Control of the pericentrosomal H2O2 level by peroxiredoxin I is critical for mitotic progression

Reversible oxidative inactivation of centrosome-bound protein phosphatases such as Cdc14B by H2O2 is likely responsible for the inhibition of Cdk1-opposing phosphatases during early mitosis, which prevents premature degradation of mitotic activators.

• Publication year

  2015

• Venue

  Journal of Cell Biology

• Publication date

  2015-07-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1083/jcb.201412068PMID 26150388PMCID 4493999
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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