Preimplantation genetic diagnosis of numerical and structural chromosome abnormalities.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Reproductive Biomedicine Online

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S1472-6483(10)61938-4PMID 12470583
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Spectral karyotyping of fresh, non-inseminated oocytes.

  2002cited by this paper
• Aneuploidy in human oocytes: nondisjunction or predivision?

  2002cited by this paper
• Chromosome mosaicism in cleavage-stage human embryos: evidence of a maternal age effect.

  2002cited by this paper
• Predictive value of sperm chromosome analysis on the outcome of PGD for translocations.

  2001cited by this paper
• Clinical outcome of treatment cycles using preimplantation genetic diagnosis for structural chromosomal abnormalities

  2001cited by this paper
• Preimplantation genetic diagnosis of pericentric inversions

  2001cited by this paper
• Attitudes towards reproductive issues and carrier testing among adult patients and parents of children with cystic fibrosis (CF)

  2001cited by this paper
• Developmental ability of chromosomally abnormal human embryos to develop to the blastocyst stage.

  2001cited by this paper
• Textbook of Assisted Reproductive Techniques: Laboratory and Clinical Perspectives

  2001cited by this paper
• An improved fixation technique for fluorescence in situ hybridization for preimplantation genetic diagnosis.

  2001cited by this paper
• Outcome of preimplantation genetic diagnosis of translocations.

  2000cited by this paper
• Chromosome analysis of blastomeres from human embryos by using comparative genomic hybridization

  2000cited by this paper
• Mechanisms of maternal aneuploidy: FISH analysis of oocytes and polar bodies in patients undergoing assisted conception

  2000cited by this paper
• Healthy births and ongoing pregnancies obtained by preimplantation genetic diagnosis in patients with advanced maternal age and recurrent implantation failure.

  2000cited by this paper
• Mitochondrial DNA point mutation in human oocytes is associated with maternal age.

  2000cited by this paper
• Comprehensive chromosomal analysis of human preimplantation embryos using whole genome amplification and single cell comparative genomic hybridization.

  2000cited by this paper
• Female gamete segregation in two carriers of translocations involving 2q and 14q

  2000cited by this paper
• Chromosome abnormalities in 1255 cleavage-stage human embryos.

  2000cited by this paper
• Gamete segregation in female carriers of Robertsonian translocations

  2000cited by this paper
• Improvements of preimplantation diagnosis of aneuploidy by using microwave hybridization, cell recycling and monocolour labelling of probes.

  2000cited by this paper
• Effect of chromosomal translocations on the development of preimplantation human embryos in vitro.

  2000cited by this paper
• Assessing the Chromosome Copy Number in Metaphase II Oocytes by Sequential Fluorescence in Situ Hybridization

  2000cited by this paper
• Spectral Karyotyping of Unfertilized and Noninseminated Oocytes

  2000cited by this paper
• Analysis of chromosome abnormalities in sperm and embryos from two 45,XY,t(13;14)(q10;q10) carriers

  2000cited by this paper
• Patient-Specific Probes for Preimplantation Genetic Diagnosis of Structural and Numerical Aberrations in Interphase Cells

  1999cited by this paper
• Karyotyping of human oocytes by chromosomal analysis of the second polar bodies.

  1999cited by this paper
• Preimplantation genetic diagnosis and sperm analysis by fluorescence in-situ hybridization for the most common reciprocal translocation t(11;22).

  1999cited by this paper
• Rapid visualization of metaphase chromosomes in single human blastomeres after fusion with in-vitro matured bovine eggs.

  1999cited by this paper
• Prevention of Age-Related Aneuploidies by Polar Body Testing of Oocytes

  1999cited by this paper
• Detailed chromosomal and molecular genetic analysis of single cells by whole genome amplification and comparative genomic hybridisation.

  1999cited by this paper
• Chromosome translocations in couples with in-vitro fertilization implantation failure.

  1999cited by this paper
• Preimplantation diagnosis for aneuploidies in patients undergoing in vitro fertilization with a poor prognosis: identification of the categories for which it should be proposed.

