Antimicrobial peptides, isolated from horseshoe crab hemocytes, tachyplesin II, and polyphemusins I and II: chemical structures and biological activity.

No abstract is available for this paper.

• Publication year

  1989

• Venue

  Journal of Biochemistry (Tokyo)

• Publication date

  1989-10-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1093/OXFORDJOURNALS.JBCHEM.A122913PMID 2514185
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Tachyplesin, a class of antimicrobial peptide from the hemocytes of the horseshoe crab (Tachypleus tridentatus). Isolation and chemical structure.

  1988cited by this paper
• Hemocytic and Humoral Immunity in Arthropods

  1987cited by this paper
• Primary structure of anti-lipopolysaccharide factor from American horseshoe crab, Limulus polyphemus.

  1987cited by this paper
• Lipopolysaccharide-sensitive serine-protease zymogen (factor C) of horseshoe crab hemocytes. Identification and alignment of proteolytic fragments produced during the activation show that it is a novel type of serine protease.

  1987cited by this paper
• Lipopolysaccharide-sensitive serine-protease zymogen (factor C) found in Limulus hemocytes. Isolation and characterization.

  1986cited by this paper
• Molecular cloning of a cDNA and assignment of the C-terminal of sarcotoxin IA, a potent antibacterial protein of Sarcophaga peregrina.

  1986cited by this paper
• Primary structure of limulus anticoagulant anti-lipopolysaccharide factor.

  1986cited by this paper
• Primary structure of sarcotoxin I, an antibacterial protein induced in the hemolymph of Sarcophaga peregrina (flesh fly) larvae.

  1985cited by this paper
• Isolation and biological activities of limulus anticoagulant (anti-LPS factor) which interacts with lipopolysaccharide (LPS).

  1985cited by this paper
• Verification of protein sequence by fast atom bombardment mass spectrometry. Amino acid sequence of protein S, a development-specific protein of Myxococcus xanthus.

  1984cited by this paper
• Anti‐LPS factor in the horseshoe crab, Tachypleus tridentatus

  1984cited by this paper
• Limulus anti-LPS factor: an anticoagulant which inhibits the endotoxin mediated activation of Limulus coagulation system.

  1982cited by this paper
• A lipopolysaccharide-binding cell-surface protein from Salmonella minnesota. Isolation, partial characterization and occurrence in different Enterobacteriaceae.

  1979cited by this paper
• PRODUCTION OF Vi ANTIGEN ON A CHEMICALLY DEFINED MEDIUM BY A COLIFORM BACTERIUM

  1960cited by this paper

• Marine-derived antimicrobial peptides (AMPs): Blue biotechnological assets for sustainable healthcare and circular bioeconomy.

  2026cites this paper
• Antimicrobial Peptides From Diversified Biological Resources Unveiling Platforms as Therapeutic Scaffold Against the Superbugs—A Review

  2026cites this paper
• β-Hairpin Antimicrobial Peptides: Class Diversity and Sequence Analysis.

  2026cites this paper
• Aquatic Invertebrate Antimicrobial Peptides in the Fight Against Aquaculture Pathogens

  2025cites this paper
• Unlocking Antimicrobial Peptides: In Silico Proteolysis and Artificial Intelligence-Driven Discovery from Cnidarian Omics

  2025cites this paper
• Peptides in Chronic Wound Healing: Fighting Infections and Facilitating Diabetic Wound Management

  2025cites this paper
• Activation of the Coagulation Cascade as a Universal Danger Sign

  2025cites this paper
• Advances in the discovery, mechanism of action, optimization of activity and potential for clinical application of antimicrobial peptides

  2025cites this paper
• Development strategies and application of antimicrobial peptides as future alternatives to in-feed antibiotics.

  2024cites this paper
• Antifungal peptides from living organisms

  2024cites this paper
• Antimicrobial resistance crisis: could artificial intelligence be the solution?

  2024cites this paper
• Antimicrobial peptides as new antibiotics: A comprehensive review

  2024cites this paper
• Antimicrobial Peptide Synergies for Fighting Infectious Diseases

  2023cites this paper
• Adapting antibacterial display to identify serum active macrocyclic peptide antibiotics

  2023cites this paper
• Antimicrobial peptides from marine animals: Sources, structures, mechanisms and the potential for drug development

  2023cites this paper
• Marine Invertebrate Antimicrobial Peptides and Their Potential as Novel Peptide Antibiotics

  2023cites this paper
• Molecular identification of a novel antimicrobial peptide in giant Triton snail Charonia tritonis: mRNA profiles for tissues and its potential antibacterial activity.

  2023cites this paper
• Adapting antibacterial display to identify serum-active macrocyclic peptide antibiotics

  2023cites this paper
• Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure–Activity Relationships to Therapeutic Applications

  2023cites this paper
• Development of a Novel Peptide with Antimicrobial and Mineralising Properties for Caries Management

  2023cites this paper
• Host Defense Proteins and Peptides with Lipopolysaccharide-Binding Activity from Marine Invertebrates and Their Therapeutic Potential in Gram-Negative Sepsis

  2023cites this paper
• Antimicrobial Peptides with Anti-Candida Activity

  2022cites this paper
• Antimicrobial peptides: On future antiprotozoal and anthelminthic applications.

