Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Cancer Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11782386
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Protein Kinase SGK Mediates Survival Signals by Phosphorylating the Forkhead Transcription Factor FKHRL1 (FOXO3a)

  2001cited by this paper
• Alcohol and aldehyde dehydrogenase gene polymorphisms and oropharyngolaryngeal, esophageal and stomach cancers in Japanese alcoholics.

  2001cited by this paper
• Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer.

  2001cited by this paper
• Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas

  2001cited by this paper
• Loss of cyclin D2 expression in the majority of breast cancers is associated with promoter hypermethylation.

  2001cited by this paper
• Genetic analysis of early- versus late-stage ovarian tumors.

  2001cited by this paper
• Genomic structure and promoter characterization of an imprinted tumor suppressor gene ARHI.

  2001cited by this paper
• Identification of homozygous deletions at chromosome 16q23 in Aflatoxin B1 exposed hepatocellular carcinoma

  2001cited by this paper
• Loss of expression of a new member of the DNAJ protein family confers resistance to chemotherapeutic agents used in the treatment of ovarian cancer.

  2001cited by this paper
• The histone deacetylase-3 complex contains nuclear receptor corepressors.

  2000cited by this paper
• Significance of multiple mutations in cancer.

  2000cited by this paper
• Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary.

  2000cited by this paper
• A frequent deletion polymorphism on chromosome 22q13 identified by representational difference analysis of ovarian cancer.

  2000cited by this paper
• Rapid upregulation of serum and glucocorticoid-regulated kinase (sgk) gene expression by corticosteroids in vivo.

  2000cited by this paper
• Expression of calcium-binding protein S100A2 in breast lesions

  2000cited by this paper
• DNA methylation: past, present and future directions.

  2000cited by this paper
• Elevated Egr-1 in Human Atherosclerotic Cells Transcriptionally Represses the Transforming Growth Factor-β Type II Receptor*

  2000influential reference
• Identification of iron responsive genes by screening cDNA libraries from suppression subtractive hybridization with antisense probes from three iron conditions.

  2000cited by this paper
• Exon sharing of a novel human zinc-finger gene, ZIM2, and paternally expressed gene 3 (PEG3).

  2000influential reference
• Downmodulation of caveolin-1 expression in human ovarian carcinoma is directly related to α-folate receptor overexpression

  2000cited by this paper
• Performance on the Wisconsin Card Sorting Test Among Adolescents in Taiwan: Norms, Factorial Structure, and Relation to Schizotypy

  2000cited by this paper
• Identification and characterization of a homozygous deletion found in ovarian ascites by representational difference analysis.

  1999cited by this paper
• Cancer-epigenetics comes of age

  1999cited by this paper
• Isolation of a novel gene, TSP50, by a hypomethylated DNA fragment in human breast cancer.

  1999cited by this paper
• Itm2a Is Induced during Thymocyte Selection and T Cell Activation and Causes Downregulation of Cd8 When Overexpressed in Cd4+Cd8+ Double Positive Thymocytes

  1999cited by this paper
• Cancer statistics, 1999

  1999cited by this paper
• Frequent deletions within FRA7G at 7q31.2 in invasive epithelial ovarian cancer

  1999cited by this paper
• A novel region of deletion on chromosome 6q23.3 spanning less than 500 Kb in high grade invasive epithelial ovarian cancer

  1999cited by this paper
• Suppression subtractive hybridization: a versatile method for identifying differentially expressed genes.

  1999cited by this paper
• Involvement of H-cadherin (CDH13) on 16q in the region of frequent deletion in ovarian cancer.

  1999cited by this paper
• The diverse role of selenium within selenoproteins: a review.

  1999cited by this paper
• Protein targeting to glycogen/PPP1R5: screening of coding and flanking genomic regions for polymorphisms and association analysis with insulin action in Pima Indians.

  1999cited by this paper
• Overexpression of multisubunit replication factors in yeast.

  1999cited by this paper
• Activation of SPARC expression in reactive stroma associated with human epithelial ovarian cancer.

  1999cited by this paper
• NOEY2 (ARHI), an imprinted putative tumor suppressor gene in ovarian and breast carcinomas.

