Analysis of codon:anticodon interactions within the ribosome provides new insights into codon reading and the genetic code structure.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  RNA: A publication of the RNA Society

• Publication date

  2001-07-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1017/S135583820100214XPMID 11453067PMCID PMC1370147
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Codon context

  2005cited by this paper
• Recognition of Cognate Transfer RNA by the 30S Ribosomal Subunit

  2001cited by this paper
• Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics

  2000cited by this paper
• Conformational switch in the decoding region of 16S rRNA during aminoacyl-tRNA selection on the ribosome

  2000cited by this paper
• The crystal structure of human eukaryotic release factor eRF1--mechanism of stop codon recognition and peptidyl-tRNA hydrolysis.

  2000cited by this paper
• A detailed view of a ribosomal active site: the structure of the L11-RNA complex.

  1999cited by this paper
• Codon reading patterns in Drosophila melanogaster mitochondria based on their tRNA sequences: a unique wobble rule in animal mitochondria.

  1999cited by this paper
• X-ray crystal structures of 70S ribosome functional complexes.

  1999cited by this paper
• Recognition of the codon-anticodon helix by ribosomal RNA.

  1999cited by this paper
• Crystal structure of a conserved ribosomal protein-RNA complex.

  1999cited by this paper
• Major groove binding of the tRNA/mRNA complex to the 16 S ribosomal RNA decoding site.

  1999cited by this paper
• Modified Nucleosides in Translation

  1998influential reference
• Complete kinetic mechanism of elongation factor Tu‐dependent binding of aminoacyl‐tRNA to the A site of the E.coli ribosome

  1998cited by this paper
• Mutual orientation of tRNAs and interactions between the codon-anticodon duplexes within the ribosome: a stereochemical analysis.

  1998cited by this paper
• Ribosomal tRNA binding sites: three-site models of translation.

  1998cited by this paper
• Mutual orientation of tRNAs and interactions between the codon-anticodon duplexes within the ribosome: a stereochemical analysis.

  1998cited by this paper
• The Methyl Group of theN6-Methyl-N6-Threonylcarbamoyladenosine in tRNA of Escherichia coli Modestly Improves the Efficiency of the tRNA

  1998cited by this paper
• Analysis of interactions between the codon-anticodon duplexes within the ribosome: their role in translation.

  1997cited by this paper
• Three modified nucleosides present in the anticodon stem and loop influence the in vivo aa-tRNA selection in a tRNA-dependent manner.

  1997cited by this paper
• High-level misincorporation of lysine for arginine at AGA codons in a fusion protein expressed in Escherichia coli.

  1996cited by this paper
• Structure of a U.U pair within a conserved ribosomal RNA hairpin.

  1996cited by this paper
• Ribosomal Decoding Processes at Codons in the A or P Sites Depend Differently on 2′-OH Groups (*)

  1995cited by this paper
• Structure of an RNA double helix including uracil-uracil base pairs in an internal loop

  1995cited by this paper
• Analysis of action of the wobble adenine on codon reading within the ribosome.

  1995influential reference
• The methylthio group (ms2) of N6-(4-hydroxyisopentenyl)-2-methylthioadenosine (ms2io6A) present next to the anticodon contributes to the decoding efficiency of the tRNA

  1995cited by this paper
• Translation of synonymous codons in family boxes by Mycoplasma capricolum tRNAs with unmodified uridine or adenosine at the first anticodon position.

  1995cited by this paper
• Decoding with the A:I wobble pair is inefficient.

  1995influential reference
• Structure of a mispaired RNA double helix at 1.6-A resolution and implications for the prediction of RNA secondary structure.

  1994cited by this paper
• Analysis of action of wobble nucleoside modifications on codon-anticodon pairing within the ribosome.

  1994influential reference
• Solution of the ribosome riddle: how the ribosome selects the correct aminoacyl‐tRNA out of 41 similar contestants

  1993influential reference
• Undiscriminating codon reading with adenosine in the wobble position.

  1993cited by this paper
• Recent evidence for evolution of the genetic code

  1992cited by this paper
• Codon—anticodon pairing A model for interacting codon—anticodon duplexes located at the ribosomal A‐ and P‐sites

  1992influential reference
• Proofreading, NTPases and translation: constraints on accurate biochemistry.

