Mouse models for radiation-induced cancers.

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Mutagenesis

• Publication date

  2016-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/mutage/gew019PMID 27209205PMCID PMC6280996
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chronic lymphocytic leukaemia.

  2018influential reference
• Are Exposures to Multiple Frequencies the Key to Future Radiofrequency Research?

  2017cited by this paper
• Radiation-induced myeloid leukemia in murine models

  2014cited by this paper
• Chernobyl fallout and cancer incidence in Finland 1988–2007

  2014cited by this paper
• Phthalates and Childhood Asthma: Revealing an Association through Urinary Biomarkers

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• Emerging molecular networks in Burkitt's lymphoma

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• Cancer risk in 680 000 people exposed to computed tomography scans in childhood or adolescence: data linkage study of 11 million Australians

  2013cited by this paper
• Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study

  2012cited by this paper
• Prognostic and Predictive Value of K-RAS Mutations in Non-Small Cell Lung Cancer

  2012cited by this paper
• Reproductive status at first diagnosis influences risk of radiation-induced second primary contralateral breast cancer in the WECARE study.

  2012cited by this paper
• SEER Cancer Statistics Review, 1975–2009 (Vintage 2009 Populations)

  2012cited by this paper
• The significance of PTEN and AKT aberrations in pediatric T-cell acute lymphoblastic leukemia

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• MicroRNAs in B cell development and malignancy

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• Effect of antioxidants on X-ray-induced γ-H2AX foci in human blood lymphocytes: preliminary observations.

  2012cited by this paper
• EPHA7, a new target gene for 6q deletion in T-cell lymphoblastic lymphomas.

  2012cited by this paper
• Normal tissue protection for improving radiotherapy: Where are the Gaps?

  2012cited by this paper
• Flt3-ITD mutations in a mouse model of radiation-induced acute myeloid leukaemia

  2012cited by this paper
• Radiation and Smoking Effects on Lung Cancer Incidence by Histological Types Among Atomic Bomb Survivors

  2012cited by this paper
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  2012cited by this paper
• Induction of ZEB Proteins by Inactivation of RB Protein Is Key Determinant of Mesenchymal Phenotype of Breast Cancer*

  2012cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Ikaros and tumor suppression in acute lymphoblastic leukemia.

  2011cited by this paper
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  2011influential reference
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  2011cited by this paper
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  2011influential reference
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• Risks associated with low doses and low dose rates of ionizing radiation: why linearity may be (almost) the best we can do.

  2009cited by this paper
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  2009cited by this paper
• The proportion of childhood leukaemia incidence in Great Britain that may be caused by natural background ionizing radiation

  2009cited by this paper
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  2009cited by this paper
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• Dose to the contralateral breast from radiotherapy and risk of second primary breast cancer in the WECARE study.

  2008cited by this paper
• LENT Late effects of cancer treatment on normal tissues

  2008cited by this paper
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  2008cited by this paper
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• Mtf-1 lymphoma-susceptibility locus affects retention of large thymocytes with high ROS levels in mice after gamma-irradiation.

  2007cited by this paper
• Cancer Epidemiology and Prevention, 3rd Edition

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• Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias.

  2006cited by this paper
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• Radiation carcinogenesis in mouse thymic lymphomas

  2006cited by this paper
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  2006cited by this paper
• Cancer epidemiology and prevention.

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• Evidence for complex multigenic inheritance of radiation AML susceptibility in mice revealed using a surrogate phenotypic assay.

  2006cited by this paper
• Dose-guided radiation therapy with megavoltage cone-beam CT.

  2006cited by this paper
• DNA methylation during mouse hemopoietic differentiation and radiation-induced leukemia.

  2006cited by this paper
• The origins and uses of mouse outbred stocks

  2005influential reference
• Ionizing radiation and breast cancer in men (United States)

  2005cited by this paper
• Mutations of the PU.1 Ets domain are specifically associated with murine radiation-induced, but not human therapy-related, acute myeloid leukaemia

  2005influential reference
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• How tissues respond to damage at the cellular level: orchestration by transforming growth factor-β (TGF-β)

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• Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1)

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• Integrative radiation carcinogenesis: interactions between cell and tissue responses to DNA damage.

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