Isoflurane Provides Long-term Protection against Focal Cerebral Ischemia in the Rat

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Anesthesiology

• Publication date

  2007-01-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/00000542-200701000-00017PMID 17197850
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The Copenhagen Stroke Study

  2007cited by this paper
• The Combination of Isoflurane and Caspase 8 Inhibition Results in Sustained Neuroprotection in Rats Subject to Focal Cerebral Ischemia

  2006cited by this paper
• The Long-Term Effect of Sevoflurane on Neuronal Cell Damage and Expression of Apoptotic Factors After Cerebral Ischemia and Reperfusion in Rats

  2006cited by this paper
• Neuroprotective effects of anesthetic agents

  2005cited by this paper
• Adenosine A(1) receptor antagonist and mitochondrial ATP-sensitive potassium channel blocker attenuate the tolerance to focal cerebral ischemia in rats.

  2004cited by this paper
• Ischemic penumbra in a model of reversible middle cerebral artery occlusion in the rat

  2004influential reference
• Perioperative neuroprotection: are we asking the right questions?

  2004cited by this paper
• Effects of Isoflurane Versus Fentanyl–Nitrous Oxide Anesthesia on Long-term Outcome from Severe Forebrain Ischemia in the Rat

  2004cited by this paper
• Intraischemic Nitrous Oxide Alters Neither Neurologic Nor Histologic Outcome: A Comparison with Dizocilpine

  2004cited by this paper
• Adenosine A1 Receptor Antagonist and Mitochondrial ATP-Sensitive Potassium Channel Blocker Attenuate the Tolerance to Focal Cerebral Ischemia in Rats

  2004cited by this paper
• Combination of Isoflurane and Caspase Inhibition Reduces Cerebral Injury in Rats Subjected to Focal Cerebral Ischemia

  2004cited by this paper
• Opening of Mitochondrial ATP-Sensitive Potassium Channels Is a Trigger of 3-Nitropropionic Acid–Induced Tolerance to Transient Focal Cerebral Ischemia in Rats

  2003cited by this paper
• Preconditioning with Isoflurane Produces Dose-Dependent Neuroprotection via Activation of Adenosine Triphosphate-Regulated Potassium Channels After Focal Cerebral Ischemia in Rats

  2003cited by this paper
• Isoflurane Prevents Delayed Cell Death in an Organotypic Slice Culture Model of Cerebral Ischemia

  2002cited by this paper
• Admission Body Temperature Predicts Long-Term Mortality After Acute Stroke: The Copenhagen Stroke Study

  2002cited by this paper
• Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.

  2002cited by this paper
• Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest.

  2002cited by this paper
• Cerebral microvascular pathology in aging and Alzheimer's disease.

  2001cited by this paper
• Isoflurane Delays but Does Not Prevent Cerebral Infarction in Rats Subjected to Focal Ischemia

  1999influential reference
• Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats.

  1999cited by this paper
• Fentanyl does not increase brain injury after focal cerebral ischemia in rats.

  1999cited by this paper
• Desflurane and isoflurane improve neurological outcome after incomplete cerebral ischaemia in rats.

  1999cited by this paper
• Relative Neuroprotective Effects of Dizocilpine and Isoflurane During Focal Cerebral Ischemia in the Rat

  1998cited by this paper
• Differential Effects of Anesthetic Agents on Outcome from Near‐complete but Not Incomplete Global Ischemia in the Rat

  1998cited by this paper
• Occurrence of potentially detrimental temperature alterations in hospitalized patients at risk for brain injury.

  1998cited by this paper
• Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia

  1997cited by this paper
• Very Delayed Infarction after Mild Focal Cerebral Ischemia: A Role for Apoptosis?

  1996influential reference
• Delayed postischemic hypothermia: a six month survival study using behavioral and histological assessments of neuroprotection.

  1996cited by this paper
• Delayed postischemic hypothermia: a six month survival study using behavioral and histological assessments of neuroprotection

  1995cited by this paper
• Halothane Reduces Focal Ischemic Injury in the Rat When Brain Temperature Is Controlled

  1995cited by this paper
• Intraischemic but Not Postischemic Brain Hypothermia Protects Chronically following Global Forebrain Ischemia in Rats

  1993cited by this paper
• Sevoflurane and Halothane Reduce Focal Ischemic Brain Damage in the Rat: Possibloe Influence on Thermoregulation

  1993cited by this paper
• A Semiautomated Method for Measuring Brain Infarct Volume

  1990cited by this paper
• Comparison of methohexital and isoflurane on neurologic outcome and histopathology following incomplete ischemia in rats.

