Macrophage Polarization by Angiotensin II-Type 1 Receptor Aggravates Renal Injury-Acceleration of Atherosclerosis

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Arteriosclerosis, Thrombosis and Vascular Biology

• Publication date

  2011-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1161/ATVBAHA.111.237198PMID 21979434PMCID PMC3227118
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Oral activated charcoal adsorbent (AST-120) ameliorates extent and instability of atherosclerosis accelerated by kidney disease in apolipoprotein E-deficient mice.

  2011cited by this paper
• HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells

  2011cited by this paper
• Angiotensin type 1 receptor modulates macrophage polarization and renal injury in obesity.

  2011cited by this paper
• Phenotypic and functional switch of macrophages induced by regulatory CD4+CD25+ T cells in mice

  2011cited by this paper
• Monocyte angiotensin converting enzyme expression may be associated with atherosclerosis rather than arteriosclerosis in hemodialysis patients.

  2011cited by this paper
• Circulating monocyte subpopulations with high expression of angiotensin-converting enzyme predict mortality in patients with end-stage renal disease.

  2010cited by this paper
• ANG II receptor blockade enhances anti-inflammatory macrophages in anti-glomerular basement membrane glomerulonephritis.

  2010cited by this paper
• Macrophage Plasticity in Experimental Atherosclerosis

  2010cited by this paper
• Angiotensin Receptor Blocker Protection Against Podocyte-Induced Sclerosis Is Podocyte Angiotensin II Type 1 Receptor-Independent

  2010cited by this paper
• Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats.

  2010cited by this paper
• ABCA1 and ABCG1 Protect Against Oxidative Stress–Induced Macrophage Apoptosis During Efferocytosis

  2010cited by this paper
• Macrophage death and defective inflammation resolution in atherosclerosis

  2010cited by this paper
• Macrophage LRP-1 Controls Plaque Cellularity by Regulating Efferocytosis and Akt Activation

  2010cited by this paper
• Bone Marrow Angiotensin AT1 Receptor Regulates Differentiation of Monocyte Lineage Progenitors From Hematopoietic Stem Cells

  2009cited by this paper
• Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in mice.

  2009cited by this paper
• Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

  2009cited by this paper
• G2A Deficiency in Mice Promotes Macrophage Activation and Atherosclerosis

  2009cited by this paper
• Renal Dysfunction Potentiates Foam Cell Formation by Repressing ABCA1

  2009cited by this paper
• Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.

  2009cited by this paper
• M2 Macrophages Phagocytose Rituximab-Opsonized Leukemic Targets More Efficiently than M1 Cells In Vitro1

  2009cited by this paper
• PPARδ-mediated antiinflammatory mechanisms inhibit angiotensin II-accelerated atherosclerosis

  2008cited by this paper
• Liver X Receptor Activator Downregulates Angiotensin II Type 1 Receptor Expression Through Dephosphorylation of Sp1

  2008cited by this paper
• Deterioration of atherosclerosis in mice lacking angiotensin II type 1A receptor in bone marrow-derived cells

  2008cited by this paper
• Mertk Receptor Mutation Reduces Efferocytosis Efficiency and Promotes Apoptotic Cell Accumulation and Plaque Necrosis in Atherosclerotic Lesions of Apoe−/− Mice

  2008cited by this paper
• Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice.

  2008cited by this paper
• Effect of angiotensin receptor blockers on cardiovascular events in patients undergoing hemodialysis: an open-label randomized controlled trial.

  2008cited by this paper
• Critical Role of Bone Marrow Angiotensin II Type 1 Receptor in the Pathogenesis of Atherosclerosis in Apolipoprotein E–Deficient Mice

  2007cited by this paper
• Angiotensin inhibition decreases progression of advanced atherosclerosis and stabilizes established atherosclerotic plaques.

  2007cited by this paper
• Increased expression of monocytic angiotensin-converting enzyme in dialysis patients with cardiovascular disease.

  2006cited by this paper
• Transiently heightened angiotensin II has distinct effects on atherosclerosis and aneurysm formation in hyperlipidemic mice.

  2006cited by this paper
• Antiatherogenic effects of angiotensin receptor antagonism in mild renal dysfunction.

  2006cited by this paper
• Plasminogen activator inhibitor-1 deficiency protects against aldosterone-induced glomerular injury.

  2006cited by this paper
• Identification of macrophage arginase I as a new candidate gene of atherosclerosis resistance.

  2006cited by this paper
• Candesartan, an angiotensin II type-1 receptor blocker, reduces cardiovascular events in patients on chronic haemodialysis--a randomized study.

  2006cited by this paper
• Bone Marrow Transplantation Reveals That Recipient AT1a Receptors Are Required to Initiate Angiotensin II–Induced Atherosclerosis and Aneurysms

  2006cited by this paper
• Angiotensin type 1 receptor blocker restores podocyte potential to promote glomerular endothelial cell growth.

