Respiratory gases and the regulation of transcription

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Experimental Physiology

• Publication date

  2016-08-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1113/EP085715PMID 27474261
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

  2016cited by this paper
• Identification of Drosophila Zfh2 as a Mediator of Hypercapnic Immune Regulation by a Genome-Wide RNA Interference Screen

  2016cited by this paper
• Hypercapnia Suppresses the HIF-dependent Adaptive Response to Hypoxia*

  2016cited by this paper
• Hypercapnic acidosis attenuates pulmonary epithelial stretch-induced injury via inhibition of the canonical NF-κB pathway

  2016cited by this paper
• Sirt1: Role Under the Condition of Ischemia/Hypoxia

  2016cited by this paper
• The tumour hypoxia induced non-coding transcriptome.

  2016influential reference
• Focused Screening Identifies Evoxine as a Small Molecule That Counteracts CO2-Induced Immune Suppression

  2016cited by this paper
• Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.

  2016influential reference
• The hypoxia‐inducible miR‐429 regulates hypoxia‐inducible factor‐1α expression in human endothelial cells through a negative feedback loop

  2015cited by this paper
• Effect of Therapeutic Hypercapnia on Inflammatory Responses to One-lung Ventilation in Lobectomy Patients

  2015cited by this paper
• Hypoxia and STAT3 signalling interactions regulate pro-inflammatory pathways in rheumatoid arthritis.

  2015cited by this paper
• REST mediates resolution of HIF-dependent gene expression in prolonged hypoxia

  2015cited by this paper
• Modifying the maker: Oxygenases target ribosome biology

  2015cited by this paper
• High CO2 Levels Cause Skeletal Muscle Atrophy via AMP-activated Kinase (AMPK), FoxO3a Protein, and Muscle-specific Ring Finger Protein 1 (MuRF1)*

  2015cited by this paper
• Hypercapnic acidosis prolongs survival of skin allografts.

  2015cited by this paper
• Hypoxia activates IKK–NF-κB and the immune response in Drosophila melanogaster

  2014cited by this paper
• Hypo- and hypercapnia predict mortality in oxygen-dependent chronic obstructive pulmonary disease: a population-based prospective study

  2014influential reference
• Non-invasive positive pressure ventilation for the treatment of severe stable chronic obstructive pulmonary disease: a prospective, multicentre, randomised, controlled clinical trial.

  2014cited by this paper
• Transcriptional Network Analysis in Muscle Reveals AP-1 as a Partner of PGC-1α in the Regulation of the Hypoxic Gene Program

  2014cited by this paper
• Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase

  2014cited by this paper
• DEC1/STRA13/SHARP2 and DEC2/SHARP1 coordinate physiological processes, including circadian rhythms in response to environmental stimuli.

  2014cited by this paper
• Structural and functional analysis of the related transcriptional enhancer factor-1 and NF-κB interaction.

  2014cited by this paper
• FoxO3a Modulates Hypoxia Stress Induced Oxidative Stress and Apoptosis in Cardiac Microvascular Endothelial Cells

  2013cited by this paper
• Early growth response gene-1 and hypoxia-inducible factor-1α affect tumor metastasis via regulation of tissue factor

  2013cited by this paper
• Hypoxia alters the epigenetic profile in cultured human placental trophoblasts

  2013cited by this paper
• cAMP-response Element-binding Protein (CREB) and NF-κB Transcription Factors Are Activated during Prolonged Hypoxia and Cooperatively Regulate the Induction of Matrix Metalloproteinase MMP1*

  2013cited by this paper
• Carbon dioxide-sensing in organisms and its implications for human disease

  2013influential reference
• Protective Effect of Hypercapnic Acidosis in Ischemia-Reperfusion Lung Injury Is Attributable to Upregulation of Heme Oxygenase-1

  2013cited by this paper
• Regulation of IL-1β–induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways

  2013cited by this paper
• PERK/eIF2α signaling protects therapy resistant hypoxic cells through induction of glutathione synthesis and protection against ROS

  2013cited by this paper
• Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B.

  2013cited by this paper
• MYC Degradation under Low O2 Tension Promotes Survival by Evading Hypoxia-Induced Cell Death

  2013cited by this paper
• Hypocapnia and hypercapnia are predictors for ICU admission and mortality in hospitalized patients with community-acquired pneumonia.