  1992cited by this paper
• Crystal structure of an RNA double helix incorporating a track of non-Watson–Crick base pairs

  1991cited by this paper
• Wobble position modified nucleosides evolved to select transfer RNA codon recognition: a modified-wobble hypothesis.

  1991cited by this paper
• Chapter 7 Codon Recognition: Evaluation of the Effects of Modified Bases in the Anticodon Loop of Trna Using the Temperature-Jump Relaxation Method

  1990cited by this paper
• Intermediate states in the movement of transfer RNA in the ribosome

  1989cited by this paper
• Errors and alternatives in reading the universal genetic code.

  1989cited by this paper
• tRNA-tRNA interactions within cellular ribosomes.

  1989cited by this paper
• Actions of the anticodon arm in translation on the phenotypes of RNA mutants.

  1986cited by this paper
• Molecular mechanism of codon recognition by tRNA species with modified uridine in the first position of the anticodon.

  1985cited by this paper
• Sense codons are found in specific contexts.

  1985cited by this paper
• Hydrogen bonding in nucleosides and nucleotides

  1985cited by this paper
• Comparison of ribosomal entry and acceptor transfer ribonucleic acid binding sites on Escherichia coli 70S ribosomes. Fluorescence energy transfer measurements from Phe-tRNAPhe to the 3' end of 16S ribonucleic acid.

  1983cited by this paper
• Principles of Nucleic Acid Structure

  1983cited by this paper
• The accuracy of protein biosynthesis is limited by its speed: high fidelity selection by ribosomes of aminoacyl-tRNA ternary complexes containing GTP[gamma S].

  1982cited by this paper
• Translational efficiency of transfer RNA's: uses of an extended anticodon.

  1982cited by this paper
• In vivo decoding rules in Schizosaccharomyces pombe are at variance with in vitro data

  1981cited by this paper
• Crystal structure of yeast tRNAAsp

  1980cited by this paper
• On the physical basis for ambiguity in genetic coding interactions.

  1978cited by this paper
• Physical Chemistry: Principles and Applications in Biological Sciences

  1978cited by this paper
• Aminoacyl-tRNA binding at the recognition site is the first step of the elongation cycle of protein synthesis.

  1977cited by this paper
• Kinetic amplification of enzyme discrimination.

  1975cited by this paper
• Kinetic proofreading: a new mechanism for reducing errors in biosynthetic processes requiring high specificity.

  1974cited by this paper
• Conformation of polypeptides and proteins.

  1968cited by this paper
• Codon--anticodon pairing: the wobble hypothesis.

  1966influential reference

• Codon decoding by split-tRNA: revisiting the tRNA selection mechanism

  2025cites this paper
• Variation in the fitness impact of translationally optimal codons among animals

  2024cites this paper
• The central role of transfer RNAs in mistranslation

  2024influential citation
• Impact of queuosine modification of endogenous E. coli tRNAs on sense codon reassignment

  2022cites this paper
• Enhanced Codon-Anticodon Interaction at In-Frame UAG Stop Codon Improves the Efficiency of Non-Natural Amino Acid Mutagenesis.

  2022cites this paper
• Formation and persistence of polyglutamine aggregates in mistranslating cells

  2021cites this paper
• The “guiding” principles of noncoding RNA function

  2021cites this paper
• Translational Control by Ribosome Pausing in Bacteria: How a Non-uniform Pace of Translation Affects Protein Production and Folding

  2021cites this paper
• Alteration in H-bond strength affects the stability of codon-anticodon interaction at in-frame UAG stop codon during in vitro translation

  2021cites this paper
• Naturally occurring modified ribonucleosides

  2020cites this paper
• Genome-wide Survey of Ribosome Collision.

  2020cites this paper
• tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast

  2020influential citation
• Signal Transduction in Ribosome Biogenesis: A Recipe to Avoid Disaster

  2019cites this paper
• The emerging impact of tRNA modifications in the brain and nervous system.