  2022cites this paper
• Expression strategies for the efficient synthesis of antimicrobial peptides in plastids

  2022cites this paper
• Proteomic analysis of Malaysian Horseshoe crab (Tachypleus gigas) hemocytes gives insights into its innate immunity host defence system and other biological processes

  2022cites this paper
• Biomolecules of the Horseshoe Crab’s Hemolymph: Components of an Ancient Defensive Mechanism and Its Impact on the Pharmaceutical and Biomedical Industry

  2022cites this paper
• Tachyplesin and CyLoP-1 as efficient anti-mycobacterial peptides: A novel finding.

  2022cites this paper
• Current development of bicyclic peptides

  2022cites this paper
• Tachyplesin I and its derivatives: A pharmaco-chemical perspective on their antimicrobial and antitumor potential

  2022cites this paper
• Synthetic Analogs of Antimicrobial Peptides from Limulus Inhibit the Growth of Listeria monocytogenes by Increasing Cell Membrane Permeability and Suppressing Virulence Genes

  2022cites this paper
• Marine Arthropods as a Source of Antimicrobial Peptides

  2022cites this paper
• Synthetic Analogs of Antimicrobial Peptides from Limulus Inhibit the Growth of Listeria monocytogenes by Increasing Cell Membrane Permeability and Suppressing Virulence Genes

  2022cites this paper
• Der Chemokinrezeptor CXCR4 – seine Entwicklung und Bedeutung in der nuklearmedizinischen Theranostik

  2021cites this paper
• Antibacterial Activity of T22, a Specific Peptidic Ligand of the Tumoral Marker CXCR4

  2021cites this paper
• Marine Invertebrate Peptides: Antimicrobial Peptides

  2021cites this paper
• In vivo immunostimulatory effect of the amoebocyte lysate and plasma of Asian horseshoe crab, Tachypleus gigas in a piscine model

  2021cites this paper
• Antimicrobial Peptides: A New Hope in Biomedical and Pharmaceutical Fields

  2021cites this paper
• Systematical Screening of Intracellular Protein Targets of Polyphemusin-I Using Escherichia coli Proteome Microarrays

  2021influential citation
• Revealing the mode of action of halictine antimicrobial peptides: a comprehensive study with model membranes.

  2020cites this paper
• The unusual conformation of cross‐strand disulfide bonds is critical to the stability of β‐hairpin peptides

  2020cites this paper
• EXPLORATORY STUDIES INTO THE THERAPEUTIC AND DIAGNOSTIC CAPABILITY OF BLOOD FROM THE HORSESHOE CRAB , LIMULUS POLYPHEMUS by Whitney

  2020cites this paper
• Supramolecular Peptide Assemblies as Antimicrobial Scaffolds

  2020cites this paper
• Hemolymph Proteomics and Gut Microbiota of Horseshoe Crabs Tachypleus tridentatus and Carcinoscorpius rotundicauda

  2020cites this paper
• Potential role of the antimicrobial peptide Tachyplesin III against multidrug-resistant P. aeruginosa and A. baumannii coinfection in an animal model

  2019cites this paper
• The Vast Structural Diversity of Antimicrobial Peptides.

  2019cites this paper
• Expression of recombinant tachyplesin I in Pichia pastoris.

  2019cites this paper
• Antimicrobial peptides: new hope in the war against multidrug resistance

  2019cites this paper
• The draft genome of horseshoe crab Tachypleus tridentatus reveals its evolutionary scenario and well-developed innate immunity

  2019cites this paper
• effects of yeast antimicrobial peptide in aquaculture

  2019cites this paper
• Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties

  2019cites this paper
• Modulation of Human Complement System by Antimicrobial Peptide Arenicin-1 from Arenicola marina

  2018cites this paper
• Identification of a novel antimicrobial peptide from the sea star Patiria pectinifera

  2018cites this paper
• Peptides: Production, bioactivity, functionality, and applications

  2018cites this paper
• Conformational-Restricted Cyclic Peptides

  2018cites this paper
• The Remarkable Cationic Peptides: A Boon to Pharmaceutical Sciences?

  2018cites this paper
• Identification of Peptides Implicated in Antibacterial Activity of Snow Crab Hepatopancreas Hydrolysates by a Bioassay-Guided Fractionation Approach Combined with Mass Spectrometry

  2018cites this paper
• The Biological and Biophysical Properties of the Spider Peptide Gomesin

  2018cites this paper
• Isolation and Purification of antibacterial proteins from hemolymph of Marine gastropods dwelling at rocky shores of Kanyakumari, Southeast coast of India

  2018cites this paper
• Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III

  2018cites this paper
• Antimicrobial Peptides: Diversity, Mechanism of Action and Strategies to Improve the Activity and Biocompatibility In Vivo

  2018influential citation
• Influences of disulfide connectivity on structure and antimicrobial activity of tachyplesin I

  2018cites this paper
• Control of Aspergillus flavus growth and aflatoxin production in transgenic maize kernels expressing a tachyplesin-derived synthetic peptide, AGM182.

