N-cofilin is associated with neuronal migration disorders and cell cycle control in the cerebral cortex.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Genes & Development

• Publication date

  2007-09-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/GAD.434307PMID 17875668PMCID PMC1973148
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Proliferative behavior of the murine cerebral wall in tissue culture: cell cycle kinetics and checkpoints.

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  1999cited by this paper
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  1998cited by this paper
• Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes.

  1997cited by this paper
• Xenopus laevis actin-depolymerizing factor/cofilin: a phosphorylation- regulated protein essential for development

  1996cited by this paper
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  1996cited by this paper
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  1993cited by this paper
• Cell cycle dependence of laminar determination in developing neocortex.

  1992cited by this paper
• Nucleotide sequence and expression of a cDNA encoding chick brain actin depolymerizing factor.

  1990cited by this paper
• Cloning and characterization of porcine brain cofilin cDNA. Cofilin contains the nuclear transport signal sequence.

  1988cited by this paper
• Experimentally induced alteration in the polarity of developing neurons

  1987cited by this paper
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  1982cited by this paper
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  1981influential reference
• Neuronal migration and contact guidance in the primate telencephalon.

  1978cited by this paper
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  1974cited by this paper

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