Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans.

A. Thorarensen,M. Dowty,M. Banker,B. Juba,J. Jussif,Tsung H. Lin,F. Vincent,R. Czerwinski,A. Casimiro-Garcia,R. Unwalla,J. Trujillo,Sidney Liang,P. Balbo,Ye Che,A. Gilbert,Matthew F Brown,M. Hayward,J. Montgomery,Louis Leung,Xin Yang,S. Soucy,M. Hegen,J. Coe,Jonathan D. Langille,F. Vajdos,J. Chrencik,J. Telliez

Published 2017 in Journal of Medicinal Chemistry

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