  1999cited by this paper
• Advantages of Day 4 Embryo Transfer in Patients Undergoing Preimplantation Genetic Diagnosis of Aneuploidy

  1999cited by this paper
• A longitudinal study of pregnancy outcome following idiopathic recurrent miscarriage.

  1999cited by this paper
• Positive outcome after preimplantation diagnosis of aneuploidy in human embryos.

  1999cited by this paper
• In vitro fertilization plus preimplantation genetic diagnosis in patients with recurrent miscarriage: an analysis of chromosome abnormalities in human preimplantation embryos.

  1999cited by this paper
• Non-disjunction of chromosome 18.

  1998cited by this paper
• Increased frequency of congenital chromosomal aberrations in female partners of couples undergoing intracytoplasmic sperm injection.

  1998cited by this paper
• Chromosome studies in first polar bodies from hamster and human oocytes.

  1998cited by this paper
• First pregnancies after preconception diagnosis of translocations of maternal origin.

  1998cited by this paper
• Scoring criteria for preimplantation genetic diagnosis of numerical abnormalities for chromosomes X, Y, 13, 16, 18 and 21.

  1998cited by this paper
• Chromosome abnormalities in 447 couples undergoing intracytoplasmic sperm injection--prevalence, types, sex distribution and reproductive relevance.

  1998cited by this paper
• Preimplantation genetic diagnosis of chromosome balance in embryos from a patient with a balanced reciprocal translocation.

  1998cited by this paper
• Ooplasmic transfer in mature human oocytes.

  1998cited by this paper
• Chromosome abnormalities in human embryos.

  1998cited by this paper
• Mosaicism in the inner cell mass of human blastocysts.

  1998influential reference
• Spontaneous Abortions Are Reduced After Preconception Diagnosis of Translocations

  1998cited by this paper
• Preimplantation genetic analysis of translocations: case-specific probes for interphase cell analysis

  1998cited by this paper
• Case report: chromatid exchange and predivision of chromatids as other sources of abnormal oocytes detected by preimplantation genetic diagnosis of translocations

  1998cited by this paper
• Chromosome abnormalities in embryos obtained after conventional in vitro fertilization and intracytoplasmic sperm injection.

  1998cited by this paper
• Preimplantation diagnosis of the aneuploidies most commonly found in spontaneous abortions and live births: XY, 13, 14, 15, 16, 18, 21, 22

  1998cited by this paper
• Potential use of repeated fluorescence in situ hybridization in the same human blastomeres for preimplantation genetic diagnosis.

  1998cited by this paper
• Successful outcome with day 4 embryo transfer after preimplantation diagnosis for genetically transmitted diseases.

  1998cited by this paper
• Preimplantation genetic diagnosis of a large pericentric inversion of chromosome 5.

  1998cited by this paper
• Assessment of diagnostic quantitative fluorescent multiplex polymerase chain reaction assays performed on single cells

  1998cited by this paper
• FISH Preimplantation Diagnosis of Chromosome Aneuploidy in Recurrent Pregnancy Wastage

  1998cited by this paper
• Infertile couples with Robertsonian translocations: preimplantation genetic analysis of embryos reveals chaotic cleavage divisions

  1998cited by this paper
• Preimplantation genetic diagnosis of DiGeorge syndrome.

  1998cited by this paper
• Chromosome identification in human oocytes and polar bodies by spectral karyotyping

  1998cited by this paper
• Preimplantation Diagnosis of Common Aneuploidies by the First- and Second-Polar Body FISH Analysis

  1998cited by this paper
• Increased chromosome abnormalities in human preimplantation embryos after in-vitro fertilization in patients with recurrent miscarriage.

  1998cited by this paper
• Analysis of unfertilized oocytes subjected to intracytoplasmic sperm injection using two rounds of fluorescence in-situ hybridization and probes to five chromosomes.

  1997cited by this paper
• Prepregnancy Genetic Testing for Age-Related Aneuploidies by Polar Body Analysis

  1997cited by this paper
• First-meiotic-division nondisjunction in human oocytes.

  1997cited by this paper
• Preimplantation genetic diagnosis increases the implantation rate in human in vitro fertilization by avoiding the transfer of chromosomally abnormal embryos.

