICALLY RELEVANT MOLECULES

  2011cites this paper
• Novel and Future Treatment Strategies

  2011cites this paper
• In vitro screens for quorum sensing inhibitors and in vivo confirmation of their effect

  2010cites this paper
• Eukaryotic vs. prokaryotic chemosensory systems.

  2010cites this paper
• Antibiotic resistance of bacterial biofilms.

  2010cites this paper
• Pseudomonas signal molecule 3-oxo-C12-homoserine lactone interferes with binding of rosiglitazone to human PPARgamma.

  2010cites this paper
• Garlic blocks quorum sensing and attenuates the virulence of Pseudomonas aeruginosa.

  2010cites this paper
• Construction of Self-Transmissible Green Fluorescent Protein-Based Biosensor Plasmids and Their Use for Identification of N-Acyl Homoserine-Producing Bacteria in Lake Sediments

  2010cites this paper
• Paper strip whole cell biosensors: a portable test for the semiquantitative detection of bacterial quorum signaling molecules.

  2010cites this paper
• Where microbiology meets microengineering: design and applications of reporter bacteria

  2010cites this paper
• N-acylhomoserine lactones involved in quorum sensing control the type VI secretion system, biofilm formation, protease production, and in vivo virulence in a clinical isolate of Aeromonas hydrophila.

  2009cites this paper
• Diagnostic significance of measurements of specific IgG antibodies to Pseudomonas aeruginosa by three different serological methods.

  2009cites this paper
• Quorum sensing inhibitors: a patent overview

  2009cites this paper
• Accurate mass analysis of N-acyl-homoserine-lactones and cognate lactone-opened compounds in bacterial isolates of Pseudomonas aeruginosa PAO1 by LC-ESI-LTQ-FTICR-MS.

  2009cites this paper
• Pseudomonas aeruginosa quorum-sensing signal molecules interfere with dendritic cell-induced T-cell proliferation.

  2009cites this paper
• Quorum sensing is necessary for the virulence of Pseudomonas aeruginosa during urinary tract infection.

  2009cites this paper
• Quorum sensing in veterinary pathogens: mechanisms, clinical importance and future perspectives.

  2009cites this paper
• Pathogenesis and clinical manifestations of chronic colonization by Pseudomonas aeruginosa and its biofilms in the airway tract

  2009cites this paper
• Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes.

  2009cites this paper
• Microbial quorum sensing: a tool or a target for antimicrobial therapy?

  2009cites this paper
• Detection of bacterial quorum sensing N-acyl homoserine lactones in clinical samples

  2008cites this paper
• Bench-to-bedside review: Quorum sensing and the role of cell-to-cell communication during invasive bacterial infection

  2008cites this paper
• Staphylococcus aureus Elicits Marked Alterations in the Airway Proteome during Early Pneumonia

  2008cites this paper
• Quorum size of Pseudomonas syringae is small and dictated by water availability on the leaf surface

  2008cites this paper
• Characterization of N-butanoyl-L-homoserine lactone (C4-HSL) deficient clinical isolates of Pseudomonas aeruginosa.

  2008cites this paper
• Detection of Pseudomonas aeruginosa quorum sensing signals in an infected ischemic wound: An experimental study in rats

  2008cites this paper
• Why chronic wounds will not heal: a novel hypothesis

  2008cites this paper
• Distribution, Organization, and Ecology of Bacteria in Chronic Wounds

  2008cites this paper
• Two Dissimilar N-Acyl-Homoserine Lactone Acylases of Pseudomonas syringae Influence Colony and Biofilm Morphology

  2008cites this paper
• Quorum-Sensing Inhibitory Compounds

  2008cites this paper
• Model socialite, problem pathogen: the evolution and ecology of cooperation in the bacterium Pseudomonas aeruginosa

  2008cites this paper
• Photoproteins as Reporters in Whole‐cell Sensing

  2008cites this paper
• The effects of Pseudomonas aeruginosa quorum sensing signalling molecules on human T cell function

  2008cites this paper
• Pseudomonas Aeruginosa: interactions with organisms in the environment and cells of the immune defence

  2008cites this paper
• Early Pneumonia Alterations in the Airway Proteome during Elicits Marked Staphylococcus Aureus Supplemental Material

  2008cites this paper
• Occurrence of N-acyl-L-homoserine lactones in extracts of some Gram-negative bacteria evaluated by gas chromatography-mass spectrometry.

  2007cites this paper
• Detection of quorum-sensing N-acyl homoserine lactone signal molecules by bacterial biosensors.

  2007cites this paper
• Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

  2007cites this paper
• Azithromycin Blocks Quorum Sensing and Alginate Polymer Formation and Increases the Sensitivity to Serum and Stationary-Growth-Phase Killing of Pseudomonas aeruginosa and Attenuates Chronic P. aeruginosa Lung Infection in Cftr−/− Mice

  2007cites this paper
• Animal models of chronic Pseudomonas aeruginosa lung infection in cystic fibrosis

  2007cites this paper
• Immune modulation by Pseudomonas aeruginosa quorum-sensing signal molecules.

  2006cites this paper
• Development and application of a method for the analysis of N-acylhomoserine lactones by solid-phase extraction and ultra high pressure liquid chromatography.

  2006cites this paper
• Quorum-sensing inhibitors as anti-pathogenic drugs.

  2006cites this paper
• Profiling of acylated homoserine lactones of Vibrio anguillarum in vitro and in vivo: Influence of growth conditions and serotype.

  2006cites this paper
• Quorum sensing inhibitors: a bargain of effects.

  2006cites this paper
• Interference of Lactobacillus plantarum with Pseudomonas aeruginosa in vitro and in infected burns: the potential use of probiotics in wound treatment.

  2005cites this paper
• Pseudomonas aeruginosa: Basic Research

  2005cites this paper
• In Situ Monitoring of Bacterial Presence and Activity

  2005cites this paper
• Airway Biofilms

  2005cites this paper
• Novel Mouse Model of Chronic Pseudomonas aeruginosa Lung Infection Mimicking Cystic Fibrosis

  2005cites this paper
• Use of a Whole-Cell Biosensor and Flow Cytometry to Detect AHL Production by an Indigenous Soil Community During Decomposition of Litter

  2005cites this paper