Nano-interventions for neurodegenerative disorders.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Pharmacological Research

• Publication date

  2010-08-01

• Fields of study

  Biology, Medicine, Materials Science

• Identifiers
  DOI 10.1016/j.phrs.2010.02.004PMID 20153429
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Active efflux across the blood-brain barrier: Role of the solute carrier family

  2011cited by this paper
• The role of the blood-CNS barrier in CNS disorders and their treatment.

  2010cited by this paper
• Colloidal nanocarriers: a review on formulation technology, types and applications toward targeted drug delivery.

  2010cited by this paper
• Approaches to transport therapeutic drugs across the blood-brain barrier to treat brain diseases.

  2010cited by this paper
• Dual-targeting daunorubicin liposomes improve the therapeutic efficacy of brain glioma in animals.

  2010cited by this paper
• Evaluation of cationic liposomes composed of an amino acid-based lipid for neuronal transfection.

  2010cited by this paper
• Mechanisms of endocytosis.

  2009cited by this paper
• Functional Protein Delivery into Neurons Using Polymeric Nanoparticles*

  2009cited by this paper
• The blood-brain barrier in brain homeostasis and neurological diseases.

  2009cited by this paper
• Novel formulation approaches for optimising delivery of anticancer drugs based on P-glycoprotein modulation.

  2009cited by this paper
• On the mechanism and dynamics of uptake and permeation of polyether-copolyester dendrimers across an in vitro blood-brain barrier model.

  2009cited by this paper
• Lipid nanocapsules: a new platform for nanomedicine.

  2009cited by this paper
• Brain-Targeting Mechanisms of Lactoferrin-Modified DNA-Loaded Nanoparticles

  2009cited by this paper
• Delivery of peptide and protein drugs over the blood-brain barrier.

  2009cited by this paper
• Nanocarriers’ entry into the cell: relevance to drug delivery

  2009cited by this paper
• Nanoparticles in cellular drug delivery.

  2009cited by this paper
• Indomethacin-loaded nanocapsules treatment reduces in vivo glioblastoma growth in a rat glioma model.

  2009cited by this paper
• Dendrimer nanocarriers as versatile vectors in gene delivery.

  2009cited by this paper
• Future prospects of nanoparticles on brain targeted drug delivery

  2009cited by this paper
• Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones.

  2009cited by this paper
• Nanotechnology olymer-based nanocapsules for drug delivery

  2009cited by this paper
• Challenges and opportunities in CNS delivery of therapeutics for neurodegenerative diseases

  2009cited by this paper
• Clinical toxicities of nanocarrier systems.

  2008cited by this paper
• Cytotoxicity and apoptosis enhancement in brain tumor cells upon coadministration of paclitaxel and ceramide in nanoemulsion formulations.

  2008cited by this paper
• Quantitative Investigation of the Role of Breast Cancer Resistance Protein (Bcrp/Abcg2) in Limiting Brain and Testis Penetration of Xenobiotic Compounds

  2008cited by this paper
• Methotrexate loaded polyether-copolyester dendrimers for the treatment of gliomas: enhanced efficacy and intratumoral transport capability.

  2008cited by this paper
• Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells.

  2008cited by this paper
• CNS Delivery Via Adsorptive Transcytosis

  2008cited by this paper
• Potential of solid lipid nanoparticles in brain targeting.

  2008cited by this paper
• Delivery of serotonin to the brain by monocytes following phagocytosis of liposomes.

  2008cited by this paper
• Ostwald Ripening ofβ-Carotene Nanoparticles

  2007cited by this paper
• A review of the formation and classification of amphiphilic block copolymer nanoparticulate structures: micelles, nanospheres, nanocapsules and polymersomes.

  2007cited by this paper
• Angiotensin II Controls Occludin Function and Is Required for Blood–Brain Barrier Maintenance: Relevance to Multiple Sclerosis

  2007cited by this paper
• Apolipoprotein A-I coating of protamine-oligonucleotide nanoparticles increases particle uptake and transcytosis in an in vitro model of the blood-brain barrier.