  1997cited by this paper
• Embryo selection by IVF, co-culture and transfer at the blastocyst stage in case of translocation.

  1997cited by this paper
• Carrier-specific breakpoint-spanning DNA probes: an approach to preimplantation genetic diagnosis in interphase cells.

  1997cited by this paper
• Multicolor Spectral Karyotyping of Human Chromosomes

  1996cited by this paper
• Maternal Uniparental Isodisomy of Human Chromosome 14 Associated with a Paternal t(13q14q) and Precocious Puberty

  1996cited by this paper
• Susceptible chiasmate configurations of chromosome 21 predispose to non–disjunction in both maternal meiosis I and meiosis II

  1996cited by this paper
• Aneuploidy 16 in human embryos increases significantly with maternal age.

  1996cited by this paper
• Preimplantation diagnosis of common aneuploidies in infertile couples of advanced maternal age.

  1996cited by this paper
• Association between nondisjunction and maternal age in meiosis-II human oocytes.

  1996cited by this paper
• Frequency of factors associated with habitual abortion in 197 couples.

  1996cited by this paper
• Molecular studies of translocations and trisomy involving chromosome 13.

  1996cited by this paper
• Reduction in signal overlap results in increased FISH efficiency: Implications for preimplantation genetic diagnosis

  1996cited by this paper
• Intracytoplasmic sperm injection in infertile patients with structural chromosome abnormalities.

  1996cited by this paper
• Simultaneous enumeration of chromosomes 13, 18, 21, X, and Y in interphase cells for preimplantation genetic diagnosis of aneuploidy.

  1996influential reference
• Birth of healthy children after preimplantation diagnosis of common aneuploidies by polar body fluorescent in situ hybridization analysis. Preimplantation Genetics Group.

  1996cited by this paper
• Maternal age effect on early human embryonic development and blastocyst formation

  1996cited by this paper
• Undocumented embryos: do not trash them, FISH them.

  1996cited by this paper
• Segregation analysis of four translocations, t(2;18), t(3;15), t(5;7), and t(10;12), by sperm chromosome studies and a review of the literature.

  1995cited by this paper
• Diagnosing and preventing inherited disease: Pregnancies following pre-conception diagnosis of common aneuploidies by fluorescent in-situ hybridization

  1995cited by this paper
• Mitochondrial deoxyribonucleic acid deletions in oocytes and reproductive aging in women.

  1995cited by this paper
• Paracentric inversions in humans: a review of 446 paracentric inversions with presentation of 120 new cases.

  1995cited by this paper
• Comparative Genomic Hybridization

  1995cited by this paper
• The use of first polar bodies for preimplantation diagnosis of aneuploidy.

  1995cited by this paper
• Trisomy 18: studies of the parent and cell division of origin and the effect of aberrant recombination on nondisjunction.

  1995cited by this paper
• Evaluation of cytogenetic analysis for clinical preimplantation diagnosis.

  1995cited by this paper
• Embryo morphology, developmental rates, and maternal age are correlated with chromosome abnormalities.

  1995cited by this paper
• Pregnancies following pre-conception diagnosis of common aneuploidies by fluorescent in-situ hybridization.

  1995cited by this paper
• The coelomic cavity: An important site of materno‐fetal nutrient exchange in the first trimester of pregnancy

  1994cited by this paper
• Monospermic polyploidy and atypical embryo morphology.

  1994cited by this paper
• Age-related decline in female fertility is not due to diminished capacity of the uterus to sustain embryo implantation.

  1994cited by this paper
• Non-disjunction of chromosome 21 in maternal meiosis I: evidence for a maternal age-dependent mechanism involving reduced recombination.

  1994cited by this paper
• Chromosome abnormalities in human arrested preimplantation embryos: a multiple-probe FISH study.

  1994cited by this paper
• Identification of the sex of human preimplantation embryos in two hours using an improved spreading method and fluorescent in-situ hybridization (FISH) using directly labelled probes.

