Human pigmentation genetics: the difference is only skin deep

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Bioessays

• Publication date

  1998-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/(SICI)1521-1878(199809)20:9<712::AID-BIES4>3.0.CO;2-IPMID 9819560
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Human Evolution

  2019cited by this paper
• Complete sequence and polymorphism study of the human TYRP1 gene encoding tyrosinase-related protein 1

  2009cited by this paper
• Complementation of hypopigmentation in p-mutant (pink-eyed dilution) mouse melanocytes by normal human P cDNA, and defective complementation by OCA2 mutant sequences.

  1997cited by this paper
• Hypopigmentation in the Prader-Willi syndrome correlates with P gene deletion but not with haplotype of the hemizygous P allele.

  1997cited by this paper
• Oculocutaneous albinism (OCA2) in sub-Saharan Africa: distribution of the common 2.7-kb P gene deletion mutation

  1997influential reference
• Characterization of melanocyte stimulating hormone receptor variant alleles in twins with red hair.

  1997cited by this paper
• Rufous oculocutaneous albinism in southern African Blacks is caused by mutations in the TYRP1 gene.

  1997cited by this paper
• Human evolution

  1996cited by this paper
• The genetics of pigmentation: from fancy genes to complex traits.

  1996cited by this paper
• Mutation in and lack of expression of tyrosinase-related protein-1 (TRP-1) in melanocytes from an individual with brown oculocutaneous albinism: a new subtype of albinism classified as "OCA3".

  1996cited by this paper
• What is a caucasian?

  1996cited by this paper
• Comparison of phenotype in uniparental disomy and deletion Prader-Willi syndrome: sex specific differences.

  1996cited by this paper
• Phenotypic differences in Angelman syndrome patients: imprinting mutations show less frequently microcephaly and hypopigmentation than deletions.

  1996cited by this paper
• Cysteine deprivation promotes eumelanogenesis in human melanoma cells.

  1996cited by this paper
• Assignment of Genes Coding for Brown Eye Colour (BEY2) and Brown Hair Colour (HCL3) on Chromosome 15q

  1996cited by this paper
• The pinkeyed-dilution protein and the eumelanin/pheomelanin switch: in support of a unifying hypothesis.

  1995cited by this paper
• Chromosomal structure of the human TYRP1 and TYRP2 loci and comparison of the tyrosinase-related protein gene family.

  1995influential reference
• Organization and sequence of the human P gene and identification of a new family of transport proteins.

  1995influential reference
• Variants of the melanocyte–stimulating hormone receptor gene are associated with red hair and fair skin in humans

  1995cited by this paper
• Melanosomal tyrosine transport in normal and pink-eyed dilution murine melanocytes.

  1995cited by this paper
• Structural organization of the human tyrosinase gene and sequence analysis and characterization of its promoter region.

  1994cited by this paper
• Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis.

  1994cited by this paper
• Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA.

  1994cited by this paper
• The tyrosinase gene family--interactions of melanogenic proteins to regulate melanogenesis.

  1994cited by this paper
• Identification of a melanosomal membrane protein encoded by the pink-eyed dilution (type II oculocutaneous albinism) gene.

  1994cited by this paper
• High-molecular-weight forms of tyrosinase and the tyrosinase-related proteins: evidence for a melanogenic complex.

  1994cited by this paper
• African origin of an intragenic deletion of the human P gene in tyrosinase positive oculocutaneous albinism

  1994influential reference
• Mapping of the gene encoding the melanocortin-1 (alpha-melanocyte stimulating hormone) receptor (MC1R) to human chromosome 16q24.3 by Fluorescence in situ hybridization.

  1994cited by this paper
• A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1).

  1994cited by this paper
• Analysis of tyrosinase mutations associated with tyrosinase-related oculocutaneous albinism (OCA1).

  1994cited by this paper
• Mutations of the P gene in oculocutaneous albinism, ocular albinism, and Prader-Willi syndrome plus albinism.

  1994cited by this paper
• Molecular and developmental genetics of mouse coat color.

  1994influential reference
• Brown oculocutaneous albinism is allelic to tyrosinase-positive oculocutaneous albinism in southern African Negroids

  1994cited by this paper
• Dinucleotide repeat polymorphism at the human TYRP1 locus.