  2007cited by this paper
• Solid lipid nanoparticles for targeted brain drug delivery.

  2007cited by this paper
• Cationic liposomes, loaded with m-THPC, in photodynamic therapy for malignant glioma.

  2007cited by this paper
• What do we (need to) know about the kinetic properties of nanoparticles in the body?

  2007cited by this paper
• Expression of the ATP-binding Cassette Membrane Transporter, ABCG2, in Human and Rodent Brain Microvessel Endothelial and Glial Cell Culture Systems

  2007cited by this paper
• Nano-emulsions and nanocapsules by the PIT method: an investigation on the role of the temperature cycling on the emulsion phase inversion.

  2007cited by this paper
• Ostwald ripening of beta-carotene nanoparticles.

  2007cited by this paper
• Lack of Support for a Role for RLIP76 (RALBP1) in Response to Treatment or Predisposition to Epilepsy

  2007cited by this paper
• Endocytosis at the blood–brain barrier: From basic understanding to drug delivery strategies

  2006cited by this paper
• Toxic Potential of Materials at the Nanolevel

  2006cited by this paper
• Is nanotechnology ready for primetime?

  2006cited by this paper
• Nanotechnology and Nanotoxicology

  2006cited by this paper
• Biomedical applications and potential health risks of nanomaterials: molecular mechanisms.

  2006cited by this paper
• Oral nanoparticle-based antituberculosis drug delivery to the brain in an experimental model.

  2006cited by this paper
• Pharmacokinetics, tissue distribution and bioavailability of nitrendipine solid lipid nanoparticles after intravenous and intraduodenal administration

  2006cited by this paper
• Nanomedicines and nanotoxicology: some physiological principles.

  2006cited by this paper
• Etoposide nanocarriers suppress glioma cell growth by intracellular drug delivery and simultaneous P-glycoprotein inhibition.

  2006cited by this paper
• Polymer genomics: an insight into pharmacology and toxicology of nanomedicines.

  2006cited by this paper
• Targeted brain delivery of AZT via transferrin anchored pegylated albumin nanoparticles

  2006cited by this paper
• In Situ Localization of P-glycoprotein (ABCB1) in Human and Rat Brain

  2006cited by this paper
• Nanomedicine: An unresolved regulatory issue.

  2006cited by this paper
• RLIP76, a non-ABC transporter, and drug resistance in epilepsy

  2005cited by this paper
• Nanomedicine and nanotoxicology: two sides of the same coin.

  2005cited by this paper
• Nanomedicine: current status and future prospects

  2005cited by this paper
• Colloidal carriers and blood-brain barrier (BBB) translocation: a way to deliver drugs to the brain?

  2005cited by this paper
• Clathrin- and non-clathrin-mediated endocytic regulation of cell signalling

  2005cited by this paper
• Evolution of the ATP-binding cassette (ABC) transporter superfamily in vertebrates.

  2005cited by this paper
• Blood-brain barrier active efflux transporters: ATP-binding cassette gene family

  2005cited by this paper
• Nanotoxicology: An Emerging Discipline Evolving from Studies of Ultrafine Particles

  2005cited by this paper
• Role of drug efflux transporters in the brain for drug disposition and treatment of brain diseases.

  2005cited by this paper
• Metalloproteinases: Mediators of Pathology and Regeneration in the CNS

  2005cited by this paper
• Nano-emulsion formulation using spontaneous emulsification: solvent, oil and surfactant optimisation.

  2004cited by this paper
• The ABC Transporters MDR1 and MRP2: Multiple Functions in Disposition of Xenobiotics and Drug Resistance

  2004cited by this paper
• A pericyte‐derived angiopoietin‐1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie‐2 activation in vitro

  2004cited by this paper
• Long-term shelf stability of amphiphilic β-cyclodextrin nanosphere suspensions monitored by dynamic light scattering and cryo-transmission electron microscopy

  2004cited by this paper
• Targeting intracellular targets.

