Nitric oxide mediates cytotoxicity and basic fibroblast growth factor release in cultured vascular smooth muscle cells. A possible mechanism of neovascularization in atherosclerotic plaques.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Journal of Clinical Investigation

• Publication date

  1995-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI117712PMID 7532188PMCID PMC295533
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Nitric Oxide: Physiology and Pharmacology

  1995cited by this paper
• Distinct patterns of expression of fibroblast growth factors and their receptors in human atheroma and nonatherosclerotic arteries. Association of acidic FGF with plaque microvessels and macrophages.

  1993cited by this paper
• Nitric oxide promotes DNA synthesis and cyclic GMP formation in endothelial cells from postcapillary venules.

  1993cited by this paper
• Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease.

  1993cited by this paper
• Nitric oxide mediates interleukin-1-induced cellular cytotoxicity in the rat ovary. A potential role for nitric oxide in the ovulatory process.

  1993cited by this paper
• Nitric oxide mediates interleukin-1-induced prostaglandin E2 production by vascular smooth muscle cells.

  1993cited by this paper
• Cloning of inducible nitric oxide synthase in rat vascular smooth muscle cells.

  1993cited by this paper
• Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: comparison with enzymatically formed nitric oxide from L-arginine.

  1993cited by this paper
• Prostaglandin-induced apoptosis of ovarian surface epithelial cells.

  1993cited by this paper
• Nitric oxide synthase induces macrophage death by apoptosis.

  1993cited by this paper
• Elimination of smooth muscle cells in experimental restenosis: targeting of fibroblast growth factor receptors.

  1992cited by this paper
• Nitric oxide: first in a new class of neurotransmitters.

  1992cited by this paper
• Biochemistry of nitric oxide and its redox-activated forms.

  1992cited by this paper
• Molecular and biological properties of the vascular endothelial growth factor family of proteins.

  1992cited by this paper
• Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries.

  1992cited by this paper
• [Quantification of mRNA using the polymerase chain reaction--cytokines in rheumatoid arthritis].

  1992cited by this paper
• Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro.

  1992cited by this paper
• Nitric oxide: a pathogenetic factor in autoimmunity.

  1992cited by this paper
• Balloon injury and interleukin-1 beta induce nitric oxide synthase activity in rat carotid arteries.

  1992cited by this paper
• Inhibition of smooth muscle cell proliferation in injured rat arteries. Interaction of heparin with basic fibroblast growth factor.

  1992cited by this paper
• Aortic smooth muscle cells express and secrete vascular endothelial growth factor.

  1991cited by this paper
• Suppression of solid tumor growth by immunoneutralizing monoclonal antibody against human basic fibroblast growth factor.

  1991cited by this paper
• Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells.

  1991cited by this paper
• Release of nitric oxide from human vascular smooth muscle cells.

  1991cited by this paper
• Synthesis of IL-1 alpha and IL-1 beta by arterial cells in atherosclerosis.

  1991cited by this paper
• Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

  1991cited by this paper
• Antimitogenic and mitogenic actions of interleukin-1 in diverse cell types are associated with induction of gro gene expression.

  1991cited by this paper
• Nitric oxide: physiology, pathophysiology, and pharmacology.

  1991cited by this paper
• Angiogenesis in arteries: review.

  1991cited by this paper
• Role of protein kinase C in the inhibition by fibroblast growth factor of apoptosis in serum-depleted endothelial cells.

  1990cited by this paper
• Cell proliferation in human coronary arteries.

  1990cited by this paper
• Quantitation of mRNA by the polymerase chain reaction.

  1989cited by this paper
• Regulation of macrophage functions by L-arginine

  1989cited by this paper
• Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA.

  1989cited by this paper
• Monoclonal Antibodies Against Human Basic Fibroblast Growth Factor

  1989cited by this paper
• Injury‐induced release of basic fibroblast growth factor from bovine aortic endothelium

  1989cited by this paper
• Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis.

  1989cited by this paper
• Production of platelet-derived growth factor-like mitogen by smooth-muscle cells from human atheroma.

  1988cited by this paper
• Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids.

  1988cited by this paper
• Differentiation of murine macrophages to express nonspecific cytotoxicity for tumor cells results in L-arginine-dependent inhibition of mitochondrial iron-sulfur enzymes in the macrophage effector cells.

  1988cited by this paper
• Capillary endothelial cells express basic fibroblast growth factor, a mitogen that promotes their own growth

  1987cited by this paper
• Human vascular smooth muscle cells both express and respond to heparin-binding growth factor I (endothelial cell growth factor).

  1987cited by this paper
• Angiogenic factors.

  1987cited by this paper
• Effects of prostaglandins on the cytosolic free calcium concentration in vascular smooth muscle cells.

  1986cited by this paper
• The pathogenesis of atherosclerosis--an update.

  1986cited by this paper
• Ultrastructure of the human aortic fibrolipid lesion. Formation of the atherosclerotic lipid-rich core.

  1986cited by this paper
• Immunoreactive fibroblast growth factor in cells of peritoneal exudate suggests its identity with macrophage-derived growth factor.

  1985cited by this paper
• Corpus luteum angiogenic factor is related to fibroblast growth factor.

