Conversion of xanthine dehydrogenase to oxidase in ischemic rat tissues.

No abstract is available for this paper.

• Publication year

  1987

• Venue

  Journal of Clinical Investigation

• Publication date

  1987-06-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI112990PMID 3294898PMCID PMC424467
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of free radicals in ischemia-reperfusion injury to the liver.

  1986cited by this paper
• Ischemia-reperfusion injury: role of oxygen-derived free radicals.

  1986cited by this paper
• Xanthine oxidase: a critical mediator of myocardial injury during ischemia and reperfusion?

  1986cited by this paper
• The role of oxygen free radicals in mediating the reperfusion injury of cold-preserved ischemic kidneys.

  1985cited by this paper
• Ischemia and reperfusion-induced arrhythmias in the rat. Effects of xanthine oxidase inhibition with allopurinol.

  1984cited by this paper
• Canine Myocardial Reperfusion Injury: Its Reduction by the Combined Administration of Superoxide Dismutase and Catalase

  1984cited by this paper
• Effects of free radical scavengers on renal circulation after ischaemia in the rabbit.

  1983cited by this paper
• Ischemia-induced vascular changes: role of xanthine oxidase and hydroxyl radicals.

  1983cited by this paper
• Possible role for calmodulin in calcium paradox-induced heart failure.

  1983cited by this paper
• Ischemic injury in the cat small intestine: role of superoxide radicals.

  1982cited by this paper
• Calcium-dependent proteolytic activity in rat liver: identification of two proteases with different calcium requirements.

  1981cited by this paper
• Superoxide radicals in feline intestinal ischemia.

  1981cited by this paper
• Purification and properties of the NAD+-dependent (type D) and O2-dependent (type O) forms of rat liver xanthine dehydrogenase.

  1976cited by this paper
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding.

  1976cited by this paper
• Allopurinol and hypoxanthine pretreatment of canine kidney donors.

  1974cited by this paper
• A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase.

  1974cited by this paper
• Milk xanthine oxidase type D (dehydrogenase) and type O (oxidase). Purification, interconversion and some properties.

  1973cited by this paper
• The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme.

  1972cited by this paper
• Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

  1970cited by this paper
• Effect of allopurinol on hemorrhagic shock.

  1969cited by this paper

• A non-purine inhibitor of xanthine oxidoreductase mitigates adenosine triphosphate degradation under hypoxic conditions in mouse brain.

  2025cites this paper
• Oxidative stress and ferroptosis in diabetic cardiomyopathy: mechanistic interplay and therapeutic implications

  2025cites this paper
• Intestinal oxygen utilisation and cellular adaptation during intestinal ischaemia–reperfusion injury

  2024cites this paper
• Identification of a novel xanthine oxidoreductase inhibitor for hyperuricemia treatment with high efficacy and safety profile.

  2024cites this paper
• Novel Reversible Inhibitors of Xanthine Oxidase Targeting the Active Site of the Enzyme

  2023cites this paper
• Cardiovascular significance of adipose-derived adiponectin and liver-derived xanthine oxidoreductase in metabolic syndrome.

  2023cites this paper
• Attenuation Effect of Salvianolic Acid B on Testicular Ischemia-Reperfusion Injury in Rats

  2022cites this paper
• Increased plasma XOR activity induced by NAFLD/NASH and its possible involvement in vascular neointimal proliferation

  2021cites this paper
• Novel Experimental Therapies for Treatment of Pulmonary Arterial Hypertension

  2021cites this paper
• Gene Expression of Putative Pathogenicity-Related Genes in Verticillium dahliae in Response to Elicitation with Potato Extracts and during Infection Using Quantitative Real-Time PCR

  2021cites this paper
• Protein S-glutathionylation decreases superoxide/hydrogen peroxide production xanthine oxidoreductase.

  2021cites this paper
• Hepatic ischemia-reperfusion injury

  2020cites this paper
• Plasma xanthine oxidoreductase activity in Japanese patients with type 2 diabetes across hospitalized treatment

  2020cites this paper
• Nanocarrier-mediated antioxidant delivery for liver diseases

  2020influential citation
• Degree of blood pressure control and the risk of new-onset hyperuricemia in treated hypertensive patients

  2020cites this paper
• Targeting Mitochondria during Cold Storage to Maintain Proteasome Function and Improve Renal Outcome after Transplantation

  2020cites this paper
• Ospemifene displays broad-spectrum synergistic interactions with itraconazole through potent interference with fungal efflux activities

  2020cites this paper
• The Potential Role of Sestrin 2 in Liver Regeneration.