  2004cited by this paper
• Improving lipoplex-mediated gene transfer into C6 glioma cells and primary neurons.

  2004cited by this paper
• Blood-brain barrier drug targeting: the future of brain drug development.

  2003cited by this paper
• SSeCKS regulates angiogenesis and tight junction formation in blood-brain barrier

  2003cited by this paper
• Effect of high pressure homogenisation on methylcellulose as food emulsifier

  2003cited by this paper
• Drug efflux transporters in the CNS.

  2003cited by this paper
• Beyond biotechnology: FDA regulation of nanomedicine.

  2003cited by this paper
• Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems.

  2003cited by this paper
• Polyester-Poly(Ethylene Glycol) Nanoparticles Loaded with the Pure Antiestrogen RU 58668: Physicochemical and Opsonization Properties

  2003cited by this paper
• Enhanced brain targeting by synthesis of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine and incorporation into solid lipid nanoparticles.

  2002cited by this paper
• Tight junctions of the blood-brain barrier: development, composition and regulation.

  2002cited by this paper
• The Impact of Efflux Transporters in the Brain on the Development of Drugs for CNS Disorders

  2002cited by this paper
• Junctional complexes of the blood-brain barrier: permeability changes in neuroinflammation.

  2002cited by this paper
• Nanoparticle Technology for Drug Delivery Across the Blood-Brain Barrier

  2002cited by this paper
• Biodegradable polymeric nanoparticles as drug delivery devices.

  2001cited by this paper
• Mechanism of sensitization of MDR cancer cells by Pluronic block copolymers: Selective energy depletion

  2001cited by this paper
• Peptide drug modifications to enhance bioavailability and blood-brain barrier permeability.

  2001cited by this paper
• Essential polyunsaturated fatty acids and the barrier to the brain

  2001cited by this paper
• Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization.

  2001cited by this paper
• Lipid-DNA and lipid-polyelectrolyte mesophases: structure and exchange kinetics.

  2000cited by this paper
• Emulsification by ultrasound: drop size distribution and stability.

  1999cited by this paper
• Diblock copolymer nanoparticles for drug delivery.

  1998cited by this paper
• Advances in neurology.

  1996cited by this paper
• Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer.

  1996cited by this paper
• Pathway across blood-brain barrier opened by the bradykinin agonist, RMP-7.

  1995cited by this paper
• The controlled intravenous delivery of drugs using PEG-coated sterically stabilized nanospheres.

  1995cited by this paper
• Nonpermeable and permeable vessels of the brain.

  1992cited by this paper
• A new class of drug carriers: micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain☆

  1992cited by this paper
• Microangiopathy, the vascular basement membrane and Alzheimer's disease: a review.

  1990cited by this paper
• Transport of calcium and other metals across the blood-brain barrier: mechanisms and implications for neurodegenerative disorders.

  1990cited by this paper
• Electrical resistance across the blood‐brain barrier in anaesthetized rats: a developmental study.

  1990cited by this paper
• Drug Delivery to the Brain by Blood-Brain Barrier Circumvention and Drug Modification

  1989cited by this paper

• RLIP76: a versatile ATP-dependent transporter as a pharmacotherapeutic target for epilepsy management.

  2026cites this paper
• Precision targeting of the CNS: recent progress in brain-directed nanodrug delivery

  2025cites this paper
• Intranasal delivery of Chitosan-based nanoparticles as an innovative way for management of neurodegenerative disorders: a comprehensive review of advanced strategies for CNS targeting

  2024cites this paper
• Nanotechnology-empowered therapeutics targeting neurodegenerative diseases.

  2023cites this paper
• Potential Neuroprotective Strategies using Smart Drug Delivery Systems for Alzheimer's Disease.

  2023cites this paper
• Correlating the Structure and Gene Silencing Activity of Oligonucleotide-Loaded Lipid Nanoparticles Using Small-Angle X-ray Scattering

  2023cites this paper
• Research Progress of Nanocarriers for the Treatment of Alzheimer's Disease.