  2006cited by this paper
• Regression of existing glomerulosclerosis by inhibition of aldosterone.

  2005cited by this paper
• Factor XIIIA transglutaminase crosslinks AT1 receptor dimers of monocytes at the onset of atherosclerosis.

  2004cited by this paper
• A simplified method for HPLC determination of creatinine in mouse serum.

  2004cited by this paper
• Angiotensin II Amplifies Macrophage-Driven Atherosclerosis

  2004cited by this paper
• C-Reactive Protein Accelerates the Progression of Atherosclerosis in Apolipoprotein E–Deficient Mice

  2004cited by this paper
• Absence of angiotensin II type 1 receptor in bone marrow-derived cells is detrimental in the evolution of renal fibrosis.

  2002cited by this paper
• Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death.

  2002cited by this paper
• Silica-induced apoptosis in murine macrophage: involvement of tumor necrosis factor-alpha and nuclear factor-kappaB activation.

  2002cited by this paper
• Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages.

  2001cited by this paper
• Oxidative stress increases the expression of the angiotensin-II receptor type 1 in mouse peritoneal macrophages.

  2001cited by this paper
• Preactivated monocytes from hypertensive patients as a factor for atherosclerosis?

  2001cited by this paper
• Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators.

  2000cited by this paper
• Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.

  2000cited by this paper
• Biochemical Characterization of Endogenously Formed Eosinophilic Crystals in the Lungs of Mice*

  2000cited by this paper
• Immunol. Cell Biol.

  1995cited by this paper
• Prevention of atherosclerosis in apolipoprotein E-deficient mice by bone marrow transplantation

  1995cited by this paper
• Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.

  1992cited by this paper

• Progression of Kidney Fibrosis after Sepsis: The Underestimated Role of Resident Macrophages and Recruited Monocytes.

  2025cites this paper
• Iron, lipid peroxidation and ferroptosis play pathogenic roles in atherosclerosis.

  2024cites this paper
• Defective macrophage efferocytosis in advanced atherosclerotic plaque and mitochondrial therapy.

  2024cites this paper
• Modulator Effect of AT1 Receptor Knockdown on THP-1 Macrophage Proinflammatory Activity

  2024cites this paper
• Hypotensive drugs mitigate the high-sodium diet-induced pro-inflammatory activation of mouse macrophages in vivo.

  2024cites this paper
• Targeting Macrophages: Therapeutic Approaches in Diabetic Kidney Disease

  2024cites this paper
• A Review on the Role of Inflammation in Coronavirus Disease.

  2024cites this paper
• Role of Angiotensin II in Non-Alcoholic Steatosis Development.

  2024cites this paper
• Role of Angiotensin II in Cardiovascular Diseases: Introducing Bisartans as a Novel Therapy for Coronavirus 2019

  2023cites this paper
• Angiotensin II type 1a receptor deficiency alleviates muscle atrophy after denervation

  2023cites this paper
• A potential role of NFIL3 in atherosclerosis.

  2023cites this paper
• Reversal of aging-associated increase in myelopoiesis and expression of alarmins by angiotensin-(1–7)

  2023cites this paper
• RAGE pathway activation and function in chronic kidney disease and COVID-19

  2022cites this paper
• Role of Rho-kinase Inhibitor and hrsACE2 in COVID-19 Patients Management

  2022cites this paper
• Hepatoprotective effect of hydroalcoholic extract from root of Sechium edule (Jacq.) Sw. over hepatic injury induced by chronic application of angiotensin II

  2022influential citation
• Defective efferocytosis of vascular cells in heart disease

  2022cites this paper
• The Impaired Mechanism and Facilitated Therapies of Efferocytosis in Atherosclerosis

  2022cites this paper
• The future Landscape of macrophage research in cardiovascular disease: a bibliometric analysis.

  2022cites this paper
• Myeloid Angiotensin II Type 1 Receptor Mediates Macrophage Polarization and Promotes Vascular Injury in DOCA/Salt Hypertensive Mice

  2022cites this paper
• Concomitant Medication Effects on Immune Checkpoint Inhibitor Efficacy and Toxicity

  2022cites this paper
• Signaling cascades in the failing heart and emerging therapeutic strategies

  2022cites this paper
• Immunomodulatory Therapeutic Effects of Curcumin on M1 / M2 Macrophage polarization in Inflammatory Diseases.