  1994cited by this paper
• Assignment of the tyrosinase-related protein-2 gene (TYRP2) to human chromosome 13q31-q32 by fluorescence in situ hybridization: extended synteny with mouse chromosome 14.

  1994cited by this paper
• Diverse mutations of the P gene among African-Americans with type II (tyrosinase-positive) oculocutaneous albinism (OCA2).

  1994cited by this paper
• A gene for the mouse pink-eyed dilution locus and for human type II oculocutaneous albinism

  1993cited by this paper
• Unraveling the melanocyte.

  1993cited by this paper
• Hair melanins and hair color: ultrastructural and biochemical aspects.

  1993cited by this paper
• Pigmentation phenotypes of variant extension locus alleles result from point mutations that alter MSH receptor function.

  1993cited by this paper
• Role of tyrosinase as the determinant of pigmentation in cultured human melanocytes.

  1993cited by this paper
• Contribution of melanogenic proteins to the heterogeneous pigmentation of human melanocytes.

  1993cited by this paper
• Postnatal ocular expression of tyrosinase and related proteins: disruption by the pink-eyed unstable (p(un)) mutation.

  1993cited by this paper
• Unraveling the melanocyte.

  1993cited by this paper
• Molecular cloning and expression of the human melanocyte stimulating hormone receptor cDNA

  1992cited by this paper
• The function of melanin or six blind people examine an elephant.

  1992cited by this paper
• Melanins and melanogenesis

  1992influential reference
• The cloning of a family of genes that encode the melanocortin receptors.

  1992cited by this paper
• The tyrosinase-positive oculocutaneous albinism locus maps to chromosome 15q11.2-q12.

  1992cited by this paper
• An MboI polymorphism at codon 192 of the human tyrosinase gene is present in Asians and Afrocaribbeans.

  1992cited by this paper
• The Mouse Pink-Eyed Dilution Gene: Association with Human Prader-Willi and Angelman Syndromes

  1992cited by this paper
• A second tyrosinase‐related protein, TRP‐2, maps to and is mutated at the mouse slaty locus.

  1992cited by this paper
• After dopachrome?

  1991cited by this paper
• A polymorphism of the human tyrosinase gene is associated with temperature-sensitive enzymatic activity.

  1991cited by this paper
• Enzymatic control of pigmentation in mammals

  1991cited by this paper
• Organization and nucleotide sequences of the human tyrosinase gene and a truncated tyrosinase-related segment.

  1991cited by this paper
• Nucleotide sequence of the cDNA encoding human tyrosinase-related protein.

  1990cited by this paper
• RFLP for MboI in the human tyrosinase (TYR) gene detected by PCR.

  1990cited by this paper
• Melanization in albino mice transformed by introducing cloned mouse tyrosinase gene.

  1990cited by this paper
• Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.

  1990cited by this paper
• The melanocyte. Its structure, function, and subpopulations in skin, eyes, and hair.

  1988cited by this paper
• Isolation and sequence of a cDNA clone for human tyrosinase that maps at the mouse c-albino locus.

  1987cited by this paper
• Differentiation of heterozygotes in recessive albinism.

  1986cited by this paper
• Cloning and expression of cDNA encoding mouse tyrosinase.

  1986cited by this paper
• Estimating the number of loci determining skin colour in a hybrid population.

  1981cited by this paper
• Alteration of racial differences in melanosome distribution in human epidermis after exposure to ultraviolet light.

  1972cited by this paper
• The Genetics of Red Hair

  1969cited by this paper
• The genetics of red hair.

  1969cited by this paper
• Racial Differences in the Fate of Melanosomes in Human Epidermis

  1969cited by this paper
• The inheritance of red hair.

  1967cited by this paper
• INHERITANCE OF RED HAIR FOR SIX GENERATIONS

  1964cited by this paper
• Studies on the inheritance of human skin colour

  1964cited by this paper
• The measurement and inheritance of skin colour in man.

  1957cited by this paper
• HAIR‐COLOUR VARIATION IN THE UNITED KINGDOM *

  1956cited by this paper
• Model estimates of the frequency of white and near-white segregants in the American Negro.

  1953cited by this paper
• Red hair colour as a genetical character.