  1999influential reference
• [20] Suppression subtractive hybridization: A versatile method for identifying differentially expressed genes

  1999cited by this paper
• Genes encoding human caveolin‐1 and ‐2 are co‐localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancers

  1998cited by this paper
• Loss of heterozygosity on chromosomes 7p, 7q, 9p and 11q is an early event in ovarian tumorigenesis

  1998cited by this paper
• Human CDC23: cDNA cloning, mapping to 5q31, genomic structure, and evaluation as a candidate tumor suppressor gene in myeloid leukemias.

  1998cited by this paper
• Duplication of two distinct regions on chromosome 5Q in non‐papillary renal‐cell carcinomas

  1998cited by this paper
• Genomic organization of the human SPOCK gene and its chromosomal localization to 5q31.

  1998cited by this paper
• Molecular analysis of new subtypes of ELE/RET rearrangements, their reciprocal transcripts and breakpoints in papillary thyroid carcinomas of children after Chernobyl

  1998cited by this paper
• Biological characterization of human epithelial ovarian carcinoma cells in primary culture: the insulin-like growth factor system.

  1998cited by this paper
• Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization

  1998influential reference
• Human HtrA, an Evolutionarily Conserved Serine Protease Identified as a Differentially Expressed Gene Product in Osteoarthritic Cartilage*

  1998cited by this paper
• FGF7 protein expression in human breast carcinomas

  1998cited by this paper
• Loss of heterozygosity in human ovarian cancer on chromosome 19q.

  1997cited by this paper
• DD/AP-PCR: combination of differential display and arbitrarily primed PCR of oligo(dT) cDNA.

  1997cited by this paper
• Molecular genetic analysis of TGF-beta1 in ovarian neoplasia.

  1997cited by this paper
• [The secretion and receptor gene of insulin-like growth factor-I quantitative expression in ovarian stroma in polycystic ovarian syndrome patients].

  1997cited by this paper
• Localization of the gene for a serine protease with IGF-binding domain (PRSS11) to human chromosome 10q25.3-q26.2.

  1997cited by this paper
• SPARC, an extracellular matrix protein with tumor-suppressing activity in human ovarian epithelial cells.

  1996cited by this paper
• Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries.

  1996cited by this paper
• Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase close to D1S514 and the centromeric D1Z5 locus

  1995influential reference
• Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase close to D1S514 and the centromeric D1Z5 locus.

  1995cited by this paper
• Structural characterization of the FKHR gene and its rearrangement in alveolar rhabdomyosarcoma.

  1995cited by this paper
• Expression of cyclin D2 in Epstein-Barr virus-positive Burkitt's lymphoma cell lines is related to methylation status of the gene

  1995cited by this paper
• Basic fibroblast growth factor and receptor expression in human ovarian cancer.

  1994cited by this paper
• Loss of heterozygosity on chromosome 5 in sporadic ovarian carcinoma is a late event and is not associated with mutations in APC at 5q21–22

  1994cited by this paper
• Human epithelial ovarian cancer allelotype.

  1993cited by this paper
• Transcription factor SIII: a novel component of the RNA polymerase II elongation complex.

  1993cited by this paper
• Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction.

  1992cited by this paper
• Complementary physical and genetic techniques map the vinculin (VCL) gene on chromosome 10q.

  1992cited by this paper
• Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction.

  1992cited by this paper
• Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases.

  1991cited by this paper
• Localization of human platelet proteoglycan gene to chromosome 10, band q22.1, by in situ hybridization

  1989cited by this paper
• Cancer statistics

  1989cited by this paper
• Nucleotide sequence of the cDNA coding for human complement C1r.

  1986cited by this paper
• Experimental model systems of ovarian cancer: applications to the design and evaluation of new treatment approaches.

  1984cited by this paper

• HTRA1 promotes EMT through the HDAC6/Ac‐α‐tubulin pathway in human GBM cells

  2024cites this paper
• High expression of SULF1 is associated with adverse prognosis in breast cancer brain metastasis

  2024cites this paper
• Current look at the most promising proteomic and glycomic biomarkers of bladder cancer

  2024cites this paper
• Proteomics Profiling of Bladder Cancer Tissues from Early to Advanced Stages Reveals NNMT and GALK1 as Biomarkers for Early Detection and Prognosis of BCa

  2023cites this paper
• Development of novel monoclonal antibodies and immunoassays for sensitive and specific detection of SULF1 endosulfatase.