  2019cites this paper
• Above the Epitranscriptome: RNA Modifications and Stem Cell Identity

  2018influential citation
• The Contribution of Purifying Selection, Linkage, and Mutation Bias to the Negative Correlation between Gene Expression and Polymorphism Density in Yeast Populations

  2018cites this paper
• Structure, fonction et évolution de la famille universelle Sua5/YrdC impliquée dans la synthèse du nucléoside modifié t6A

  2017cites this paper
• Chemical and structural effects of base modifications in messenger RNA

  2017cites this paper
• Decoding options and accuracy of translation of developmentally regulated UUA codon in Streptomyces: bioinformatic analysis

  2016influential citation
• Forced Ambiguity of the Leucine Codons for Multiple-Site-Specific Incorporation of a Noncanonical Amino Acid

  2016cites this paper
• Codon-Anticodon Recognition in the Bacillus subtilis glyQS T Box Riboswitch

  2015cites this paper
• Estimating Gene Expression and Codon-Specific Translational Efficiencies, Mutation Biases, and Selection Coefficients from Genomic Data Alone‡

  2015cites this paper
• Improved ribosome-footprint and mRNA measurements provide insights into dynamics and regulation of yeast translation

  2015cites this paper
• The influence of hypermodified nucleosides lysidine and t(6)A to recognize the AUA codon instead of AUG: a molecular dynamics simulation study.

  2015cites this paper
• Transfer RNA Modification: Presence, Synthesis, and Function

  2014cites this paper
• Modelling the Efficiency of Codon–tRNA Interactions Based on Codon Usage Bias

  2014cites this paper
• Crystal basis model: Codon-Anticodon interaction and genetic code evolution

  2014cites this paper
• Crystal basis model: Codon-Anticodon interaction and genetic code evolution

  2014cites this paper
• Estimating gene expression and codon specific translational efficiencies, mutation biases, and selection coefficients from genomic data alone

  2014cites this paper
• Atom-Specific Modification of Uracil Bases with Selenium for RNA Structure and Function Studies

  2014cites this paper
• A‐to‐I editing on tRNAs: Biochemical, biological and evolutionary implications

  2014cites this paper
• An Ode to the Code: Evidence for Fine-Tuning in the Standard Codon Table

  2013cites this paper
• DOMAIN 4 SYNTHESIS AND PROCESSING OF MACROMOLECULES Transfer RNA Modification

  2013cites this paper
• Mutation in ADAT3, encoding adenosine deaminase acting on transfer RNA, causes intellectual disability and strabismus

  2013cites this paper
• 2-Selenouridine triphosphate synthesis and Se-RNA transcription

  2013cites this paper
• Rate-Limiting Steps in Yeast Protein Translation

  2013cites this paper
• Molecular Dynamics Simulations of the Ribosome

  2012cites this paper
• 9.5 Dynamics of Very Large Systems: The Ribosome

  2012cites this paper
• Explaining complex codon usage patterns with selection for translational efficiency, mutation bias, and genetic drift

  2011influential citation
• On the evolution of codon usage bias

  2011influential citation
• A minimum principle in codon-anticodon interaction

  2011cites this paper
• Q8IYL2 is a candidate gene for the familial epilepsy syndrome of Partial Epilepsy with Pericentral Spikes (PEPS).

  2011cites this paper
• Evidence that the supE44 Mutation of Escherichia coli Is an Amber Suppressor Allele of glnX and that It Also Suppresses Ochre and Opal Nonsense Mutations

  2010cites this paper
• Effect of Correlated tRNA Abundances on Translation Errors and Evolution of Codon Usage Bias

  2010cites this paper
• Tetracycline, Aminoglycoside, Macrolide, and Miscellaneous Antibiotics

  2010cites this paper
• Stochastic gating and drug-ribosome interactions.

  2009cites this paper
• The fourfold way of the genetic code

  2009cites this paper
• Unconventional decoding of the AUA codon as methionine by mitochondrial tRNAMet with the anticodon f5CAU as revealed with a mitochondrial in vitro translation system

  2009cites this paper
• The role of upstream sequences in selecting the reading frame on tmRNA

  2008cites this paper
• Codon usage in mitochondrial genomes: distinguishing context-dependent mutation from translational selection.