  1994cited by this paper
• Early amniocentesis—a cytogenetic evaluation of over 1500 cases

  1994cited by this paper
• Female reproductive aging--ovarian and uterine factors

  1993cited by this paper
• Female reproductive aging — Ovarian and uterine factors

  1993cited by this paper

• The mosaic embryo: what it means for the doctor and the patient.

  2023cites this paper
• A novel approach toward the generation of oocytes by direct diploid cell haploidization.

  2023cites this paper
• IVF as a mirror of evolution

  2022cites this paper
• A review of pre-implantation genetic testing technologies and applications

  2022cites this paper
• Clinical outcomes following preimplantation genetic testing and microdissecting junction region in couples with balanced chromosome rearrangement

  2021cites this paper
• Evolution and Utility of Preimplantation Genetic Testing for Monogenic Disorders in Assisted Reproduction - A Narrative Review

  2021cites this paper
• Preimplantation Genetic Testing

  2021cites this paper
• Preimplantation Genetic Testing: A Review of Past and Current

  2021cites this paper
• Practical Preimplantation Genetic Testing

  2020cites this paper
• Genetic mutations contributing to non-obstructive azoospermia.

  2020cites this paper
• Origin of Aneuploidy and Strategies Underlying Clinical Application of Preimplantation Genetic Testing for Chromosomal Disorders (PGT-A and PGT-SR)

  2020cites this paper
• Chromosome Aneuploid Spectrum Evolving along with Development -Relates with Gene Content in Specific Chromosome

  2020cites this paper
• Motives and considerations regarding PGT in couples carrying a structural chromosomal abnormality: a qualitative exploration

  2020cites this paper
• Major Components of Preimplantation Genetic Testing

  2020cites this paper
• Quality of Blastocysts Created by Embryo Splitting: A Time-Lapse Monitoring and Chromosomal Aneuploidy Study

  2019cites this paper
• Interchromosomal effect in carriers of translocations and inversions assessed by preimplantation genetic testing for structural rearrangements (PGT-SR)

  2019cites this paper
• Chemically induced aneuploidy in germ cells. Part II of the report of the 2017 IWGT workgroup on assessing the risk of aneugens for carcinogenesis and hereditary diseases.

  2019cites this paper
• Chromosomal Heteromorphism with Reference to Cancer and Reproduction in Human: An Appraisal

  2019cites this paper
• The Progress of Next Generation Sequencing in Preimplantation Genetic Testing

  2018cites this paper
• Advances in preimplantation genetic testing with next generation sequencing

  2018cites this paper
• Preimplantation genetic testing for complex chromosomal rearrangement carriers by next-generation sequencing.

  2018cites this paper
• Chromosomal scan of single sperm cells by combining fluorescence-activated cell sorting and next-generation sequencing

  2018cites this paper
• Preimplantation Genetic Diagnosis and Screening

  2018cites this paper
• Tips and Tricks in Fluorescence In-situ Hybridization (FISH)- based Preimplantation Genetic Diagnosis /Screening (PGD/PGS)

  2018cites this paper
• Determining individual chromosome missegregation rates and the responses to aneuploidy in human cells

  2018cites this paper
• Preimplantation genetic testing: current challenges and future prospects

  2017cites this paper
• Genetic diseases and aneuploidies can be detected with a single blastocyst biopsy: a successful clinical approach

  2017influential citation
• Pre‐implantation genetic screening among women experiencing recurrent failure of in vitro fertilization

  2017cites this paper
• Genetic Analysis of Human Preimplantation Embryos.

  2016cites this paper
• The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring

  2016cites this paper
• ADN lliure en plasma matern: marcadors d’ADN fetal i detecció d’anomalies cromosòmiques d’origen patern

  2016cites this paper
• Healthy Baby Born to a Robertsonian Translocation Carrier following Next-Generation Sequencing-Based Preimplantation Genetic Diagnosis: A Case Report

  2015cites this paper
• First Successful Pregnancy After Pre-implantation Genetic Diagnosis by FISH for an Inversion Together with a Cryptic Translocation in India

  2015cites this paper
• Impact of blastocyst biopsy and comprehensive chromosome screening technology on preimplantation genetic screening: a systematic review of randomized controlled trials.

