High-affinity multivalent DNA binding by using low-molecular-weight dendrons.

M. Kostiainen,J. Hardy,David K. Smith

Published 2005 in Angewandte Chemie

ABSTRACT

Nine spermines are better than one: Compound G2 exhibits high-affinity, salt-independent DNA binding as a consequence of the spermine array on its surface. Comparison with smaller dendrons and model compounds indicates a clear multivalency effect on binding.

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