Structure and activity of putative intronic miRNA promoters.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  RNA: A publication of the RNA Society

• Publication date

  2010-03-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1261/rna.1731910PMID 20075166PMCID PMC2822915
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines.

  2009cited by this paper
• High-resolution human core-promoter prediction with CoreBoost_HM.

  2009influential reference
• The Promoter of the pri-miR-375 Gene Directs Expression Selectively to the Endocrine Pancreas

  2009cited by this paper
• MicroRNA-21 Is Up-Regulated in Allergic Airway Inflammation and Regulates IL-12p35 Expression 1

  2009cited by this paper
• MicroRNA-101, down-regulated in hepatocellular carcinoma, promotes apoptosis and suppresses tumorigenicity.

  2009cited by this paper
• Chromatin structure analyses identify miRNA promoters

  2008influential reference
• Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs.

  2008cited by this paper
• SeqMap: mapping massive amount of oligonucleotides to the genome

  2008cited by this paper
• A single Hox locus in Drosophila produces functional microRNAs from opposite DNA strands.

  2008cited by this paper
• Annotation of mammalian primary microRNAs

  2008cited by this paper
• MicroRNA-17-92 down-regulates expression of distinct targets in different B-cell lymphoma subtypes.

  2008cited by this paper
• Primary microRNA transcripts are processed co-transcriptionally

  2008cited by this paper
• Putative promoter regions of miRNA genes involved in evolutionarily conserved regulatory systems among vertebrates

  2008cited by this paper
• Primary microRNA transcript retention at sites of transcription leads to enhanced microRNA production

  2008cited by this paper
• Chromatin structure analyses identify miRNA promoters.

  2008cited by this paper
• Characterization and Identification of MicroRNA Core Promoters in Four Model Species

  2007cited by this paper
• Intronic microRNA precursors that bypass Drosha processing

  2007cited by this paper
• MicroRNA targeting specificity in mammals: determinants beyond seed pairing.

  2007cited by this paper
• Processing of intronic microRNAs

  2007cited by this paper
• The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila.

  2007cited by this paper
• miRBase: tools for microRNA genomics

  2007cited by this paper
• BMC Genomics BioMed Central

  2007cited by this paper
• MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia

  2007influential reference
• Mammalian mirtron genes.

  2007cited by this paper
• Genomic analysis of human microRNA transcripts

  2007cited by this paper
• Annotating noncoding RNA genes.

  2007influential reference
• CpG Island Hypermethylation of Tumor Suppressor microRNAs in Human Cancer

  2007cited by this paper
• Characterization of microRNA expression profiles in normal human tissues

  2007cited by this paper
• Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

  2006cited by this paper
• RNA polymerase III transcribes human microRNAs

  2006influential reference
• Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation.

  2005cited by this paper
• Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets.

  2005cited by this paper
• Rna Polymerase III

  2005cited by this paper
• Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes.

  2005cited by this paper
• Human RISC couples microRNA biogenesis and posttranscriptional gene silencing.

  2005cited by this paper
• Distinct Mechanisms for Repression of RNA Polymerase III Transcription by the Retinoblastoma Tumor Suppressor Protein

  2004influential reference
• Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs.

  2004cited by this paper
• HIP1: trafficking roles and regulation of tumorigenesis.

  2004cited by this paper
• Nuclear Export of MicroRNA Precursors

  2004cited by this paper
• p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB

  2003cited by this paper
• Concerted Changes in the Nucleotide Sequences of the Intragenic Promoter Regions of Eukaryotic Genes for tRNAs of All Specificities

  2003cited by this paper
• The nuclear RNase III Drosha initiates microRNA processing

  2003cited by this paper
• Saturation mutagenesis.

  2003cited by this paper
• TP53 is frequently altered by methylation, mutation, and/or deletion in acute lymphoblastic leukaemia

  2003influential reference
• Micro RNAs are complementary to 3′ UTR sequence motifs that mediate negative post-transcriptional regulation

  2002cited by this paper
• MicroRNA maturation: stepwise processing and subcellular localization

  2002cited by this paper
• Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

  2002cited by this paper
• Computational detection and location of transcription start sites in mammalian genomic DNA.

  2002cited by this paper
• Role for a bidentate ribonuclease in the initiation step of RNA interference

  2001cited by this paper
• A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA

  2001cited by this paper
• Variation in the reversibility of evolution

  2000cited by this paper
• Termination sequence requirements vary among genes transcribed by RNA polymerase III.