  1985cited by this paper
• Human atherosclerosis. I. Cell constitution and characteristics of advanced lesions of the superficial femoral artery.

  1984cited by this paper
• Hypothesis: vasa vasorum and neovascularization of human coronary arteries. A possible role in the pathophysiology of atherosclerosis.

  1984cited by this paper
• Prostaglandin E1 inhibits DNA synthesis in arterial smooth muscle cells stimulated with platelet-derived growth factor.

  1984cited by this paper
• Studies of Hypercholesterolemia in the Nonhuman Primate: I. Changes that Lead to Fatty Streak Formation

  1984cited by this paper
• The Importance of Hemorrhage in the Relationship Between Gross Morphologic Characteristics and Cerebral Symptoms in 376 Carotid Artery Plaques

  1983cited by this paper
• Carotid artery stenosis following endarterectomy.

  1982cited by this paper
• Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria.

  1973cited by this paper

• Recent advances in targeted therapy for inflammatory vascular diseases.

  2024cites this paper
• Nitric Oxide Delivering Surfaces: An Overview of Functionalization Strategies and Efficiency Progress

  2022cites this paper
• Phenotypic Modulation of Macrophages and Vascular Smooth Muscle Cells in Atherosclerosis—Nitro-Redox Interconnections

  2021cites this paper
• Role of fish collagen hydrolysate in attenuating inflammation-An in vitro study.

  2021cites this paper
• Effects of deoxynivalenol (DON) and its microbial biotransformation product deepoxy-deoxynivalenol (DOM-1) on a trout, pig, mouse, and human cell line

  2017cites this paper
• Oxide; NOS: Nitric Oxide Synthase; iNOS: Inducible Nitric Oxide Synthase; ecNOS: Endothelial Nitric Oxide Synthase and nNOS: Neuronal Nitric Oxide Synthase

  2017cites this paper
• Histological and immunohistochemical effects of L-arginine and silymarin on TNBS-induced inflammatory bowel disease in rats.

  2016cites this paper
• Gelatin-siloxane nanoparticles to deliver nitric oxide for vascular cell regulation: synthesis, cytocompatibility, and cellular responses.

  2015cites this paper
• Cell injury-induced release of FGF2: relevance to intracerebral mesenchymal stromal cell transplantations.

  2015cites this paper
• Nitric oxide deficiency in pulmonary hypertension: Pathobiology and implications for therapy

  2013cites this paper
• Signaling regulation of fetoplacental angiogenesis.

  2012cites this paper
• Regulation of Cell Physiology and Pathology by Protein S-Glutathionylation: Lessons Learned from the Cardiovascular System

  2012cites this paper
• Role of endothelial cell stress in the pathogenesis of chronic heart failure.

  2009cites this paper
• Immunomodulatory effects of specific bacterial components of Lactobacillus plantarum KFCC11389P on the murine macrophage cell line RAW 264·7

  2009cites this paper
• Pharmacogenetics of the neurodevelopmental impact of anticancer chemotherapy.

  2008cites this paper
• Vascular injury and modulation of MAPKs: a targeted approach to therapy of restenosis.

  2007cites this paper
• The nitric oxide/cGMP signaling pathway in pulmonary hypertension.

  2007cites this paper
• Glucosamine HCl alters production of inflammatory mediators by rat intervertebral disc cells in vitro.

  2007cites this paper
• Stem Cell Factor Attenuates Vascular Smooth Muscle Apoptosis and Increases Intimal Hyperplasia After Vascular Injury

  2007cites this paper
• Papel del endotelio en la hipertensión

  2007cites this paper
• Study on the Correlations among Disease Activity Index and Salivary Transforming Growth Factor‐β1 and Nitric Oxide in Ulcerative Colitis Patients

  2007cites this paper
• Exogenous Nitric Oxide Stimulates Cell Proliferation via Activation of a Mitogen-Activated Protein Kinase Pathway in Ovine Fetoplacental Artery Endothelial Cells1

  2006cites this paper
• Modulatory Activity of Bifidobacterium sp. BGN4 Cell Fractions on Immune Cells

  2006cites this paper
• Endothelial Dysfunction and Atherosclerosis: Role of Dietary Fats

  2006cites this paper
• Angiotensin II regulation of ovine fetoplacental artery endothelial functions: interactions with nitric oxide

  2005cites this paper
• Nitric oxide in inflammatory bowel disease: a universal messenger in an unsolved puzzle

  2004cites this paper
• Angiotensin AT1 receptor upregulates expression of basic fibroblast growth factor, basic fibroblast growth factor receptor and coreceptor in human coronary smooth muscle cells

  2004cites this paper
• Fas ligand gene therapy for vascular intimal hyperplasia.

  2004cites this paper
• Moderate regular exercise increases basal production of nitric oxide in elderly women.

  2004cites this paper
• Regulation of VEGF and bFGF mRNA expression and other proliferative compounds in skeletal muscle cells

  2004cites this paper
• Pathological angiogenesis is reduced by targeting pericytes via the NG2 proteoglycan

  2004cites this paper
• [Prerequisites for development of endothelial dysfunction in rheumatoid arthritis].