  2020cites this paper
• Molecular structure and the role of high‐temperature requirement protein 1 in skeletal disorders and cancers

  2019cites this paper
• FAST TRACK GENE EXPRESSION PROFILES IN PRIMARY OVARIAN SEROUS PAPILLARY TUMORS AND NORMAL OVARIAN EPITHELIUM: IDENTIFICATION OF CANDIDATE MOLECULAR MARKERS FOR OVARIAN CANCER DIAGNOSIS AND THERAPY

  2018cites this paper
• HtrA1 expression and the prognosis of high-grade serous ovarian carcinoma: a cohort study using digital analysis

  2018cites this paper
• N-Terminomics identifies HtrA1 cleavage of thrombospondin-1 with generation of a proangiogenic fragment in the polarized retinal pigment epithelial cell model of age-related macular degeneration.

  2018cites this paper
• Functional analysis of genetic variants associated with age-related macular degeneration (AMD) - The HtrA serine peptidase 1 (HTRA1)

  2016cites this paper
• Synonymous variants in HTRA1 implicated in AMD susceptibility impair its capacity to regulate TGF-β signaling.

  2015cites this paper
• Analysis of Htra Gene from Zebrafish (Danio Rerio)

  2015cites this paper
• HtrA1 Gene and Functions

  2015cites this paper
• Statistical methods for the detection, analyses and integration of biomarkers in the human genome and transcriptome

  2014cites this paper
• Function and clinical relevance of kallikrein-related peptidases and other serine proteases in gynecological cancers

  2014cites this paper
• Cartilage tissue engineering: molecular control of chondrocyte differentiation for proper cartilage matrix reconstruction.

  2014cites this paper
• Expression and localization of serine protease Htra1 in neuroblastoma: correlation with cellular differentiation grade

  2014cites this paper
• Wnt/β-catenin pathway as a potential prognostic and predictive marker in patients with advanced ovarian cancer

  2014cites this paper
• HtrA3 Is Downregulated in Cancer Cell Lines and Significantly Reduced in Primary Serous and Granulosa Cell Ovarian Tumors

  2013cites this paper
• Decreased Expression of Transcription Elongation Factor A-Like 7 Is Associated with Gastric Adenocarcinoma Prognosis

  2013cites this paper
• HtrA1 in human urothelial bladder cancer: A secreted protein and a potential novel biomarker

  2013cites this paper
• Claudins Overexpression in Ovarian Cancer: Potential Targets for Clostridium Perfringens Enterotoxin (CPE) Based Diagnosis and Therapy

  2013cites this paper
• Detrimental Role for Human High Temperature Requirement Serine Protease A1 (HTRA1) in the Pathogenesis of Intervertebral Disc (IVD) Degeneration*

  2012cites this paper
• The enhanced antitumor effects of biodegradable cationic heparin-polyethyleneimine nanogels delivering HSulf-1 gene combined with cisplatin on ovarian cancer.

  2012cites this paper
• Molecular Adaptation of the DegQ Protease to Exert Protein Quality Control in the Bacterial Cell Envelope*

  2011cites this paper
• Heparin-Degrading Sulfatases in Hepatocellular Carcinoma: Potential roles in Pathogenesis and Identification of Therapeutic Targets

  2011cites this paper
• Decidual HtrA3 negatively regulates trophoblast invasion during human placentation.

  2011cites this paper
• The Pennsylvania State University The Graduate School Intercollege Graduate Degree Program in Genetics EXPRESSION AND FUNCTION OF THE TUMOR SUPPRESSOR CANDIDATE HTRA1 IN HUMAN BREAST EPITHELIAL CELLS

  2011cites this paper
• Early pregnancy Decidual HtrA 3 negatively regulates trophoblast invasion during human placentation

  2011cites this paper
• TCEAL7, a putative tumor suppressor gene, negatively regulates NF-κB pathway

  2010cites this paper
• Serine protease HtrA1 expression in human hepatocellular carcinoma.