  2012cited by this paper
• The updated biology of hypoxia‐inducible factor

  2012cited by this paper
• An oxygen-regulated switch in the protein synthesis machinery

  2012cited by this paper
• Hypercapnia Induces Cleavage and Nuclear Localization of RelB Protein, Giving Insight into CO2 Sensing and Signaling*

  2012cited by this paper
• miR‐210: The Master Hypoxamir

  2012influential reference
• Chromatin as an oxygen sensor and active player in the hypoxia response

  2012cited by this paper
• C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes.

  2012cited by this paper
• HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

  2011cited by this paper
• Regulation of gene expression by carbon dioxide

  2011cited by this paper
• MicroRNA-155 Promotes Resolution of Hypoxia-Inducible Factor 1α Activity during Prolonged Hypoxia

  2011cited by this paper
• RTEF-1, an Upstream Gene of Hypoxia-inducible Factor-1α, Accelerates Recovery from Ischemia*

  2011cited by this paper
• FoxO3A promotes metabolic adaptation to hypoxia by antagonizing Myc function

  2011cited by this paper
• Roles of the human hypoxia-inducible factor (HIF)-3α variants in the hypoxia response

  2011cited by this paper
• Reciprocal influence of the p53 and the hypoxic pathways

  2011cited by this paper
• Congenital central hypoventilation syndrome in children.

  2011cited by this paper
• Hypoxia-inducible Factor-1α Enhances Haptoglobin Gene Expression by Improving Binding of STAT3 to the Promoter*

  2011cited by this paper
• An Intact Canonical NF-κB Pathway Is Required for Inflammatory Gene Expression in Response to Hypoxia

  2011cited by this paper
• The hypoxia-associated factor switches cells from HIF-1α- to HIF-2α-dependent signaling promoting stem cell characteristics, aggressive tumor growth and invasion.

  2011cited by this paper
• NF-κB Links CO2 Sensing to Innate Immunity and Inflammation in Mammalian Cells

  2010cited by this paper
• Normoxic destabilization of ATF‐4 depends on proteasomal degradation

  2010cited by this paper
• Mechanism of Hypoxia-Induced NF-κB

  2010cited by this paper
• Regulation of Cyr61/CCN1 expression by hypoxia through cooperation of c-Jun/AP-1 and HIF-1α in retinal vascular endothelial cells.

  2010cited by this paper
• Ancient atmospheres and the evolution of oxygen sensing via the hypoxia-inducible factor in metazoans.

  2010cited by this paper
• Placenta Growth Factor-induced Early Growth Response 1 (Egr-1) Regulates Hypoxia-inducible Factor-1α (HIF-1α) in Endothelial Cells*

  2010cited by this paper
• Task2 potassium channels set central respiratory CO2 and O2 sensitivity

  2010cited by this paper
• Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1α Enhances Hypoxic Gene Expression and Tumor Growth

  2009cited by this paper
• Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase.

  2009cited by this paper
• Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-κB dependent mechanism

  2009cited by this paper
• Elevated CO2 suppresses specific Drosophila innate immune responses and resistance to bacterial infection

  2009cited by this paper
• The Role of NF‐κB in Hypoxia‐Induced Gene Expression

  2009cited by this paper
• Stimulation of Mammalian G-protein-responsive Adenylyl Cyclases by Carbon Dioxide

  2009cited by this paper
• Egr-1 is not upregulated in response to hypoxic and oxygenation conditions in human glioblastoma in vitro.

  2009cited by this paper
• New regulators of NF-κB in inflammation

  2008cited by this paper
• Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway.

  2008cited by this paper
• Hypoxia selectively activates the CREB family of transcription factors in the in vivo lung.

  2008cited by this paper
• STAT3 inhibits the degradation of HIF-1α by pVHL-mediated ubiquitination

  2008cited by this paper
• Regulation of gene expression by hypoxia.

  2008influential reference
• The hydroxylase inhibitor dimethyloxalylglycine is protective in a murine model of colitis.

  2008cited by this paper
• STAT3 inhibits the degradation of HIF-1alpha by pVHL-mediated ubiquitination.

  2008cited by this paper
• Carotid body oxygen sensing

  2008cited by this paper
• The angiopoietin‐2 gene of endothelial cells is up‐regulated in hypoxia by a HIF binding site located in its first intron and by the central factors GATA‐2 and Ets‐1

  2008influential reference
• Loss of c/EBP-beta activity promotes the adaptive to apoptotic switch in hypoxic cortical neurons.

  2008cited by this paper
• Carrot and stick: HIF-α engages c-Myc in hypoxic adaptation

  2008cited by this paper
• HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity.