  2018cites this paper
• Tachyplesin Causes Membrane Instability That Kills Multidrug-Resistant Bacteria by Inhibiting the 3-Ketoacyl Carrier Protein Reductase FabG

  2018cites this paper
• Designing Antimicrobial Peptide: Current Status

  2017cites this paper
• Comparison of Cytotoxic Activity in Leukemic Lineages Reveals Important Features of β‐Hairpin Antimicrobial Peptides

  2017cites this paper
• 1-(2-aminophenyl)-1H-1,2,3-triazole-4-carboxylic acid: activity against Gram-positive and Gram-negative pathogens including Vibrio cholerae

  2017cites this paper
• Exploring the global animal biodiversity in the search for new drugs – Spiders, scorpions, horseshoe crabs, sea spiders, centipedes, and millipedes

  2017influential citation
• Eradication of Staphylococcus aureus Biofilm Infections Using Synthetic Antimicrobial Peptides

  2017cites this paper
• Structure-Activity and -Toxicity Relationships of the Antimicrobial Peptide Tachyplesin-1.

  2017cites this paper
• Antimicrobial peptides (AMPs): Ancient compounds that represent novel weapons in the fight against bacteria.

  2017cites this paper
• A Therapeutic Potential of Animal β-hairpin Antimicrobial Peptides.

  2017cites this paper
• Influence of chain length on the activity of tripeptidomimetic antagonists for CXC chemokine receptor 4 (CXCR4).

  2017cites this paper
• Improved strategy for recombinant production and purification of antimicrobial peptide tachyplesin I and its analogs with high cell selectivity

  2017cites this paper
• The role of natural antimicrobial peptides during infection and chronic inflammation

  2017cites this paper
• Elucidation of structural and functional integration of a novel antimicrobial peptide from Antheraea mylitta.

  2017cites this paper
• Screening and Purification of an Antimicrobial Peptide from the Gill of the Manila Clam Ruditapes philippinarum

  2016cites this paper
• Isolation and Purification of Antimicrobial Peptide from Hard-shelled Mussel, Mytilus coruscus

  2016cites this paper
• Mirror Images of Antimicrobial Peptides Provide Reflections on Their Functions and Amyloidogenic Properties.

  2016cites this paper
• Molecular imaging probes derived from natural peptides.

  2016cites this paper
• Immunity of the lugworm Arenicola marina: cells and molecules

  2016cites this paper
• A Review of Antifungal Peptides: Basis to New Era of Antifungal Drugs

  2016cites this paper
• Experimental Induction of Bacterial Resistance to the Antimicrobial Peptide Tachyplesin I and Investigation of the Resistance Mechanisms

  2016cites this paper
• Antiviral function of Tachyplesin I against iridovirus and nodavirus.

  2016cites this paper
• Marine Antimicrobial Peptides: Nature Provides Templates for the Design of Novel Compounds against Pathogenic Bacteria

  2016cites this paper
• Antimicrobial peptides of invertebrates. Part 1. structure, biosynthesis, and evolution

  2016cites this paper
• Antimicrobial activity of

  2016cites this paper
• Contribution of Amphipathicity and Hydrophobicity to the Antimicrobial Activity and Cytotoxicity of β-Hairpin Peptides

  2016cites this paper
• Antimicrobial activity of Tachyplesin 1 against Burkholderia pseudomallei: an in vitro and in silico approach

  2016influential citation
• Antimicrobial and antioxidant properties of the crude peptide extracts of Galatea paradoxa and Patella rustica

  2015cites this paper
• Peptides and Peptidomimetics for Antimicrobial Drug Design

  2015cites this paper
• Peptidomimetics of α‐Helical and β‐Strand Protein Binding Epitopes

  2015cites this paper
• Effects of tachyplesin I on the embryonic development of zebrafish

  2015cites this paper
• Positron Emission Tomographic Imaging of CXCR4 in Cancer: Challenges and Promises

  2015cites this paper
• Changing Global Perspectives on Horseshoe Crab Biology, Conservation and Management

  2015cites this paper
• Role of Marine Natural Products in the Genesis of Antiviral Agents.

  2015cites this paper
• Horseshoe Crabs in Modern Day Biotechnological Applications

  2015cites this paper
• The Intricate Role of CXCR 4 in Cancer

  2015cites this paper
• Structure and Biological Functions of β-Hairpin Antimicrobial Peptides

  2015cites this paper
• Prospection, Collection, and Preservation of Marine Samples

  2014cites this paper
• Biological Activities of Acidic Extracts of the Starfish Asterina pectinifera

  2014cites this paper