  2022cites this paper
• Dynamics of vegetative, insomnia and neuropsychological manifestations during the treatment of post-COVID syndrome

  2022cites this paper
• Myeloid cells, tissue homeostasis, and anatomical barriers as innate immune effectors in arterial hypertension

  2021cites this paper
• Roles of Macrophages in Atherogenesis

  2021cites this paper
• Twist1 regulates macrophage plasticity to promote renal fibrosis through galectin-3

  2021cites this paper
• COVID-19 as a cause of chronic pulmonary hypertension: pathophysiological rationale and potential of instrumental investigations

  2021cites this paper
• Multiple-organ failure in patients with severe coronavirus disease (COVID-19)

  2021cites this paper
• A hitchhiker's guide through the COVID-19 galaxy

  2021cites this paper
• AT1R Regulates Macrophage Polarization Through YAP and Regulates Aortic Dissection Incidence

  2021cites this paper
• Endothelial Senescence and Chronic Fatigue Syndrome, a COVID-19 Based Hypothesis

  2021cites this paper
• The renin-angiotensin system and specifically angiotensin-converting enzyme 2 as a potential therapeutic target in SARS-CoV-2 infections

  2021cites this paper
• Regulation of Monocytes/Macrophages by the Renin–Angiotensin System in Diabetic Nephropathy: State of the Art and Results of a Pilot Study

  2021cites this paper
• Azithromycin: Immunomodulatory and antiviral properties for SARS-CoV-2 infection

  2021cites this paper
• Protective effects of natural products against drug-induced nephrotoxicity: a review in recent years.

  2021cites this paper
• Scientific hypothesis and rational pharmacological for the use of sacubitril/valsartan in cardiac damage caused by COVID-19

  2021cites this paper
• SIRT1 promotes macrophage polarization to enhance efferocytosis by regulating TXNIP/NLRP3 inflammasome pathway

  2021cites this paper
• The Role of Renin-Angiotensin-Aldosterone System in the Heart and Lung: Focus on COVID-19

  2021cites this paper
• Scientific Hypothesis for Treatment of COVID‐19′s Lung Lesions by Adjusting ACE/ACE2 Imbalance

  2021cites this paper
• Impact of Cardiovascular Diseases on COVID-19: A Systematic Review

  2021influential citation
• Potential Mechanisms and Effects of Efferocytosis in Atherosclerosis

  2021cites this paper
• Drugs acting on the renin–angiotensin system and SARS-CoV-2

  2021cites this paper
• Renin-Angiotensin System and Coronavirus Disease 2019: A Narrative Review

  2020cites this paper
• ACE2 at the centre of COVID-19 from paucisymptomatic infections to severe pneumonia

  2020cites this paper
• The pivotal link between ACE2 deficiency and SARS-CoV-2 infection

  2020cites this paper
• Are losartan and imatinib effective against SARS-CoV2 pathogenesis? A pathophysiologic-based in silico study

  2020cites this paper
• Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated kidney, eye and vessel injury

  2020cites this paper
• Correlation between renin-angiotensin system and Severe Acute Respiratory Syndrome Coronavirus 2 infection: What do we know?

  2020cites this paper
• Sympathetic activation: a potential link between comorbidities and COVID‐19

  2020cites this paper
• The potential role of the carotid body in COVID-19

  2020cites this paper
• Role of Interleukin-23/Interleukin-17 Axis in T-Cell Mediated Actions in Hypertension.

  2020cites this paper
• COVID-19 and multiorgan failure: A narrative review on potential mechanisms

  2020cites this paper
• The role of renin-angiotensin system and angiotensin-converting enzyme 2 (ACE2) in the development and course of viral infection COVID-19 in patients with diabetes mellitus

  2020cites this paper
• Angiotensin-converting enzyme (ACE) inhibitor prescription affects non-small-cell lung cancer (NSCLC) patients response to PD-1/PD-L1 immune checkpoint blockers

  2020cites this paper
• Uremic Toxin-Related Systemic Disorders

  2020cites this paper
• Does Virus-Receptor Interplay Influence Human Coronaviruses Infection Outcome?

  2020cites this paper
• SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function.

  2020cites this paper
• COVID-19, interleukin-6, androgen receptor and the adipose organ: what are the possible targets of this association?

  2020cites this paper
• Critical Determinants of Cytokine Storm and Type I Interferon Response in COVID-19 Pathogenesis

  2020cites this paper
• The Renin-Angiotensin-Aldosterone System in Coronavirus-19 Disease Pathogenesis: Extracting the Devil in the Details.

  2020cites this paper
• COVID-19

  2020cites this paper
• Hypertensive urgencies and emergencies: Misconceptions and pitfalls.

  2019cites this paper
• Angiotensin II and angiotensin 1–7: which is their role in atrial fibrillation?

  2019cites this paper
• Angiotensin II deteriorates advanced atherosclerosis by promoting MerTK cleavage and impairing efferocytosis through the AT1R/ROS/p38 MAPK/ADAM17 pathway

  2019cites this paper
• Preclinical Models of Dystrophic Cardiomyopathy and Therapies for the Dystrophic Heart

  2019cites this paper
• Acute AT1R blockade prevents isoproterenol-induced injury in mdx hearts.