  2007influential reference
• Molecular regulation of the PAI-1 gene by hypoxia: contributions of Egr-1, HIF-1alpha, and C/EBPalpha.

  2007cited by this paper
• FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2.

  2007influential reference
• Hypoxia and regulation of messenger RNA translation.

  2007cited by this paper
• Molecular regulation of the PAI‐1 gene by hypoxia: contributions of Egr‐1, HIF‐1 α, and C/EBPα

  2007cited by this paper
• Identification of Purα as a New Hypoxia Response Factor Responsible for Coordinated Induction of the β2 Integrin Family1

  2007cited by this paper
• Chronic high inspired CO2 decreases excitability of mouse hippocampal neurons

  2007cited by this paper
• Cell-specific regulation of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha stabilization and transactivation in a graded oxygen environment.

  2006cited by this paper
• Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms.

  2006cited by this paper
• Prolyl hydroxylase-1 negatively regulates IkappaB kinase-beta, giving insight into hypoxia-induced NFkappaB activity.

  2006cited by this paper
• Phosphorylation of cAMP response element binding protein (CREB) as a marker of hypoxia in pituitary adenoma

  2006cited by this paper
• Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

  2006cited by this paper
• Hypoxia induces epithelial amphiregulin gene expression in a CREB-dependent manner.

  2006cited by this paper
• Cell-specific Regulation of Hypoxia-inducible Factor (HIF)-1α and HIF-2α Stabilization and Transactivation in a Graded Oxygen Environment*

  2006cited by this paper
• The phosphorylation status of PAS‐B distinguishes HIF‐1α from HIF‐2α in NBS1 repression

  2006cited by this paper
• Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition

  2006cited by this paper
• Effect of carbon dioxide on neonatal mouse lung: a genomic approach.

  2006cited by this paper
• Enhanced phosphorylation of cyclic AMP response element binding protein in the brain of mice following repetitive hypoxic exposure.

  2006cited by this paper
• Dual regulation of macrophage migration inhibitory factor (MIF) expression in hypoxia by CREB and HIF-1.

  2006cited by this paper
• Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity

  2006cited by this paper
• The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression.

  2006cited by this paper
• The interaction between HIF-1 and AP-1 transcription factors in response to low oxygen.

  2005cited by this paper
• HIF-1α and p53: the ODD couple?

  2005cited by this paper
• HIF-1alpha and p53: the ODD couple?

  2005cited by this paper
• Hypoxia-responsive transcription factors

  2005influential reference

• Conditional Stabilization of the Hypoxia-Inducible Factor HIF1α - Photoswitchable Stapled Peptides Prevent Elongin BC Mediated Degradation.

  2025cites this paper
• Hypoxia reduces SLC27A5 to promote hepatocellular carcinoma proliferation by repressing HNF4A.

  2025cites this paper
• Leptin signaling in the dorsomedial hypothalamus couples breathing and metabolism in obesity

  2023cites this paper
• Elements of Sleep Breathing and Sleep-Deprivation Physiology in the Context of Athletic Performance

  2022cites this paper
• Microenvironmental modulation of the intestinal epithelial barrier

  2022cites this paper
• Hypoxia Inducible Factor 1A Supports a Pro-Fibrotic Phenotype Loop in Idiopathic Pulmonary Fibrosis

  2021cites this paper
• Carbon dioxide levels in neonates: what are safe parameters?

  2021cites this paper
• Carbon dioxide-dependent signal transduction in mammalian systems

  2021cites this paper
• Use of dry carbonic acid gas baths to correct human biological age

  2020cites this paper
• Mechanisms and consequences of oxygen- and carbon dioxide-sensing in mammals.

  2020influential citation
• Protein Hydroxylation by Hypoxia-Inducible Factor (HIF) Hydroxylases: Unique or Ubiquitous?

  2019cites this paper
• Importance of microclimate conditions and CO2control in educational buildings: a case study

  2018cites this paper
• Minocycline alters expression of inflammatory markers in autonomic brain areas and ventilatory responses induced by acute hypoxia

  2018cites this paper
• A time of change: out with the old, in with the new

  2017cites this paper
• α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury

  2017cites this paper
• Determinants of hypoxia-inducible factor activity in the intestinal mucosa.

  2017cites this paper
• Carbon dioxide-dependent regulation of NF-κB family members RelB and p100 gives molecular insight into CO2-dependent immune regulation

  2017cites this paper
• Physiological gases in health and disease – key regulatory factors, not just a lot of hot air

  2017cites this paper