  2015cites this paper
• Validation of a semiconductor next‐generation sequencing‐based protocol for preimplantation genetic diagnosis of reciprocal translocations

  2015cites this paper
• Small Supernumerary Marker Chromosomes in Human Infertility

  2015cites this paper
• Influence of sperm fertilising concentration, sperm selection method and sperm capacitation procedure on the incidence of numerical chromosomal abnormalities in IVF early bovine embryos.

  2015cites this paper
• Recurrent miscarriage in translocation carriers: no differences in clinical characteristics between couples who accept and couples who decline PGD.

  2015cites this paper
• Correction: Increasing Live Birth Rate by Preimplantation Genetic Screening of Pooled Polar Bodies Using Array Comparative Genomic Hybridization

  2015cites this paper
• Array-Comparative-Genomic-Hybridization (Acgh) Based Preimplantation-Genetic-Diagnosis (PGD) for Balanced Translocation Carriers Improves both Diagnostic and Pregnancy Rates Compared to Fluorescent-In-Situ-Hybridization (FISH) and Polymerase-Chain-Reaction (PCR) Based PGD

  2015cites this paper
• Pregnancy outcomes following 24-chromosome preimplantation genetic diagnosis in couples with balanced reciprocal or Robertsonian translocations.

  2015cites this paper
• Biochemical and cytogenetic changes in postovulatory and in vitro aged mammalian oocytes: a predisposition to aneuploidy

  2015cites this paper
• Increasing Live Birth Rate by Preimplantation Genetic Screening of Pooled Polar Bodies Using Array Comparative Genomic Hybridization

  2015cites this paper
• Comparison between fluorescent in-situ hybridisation and array comparative genomic hybridisation in preimplantation genetic diagnosis in translocation carriers.

  2014cites this paper
• Preimplantation diagnosis for aneuploidies

  2014cites this paper
• New perspectives on preimplantation genetic diagnosis and preimplantation genetic screening.

  2014cites this paper
• Preimplantation diagnosis for translocations

  2014cites this paper
• A Cytogenetic Study of Couples with Miscarriages: An Experience from Manipal Referral Centre

  2013cites this paper
• A Case with Double Translocation and Sjögren's Syndrome

  2013cites this paper
• Safety, Accuracy and Reproductive Outcome of Preimplantation Genetic Diagnosis

  2013cites this paper
• Benefits and drawbacks of preimplantation genetic diagnosis (PGD) for reciprocal translocations: lessons from a prospective cohort study

  2013cites this paper
• Chromosome Segregation Analysis in Human Embryos Obtained from Couples Involving Male Carriers of Reciprocal or Robertsonian Translocation

  2012cites this paper
• Molecular Genetic Analysis of Single Cells

  2012cites this paper
• Approaches to Preimplantation Diagnosis

  2012cites this paper
• Clinical Outcome of Preimplantation Genetic Diagnosis

  2012cites this paper
• Cytogenetic in vivo assays in somatic cells.

  2012cites this paper
• Preimplantation Diagnosis for Chromosomal Disorders

  2012cites this paper
• Molecular Genetic Analysis of Single Cells Fiorentino 269

  2012cites this paper
• Bioinformatic Tools Identify Chromosome-Specific DNA Probes and Facilitate Risk Assessment by Detecting Aneusomies in Extra-embryonic Tissues

  2012cites this paper
• Extended culture up to the blastocyst stage: a strategy to avoid multiple pregnancies in assisted reproductive technologies.

  2011cites this paper
• PGD for reciprocal and Robertsonian translocations using array comparative genomic hybridization.

  2011cites this paper
• Meiotic segregation of Robertsonian translocations ascertained in cleavage-stage embryos--implications for preimplantation genetic diagnosis.

  2011cites this paper
• CHROMOSOME PAINTING AND ITS VERSATILITY IN MODERN DIAGNOSTICS

  2011cites this paper
• 14 Preimplantation genetic diagnosis in assisted reproduction: medical, ethical, and legal aspects

  2011cites this paper
• Reproductive genetics PGD for reciprocal and Robertsonian translocations using array comparative genomic hybridization

  2011cites this paper
• ESHRE PGD consortium best practice guidelines for fluorescence in situ hybridization-based PGD.