  2010cites this paper
• Screening of genes related to ovary development in Chinese shrimp Fenneropenaeus chinensis by suppression subtractive hybridization.

  2010cites this paper
• Inhibition of HTRA3 stimulates trophoblast invasion during human placental development.

  2010cites this paper
• Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer

  2010cites this paper
• Expression profile of genes identified in human spermatogonial stem cell‐like cells using suppression subtractive hybridization

  2010cites this paper
• Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.

  2009cites this paper
• Aberrant promoter methylation and expression of the imprinted PEG3 gene in glioma

  2009cites this paper
• Die genetische und funktionelle Bedeutung des High Temperature Requirement A1 Proteins (HtrA1) und eines HtrA1-Single Nucleotide Polymorphismus für Morbus Alzheimer

  2009cites this paper
• Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer.

  2009cites this paper
• Molecular Genetics of Age-related Macular Degeneration

  2008cites this paper
• Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer.

  2008cites this paper
• Changes in expression of serine proteases HtrA1 and HtrA2 during estrogen-induced oxidative stress and nephrocarcinogenesis in male Syrian hamster.

  2008cites this paper
• Differential gene expression analysis of ovarian cancer in a population isolate.

  2008cites this paper
• The Tumor Suppressor Function of Human Sulfatase 1 (SULF1) in Carcinogenesis

  2008influential citation
• Heparin-degrading sulfatases in hepatocellular carcinoma: roles in pathogenesis and therapy targets.

  2008cites this paper
• Identification of Up-Regulated Genes in Malignant Glioma with Subtraction Hybridization: Preliminary Screening Studies

  2008cites this paper
• Sulfatase 2 up‐regulates glypican 3, promotes fibroblast growth factor signaling, and decreases survival in hepatocellular carcinoma

  2008cites this paper
• Imprinted tumor suppressor genes ARHI and PEG3 are the most frequently down‐regulated in human ovarian cancers by loss of heterozygosity and promoter methylation

  2008cites this paper
• The mitochondrial serine protease HtrA2/Omi: an overview

  2008cites this paper
• Gene Expression Arrays for Pathway Analysis in Cancer Research

  2008cites this paper
• A role for candidate tumor-suppressor gene TCEAL7 in the regulation of c-Myc activity, cyclin D1 levels and cellular transformation

  2008cites this paper
• Verfahren zur Analyse der epigenetischen Lage des HtrA1 Gens in einer biologischen Probe

  2008cites this paper
• Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings.

  2007cites this paper
• AWARD NUMBER: W81XWH-04-1-0085 TITLE: Functional Characterization of a Novel Pro-Apoptotic Transcription Regulatory Protein in Ovarian Cancer

  2007cites this paper
• The secreted serine protease xHtrA1 is a positive feedback regulator of long-range FGF signaling.

  2007cites this paper
• Molecular Markers in Epithelial Ovarian Cancer

  2007cites this paper
• Microarray Data Analysis

  2007cites this paper
• Progression-associated genes in astrocytoma identified by novel microarray gene expression data reanalysis.

  2007cites this paper
• Genetic intra‐tumour heterogeneity in epithelial ovarian cancer and its implications for molecular diagnosis of tumours

  2007cites this paper
• Genetic markers and biomarkers for age-related macular degeneration

  2007cites this paper
• Analysis of HtrA1 serine protease expression in human lung cancer.

  2006cites this paper
• Annexin-1 downregulation in thyroid cancer correlates to the degree of tumour differentiation

  2006cites this paper
• The Role of Human HtrA1 in Arthritic Disease*

  2006cites this paper
• Extracellular Matrix of Ovarian Tumors

  2006cites this paper
• Mutation and expression analysis of LZTS1 in ovarian cancer.

  2006cites this paper
• Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: identification of novel molecular biomarkers for early diagnosis and therapy.

  2006cites this paper
• Discovery of Differentially Overexpressed Genes in Immortalized Cells and Human Pulmonary Non-small Cell Carcinomas.