  2020cites this paper
• Shortage of Cellular ATP as a Cause of Diseases and Strategies to Enhance ATP

  2019cites this paper
• Xanthine oxidase is hyper‐active in Duchenne muscular dystrophy

  2018cites this paper
• Redox Regulation of Homeostasis and Proteostasis in Peroxisomes.

  2018cites this paper
• Maternal Allopurinol Prevents Cardiac Dysfunction in Adult Male Offspring Programmed by Chronic Hypoxia During Pregnancy

  2018cites this paper
• Redox-Dependent Calpain Signaling in Airway and Pulmonary Vascular Remodeling in COPD.

  2017cites this paper
• Pulmonary Vasculature Redox Signaling in Health and Disease

  2017influential citation
• Soluble Uric Acid Activates the NLRP3 Inflammasome

  2017cites this paper
• Development Of Chemical Tools To Investigate Protein S-Glutathionylation In Response To Metabolic Alteration

  2017cites this paper
• Antioxidant and proapoptotic effects of anthocyanins from bilberry extract in rats exposed to hepatotoxic effects of carbon tetrachloride.

  2016cites this paper
• Reactive oxygen species, oxidative stress, and cardiovascular diseases

  2016cites this paper
• Role of oxidised protein repair for skeletal muscle homeostasis

  2016cites this paper
• Prognostic Importance of Serum Uric Acid in Acute Ischaemic Stroke

  2016cites this paper
• Review Article: Xanthine Oxidoreductase-An Important Functional Component of Differentiation, Apoptosis and Aggressiveness of Tumors

  2016cites this paper
• Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease

  2016cites this paper
• Chapter 44 – Principles of Liver Preservation

  2015cites this paper
• Oxidative stress, unfolded protein response, and apoptosis in developmental toxicity.

  2015cites this paper
• Nitrite reduction by molybdoenzymes: a new class of nitric oxide-forming nitrite reductases

  2015cites this paper
• Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

  2015cites this paper
• Effect of N-acetylcysteine and allopurinol combination to protect spinal cord ischemia/reperfusion injury induced by aortic cross-clamping in rat model

  2015cites this paper
• Reperfusion injury and reactive oxygen species: The evolution of a concept☆

  2015cites this paper
• The role of miRNAs in stroke

  2015cites this paper
• Allopurinol-mediated lignocellulose-derived microbial inhibitor tolerance by Clostridium beijerinckii during acetone–butanol–ethanol (ABE) fermentation

  2015influential citation
• Purification of xanthine oxidase from bovine milk by affinity chromatography with a novel gel

  2015cites this paper
• Nitrite, a novel method to decrease ischemia/reperfusion injury in the rat liver.

  2015cites this paper
• Proteomic responses to environmentally induced oxidative stress

  2015cites this paper
• The Gastrointestinal Circulation: Physiology and Pathophysiology.

  2015cites this paper
• Pathophysiology of circulating xanthine oxidoreductase: new emerging roles for a multi-tasking enzyme.

  2014cites this paper
• How biology handles nitrite.

  2014cites this paper
• Sepsis, mitochondrial failure and multiple organ dysfunction.

  2014cites this paper
• Methods to Reduce Liver Ischemia/Reperfusion Injury

  2014cites this paper
• [Advances in the study of aldehyde oxidases].

  2014cites this paper
• Beneficial effects of green tea catechin on massive hepatectomy model in rats

  2014cites this paper
• Participação de diferentes subtipos de macrófagos e a contribuição do ácido úrico solúvel, dos receptores TLR2 e TLR4 e das moléculas MyD88 e NLRP3 para o desenvolvimento da fibrose renal.

  2014cites this paper
• The Positive and Negative Aspects of Reactive Oxygen Species in Sports Performance

  2013cites this paper
• FARMAKOLOŠKE, TOKSIKOLOŠKE I BIOHEMIJSKE OSOBINE PREPARATA GLJIVE COPRINUS COMATUS

  2013cites this paper
• Effect of hydroxytyrosol supplementation on muscle damage in healthy human following an acute bout of exercise

  2013cites this paper
• Xanthine Oxidase Does Not Contribute to Apoptosis after Brain Hypoxia-Ischemia in Immature Rabbits

  2013cites this paper
• Expression and modification proteomics during skeletal muscle ageing

  2013cites this paper
• Allopurinol as a Preventive Contrivance after Acute Ischemic Stroke in Patients with a High Level of Serum Uric Acid: A Randomized, Controlled Trial

  2013cites this paper
• Effect of Procedural Pain on Purines, MDA and Allantoin in Premature Infants

  2013cites this paper
• The role of oxidative stress during inflammatory processes

  2013cites this paper
• [A pathophysiological role of cytochrome p450 involved in production of reactive oxygen species].

  2013cites this paper
• Oxidative status interactome map: towards novel approaches in experiment planning, data analysis, diagnostics and therapy.

  2013cites this paper
• Δ8‐Tetrahydrocannabivarin prevents hepatic ischaemia/reperfusion injury by decreasing oxidative stress and inflammatory responses through cannabinoid CB2 receptors

  2012cites this paper
• A new cannabinoid CB2 receptor agonist HU‐910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury

  2012cites this paper
• Lung Oxidative Damage by Hypoxia

  2012cites this paper
• Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia–reperfusion: Therapeutic potential of mitochondrially targeted antioxidants

  2012cites this paper
• Current strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen species.

  2012cites this paper
• Nitric Oxide and Inflammation

  2012cites this paper
• Aldehyde oxidase functions as a superoxide generating NADH oxidase: an important redox regulated pathway of cellular oxygen radical formation.

  2012influential citation
• The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion.

  2012cites this paper
• Noninvasive skin measurements to monitor chronic renal failure pathogenesis.

  2011cites this paper
• Hepatic ischemia–reperfusion injury and therapeutic strategies to alleviate cellular damage

  2011cites this paper
• Xanthine oxidoreductase: A journey from purine metabolism to cardiovascular excitation-contraction coupling

  2011cites this paper
• Cannabidiol protects against hepatic ischemia/reperfusion injury by attenuating inflammatory signaling and response, oxidative/nitrative stress, and cell death

  2011cites this paper
• Biochemical measurement of neonatal hypoxia.

  2011cites this paper
• Nitric oxide and redox regulation in the liver: part II. Redox biology in pathologic hepatocytes and implications for intervention.

  2011influential citation
• Allopurinol and xanthine oxidase inhibition in liver ischemia reperfusion

  2011cites this paper
• Skeletal Muscle Dysfunction in Patients with Chronic Obstructive Pulmonary Disease

  2010cites this paper
• Inchinkoto, an Herbal Medicine, Exerts Beneficial Effects in the Rat Liver Under Stress With Hepatic Ischemia-Reperfusion and Subsequent Hepatectomy

  2010cites this paper
• Soluble Receptors for Advanced Glycation End Products (sRAGE) as a Predictor of Restenosis Following Percutaneous Coronary Intervention

  2010cites this paper
• The Microcirculation and Oxidative Stress

  2010cites this paper
• Protein Carbonylation in Skeletal Muscles: Impact on Function

  2010cites this paper
• SUBMITTED TO HYPOXIA AND REOXYGENATION : action of the cytoprotectors prostaglandin E 1 , superoxide dismutase , allopurinol and verapamil

  2010cites this paper
• Cocaine induces oxidative damage to skin via xanthine oxidase and nitric oxide synthase.

  2010cites this paper
• Antioxidant Defense Mechanisms

  2010cites this paper
• Modern strategies to identify new molecular targets for the treatment of liver diseases: The promising role of Proteomics and Redox Proteomics investigations

  2009cites this paper
• Exposure of human keratinocytes to ischemia, hyperglycemia and their combination induces oxidative stress via the enzymes inducible nitric oxide synthase and xanthine oxidase.

  2009cites this paper
• Reactive oxygen species and peroxisomes: Struggling for balance

  2009cites this paper
• Study of rat hepatocytes in primary culture submitted to hypoxia and reoxygenation: action of the cytoprotectors prostaglandin E1, superoxide dismutase, allopurinol and verapamil.

  2009cites this paper
• Reactive oxygen species and N-methyl-D-aspartate receptor-mediated central sensitization in hindlimb ischemia/reperfusion injury-induced neuropathic pain rats.

  2009cites this paper
• Peroxisomes and reactive oxygen species, a lasting challenge

  2009cites this paper
• Production, detection, and adaptive responses to free radicals in exercise.

  2008cites this paper
• Effect of allopurinol on oxidant stress and hepatic function following ischemia and reperfusion in the rat.

  2008cites this paper
• Psychotropic Drug and Oxidative Stress in Acute Poisoning.

  2008cites this paper
• The Hepatoprotective Effect of Nitric Oxide Modulators and Antioxidants in Hepatic Ischemia/Reperfusion Injury in Albino Rats

  2008cites this paper
• The potential value of natural antioxidative treatment in glaucoma.

  2008cites this paper
• Biochemical markers of neonatal hypoxia

  2008cites this paper
• Antioxidants

  2008cites this paper
• Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats.

  2008cites this paper
• Oxidative inactivation of key mitochondrial proteins leads to dysfunction and injury in hepatic ischemia reperfusion.

  2008cites this paper
• Skeletal muscle dysfunction in patients with chronic obstructive pulmonary disease

  2008cites this paper