  1952cited by this paper
• Marriage of Two Complete Albinos with Normally Pigmented Offspring *

  1952cited by this paper
• CONCERNING THE INHERITANCE OF RED HAIR

  1943cited by this paper
• Distribution of red hair according to age

  1934cited by this paper
• COLOR INHERITANCE IN MAMMALS IX, The Dog—Many Kinds of White Patterns Found—Albinism Resembles That of Other Mammals in Reducing Red More Than Black—Inheritance of Black-and-Tan Requires Further Data—Red and Liver Simple Recessives

  1918cited by this paper
• COLOR INHERITANCE IN MAMMALS II. The Mouse—Better Adapted to Experimental Work than Any Other Mammal—Seven Sets of Mendelian Allelomorphs Identified—Factorial Hypothesis Framed by Cuenot on Basis of His Work with Mice

  1917cited by this paper
• Heredity of Skin Pigmentation in Man

  1910cited by this paper
• Heredity of Hair Color in Man

  1909cited by this paper
• Heredity of eye-color in man

  1907cited by this paper
• COLOR INHERITANCE IN MAMMALS.

  1907cited by this paper

• DOPA Decarboxylase (DDC) in Pacific Oysters: Characterization and Role in Tyrosine Metabolism and Melanogenesis

  2025cites this paper
• Exploring physiological differences in injury response by skin tone: A scoping review.

  2025cites this paper
• Zinc in eye health, retinal biology and disease.

  2025cites this paper
• Catechin-7-O-α-L-rhamnopyranoside can reduce α-MSH-induced melanogenesis in B16F10 melanoma cells through competitive inhibition of tyrosinase

  2022cites this paper
• Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis

  2021cites this paper
• Active Compound and Heavy Metals in Bleaching Creams and Their Health Effects: A Review

  2021influential citation
• A Comprehensive Review on Basal Cell Carcinoma of the Head-And-Neck Region

  2021cites this paper
• Influence of Ethnicities and Skin Color Variations in Different Populations: A Review

  2021cites this paper
• Forensic DNA Phenotyping

  2020cites this paper
• Factors affecting superficial vein visibility at the upper limb in healthy young adults: A cross-sectional observational study

  2020cites this paper
• Pigmentation and vision: Is GPR143 in control?

  2019cites this paper
• CELLULAR BIOLOGICAL AND EUMELANIN-RELATED GENE EXPRESSIONAL BASES OF PIGMENT DEVIATION OF LEPTOBOTIA TAENIOPS

  2019cites this paper
• Simulation of temperature distribution in different human skin types exposed to laser irradiation with different wavelengths and laser irradiation intensities

  2019cites this paper
• Effect of microsolvation on the non-radiative decay of the eumelanin monomer.

  2019cites this paper
• CRISPR/Cas9‐mediated ebony knockout results in puparium melanism in Spodoptera litura

  2019cites this paper
• Kinship verification from face images in discriminative subspaces of color components

  2018cites this paper
• Quantifying Forearm Soft Tissue Motion and Shock Attenuation following Hand Impacts Consistent with Forward Falls using Massless Skin Surface Markers

  2017cites this paper
• Isolation and Characterization of Isofraxidin 7-O-(6′-O-p-Coumaroyl)-β-glucopyranoside from Artemisia capillaris Thunberg: A Novel, Nontoxic Hyperpigmentation Agent That Is Effective In Vivo

  2017cites this paper
• Cutaneous pigmentation modulates skin sensitivity via tyrosinase-dependent dopaminergic signalling

  2017cites this paper
• Advancements in forensic DNA-based identification

  2017cites this paper
• Tyrosinase Inhibitory Effect of (E)-2-(substituted benzylidene)-2,3-dihydro-1H-cyclopenta[a]naphthalen-1-one Derivatives

  2017cites this paper
• African ancestry is associated with facial melasma in women: a cross-sectional study

  2017cites this paper
• TERT promoter mutations associate with MC1R variants in melanoma patients

  2017cites this paper
• The Contribution of Neanderthals to Phenotypic Variation in Modern Humans

  2017cites this paper
• Photodermatoses in the Pigmented Skin.

  2017cites this paper
• Evolution of skin and hair in African Americans.

  2016cites this paper
• Human Phenotypic Diversity: An Evolutionary Perspective.