  2022cites this paper
• Protein and Gene Delivery Systems for Neurodegenerative Disorders: Where Do We Stand Today?

  2022cites this paper
• From the nose to the brain, nanomedicine drug delivery

  2021cites this paper
• A comprehensive review of nano drug delivery system in the treatment of CNS disorders

  2020cites this paper
• Applications of Nanomaterials in Human Health

  2020cites this paper
• Chitosan coated synergistically engineered nanoemulsion of Ropinirole and nigella oil in the management of Parkinson's disease: Formulation perspective and In vitro and In vivo assessment.

  2020cites this paper
• Applications of Nanomaterials in Neurological Diseases, Neuronal Differentiation, Neuronal Protection, and Neurotoxicity

  2020cites this paper
• Recent Advances in Nanocarrier-Based Brain-Targeted Drug Delivery for Effective Treatment of Central Nervous System Disorders

  2020cites this paper
• Techniques to Produce Liposomes for the Emerging Market of Nano-Based Formulations

  2020cites this paper
• Magnetic hybrid materials interact with biological matrices

  2020influential citation
• Recent strategies and advances in the fabrication of nano lipid carriers and their application towards brain targeting.

  2020cites this paper
• Intranasal Nanoemulsions for Direct Nose-to-Brain Delivery of Actives for CNS Disorders

  2020cites this paper
• Intranasal drug delivery: Novel delivery route for effective management of neurological disorders

  2019cites this paper
• Alzheimer's Disease Targeted Nano-Based Drug Delivery Systems.

  2019cites this paper
• Emerging vistas in theranostic medicine

  2019cites this paper
• Impact of molecular rearrangement of amphiphilic stabilizers on physical stability of itraconazole nanoparticles prepared by flash nanoprecipitation

  2018cites this paper
• Nano-carrier enabled drug delivery systems for nose to brain targeting for the treatment of neurodegenerative disorders

  2018cites this paper
• Lipid Nanocarriers for Intracellular Delivery

  2018cites this paper
• Investigating the Effect of Intraperitoneal Administration of Zinc Oxide Nanoparticles on the Model of Postpartum Depression in Adult Female Mice

  2018cites this paper
• Treatment of neurodegenerative disorders through the blood-brain barrier using nanocarriers.

  2018cites this paper
• Interplay between Amphiphilic Stabilizers and Cholesterol in the Stabilization of Itraconazole Nanoparticles Prepared by Flash Nanoprecipitation.

  2018cites this paper
• Non-invasive approaches for drug delivery to the brain based on the receptor mediated transport.

  2017cites this paper
• Development of Nasal Lipid Nanocarriers Containing Curcumin for Brain Targeting

  2017cites this paper
• Nanomaterial applications for neurological diseases and central nervous system injury

  2017cites this paper
• Therapeutic nanomedicine surmounts the limitations of pharmacotherapy

  2017cites this paper
• Strategies of Engineering Nanoparticles for Treating Neurodegenerative Disorders.

  2017cites this paper
• Glutathione-decorated dendrons as potential drug carrier systems in Multiple Sclerosis

  2017cites this paper
• Nanomedicine in Central Nervous System (CNS) Disorders: A Present and Future Prospective.

  2016cites this paper
• Cytotoxicity and apoptotic gene expression in an in vitro model of the blood–brain barrier following exposure to poly(butylcyanoacrylate) nanoparticles

  2016cites this paper
• Evaluation of various block copolymers for micelle formation and brain drug delivery: In vitro characterization and cellular uptake studies

  2016cites this paper
• THE‘MAGIC BULLET’ NANOMEDICINE –AS A MOLECULAR DRUG CARRIER FOR TARGETING INFLAMMATION IN RHEUMATOID ARTHRITIS

  2016cites this paper
• Targeted Drug Delivery : Concepts and Design

  2015cites this paper
• RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies.