  1990cited by this paper
• Reversible middle cerebral artery occlusion without craniectomy in rats.

  1989influential reference
• Neurologic Outcome in Rats Following Incomplete Cerebral Ischemia during Halothane, Isoflurane, or N2O

  1988cited by this paper
• A Comparison of the Cerebral Protective Effects of Isoflurane and Barbiturates during Temporary Focal Ischemia in Primates

  1987cited by this paper
• Small Differences in Intraischemic Brain Temperature Critically Determine the Extent of Ischemic Neuronal Injury

  1987cited by this paper
• The Effect of Isoflurane on Neuronal Necrosis Following Near‐complete Forebrain Ischemia in the Rat

  1986cited by this paper
• Cerebral Protection by Isoflurane During Hypoxemia or Ischemia

  1984cited by this paper
• Cerebral Protection by Isoflurane during Hypoxemia or Ischemia

  1982cited by this paper
• Barbiturate Protection in Acute Focal Cerebral Ischemia

  1974cited by this paper
• Effects of Halothane on Regional Cerebral Blood Flow in Experimental Focal Ischemia

  1973cited by this paper

• Predictive Utility of Cerebral Blood Flow Transients in Experimental Stroke

  2026cites this paper
• Estimating blood oxygen saturation through susceptibility source separation: A new standpoint on quantitative BOLD models

  2025cites this paper
• Research Progress of Isoflurane in Alleviating Cerebral Ischemia/Reperfusion Injury.

  2025cites this paper
• Veterinary medical care in rodent models of stroke: Pitfalls and refinements to balance quality of science and animal welfare.

  2025influential citation
• Stroke and translational research - review of experimental models with a focus on awake ischaemic induction and anaesthesia.

  2023cites this paper
• Distinctions between the Koizumi and Zea Longa methods for middle cerebral artery occlusion (MCAO) model: a systematic review and meta-analysis of rodent data

  2023cites this paper
• Effects of isoflurane and xylazine on inducing cerebral ischemia by the model of middle cerebral artery occlusion in mice

  2023cites this paper
• Connectome-based prediction of functional impairment in experimental stroke models

  2023cites this paper
• The Impact of General Anesthesia on Redox Stability and Epigenetic Inflammation Pathways: Crosstalk on Perioperative Antioxidant Therapy

  2022cites this paper
• Anesthesia for acute stroke

  2022cites this paper
• Isoflurane Attenuates Cerebral Ischaemia–Reperfusion Injury via the TLR4-NLRP3 Signalling Pathway in Diabetic Mice

  2022cites this paper
• Perioperative stroke: A perspective on challenges and opportunities for experimental treatment and diagnostic strategies

  2022cites this paper
• Salvinorin A for Stroke Rescue Purposes

  2022cites this paper
• Post-ischemia common carotid artery occlusion worsens memory loss, but not sensorimotor deficits, in long-term survived stroke mice.

  2022cites this paper
• Inhaled sedation in the intensive care unit.

  2022cites this paper
• Cortical Spreading Depolarization, Blood Flow, and Cognitive Outcomes in a Closed Head Injury Mouse Model of Traumatic Brain Injury

  2022cites this paper
• Non-invasive diffuse optical neuromonitoring during cardiopulmonary resuscitation predicts return of spontaneous circulation

  2021cites this paper
• Targeting focal ischemic and hemorrhagic stroke neuroprotection: Current prospects for local hypothermia

  2021cites this paper
• Use of volatile agents for sedation in the intensive care unit: A national survey in France

  2020cites this paper
• Temporal Progression of Excitotoxic Calcium Following Distal Middle Cerebral Artery Occlusion in Freely Moving Mice

  2020cites this paper
• Antithrombotic Agents for tPA‐Induced Cerebral Hemorrhage: A Systematic Review and Meta‐Analysis of Preclinical Studies

  2020cites this paper
• Isoflurane reduces septic neuron injury by HO-1-mediated abatement of inflammation and apoptosis

  2020cites this paper
• Progress in modelling of brain dynamics during anaesthesia and the role of sleep-wake circuitry.

  2020cites this paper
• Dynamics of isoflurane-induced vasodilation and blood flow of cerebral vasculature revealed by multi-exposure speckle imaging

  2020cites this paper
• Distinctive effect of anesthetics on the effect of limb remote ischemic postconditioning following ischemic stroke

  2020cites this paper
• Immunomodulatory approaches after experimental ischemic stroke

  2020cites this paper
• Anesthesia and Neurodegeneration

  2019cites this paper
• Mass Spectrometry Imaging (MSI) of Fresh Bones using Infrared Matrix-Assisted Laser Desorption Electrospray Ionization (IR-MALDESI).