  2008cites this paper
• Transcriptional slippage prompts recoding in alternate reading frames in the hepatitis C virus (HCV) core sequence from strain HCV-1.

  2008cites this paper
• Anticodon loop mutations perturb reading frame maintenance by the E site tRNA.

  2008cites this paper
• tRNA's wobble decoding of the genome: 40 years of modification.

  2007cites this paper
• Performance of the Translational Apparatus Varies with the Ecological Strategies of Bacteria

  2007cites this paper
• Testing constraints on rRNA bases that make nonsequence-specific contacts with the codon-anticodon complex in the ribosomal A site.

  2007cites this paper
• Etudes structurales de différents processus biologiques impliquant les ARN de transfert

  2007cites this paper
• specialization, and efficient decoding for translation optimization Codon usage bias from tRNA's point of view: Redundancy,

  2007cites this paper
• Evolution of codon usage in bacteria

  2007cites this paper
• Genetic analysis of the E site during RF2 programmed frameshifting.

  2007cites this paper
• The RNA polymerase III-dependent family of genes in hemiascomycetes: comparative RNomics, decoding strategies, transcription and evolutionary implications

  2006cites this paper
• Multiple stages in codon-anticodon recognition: double-trigger mechanisms and geometric constraints.

  2006cites this paper
• Classification of the possible pairs between the first anticodon and the third codon positions based on a simple model assuming two geometries with which the pairing effectively potentiates the decoding complex.

  2006cites this paper
• Kinetic, energetic, and stereochemical factors determining the molecular recognition of proteins and nucleic acids

  2006cites this paper
• tRNAGlu wobble uridine methylation by Trm9 identifies Elongator's key role for zymocin‐induced cell death in yeast

  2006cites this paper
• Ribosome Builder: A software project to simulate the ribosome

  2005cites this paper
• Ribosomal elongation cycle: energetic, kinetic and stereochemical aspects.

  2005cites this paper
• Analysis of recognition of transfer-messenger RNA by the ribosomal decoding center.

  2005cites this paper
• Simulating movement of tRNA into the ribosome during decoding.

  2005cites this paper
• The Crucial Role of Conserved Intermolecular H-bonds Inaccessible to the Solvent in Formation and Stabilization of the TL5·5 SrRNA Complex*

  2005cites this paper
• Modified nucleotides in tRNA(Lys) and tRNA(Val) are important for translocation.

  2004cites this paper
• Modified Nucleotides in tRNALys and tRNAVal are Important for Translocation

  2004cites this paper
• Codon usage bias from tRNA's point of view: redundancy, specialization, and efficient decoding for translation optimization.

  2004cites this paper
• The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAPro(cmo5UGG) promotes reading of all four proline codons in vivo.

  2004cites this paper
• Decoding the genome: a modified view.

  2004cites this paper
• The GTPase Activity and C-terminal Cysteine of the Escherichia coli MnmE Protein Are Essential for Its tRNA Modifying Function*

  2003cites this paper
• Unnatural RNA display libraries.

  2003cites this paper
• Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors.

  2003cites this paper
• SURVEY AND SUMMARY: Roles of 5-substituents of tRNA wobble uridines in the recognition of purine-ending codons

  2003cites this paper
• Understanding discrimination by the ribosome: stability testing and groove measurement of codon-anticodon pairs.

  2003cites this paper
• In vitro selection for sense codon suppression.

  2003cites this paper
• Novel Methyltransferase for Modified Uridine Residues at the Wobble Position of tRNA

  2003cites this paper
• How does tmRNA move through the ribosome?

  2002cites this paper
• tRNomics: analysis of tRNA genes from 50 genomes of Eukarya, Archaea, and Bacteria reveals anticodon-sparing strategies and domain-specific features.

  2002cites this paper
• Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome.

  2002cites this paper
• RNA editing by adenosine deaminases generates RNA and protein diversity.

  2002cites this paper
• Selection of tRNA by the ribosome requires a transition from an open to a closed form.

  2002cites this paper
• Accurate Translation of the Genetic Code Depends on tRNA Modified Nucleosides*

  2002cites this paper