  2019cites this paper
• Activation of Bone Marrow-Derived Cells Angiotensin (Ang) II Type 1 Receptor by Ang II Promotes Atherosclerotic Plaque Vulnerability

  2018cites this paper
• Cell-intrinsic sphingosine kinase 2 promotes macrophage polarization and renal inflammation in response to unilateral ureteral obstruction

  2018cites this paper
• Molecular mechanisms underlying uremic toxin-related systemic disorders in chronic kidney disease: focused on β2-microglobulin-related amyloidosis and indoxyl sulfate-induced atherosclerosis—Oshima Award Address 2016

  2018cites this paper
• Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated

  2018cites this paper
• AT2R Activation Prevents Microglia Pro-inflammatory Activation in a NOX-Dependent Manner: Inhibition of PKC Activation and p47phox Phosphorylation by PP2A

  2018cites this paper
• Preview : Published ahead of advance online publication Macrophage polarization and function : New prospects for fibrotic disease

  2017cites this paper
• Multifactorial Immune Cell-Based Development of Heart Failure

  2017cites this paper
• Cellular distribution and interaction between extended renin-angiotensin-aldosterone system pathways in atheroma.

  2017cites this paper
• Macrophage complexity in human atherosclerosis: opportunities for treatment?

  2017cites this paper
• Perivascular Adipose Tissue Angiotensin II Type 1 Receptor Promotes Vascular Inflammation and Aneurysm Formation

  2017cites this paper
• EVIDENCE THAT EFFEROCYTOSIS IS IMPAIRED IN ATHEROSCLEROSIS

  2017cites this paper
• TRPA1 receptor is upregulated in human oral lichen planus.

  2017cites this paper
• Macrophage polarization and function: new prospects for fibrotic disease

  2017cites this paper
• Calcitriol reduces kidney development disorders in rats provoked by losartan administration during lactation

  2017cites this paper
• The Role of Efferocytosis in Atherosclerosis

  2017cites this paper
• ACE2/Ang 1-7 axis: A critical regulator of epicardial adipose tissue inflammation and cardiac dysfunction in obesity

  2016cites this paper
• The macrophage and its related cholesterol efflux as a HDL function index in atherosclerosis.

  2016cites this paper
• Interactions Between the Immune and the Renin–Angiotensin Systems in Hypertension

  2016cites this paper
• Extracellular vesicles as mediators of vascular inflammation in kidney disease.

  2016cites this paper
• Reconfiguration of NKT Cell Subset Compartment Is Associated with Plaque Development in Patients with Carotid Artery Stenosis

  2016cites this paper
• Macrophages activate iNOS signaling in adventitial fibroblasts and contribute to adventitia fibrosis.

  2016cites this paper
• Curcumin alleviates renal dysfunction and suppresses inflammation by shifting from M1 to M2 macrophage polarization in daunorubicin induced nephrotoxicity in rats.

  2016cites this paper
• Angiotensin II alters the expression of duodenal iron transporters, hepatic hepcidin, and body iron distribution in mice

  2015cites this paper
• Stimulation of the Angiotensin II AT2 Receptor is Anti-inflammatory in Human Lipopolysaccharide-Activated Monocytic Cells

  2015cites this paper
• Increased Proinflammatory Cytokine Production and Decreased Cholesterol Efflux Due to Downregulation of ABCG1 in Macrophages Exposed to Indoxyl Sulfate

  2015cites this paper
• Bone marrow angiotensin AT2 receptor deficiency aggravates atherosclerosis development by eliminating macrophage liver X receptor-mediated anti-atherogenic actions

  2015cites this paper
• Complement-Mediated Macrophage Polarization in Perivascular Adipose Tissue Contributes to Vascular Injury in Deoxycorticosterone Acetate–Salt Mice

  2015cites this paper
• High Fat High Cholesterol Diet (Western Diet) Aggravates Atherosclerosis, Hyperglycemia and Renal Failure in Nephrectomized LDL Receptor Knockout Mice: Role of Intestine Derived Lipopolysaccharide

  2015influential citation
• ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity

  2015cites this paper
• Short-Term Treatment with an Angiotensin II Receptor Blocker Prevents Necrotic Core Formation by Inhibiting Oxidative Stress-Mediated Apoptosis in Macrophages

  2015cites this paper
• Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.

  2015cites this paper
• Uso de ferramentas de bioinformática na análise da expressão de genes antioxidantes e de genes dos fenótipos M1 e M2 em aterosclerose

  2014cites this paper
• Angiotensin IV is Induced in Experimental Autoimmune Encephalomyelitis but Fails to Influence the Disease

  2014cites this paper
• Increased Circulatory Lipopolysaccharide From a High Fat Diet Aggravates Inflammation and Exacerbates Renal Failure

  2014cites this paper