  2011cites this paper
• Conversion and non-conversion approach to preimplantation diagnosis for chromosomal rearrangements in 475 cycles.

  2010cites this paper
• Advances in understanding the genetic causes and mechanisms of female germ cell aneuploidy

  2010cites this paper
• Rapid mapping of chromosomal breakpoints: from blood to BAC in 20 days.

  2010influential citation
• Integrating Preimplantation Genetic Diagnosis into the ART Laboratory

  2010cites this paper
• Sperm FISH analysis in two healthy infertile brothers with t(15;18) unbalanced translocation: Implications for genetic counselling and reproductive management.

  2010cites this paper
• Miniaturization of molecular biological techniques for gene assay.

  2010cites this paper
• Preimplantation genetic diagnosis (PGD) for extremes--successful birth after PGD for a consanguineous couple carrying an identical balanced reciprocal translocation.

  2010cites this paper
• Molecular characterization of pluripotency in embryos and embryonic stem cells

  2010cites this paper
• Preimplantation genetic diagnosis (PGD) improves pregnancy outcome for translocation carriers with a history of recurrent losses.

  2010cites this paper
• A molecular strategy for routine preimplantation genetic diagnosis in both reciprocal and Robertsonian translocation carriers.

  2010cites this paper
• Polymerase chain reaction-based detection of chromosomal imbalances on embryos: the evolution of preimplantation genetic diagnosis for chromosomal translocations.

  2010cites this paper
• The role of assisted reproductive technology in the management of recurrent pregnancy loss

  2009cites this paper
• DNA Probe Pooling for Rapid Delineation of Chromosomal Breakpoints

  2009cites this paper
• Meiotic segregation of X-autosome translocation in two carriers and implications for assisted reproduction.

  2009cites this paper
• Sperm and embryo analysis in a carrier of supernumerary inv dup(15) marker chromosome.

  2009influential citation
• Diagnòstic genètic preimplantacional de malalties hereditàries fibrosi quística i hemofília

  2009cites this paper
• Impact of meiotic and mitotic non-disjunction on generation of human embryonic stem cell lines.

  2009cites this paper
• DNA Probe Pooling for Rapid Delineation of Chromosomal Breakpoints

  2009cites this paper
• Preimplantation genetic diagnosis: technological advances to improve accuracy and range of applications.

  2008cites this paper
• Derivation of Euploid Human Embryonic Stem Cells from Aneuploid Embryos

  2008cites this paper
• Preimplantation genetic diagnosis for complex chromosome rearrangements

  2008cites this paper
• Factors affecting the outcome of IVF/ICSI

  2008cites this paper
• Vitrification of preimplantation genetically diagnosed human blastocysts and its contribution to the cumulative ongoing pregnancy rate per cycle by using a closed device.

  2008cites this paper
• Estimation of chromosomal imbalances in preimplantation embryos from preimplantation genetic diagnosis cycles of reciprocal translocations with or without acrocentric chromosomes.

  2008cites this paper
• Application of genetic technology: a genuine step towards improving IVF standards

  2008cites this paper
• Clinical application of polar body biopsy

  2008cites this paper
• A healthy live birth after successful preimplantation genetic diagnosis for carriers of complex chromosome rearrangements.

  2008cites this paper
• Expanding and Improving the Service for Testing Single Embryonic Cells by Preimplantation Genetic Haplotyping

  2007cites this paper
• Duplication of the sperm genome by human androgenetic embryo production: towards testing the paternal genome prior to fertilization.

  2007cites this paper
• Preimplantation genetic diagnosis for monogenic diseases: overview and emerging issues

  2007cites this paper
• Assisted hatching is more effective when embryo quality was optimal in previous failed IVF/ICSI cycles

  2007cites this paper
• Gender determination and detection of aneuploidy in single cells using DNA array-based comparative genomic hybridization.

  2007cites this paper
• Polar body chromosome abnormalities and their consequences for human embryo development

  2007cites this paper
• Future genetic and other technologies for assessing embryos

  2007cites this paper