  2019cites this paper
• Argon Inhalation for 24 Hours After Onset of Permanent Focal Cerebral Ischemia in Rats Provides Neuroprotection and Improves Neurologic Outcome.

  2019cites this paper
• Ischemic stroke reduces bone perfusion and alters osteovascular structure

  2019cites this paper
• Sevoflurane postconditioning improves the spatial learning and memory impairments induced by hemorrhagic shock and resuscitation through suppressing IRE1α-caspase-12-mediated endoplasmic reticulum stress pathway.

  2018cites this paper
• Refinement of embolic stroke model in rats: Effect of post-embolization anesthesia duration on arterial blood pressure, cerebral edema and mortality.

  2018cites this paper
• Effect of laser Doppler flowmetry and occlusion time on outcome variability and mortality in rat middle cerebral artery occlusion: inconclusive results

  2018cites this paper
• Sevoflurane reduces ischemic brain injury in rats with diet and streptozotocin-induced diabetes

  2018cites this paper
• Neuroanatomy- and Pathology-Based Functional Examinations of Experimental Stroke in Rats: Development and Validation of a New Behavioral Scoring System

  2018cites this paper
• Repeated isoflurane in adult male mice leads to acute and persistent motor decrements with long‐term modifications in corpus callosum microstructural integrity

  2018cites this paper
• Duration of isoflurane-based surgical anesthesia determines severity of brain injury and neurological deficits after a transient focal ischemia in young adult rats.

  2017influential citation
• Reconceptualising stroke research to inform the question of anaesthetic neurotoxicity

  2017cites this paper
• Comparison of the cerebroprotective effect of inhalation anaesthesia and total intravenous anaesthesia in patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

  2017cites this paper
• Intraluminal spindle-shaped-head suture induced occlusion of middle cerebral artery in the rats

  2017cites this paper
• Challenging Topics in Neuroanesthesia and Neurocritical Care

  2017cites this paper
• Isoflurane decreases proliferation and differentiation, but none of the effects persist in human embryonic stem cell-derived neural progenitor cells

  2017cites this paper
• Effect of propofol, sevoflurane, and isoflurane on postoperative cognitive dysfunction following laparoscopic cholecystectomy in elderly patients: A randomized controlled trial.

  2017cites this paper
• Sedation in Neurocritical Units

  2017cites this paper
• Beneficial Effects of Delayed P7C3-A20 Treatment After Transient MCAO in Rats

  2017cites this paper
• Neuroprotection provided by isoflurane pre-conditioning and post-conditioning

  2017cites this paper
• Isoflurane Use in the Treatment of Super-Refractory Status Epilepticus is Associated with Hippocampal Changes on MRI

  2017cites this paper
• Hydrogen sulfide attenuates isoflurane-induced neuroapoptosis and cognitive impairment in the developing rat brain

  2017cites this paper
• Isoflurane Impairs Motor Function Recovery by Increasing Neuroapoptosis and Degeneration During Spinal Ischemia–Reperfusion Injury in Rats

  2017cites this paper
• A Novel Model of Transient Occlusion of the Middle Cerebral Artery in Awake Mice.

  2016cites this paper
• Anesthesia in Experimental Stroke Research

  2016cites this paper
• Exposure of isoflurane-treated cells to hyperoxia decreases cell viability and activates the mitochondrial apoptotic pathway.

  2016cites this paper
• Isoflurane enhances the malignant potential of glioblastoma stem cells by promoting their viability, mobility in vitro and migratory capacity in vivo.

  2016cites this paper
• Translational Hurdles in Stroke Recovery Studies

  2016cites this paper
• Isoflurane preconditioning protects rat brain from ischemia reperfusion injury via up-regulating the HIF-1α expression through Akt/mTOR/s6K activation.

  2016cites this paper
• 16. Brain Injury-Neuroprotection

  2016cites this paper
• The Effects of Mild Concussions and Pomegranates on Behavior

  2016cites this paper
• Research Paper: Optimization of Transient Focal Cerebral Ischemia Model by Middle Cerebral Artery Occlusion

  2016cites this paper
• Local O2 Balance in Cerebral Ischemia-Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia.

  2015cites this paper
• A sensory stimulation-based collateral therapeutic for ischemic stroke: new insights and limitations

  2015cites this paper
• Into the deep end: a look at the functional changes of neuronal pathways in the deeply anesthetized state.

  2015cites this paper
• Anesthetics and cerebral protection in patients undergoing carotid endarterectomy.