  1999cited by this paper
• Expression of the Striatal DARPP-32/ARPP-21 Phenotype in GABAergic Neurons Requires Neurotrophins In Vivo andIn Vitro

  1999cited by this paper
• p53 is a general repressor of RNA polymerase III transcription

  1998cited by this paper
• Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.

  1996cited by this paper
• Both RNA polymerase III and RNA polymerase II accurately initiate transcription from a human U6 promoter in vitro.

  1995cited by this paper
• RNA polymerase III. Genes, factors and transcriptional specificity.

  1993cited by this paper
• CpG islands as gene markers in the human genome.

  1992cited by this paper
• Expression of RNase P RNA in Saccharomyces cerevisiae is controlled by an unusual RNA polymerase III promoter.

  1991cited by this paper
• Saturation mutagenesis of the Drosophila tRNA(Arg) gene B-Box intragenic promoter element: requirements for transcription activation and stable complex formation.

  1990cited by this paper
• Transcription by RNA polymerase III.

  1988cited by this paper
• Point mutations in the 5' ICR and anticodon region of a Drosophila tRNAArg gene decrease in vitro transcription.

  1985cited by this paper
• Transcription by RNA polymerase III.

  1983cited by this paper
• Nucleotide sequences in Xenopus 5S DNA required for transcription termination.

  1981cited by this paper

• Dynamic miRNA–host gene co-expression and functional regulation in response to salinity fluctuations during biological invasions

  2026cites this paper
• MicroRNA profiling identifies VHL/HIF-2α dependent miR-2355-5p as a key modulator of clear cell Renal cell carcinoma tumor growth

  2025cites this paper
• Partners in Silencing: Decoding the Mammalian Argonaute Interactome

  2025cites this paper
• miR-6850 drives phenotypic changes and signaling in high grade serous ovarian cancer

  2025cites this paper
• Exploring the role of exosomal and non-exosomal non-coding RNAs in Kawasaki disease: Implications for diagnosis and therapeutic strategies against coronary artery aneurysms

  2025cites this paper
• Biological Roles of Selected microRNAs in Glucose Metabolism as a Candidate Biomarker for Diabetes Mellitus

  2025cites this paper
• CRISPR-Activation: Boosting Expression of Plant MIRs.

  2025cites this paper
• Hsa-miR-21-5p is induced by interleukin-6 and affects multiple pathogenic factors associated with fibroblast-like synoviocytes in rheumatoid arthritis

  2025cites this paper
• Current Trends in Gene Therapy to Treat Inherited Disorders of the Brain.

  2025cites this paper
• Evaluating Genetic Regulators of MicroRNAs Using Machine Learning Models

  2025cites this paper
• Methylation of microRNA genes and its effect on secondary xylem development of stem in poplar

  2024cites this paper
• Next-Cell Hypothesis: Mechanism of Obesity-Associated Carcinogenesis.

  2024cites this paper
• Ribosomal protein L24 mediates mammalian microRNA processing in an evolutionarily conserved manner

  2024cites this paper
• A microRNA is the effector gene of a classic evolutionary hotspot locus.

  2024cites this paper
• Intronic miR-6741-3p targets the oncogene SRSF3: Implications for oral squamous cell carcinoma pathogenesis

  2024cites this paper
• miR-198 targets TOPORS: implications for oral squamous cell carcinoma pathogenesis

  2024cites this paper
• Expression and Functional Analysis of Immuno-Micro-RNAs mir-146a and mir-326 in Colorectal Cancer

  2024cites this paper
• MiR-128-3p – a gray eminence of the human central nervous system

  2024cites this paper
• A micro-RNA is the effector gene of a classic evolutionary hotspot locus

  2024cites this paper
• MicroRNAs as Epigenetic Regulators of Obesity.

  2024cites this paper
• The roles of miRNAs in adult skeletal muscle satellite cells.

  2023cites this paper
• Modulation of the Cellular microRNA Landscape: Contribution to the Protective Effects of High-Density Lipoproteins (HDL)

  2023cites this paper
• Functional mapping of microRNA promoters with dCas9 fused to transcriptional regulators

  2023cites this paper
• Ribosomal protein L24 modulates mammalian microRNA processing and transfer RNA fragment production

  2023cites this paper
• A Data-Mining Approach to Identify NF-kB-Responsive microRNAs in Tissues Involved in Inflammatory Processes: Potential Relevance in Age-Related Diseases

  2023cites this paper
• MicroRNA‐128 suppresses tau phosphorylation and reduces amyloid‐beta accumulation by inhibiting the expression of GSK3β, APPBP2, and mTOR in Alzheimer's disease

  2023cites this paper
• Coregulatory mechanism and interactome network of miRNA, lncRNA, and mRNA involved in Human Diseases

  2023cites this paper
• Overview of the role and action mechanism of microRNA-128 in viral infections.

  2023cites this paper
• miRNA Biogenesis and Regulation of Diseases: An Updated Overview.

  2023cites this paper
• Insights into Online microRNA Bioinformatics Tools

  2023cites this paper
• Mitochondrial miRNA as Epigenomic Signatures: Visualizing Aging-Associated Heart Diseases Through a New Lens.

  2023cites this paper
• miR-126 identifies a quiescent and chemo-resistant human B-ALL cell subset that correlates with minimal residual disease

  2023cites this paper
• Gene regulation in animal miRNA biogenesis.

  2022cites this paper
• miR-140-5p and miR-140-3p: Key Actors in Aging-Related Diseases?

  2022cites this paper
• Regulatory RNAs in the Molecular Pathology of Neoplasia

  2022cites this paper
• MicroRNAs and Synaptic Plasticity: From Their Molecular Roles to Response to Therapy

  2022cites this paper
• MicroRNAs in kidney development and disease

  2022cites this paper
• The Extensive Regulation of MicroRNA in Immune Thrombocytopenia

  2022cites this paper
• MicroRNAs in the development of potential therapeutic targets against COVID-19: A narrative review

  2022cites this paper
• MicroRNAs: master regulators in host–parasitic protist interactions

  2022cites this paper
• Role of MicroRNA-7 (MiR-7) in Cancer Physiopathology

  2022cites this paper
• Low miR-92a-3p in oocytes mediates the multigenerational and transgenerational inheritance of poor cartilage quality in rat induced by prenatal dexamethasone exposure.

  2022cites this paper
• The microRNA Lifecycle in Health and Cancer

  2022cites this paper
• Molecular Approaches and Echocardiographic Deformation Imaging in Detecting Myocardial Fibrosis

  2022cites this paper
• Broad genomic workup including optical genome mapping uncovers a DDX3X: MLLT10 gene fusion in acute myeloid leukemia

  2022cites this paper
• miRNA-Dependent CD4+ T Cell Differentiation in the Pathogenesis of Multiple Sclerosis

  2021cites this paper
• Roles of microRNAs in renal disorders related to primary podocyte dysfunction.

  2021cites this paper
• MicroRNA Sequences Modulated by Beta Cell Lipid Metabolism: Implications for Type 2 Diabetes Mellitus

  2021cites this paper
• Splice and Dice: Intronic microRNAs, Splicing and Cancer

  2021influential citation
• Slow transcription of the 99a/let-7c/125b-2 cluster results in differential miRNA expression and promotes melanoma phenotypic plasticity.

  2021cites this paper
• miR-208b Reduces the Expression of Kcnj5 in a Cardiomyocyte Cell Line

  2021cites this paper
• A reciprocal feedback of miR-548ac/YB-1/Snail induces EndMT of HUVECs during acidity microenvironment

  2021cites this paper
• Systematic Analysis of Intronic miRNAs Reveals Cooperativity within the Multicomponent FTX Locus to Promote Colon Cancer Development

  2020cites this paper
• Does microRNA Perturbation Control the Mechanisms Linking Obesity and Diabetes? Implications for Cardiovascular Risk

  2020cites this paper
• LncRNA MALAT1 Promotes STAT3-Mediated Endothelial Inflammation by Counteracting the Function of miR-590

  2020cites this paper
• Age-related alterations on ultrastructure and gene expression profile of the female Blood-Brain Barrier

  2020cites this paper
• Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33

  2020cites this paper
• Epigenetic Regulators Involved in Osteoclast Differentiation

  2020cites this paper
• MicroRNA sequences modulating inflammation and lipid accumulation in macrophage “foam” cells: Implications for atherosclerosis

  2020cites this paper
• Computational prediction of miRNA/mRNA duplexomes at the whole human genome scale reveals functional subnetworks of interacting genes with embedded miRNA annealing motifs

  2020cites this paper
• Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088)

  2020cites this paper
• TAL1 und miR-17-92 bilden eine regulatorische Schleife in der Hämatopoese

  2020cites this paper
• miRNA Clusters with Down-Regulated Expression in Human Colorectal Cancer and Their Regulation

  2020cites this paper
• Antagonism between splicing and microprocessor complex dictates the serum-induced processing of lnc-MIRHG for efficient cell cycle reentry

  2020cites this paper
• Identification of differentially methylated miRNA genes during compatible and incompatible interactions between soybean and soybean cyst nematode.

  2020cites this paper
• Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth

  2020cites this paper
• miR-378 and its host gene Ppargc1β exhibit independent expression in mouse skeletal muscle.

  2020cites this paper
• The impact of microRNAs on alterations of gene regulatory networks in allergic diseases.

  2020cites this paper
• The Fundamentals of miRNA Biology: Structure, Biogenesis, and Regulatory Functions

  2020cites this paper
• Feedback motifs tuned by microRNAs in human transcriptional networks

  2020cites this paper
• Dynamical gene regulatory networks are tuned by transcriptional autoregulation with microRNA feedback

  2020cites this paper
• MicroRNAs-Based Nano-Strategies as New Therapeutic Approach in Multiple Myeloma to Overcome Disease Progression and Drug Resistance

  2020cites this paper
• MicroRNAs: pivotal regulators in acute myeloid leukemia

  2020cites this paper
• Hypoxia-Induced miR-675-5p Supports β-Catenin Nuclear Localization by Regulating GSK3-β Activity in Colorectal Cancer Cell Lines

  2020cites this paper
• L’épigénétique et la construction du phénotype chez le bovin

  2020cites this paper
• miR-15/107 microRNA Gene Group: Characteristics and Functional Implications in Cancer

  2020cites this paper
• Consequences of assisted reproductive techniques on the embryonic epigenome in cattle.

  2019cites this paper
• Characterization of novel primary miRNA transcription units in human cells using Bru-seq nascent RNA sequencing

  2019cites this paper
• Novel miR-29b target regulation patterns are revealed in two different cell lines

  2019cites this paper
• The Regulatory Role of MicroRNAs in Breast Cancer

  2019cites this paper
• The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer

  2019cites this paper
• miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7

  2019cites this paper
• Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart

  2019cites this paper
• Computational identification and analysis of early diagnostic biomarkers for kidney cancer

  2019cites this paper
• Clustered microRNAs hsa-miR-221-3p/hsa-miR-222-3p and their targeted genes might be prognostic predictors for hepatocellular carcinoma

  2019cites this paper
• Modulation and Evolution of Animal Development through microRNA Regulation of Gene Expression

  2019cites this paper
• Expression and functional properties of selected miRNAs in human cancer tissue and cancer cell lines

  2019cites this paper
• Estrogen receptor-α regulation of microRNA-590 targets FAM171A1—a modifier of breast cancer invasiveness

  2019cites this paper
• Rôle et potentiel thérapeutique des microARNs dans le diabète

  2019cites this paper
• Pan-cancer analysis on microRNA-associated gene activation

  2019cites this paper
• Role of MiR-148b in angiogenesis and endothelial cell plasticity

  2019cites this paper
• Epigenetic regulation of genes related to lipid metabolism by microrna in mice fed high fat diet

  2018cites this paper
• Epigenetic Mechanisms in Osteoporosis

  2018cites this paper
• Assessing the functional association of intronic miRNAs with their host genes

  2018influential citation
• Novel insights into the regulation of miRNA transcriptional control: implications for T2D and related complications

  2018cites this paper
• Gene regulation in psoriatic keratinocytes: microRNAs and cytokine responses

  2018cites this paper
• miR-126-5p by direct targeting of JNK-interacting protein-2 (JIP-2) plays a key role in Theileria-infected macrophage virulence

  2018cites this paper
• ALUminating the Path of Atherosclerosis Progression: Chaos Theory Suggests a Role for Alu Repeats in the Development of Atherosclerotic Vascular Disease

  2018cites this paper
• Global DNA Methylation Changes in Soybean as a response to Soybean Cyst Nematode (SCN) infection.

  2018cites this paper
• MicroRNAs, Regulatory Messengers Inside and Outside Cancer Cells.

  2018cites this paper