Endothelin‐3 Regulates Endothelin‐1 Production in Cultured Human Endothelial Cells

No abstract is available for this paper.

• Publication year

  1991

• Venue

  HYPERTENSION

• Publication date

  1991-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/01.HYP.18.3.304PMID 1653767
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Endothelin and eicosanoid synthesis in cultured mesangial cells.

  1990cited by this paper
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  1990influential reference
• Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways.

  1989cited by this paper
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  1989cited by this paper
• Prolonged blood pressure elevation after endothelin administration in bilaterally nephrectomized rats.

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• Secretory mechanism of immunoreactive endothelin in cultured bovine endothelial cells.

  1989cited by this paper
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  1989influential reference
• Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat.

  1989cited by this paper
• Effect of calcium on endothelium-derived relaxing factor formation and cGMP levels in endothelial cells.

  1989influential reference
• Endothelin action: Inhibition by a protein kinase C inhibitor and involvement of phosphoinositols.

  1989cited by this paper
• Endothelin stimulates the release of prostacyclin from rat mesenteric arteries.

  1989cited by this paper
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• The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes.

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  1989cited by this paper
• Acute effects of endothelin on renal hemodynamics and blood pressure in anesthetized rats.

  1989cited by this paper
• A specific inhibitor of nitric oxide formation from l‐arginine attenuates endothelium‐dependent relaxation

  1989cited by this paper
• The Human Preproendothelin‐1 Gene: Possible Regulation by Endothelial Phosphoinositide Turnover Signaling

  1989influential reference
• Two different forms of endothelin receptors in rat lung

  1989cited by this paper
• Identification of arginine as a precursor of endothelium-derived relaxing factor.

  1988cited by this paper
• Inositol phosphate production and Ca2+ mobilization in human umbilical-vein endothelial cells stimulated by thrombin and histamine.

  1988cited by this paper
• A novel potent vasoconstrictor peptide produced by vascular endothelial cells

  1988cited by this paper
• Vascular endothelial cells synthesize nitric oxide from L-arginine

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• Endothelium‐derived relaxing factor and atriopeptin II elevate cyclic GMP levels in pig aortic endothelial cells

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• Endothelin stimulates phospholipase C in cultured vascular smooth muscle cells.

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• Forskolin and prostacyclin inhibit fluoride induced platelet activation and protein kinase C dependent responses.

  1988cited by this paper
• Molecular mechanism of action of the vasoconstrictor peptide endothelin.

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• Measurement of intracellular calcium concentration in intact monolayers of human endothelial cells.

  1988cited by this paper
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• Stimulation of cell growth and inhibition of prostacyclin production by heparin in human umbilical vein endothelial cells

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• Thrombin-stimulated elevation of human endothelial-cell cytoplasmic free calcium concentration causes prostacyclin production.

  1988influential reference
• Sarafotoxin, a novel vasoconstrictor peptide: phosphoinositide hydrolysis in rat heart and brain.

  1988cited by this paper
• The influence of basic residues on the substrate specificity of protein kinase C.

  1987cited by this paper
• Renal prostaglandins and phospholipase A2 in spontaneously hypertensive rats.

  1987cited by this paper
• Single‐channel recordings of three types of calcium channels in chick sensory neurones.

  1987cited by this paper
• Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

  1987cited by this paper
• Activation of purified soluble guanylate cyclase by endothelium-derived relaxing factor from intrapulmonary artery and vein: stimulation by acetylcholine, bradykinin and arachidonic acid.

  1986cited by this paper
• Modulation of vascular smooth muscle contraction by the endothelium.

  1986cited by this paper
• A new generation of Ca2+ indicators with greatly improved fluorescence properties.

  1985cited by this paper
• The role of protein kinase C in cell surface signal transduction and tumour promotion

  1984cited by this paper
• Inositol 1,4,5-trisphosphate releases Ca2+ from intracellular store sites in skinned single cells of porcine coronary artery.

  1984cited by this paper
• Inositol trisphosphate, a novel second messenger in cellular signal transduction

  1984cited by this paper
• Agonist‐Induced Endothelium‐Dependent Relaxation in Rat Thoracic Aorta May Be Mediated through cGMP

  1983cited by this paper
• Increased thromboxane B2 biosynthesis in platelets

  1982cited by this paper
• Nitroglycerin stimulates synthesis of prostacyclin by cultured human endothelial cells.

  1981cited by this paper
• Bovine endothelial cells in culture produce thromboxane as well as prostacyclin.

  1981cited by this paper
• Rapid extraction of oxygenated metabolites of arachidonic acid from biological samples using octadecylsilyl silica.

  1980cited by this paper
• The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine

  1980cited by this paper
• Dansylcadaverine inhibits internalization of 125I-epidermal growth factor in BALB 3T3 cells.

  1980cited by this paper
• Nitric oxide activates guanylate cyclase and increases guanosine 3':5'-cyclic monophosphate levels in various tissue preparations.

  1977cited by this paper
• An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

  1976cited by this paper
• PINOCYTOSIS IN FIBROBLASTS

  1974cited by this paper
• Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.

  1973cited by this paper

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  2022cites this paper
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  2010cites this paper
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  2009cites this paper
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• Endothelin-1 and cerebral blood flow in a porcine model.

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• Estrogen and vascular resistance (Endocrine Hypertension)

  2006cites this paper
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• [Toxicity of cadmium and lead on vascular cells that regulate fibrinolysis].

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  1998cites this paper
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  1997cites this paper
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• [Cellular mechanisms of endothelial endothelin synthesis].

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• The pathogenesis of cardiovascular disease: role of the endothelium as a target and mediator.

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  1995cites this paper
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  1993cites this paper
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