  2015cites this paper
• [General anesthetics as a factor of effective neuroprotection in ischemic stroke models].

  2015cites this paper
• Neuroprotective strategies for transient focal cerebral ischemia : an experimental model

  2015cites this paper
• A blinded randomized assessment of laser Doppler flowmetry efficacy in standardizing outcome from intraluminal filament MCAO in the rat.

  2015cites this paper
• Sustained Functional Improvement by Hepatocyte Growth Factor-Like Small Molecule BB3 after Focal Cerebral Ischemia in Rats and Mice

  2015cites this paper
• Neurodevelopmental implications of the general anesthesia in neonate and infants.

  2015cites this paper
• Neuroprotective gases--fantasy or reality for clinical use?

  2014cites this paper
• Induction of ischemic stroke in awake freely moving mice reveals that isoflurane anesthesia can mask the benefits of a neuroprotection therapy

  2014cites this paper
• A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain

  2014cites this paper
• Anaesthetic management of the patient with acute ischaemic stroke.

  2014cites this paper
• Anesthetic neuroprotection: antecedents and an appraisal of preclinical and clinical data quality.

  2014cites this paper
• Isoflurane but Not Sevoflurane or Desflurane Aggravates Injury to Neurons In Vitro and In Vivo via p75NTR-NF-ĸB Activation

  2014cites this paper
• Inhibition of brain ischemia-caused notch activation in microglia may contribute to isoflurane postconditioning-induced neuroprotection in male rats.

  2014cites this paper
• Anesthetic Preconditioning Inhibits Isoflurane-Mediated Apoptosis in the Developing Rat Brain

  2014cites this paper
• Dual effects of neuroprotection and neurotoxicity by general anesthetics: role of intracellular calcium homeostasis.

  2013cites this paper
• Dual Effects of Isoflurane on Proliferation, Differentiation, and Survival in Human Neuroprogenitor Cells

  2013cites this paper
• Role of suture diameter and vessel insertion position in the establishment of the middle cerebral artery occlusion rat model

  2013cites this paper
• Early stimulation treatment provides complete sensory‐induced protection from ischemic stroke under isoflurane anesthesia

  2013cites this paper
• General anesthetics in brain injury: friends or foes?

  2013cites this paper
• Microarray Analyses of Genes Regulated by Isoflurane Anesthesia In Vivo: A Novel Approach to Identifying Potential Preconditioning Mechanisms

  2013cites this paper
• Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice.

  2013cites this paper
• A Combination of Sevoflurane Postconditioning and Albumin Increases Bcl-2 Expression After Transient Global Cerebral Ischemia Compared With Either Sevoflurane Postconditioning or Albumin Alone

  2013cites this paper
• Repetitive intraperitoneal caspase-3 inhibitor and anesthesia reduces neuronal damage

  2013cites this paper
• Acute and sustained isoflurane neuroprotection: The effect of culture age and duration of oxygen and glucose deprivation

  2013cites this paper
• Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat.

  2013cites this paper
• Exploring the role of tumor necrosis factor-stimulated gene 6 in experimental ischaemic stroke

  2013cites this paper
• General anesthetics: neuroprotective or neurotoxic?

  2013influential citation
• Effects of the Thioredoxin-1 Inhibitor PX-12 on Blood-Brain Barrier Permeability in the Early Stage of Focal Cerebral Ischemia

  2013cites this paper
• Anesthetic Protection of Neurons Injured by Hypothermia and Rewarming: Roles of Intracellular Ca2+ and Excitotoxicity

  2012cites this paper
• Long-term and spatial memory effects of selective β1-antagonists after transient focal ischaemia in rats.

  2012cites this paper
• Neuroprotective Effects of Remifentanil Against Transient Focal Cerebral Ischemia in Rats

  2012influential citation
• Are volatile anesthetics neuroprotective or neurotoxic?

  2012cites this paper
• Anesthetic management of patients with acute stroke.

  2012cites this paper
• Isoflurane Induces Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier in a Transdifferentiated Human Umbilical Vein Edothelial Cell Model

  2012cites this paper
• Simple model of forebrain ischemia in mouse.

  2012cites this paper
• Volatile isoflurane sedation in cerebrovascular intensive care patients using AnaConDa®: effects on cerebral oxygenation, circulation, and pressure

  2012cites this paper
• Neurotoxicity of general anesthetics: an update.

  2012cites this paper
• Xenon Neuroprotection in Experimental Stroke: Interactions with Hypothermia and Intracerebral Hemorrhage

  2012cites this paper
• Guidelines for Using Mouse Global Cerebral Ischemia Models

  2012cites this paper