  2015cites this paper
• Farmacotoxicidad en la vehiculización de principios activos en la enfermedad de Parkinson

  2015cites this paper
• Novel Approaches for the Delivery of Biologics to the Central Nervous System

  2015cites this paper
• Traumatic Brain Injury and Neurodegenerative Disease: A Literature Review

  2015cites this paper
• Nanotoxicology: Contemporary Issues and Future Directions

  2015cites this paper
• Stimuli-Responsive Nanocarriers for Drug Delivery to the Central Nervous System

  2015cites this paper
• Advances in Neurotherapeutic Delivery Technologies

  2015cites this paper
• Blood-to-Brain Drug Delivery Using Nanocarriers

  2014cites this paper
• Nanoparticulate systems as drug carriers: the need

  2014cites this paper
• Engineered nanoparticles. How brain friendly is this new guest?

  2014cites this paper
• Nanomedicine and its application in treatment of microglia-mediated neuroinflammation.

  2014cites this paper
• Colloidal soft nanocarrier for transdermal delivery of dopamine agonist: ex vivo and in vivo evaluation.

  2014cites this paper
• Preparation, characterization and in vivo evaluation of nanoemulsions for the controlled delivery of the antiobesity agent N-oleoylethanolamine.

  2014cites this paper
• Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

  2014cites this paper
• Nanomedicines for nervous system diseases

  2014cites this paper
• Nanotechnology-Based Drug Delivery Systems for Targeting, Imaging and Diagnosis of Neurodegenerative Diseases

  2013cites this paper
• Advances in brain drug targeting and delivery: limitations and challenges of solid lipid nanoparticles

  2013cites this paper
• Lipid nanocarriers containing ester prodrugs of flurbiprofen preparation, physical-chemical characterization and biological studies.

  2013cites this paper
• Nanotechnology for neurodegenerative disorders.

  2012cites this paper
• Complement system and the brain: selected pathologies and avenues toward engineering of neurological nanomedicines.

  2012cites this paper
• Nanowired drug delivery for neuroprotection in central nervous system injuries: modulation by environmental temperature, intoxication of nanoparticles, and comorbidity factors.

  2012cites this paper
• Nanoparticles and spermatogenesis: how do nanoparticles affect spermatogenesis and penetrate the blood-testis barrier.

  2012cites this paper
• Nanowired drug delivery to enhance neuroprotection in spinal cord injury.

  2012cites this paper
• Effects of nanoparticle zinc oxide on spatial cognition and synaptic plasticity in mice with depressive-like behaviors

  2012cites this paper
• Antiglioma activity of curcumin-loaded lipid nanoparticles and its enhanced bioavailability in brain tissue for effective glioblastoma therapy.

  2012cites this paper
• THERAPEUTIC-LOADED LIPID NANOSTRUCTURES AND BRAIN DISEASES.

  2012cites this paper
• BLOOD BRAIN BARRIER: SURFACE MODIFIED NANOCARRIERS AND IN VITRO MODELS TO TREAT ALZHEIMER'S DISEASE - A REVIEW

  2012cites this paper
• Ligand-mediated transport of drug delivery devices across the blood-brain barrier

  2012cites this paper
• The Role of Nanomedicine in Cell Based Therapeutics in Cancer and Inflammation

  2012cites this paper
• Nanowired drug delivery of antioxidant compound H-290/51 enhances neuroprotection in hyperthermia-induced neurotoxicity.

  2012cites this paper
• Nanotechnology for neurodegenerative disorders.

  2012cites this paper
• Effects of PEG-interferon alpha plus ribavirin on tryptophan metabolism in patients with chronic hepatitis C.

  2011cites this paper
• The current state of engineered nanomaterials in consumer goods and waste streams: the need to develop nanoproperty-quantifiable sensors for monitoring engineered nanomaterials.

  2011cites this paper
• Polymeric nanoparticles - targeted drug delivery systems for treatment of CNS disorders and their possible endocrine disrupting activities.

  2011cites this paper
• Nanoemulsions for drug delivery through different routes

  2011cites this paper
• Molecular nanoclinics: Dream or reality?

  2010cites this paper