Positron emission tomography studies have correlated changes in the cerebral metabolic rate of glucose utilization (CMRglu) with symptoms of depression, aggression, impulsivity, and hyperactivity. Psychiatric disorders in which these symptoms are manifested are disproportionately represented among the sexes. We evaluated gender differences in regional CMRglu in control subjects (21 men and 18 women) with particular interest in the global, orbital frontal, and left anterolateral prefrontal cortical (LAPFC) CMRglu. A trend was present for global CMRglu to be greater in women than in men. Regional CMRglu was lower in men than in women in the orbital frontal area. No differences were observed in the LAPFC region.
Gender-related differences in regional cerebral glucose metabolism in normal volunteers.
P. Andreason,A. Zametkin,A. C. Guo,Paul Baldwin,R. Cohen
Published 1994 in Psychiatry Research
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- Publication year
1994
- Venue
Psychiatry Research
- Publication date
1994-02-01
- Fields of study
Medicine, Psychology
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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