  2016cites this paper
• Elucidating the mechanisms or interactions involved in differing hair color follicles

  2016cites this paper
• TPC2 controls pigmentation by regulating melanosome pH and size

  2016cites this paper
• Mystique: The Ultimate Mutant

  2016cites this paper
• Current Challenges in Understanding the Story of Skin Pigmentation — Bridging the Morpho-Anatomical and Functional Aspects of Mammalian Melanocytes

  2015cites this paper
• Is Parental Love Colorblind? Human Capital Accumulation within Mixed Families

  2015cites this paper
• On the Blurring of the Color Line: Wages and Employment for Black Males of Different Skin Tones

  2015cites this paper
• AVALIAÇÃO COMPARATIVA DA ANCESTRALIDADE EM MULHERES COM MELASMA FACIAL: UM ESTUDO TRANSVERSAL

  2015cites this paper
• Paternal/Maternal and Dominance/Recessiveness Modes of Inheritance with Medically-Important Genetics Aspects in Islamic-Arabic Civilization

  2015cites this paper
• Amyloids, melanins and oxidative stress in melanomagenesis

  2015cites this paper
• Keratinocyte Differentiation and Epigenetics

  2015cites this paper
• Mosaic Tetrasomy 13q and Phylloid Hypomelanosis: A Case Report and Review of the Literature

  2015cites this paper
• An Updated Organic Classification of Tyrosinase Inhibitors on Melanin Biosynthesis

  2015cites this paper
• Ultraviolet Radiation-Induced Cytogenetic Damage in White, Hispanic and Black Skin Melanocytes: A Risk for Cutaneous Melanoma

  2015cites this paper
• Marine Streptomyces cyaneus Strain Alex-SK121 Mediated Eco-friendly Synthesis of Silver Nanoparticles Using Gamma Radiation

  2014cites this paper
• Fisiología del sistema pigmentario. Melanogénesis

  2014cites this paper
• On the blurring of the color line : Wages and employment for Black males of di erent skin tones ∗

  2014cites this paper
• Molecular and Genetic Insights on Oculocutaneous Albinism

  2014cites this paper
• Progressive Genetic Architecture of Human Skin Pigmentation

  2014cites this paper
• Analysis of Skin Inheritance Using FOS

  2014cites this paper
• The evolution of skin pigmentation and hair texture in people of African ancestry.

  2014cites this paper
• Multifaceted pathways protect human skin from UV radiation.

  2014cites this paper
• Inhibition of melanogenic activity by chalcone derivatives in alpha-melanocyte stimulating hormone cell line (B16-F10)

  2014cites this paper
• Genetics of adaptive traits and gender-specific demographic processes in South Asian populations

  2014cites this paper
• The Evolution of Human Skin Pigmentation

  2013cites this paper
• Adrenal function and MC1R gene analysis in a prepubertal girl with generalized hyperpigmentation: case report

  2013cites this paper
• Depigmentation Effect of Kadsuralignan F on Melan-A Murine Melanocytes and Human Skin Equivalents

  2013cites this paper
• Analysis of Genetic Dominance through Skin Biometrics Using Image Processing

  2013cites this paper
• DNA polymorphisms in humans

  2013cites this paper
• Low-Penetrance Variants and Susceptibility to Sporadic Malignant Melanoma

  2013cites this paper
• Physiologie du système pigmentaire. Mélanogenèse

  2013cites this paper
• DNA polymorphisms in humans an Liua ,

  2013cites this paper
• Comparative genomics analysis of the metallomes.

  2013cites this paper
• Comparison of Gene Expression Profiles between Keratinocytes, Melanocytes and Fibroblasts

  2013cites this paper
• FcγRIIB roll melanoomi inhibeerimisel

  2013cites this paper
• Octaphlorethol A isolated from Ishige foliacea inhibits α-MSH-stimulated induced melanogenesis via ERK pathway in B16F10 melanoma cells.

  2013cites this paper
• Colorful DNA polymorphisms in humans.

