Aspirin plus dipyridamole versus aspirin alone after cerebral ischaemia of arterial origin (ESPRIT): randomised controlled trial.

No abstract is available for this paper.

• Publication year

  2006

• Venue

  The Lancet

• Publication date

  2006-05-20

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0140-6736(06)68734-5PMID 16714187
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2006cited by this paper
• Clopidogrel and aspirin versus aspirin alone for the prevention of atherothrombotic events.

  2006cited by this paper
• Antiplatelet Drugs In the Secondary Prevention After Stroke: Differential Efficacy in Large Versus Small Vessel Disease? A Subgroup Analysis From ESPS-2

  2006cited by this paper
• Classification of Cause of Death After Stroke in Clinical Research

  2006cited by this paper
• Dipyridamole Bioavailability in Subjects With Reduced Gastric Acidity

  2005cited by this paper
• Population based study of early risk of stroke after transient ischaemic attack or minor stroke: implications for public education and organisation of services

  2004cited by this paper
• Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study).

  2004cited by this paper
• Dipyridamole and headache--a pilot study of initial dose titration.

  2004cited by this paper
• Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial.

  2004cited by this paper
• Secondary Prevention of Stroke

  2004cited by this paper
• Cochrane Review: Dipyridamole for Preventing Major Vascular Events in Patients With Vascular Disease

  2003cited by this paper
• Long-term prognosis after lacunar infarction.

  2003cited by this paper
• Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients

  2002cited by this paper
• Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients

  2002cited by this paper
• ESPRIT: protocol change.

  2001cited by this paper
• ESPRIT: Protocol Change

  2001cited by this paper
• Design of ESPRIT: An International Randomized Trial for Secondary Prevention after Non-Disabling Cerebral Ischaemia of Arterial Origin

  2000cited by this paper
• Design of ESPRIT: An International Randomized Trial for Secondary Prevention after Non-Disabling Cerebral Ischaemia of Arterial Origin

  2000cited by this paper
• SECONDARY PREVENTION AFTER CEREBRAL ISCHAEMIA OF PRESUMED ARTERIAL ORIGIN : IS ASPIRIN STILL THE TOUCHSTONE? AUTHORS' REPLY

  1999cited by this paper
• Cumulative meta-analysis of aspirin efficacy after cerebral ischaemia of arterial origin

  1999cited by this paper
• Secondary prevention after cerebral ischaemia of presumed arterial origin: is aspirin still the touchstone?

  1999cited by this paper
• European stroke prevention study 2: Efficacy and safety data

  1997cited by this paper
• Aspirin at any dose above 30 mg offers only modest protection after cerebral ischaemia.

  1996cited by this paper
• A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)

  1996cited by this paper
• European Stroke Prevention Study. 2. Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke.

  1996cited by this paper
• A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering Committee.

  1996cited by this paper
• Recurrent stroke after transient ischaemic attack or minor ischaemic stroke: does the distinction between small and large vessel disease remain true to type? Dutch TIA Trial Study Group.

  1995cited by this paper
• Science unblinded.

  1994cited by this paper
• Secondary prevention of stroke.

  1992cited by this paper
• Interobserver agreement for the assessment of handicap in stroke patients.

  1989cited by this paper
• Interobserver agreement for the assessment of handicap in stroke patients.

  1988cited by this paper
• Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group.

  1985cited by this paper
• Persantine Aspirin Trial in cerebral ischemia. Part II: Endpoint results. The American-Canadian Co-Operative Study group.

  1985cited by this paper
• "AICLA" controlled trial of aspirin and dipyridamole in the secondary prevention of athero-thrombotic cerebral ischemia.

  1983cited by this paper
• [Prevention of recurrences of cerebral ischemic vascular accidents by platelet antiaggregants. Results of a 3-year controlled therapeutic trial].

  1982cited by this paper
• A multiple testing procedure for clinical trials.

  1979cited by this paper

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  2026cites this paper
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  2026cites this paper
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  2026cites this paper
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  2026cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
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  2025cites this paper
• Antiplatelet drugs

  2025cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024cites this paper
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  2024influential citation
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  2024cites this paper
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  2024cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2023cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2022cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021influential citation
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2021cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020influential citation
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper