Molecular biology of prostate cancer

No abstract is available for this paper.

• Publication year

  2004

• Venue

  World journal of urology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1007/BF00184605PMID 8912472
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Mutations in the Androgen Receptor Gene Are Associated with Progression of Human Prostate Cancer to Androgen Independence I

  2008cited by this paper
• Molecular biology of prostate cancer.

  2003cited by this paper
• Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer

  1997cited by this paper
• Detection of c-myc oncogene amplification and chromosomal anomalies in metastatic prostatic carcinoma by fluorescence in situ hybridization.

  1997cited by this paper
• Location of KAI1 on the short arm of human chromosome 11 and frequency of allelic loss in advanced human prostate cancer

  1997cited by this paper
• Aberrant E-cadherin and alpha-catenin expression in prostate cancer: correlation with patient survival.

  1997cited by this paper
• Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.

  1997cited by this paper
• Combination of prostate-specific antigen, clinical stage, and Gleason score to predict pathological stage of localized prostate cancer. A multi-institutional update.

  1997cited by this paper
• A novel human prostate-specific, androgen-regulated homeobox gene (NKX3.1) that maps to 8p21, a region frequently deleted in prostate cancer.

  1997cited by this paper
• PTEN, a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

  1997cited by this paper
• CD44 is a metastasis suppressor gene for prostatic cancer located on human chromosome 11p13.

  1997cited by this paper
• Association of prostate cancer risk with genetic polymorphisms in vitamin D receptor and androgen receptor.

  1997cited by this paper
• Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor.

  1997cited by this paper
• Loss of heterozygosity at 16q24.1-q24.2 is significantly associated with metastatic and aggressive behavior of prostate cancer.

  1997cited by this paper
• Loss of heterozygosity at chromosome 16q in prostate adenocarcinoma: identification of three independent regions.

  1997cited by this paper
• Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells

  1996cited by this paper
• Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells.

  1996cited by this paper
• Increased bcl-2 protein levels in prostatic adenocarcinomas are not associated with rearrangements in the 2.8 kb major breakpoint region or with p53 protein accumulation.

  1996cited by this paper
• NM23 gene expression in human prostatic carcinomas and benign prostatic hyperplasias: altered expression in combined androgen blockaded carcinomas.

  1996cited by this paper
• Mutations in the androgen receptor gene are associated with progression of human prostate cancer to androgen independence.

  1996cited by this paper
• Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate.

  1996cited by this paper
• Androgen receptor content of prostate carcinoma cells estimated by immunohistochemistry is related to prognosis of patients with stage D2 prostate carcinoma

  1996cited by this paper
• Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

  1996cited by this paper
• Alterations of the retinoblastoma gene in human prostate adenocarcinoma

  1996cited by this paper
• Cancer statistics, 1996

  1996cited by this paper
• Down-regulation of the KAI1 metastasis suppressor gene during the progression of human prostatic cancer infrequently involves gene mutation or allelic loss.

  1996cited by this paper
• Alterations of the retinoblastoma gene in clinically localized, stage B prostate adenocarcinomas.

  1996cited by this paper
• Loss of expression of transforming growth factor beta type I and type II receptors correlates with tumor grade in human prostate cancer tissues.

  1996cited by this paper
• Expression of bcl-2 and the progression of human and rodent prostatic cancers.

  1996cited by this paper
• Genomic methylation patterns of the Dunning R-3327 prostate adenocarcinoma system.

  1996cited by this paper
• Expression of E-cadherin in primary and metastatic prostate cancer.

  1996cited by this paper
• Alteration of the tumor suppressor gene p53 in a high fraction of hormone refractory prostate cancer.

  1995cited by this paper
• Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer.

  1995cited by this paper
• Androgens induce resistance to bcl-2-mediated apoptosis in LNCaP prostate cancer cells.

  1995cited by this paper
• KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2.

  1995cited by this paper
• Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.

  1995cited by this paper
• c-met proto-oncogene expression in benign and malignant human prostate tissues.

  1995cited by this paper
• Allelic loss on chromosome 8p12-21 in microdissected prostatic intraepithelial neoplasia.

  1995cited by this paper
• Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancers

  1995cited by this paper
• Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

  1995cited by this paper
• p53 Mutations Occur in Clinical, but Not Latent, Human Prostate Carcinoma

  1995cited by this paper
• Mutational Analysis of CDKN2 (CDK4I/MTS1) Gene in Tissues and Cell Lines of Human Prostate Cancer

  1995cited by this paper
• Retinoblastoma gene mutations in primary human prostate cancer

  1995cited by this paper
• E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.