  2013cites this paper
• Inhibitory Effect of Sargassum patens on Inflammation and Melanogenesis

  2013cites this paper
• Human genetic variation: New challenges and opportunities for doping control

  2012cites this paper
• Basal Cell Carcinoma in Asians: A Retrospective Analysis of Ten Patients

  2012cites this paper
• Shining Light on Skin Pigmentation: The Darker and the Brighter Side of Effects of UV Radiation †

  2012cites this paper
• Ethnicity and Cutaneous Melanoma in the City of Sao Paulo, Brazil: A Case-Control Study

  2012cites this paper
• Phylloid Pattern of Hypomelanosis Closely Related to Chromosomal Abnormalities in the 13q Detected by SNP Array Analysis

  2012cites this paper
• Natural ambiguities: Racial categorization of multiracial individuals

  2012cites this paper
• Disorders of Pigmentation

  2011cites this paper
• The Biological Nonexistence versus the Social Existence of Human Races: Can Science Instruct the Social Ethos?

  2011cites this paper
• Unpacking human evolution to find the genetic determinants of human skin pigmentation.

  2011cites this paper
• Comparative Genomics of Trace Element Dependence in Biology*

  2011cites this paper
• Melanin and Its Role in Hyper-Pigmentation – Current Knowledge and Future Trends in Research

  2011cites this paper
• Bioconstituents from stems of Synsepalum dulcificum Daniell (Sapotaceae) inhibit human melanoma proliferation, reduce mushroom tyrosinase activity and have antioxidant properties

  2011cites this paper
• Melanocortin 1 Receptor Variants: Functional Role and Pigmentary Associations

  2011cites this paper
• Identifying melanogenesis inhibitors from Cinnamomum subavenium with in vitro and in vivo screening systems by targeting the human tyrosinase

  2011cites this paper
• The Genomic Ancestry of Individuals from Different Geographical Regions of Brazil Is More Uniform Than Expected

  2011cites this paper
• Validation of the hemoglobin (Hb) hypsochromic shift assay for determination of the time since deposition (TSD) of dried bloodstains

  2011cites this paper
• Basic Aspects of Vitamin D Nutrition

  2010cites this paper
• Récepteurs cutanés à la mélanocortine de type 1 (MC1R) et réponses oxydatives aux UVA dans des kératinocytes humains HaCaT

  2010cites this paper
• Inhibitory effects of Hoelen extract on melanogenesis in B16/F1 melanoma cells

  2010cites this paper
• Tyrosinase inhibition, free radical scavenging, antimicroorganism and anticancer proliferation activities of Sapindus mukorossi extracts

  2010cites this paper
• Inhibitory effects of 5‐chloroacetyl‐2‐piperidino‐1,3‐selenazole, a novel selenium‐containing compound, on skin melanin biosynthesis

  2010cites this paper
• USING IMAGE PROCESSING

  2010cites this paper
• Curso de Pós-graduação em Biotecnologia e Medicina Investigativa - CPqGM/Fiocruz-BA

  2010cites this paper
• GENETIC AND PHENOTYPIC DIFFERENTIATION OF QUALITATIVE TRAITS IN NIGERIAN INDIGENOUS GOAT AND SHEEP POPULATIONS

  2010cites this paper
• Genetics of pigmentation in skin cancer--a review.

  2010cites this paper
• In Vivo Virtual Biopsy of Human Skin by Using Noninvasive Higher Harmonic Generation Microscopy

  2010cites this paper
• GENETICS OF HAIR AND SKIN COLOR

  2010cites this paper
• Tetrasomy 13q mosaicism associated with phylloid hypomelanosis and precocious puberty

  2009cites this paper
• Pigmentierung und Hautkrebsrisiko

  2009cites this paper
• Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients

  2009cites this paper
• Dermoscopic features of melanomas associated with MC1R variants in Spanish CDKN2A mutation carriers

  2009cites this paper
• Inhibitory effects of arbutin on melanin biosynthesis of α-melanocyte stimulating hormone-induced hyperpigmentation in cultured brownish guinea pig skin tissues

  2009cites this paper
• The melanocortin-1 receptor gene polymorphism and association with human skin cancer.

  2009cites this paper
• Photoaging in Skin of Color

  2009cites this paper
• Pheomelanin markers in melanoma with reference to their excretion into urine

  2009cites this paper
• Global vitamin D levels in relation to age, gender, skin pigmentation and latitude: an ecologic meta-regression analysis

  2008cites this paper