  2006cites this paper
• Incessant ovulation, inflammation and epithelial ovarian carcinogenesis: revisiting old hypotheses.

  2006cites this paper
• Piceatannol stimulates osteoblast differentiation that may be mediated by increased bone morphogenetic protein-2 production.

  2006cites this paper
• Extracellular matrix of ovarian tumors.

  2006cites this paper
• SULF1 inhibits tumor growth and potentiates the effects of histone deacetylase inhibitors in hepatocellular carcinoma.

  2006cites this paper
• Negative and Positive Regulation of Gene Expression by Mouse Histone Deacetylase1

  2006cites this paper
• Implications of the serine protease HtrA1 in amyloid precursor protein processing

  2005cites this paper
• The Relationship ofMolecularMarkers of p 53 Function and Angiogenesis to Prognosis of Stage IEpithelial Ovarian Cancer

  2005cites this paper
• Angiogenesis in normal and neoplastic ovaries

  2005cites this paper
• Treatment of chemotherapy-resistant human ovarian cancer xenografts in C.B-17/SCID mice by intraperitoneal administration of Clostridium perfringens enterotoxin.

  2005cites this paper
• Gene Expression Profiles of Serous , Endometrioid , and Clear Cell Subtypes ofOvarianand Endometrial Cancer

  2005cites this paper
• Biallelic methylation and silencing of paternally expressed gene 3 (PEG3) in gynecologic cancer cell lines.

  2005cites this paper
• Expression of S100P protein correlates with and contributes to the tumorigenic capacity of HeLa cervical carcinoma cells.

  2005cites this paper
• In silico chromosomal clustering of genes displaying altered expression patterns in ovarian cancer.

  2005cites this paper
• Gene Expression Profiles of Serous, Endometrioid, and Clear Cell Subtypes of Ovarian and Endometrial Cancer

  2005cites this paper
• The Relationship of Molecular Markers of p53 Function and Angiogenesis to Prognosis of Stage I Epithelial Ovarian Cancer

  2005cites this paper
• Functional Characterization of a Novel Pro-Apoptotic Transcriptional Regulatory Protein in Ovarian Cancer

  2005cites this paper
• [Genomic medicine. Polymorphisms and microarray applications].

  2004cites this paper
• Molecular and clinicopathological analysis of ovarian carcinomas with and without microsatellite instability.

  2004cites this paper
• Neurodegeneration Caused by Proteins with an Aberrant Carboxyl‐Terminus

  2004cites this paper
• Annexin A1 down-regulation in head and neck cancer is associated with epithelial differentiation status.

  2004cites this paper
• 6. Cathepsin K inhibitors: their potential as anti-osteoporosis agents.

  2004cites this paper
• Strategies for identifying genes that play a role in spinal cord regeneration

  2004cites this paper
• HtrA1 serine protease inhibits signaling mediated by Tgfβ family proteins

  2004cites this paper
• Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: Identification of candidate molecular markers for ovarian cancer diagnosis and therapy

  2004cites this paper
• Developmentally regulated expression of mouse HtrA3 and its role as an inhibitor of TGF‐β signaling

  2004cites this paper
• Cloning and identification of NS5ATP2 gene and its spliced variant transactivated by hepatitis C virus non-structural protein 5A.

  2004cites this paper
• Medicina genómica: Aplicaciones del polimorfismo de un nucleótido y micromatrices de ADN

  2004cites this paper
• Crystal structure of the DegS stress sensor: How a PDZ domain recognizes misfolded protein and activates a protease.

  2004cites this paper
• Binding of proteins to the PDZ domain regulates proteolytic activity of HtrA1 serine protease.

  2004cites this paper
• The Serine Protease HtrA1 Is Upregulated in the Human Placenta during Pregnancy

  2004cites this paper
• hSulf1 Sulfatase promotes apoptosis of hepatocellular cancer cells by decreasing heparin-binding growth factor signaling.

  2004cites this paper
• Cell membrane glycosylation mediates the adhesion, migration, and invasion of ovarian carcinoma cells

  2004cites this paper
• Pattern of Expression of HtrA1 During Mouse Development

  2004cites this paper