  1995cited by this paper
• Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.

  1995cited by this paper
• Somatic mutations of the WAF1/CIP1 gene in primary prostate cancer.

  1995cited by this paper
• Transforming growth factor-beta 1: comparative immunohistochemical localization in human primary and metastatic prostate cancer.

  1995cited by this paper
• Localization of potential tumor suppressor loci to a < 2 Mb region on chromosome 17q in human prostate cancer.

  1995cited by this paper
• TP53 mutations in prostatic cancer. Analysis of pre‐ and post‐treatment archival formalin‐fixed tumour tissue

  1995cited by this paper
• Prevalence of androgen receptor gene mutations in latent prostatic carcinomas from Japanese men.

  1995cited by this paper
• Frequency and characterization of p53 mutations in clinically localized prostate cancer.

  1995cited by this paper
• Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

  1995cited by this paper
• Heterogeneity in intratumor distribution of p53 mutations in human prostate cancer.

  1995cited by this paper
• The frequency of apoptosis correlates with the prognosis of gleason grade 3 adenocarcinoma of the prostate

  1995cited by this paper
• Molecular biology of prostate cancer progression.

  1995cited by this paper
• Immunohistochemical detection of p53 protein as a prognostic indicator in prostate cancer.

  1995cited by this paper
• Endocrine control of prostate cancer.

  1995cited by this paper
• Homozygous deletions at 8p22 and 8p21 in prostate cancer implicate these regions as the sites for candidate tumor suppressor genes.

  1995cited by this paper
• Association of p53 mutations with metastatic prostate cancer.

  1995cited by this paper
• Hereditary aspects of prostate cancer.

  1995cited by this paper
• Apoptosis and the prostate.

  1995cited by this paper
• Allelic loss of the retinoblastoma gene in primary human prostatic adenocarcinomas

  1995cited by this paper
• Frequent loss of heterozygosity at 7q31.1 in primary prostate cancer is associated with tumor aggressiveness and progression.

  1995cited by this paper
• Transforming growth factor beta 2 (TGF-beta 2) levels in plasma of patients with metastatic breast cancer treated with tamoxifen.

  1995cited by this paper
• Mutation of the MXI1 gene in prostate cancer

  1995cited by this paper
• Genetic alterations in prostate adenocarcinoma.

  1995cited by this paper
• Different tumor types from BRCA2 carriers show wild-type chromosome deletions on 13q12-q13.

  1995cited by this paper
• Transforming Growth Factor β2 (TGF-β2) Levels in Plasma of Patients with Metastatic Breast Cancer Treated with Tamoxifen

  1995cited by this paper
• Tumor suppressor gene P53 mutations in human prostate cancer

  1995cited by this paper
• In vivo amplification of the androgen receptor gene and progression of human prostate cancer

  1995cited by this paper
• Loss of the retinoblastoma susceptibility gene (RB1) is a frequent and early event in prostatic tumorigenesis.

  1994cited by this paper
• Genetic alterations in localized prostate cancer: Identification of a common region of deletion on chromosome arm 18q

  1994influential reference
• Induction of transforming growth factor beta in hormonally treated human prostate cancer.

  1994cited by this paper
• P53 mutations and loss of heterozygosity on chromosomes 8p, 16q, 17p, and 18q are confined to advanced prostate cancer.

  1994cited by this paper
• Bcl-2 and the regulation of programmed cell death

  1994cited by this paper
• Allelic loss in locally metastatic, multisampled prostate cancer.

  1994cited by this paper
• Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1.

  1994cited by this paper
• Quantitation of NM23 expression in human prostate tissues.

  1994cited by this paper
• Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis.

  1994cited by this paper
• Immunohistochemical determination of p53 protein nuclear accumulation in prostatic adenocarcinoma.

  1994cited by this paper
• Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance

  1994cited by this paper
• Molecular and cellular changes associated with the acquisition of metastatic ability by prostatic cancer cells

  1994cited by this paper
• Role of mesenchymal‐epithelial interactions in normal and abnormal development of the mammary gland and prostate

  1994cited by this paper
• Steroid-growth factor interaction in human prostate cancer. 1. Short-term effects of transforming growth factors on growth of human prostate cancer cells.

  1994cited by this paper
• Androgen receptor status in localized and locally progressive hormone refractory human prostate cancer.

  1994cited by this paper
• Genetic alterations in prostate cancer.

  1994cited by this paper
• Expression of transforming growth factor-alpha and the epidermal growth factor receptor in human prostate tissues.

  1994cited by this paper
• p53 in prostate cancer: frequent expressed transition mutations.

  1994cited by this paper
• Molecular biology of prostate cancer.

  1994cited by this paper
• High levels of nm23 expression are related to cell proliferation in human prostate cancer.

  1994cited by this paper
• Transcriptional regulation of the human E-cadherin gene in human prostate cancer cell lines: characterization of the human E-cadherin gene promoter.

  1994cited by this paper
• p53 oncogene mutations in human prostate cancer specimens.

  1994cited by this paper
• Frequent detection of codon 877 mutation in the androgen receptor gene in advanced prostate cancers.

  1994cited by this paper
• Basic research in prostate cancer: molecular biology.

  1994cited by this paper
• WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis.

  1994cited by this paper
• Tumor suppressor genes in prostatic oncogenesis.

  1994cited by this paper
• Partial growth suppression of human prostate cancer cells by the Krev‐1 suppressor gene

  1994cited by this paper
• Molecular biologic aspects of human prostatic carcinoma.

  1994influential reference
• Frequency and characterization of p53 mutations in primary and metastatic human prostate cancer

  1994cited by this paper
• Basic research in prostate cancer: molecular biology.

  1994cited by this paper

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• Molecular genetic, diagnosis, prevention and gene therapy in prostatic cancer: review article

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• Ficus deltoidea leaves methanol extract promote wound healing activity in mice

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• Proteostasis and Disease: From Basic Mechanisms to Clinics

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• Molecular genetic, diagnosis, prevention and gene therapy in prostatic cancer: review article

  2020cites this paper
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  2019cites this paper
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  2018cites this paper
• Molecular alterations associated with prostate cancer

  2018cites this paper
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  2017cites this paper
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• ANDROGEN-REGULATED GENE EXPRESSED IN PROSTATE TISSUE

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• Expressions of genes encoding steroidogenic enzymes and their role in prostate carcinogenesis

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• The prostate cancer immunome: In silico functional analysis of antigenic proteins from microarray profiling with IgG

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  2014cites this paper
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  2013cites this paper
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• DNA methylation profile during multistage progression of pulmonary adenocarcinomas

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• Characterization of ultrasound elevation beamwidth artifacts for prostate brachytherapy needle insertion.

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• Immunohistochemical analysis of Hedgehog signaling in prostatic adenocarcinoma

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• Tissue changes in senescent gerbil prostate after hormone deprivation leads to acquisition of androgen insensitivity

  2010cites this paper
• Chemopreventive potential of curcumin in prostate cancer

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• Cancer Biomarker Discovery: The Entropic Hallmark

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• Engineered antibody and neuropeptide mediated radionuclide targeting in prostate cancer

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• Eradication of therapy-resistant human prostate tumors using an ultrasound-guided site-specific cancer terminator virus delivery approach.

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• The Mechanism of Androgen Deprivation and the Androgen Receptor

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• Chinese medicinal herb Scutellaria barbata modulates apoptosis and cell survival in murine and human prostate cancer cells and tumor development in TRAMP mice

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• Lack of BRAF Activating Mutations in Prostate Adenocarcinoma: A Study of 93 Cases

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• MOLECULAR GENETIC, DIAGNOSIS, PREVENTION AND GENE THERAPY IN PROSTATIC CANCER: REVIEW ARTICLE

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• Angiotensin-converting enzyme insertion/deletion and angiotensin type 1 receptor A1166C polymorphisms as genetic risk factors in benign prostatic hyperplasia and prostate cancer

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• Association of the AA genotype of the BCL2 (-938C>A) promoter polymorphism with better survival in ovarian cancer.

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• Inhibition of breast and prostate cancer cell growth by 3,3'-diindolylmethane and related compounds

  2009influential citation
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  2009cites this paper
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  2008cites this paper
• Targeting the androgen receptor pathway in prostate cancer.

  2008cites this paper
• BASIC SCIENCE REVIEW

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• Relevance of a new rat model of osteoblastic metastases from prostate carcinoma for preclinical studies using zoledronic acid

  2008cites this paper
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  2007cites this paper
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  2007cites this paper
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  2007influential citation
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  2007cites this paper
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  2006cites this paper
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  2006cites this paper
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