  2004cites this paper
• Nitric oxide in vascular biology

  2003cites this paper
• Upregulation of cAMP is a new functional signal pathway of Klotho in endothelial cells.

  2003cites this paper
• Basic fibrobrast growth factor induces the secretion of vascular endothelial growth factor by human aortic smooth muscle cells but not by endothelial cells

  2003cites this paper
• Inhibitory effects of ursodeoxycholic acid on the induction of nitric oxide synthase in vascular smooth muscle cells.

  2003cites this paper
• Contribution of nitric oxide-mediated apoptosis to cancer metastasis inefficiency.

  2003cites this paper
• Nitric Oxide in Inflammatory Bowel Disease

  2003cites this paper
• Cytokine Regulation of Nitric Oxide Production

  2002cites this paper
• Angiogenic markers, neovascularization and malignant deformation of Barrett's esophagus.

  2002cites this paper
• Effects of lipopolysaccharide on low- and high-density cultured rabbit vascular smooth muscle cells: differential modulation of nitric oxide release, ERK1/ERK2 MAP kinase activity, protein tyrosine phosphatase activity, and DNA synthesis.

  2002influential citation
• Arachidonic acid release by cPLA2 may be causally related to NO‐induced apoptosis in vascular smooth muscle cells

  2002cites this paper
• Fas ligand/Fas-mediated apoptosis in human coronary artery smooth muscle cells: therapeutic implications of fratricidal mode of action.

  2001cites this paper
• Vasoresponsiveness of sarcoidosis-associated pulmonary hypertension.

  2001cites this paper
• The role of nitric oxide in the formation of keloid and hypertrophic lesions.

  2001cites this paper
• Altered arterial expression patterns of inducible and endothelial nitric oxide synthase in pulmonary plexogenic arteriopathy caused by congenital heart disease.

  2001cites this paper
• Acute and Chronic Smooth Muscle Cell Apoptosis After Mechanical Vascular Injury Can Occur Independently of the Fas-Death Pathway

  2001cites this paper
• High levels of exhaled nitric oxide (NO) and NO synthase III expression in lesional smooth muscle in lymphangioleiomyomatosis.

  2001cites this paper
• Tumor necrosis factor-a induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes

  2000cites this paper
• Mathematical modelling of nitric oxide activity in wound healing can explain keloid and hypertrophic scarring.

  2000cites this paper
• Bacille Calmette–Guérin (BCG)‐associated inflammation and fibrosis: modulation by recombinant BCG expressing interferon‐gamma (IFN‐γ)

  2000cites this paper
• Pulmonary arterial smooth muscle cells modulate cytokine- and LPS-induced cytotoxicity in endothelial cells.

  2000cites this paper
• Fluid flow releases fibroblast growth factor-2 from human aortic smooth muscle cells.

  2000cites this paper
• Endothelial dysfunction and coronary artery disease.

  2000cites this paper
• Expression of endothelial and inducible nitric oxide synthases and nitric oxide production in ovine placental and uterine tissues during late pregnancy.

  2000cites this paper
• Pulmonary vascular remodeling distal to pulmonary artery ligation is accompanied by upregulation of endothelin receptors and nitric oxide synthase.

  2000cites this paper
• Vasoactive substances in renal transplantation.

  2000cites this paper
• Tumor necrosis factor-alpha induces apoptosis via inducible nitric oxide synthase in neonatal mouse cardiomyocytes.

  2000cites this paper
• Nitric oxide and atherosclerosis

  2000cites this paper
• Expression of inducible nitric oxide synthase and Fas/Fas ligand correlates with the incidence of apoptotic cell death in atheromatous plaques of human coronary arteries.

  2000cites this paper
• Cytotoxicity, Apoptosis, and Nitric Oxide

  2000cites this paper
• Pranidipine enhances the action of nitric oxide released from endothelial cells.

  2000cites this paper
• Nitric oxide synthase expression, enzyme activity and NO production during angiogenesis in the chick chorioallantoic membrane

  2000cites this paper
• Cellular Signal Transduction and Nitric Oxide

  2000cites this paper
• Nitric Oxide in Atherosclerosis

  2000cites this paper
• Potentiation of hydrogen peroxide, nitric oxide, and cytokine production in RAW 264.7 macrophage cells exposed to human and commercial isolates of Bifidobacterium.

  1999cites this paper
• Nitric oxide donor induces upregulation of stress proteins in cold ischemic rat hearts.

  1999cites this paper
• A regulatory role of fibroblast growth factor in the expression of decorin, biglycan, betaglycan and syndecan in osteoblasts from patients with Crouzon's syndrome.

  1999cites this paper
• The significance of platelet-derived growth factors for proliferation of vascular smooth muscle cells.

  1999cites this paper
• Basic Fibroblast Growth Factor Increases Regional Myocardial Blood Flow and Salvages Myocardium in the Infarct Border Zone in a Rabbit Model of Acute Myocardial Infarction

  1999cites this paper
• Fluid flow releases fibroblast growth factor-2 from human aortic smooth muscle cells

  1999cites this paper
• Exhaled nitric oxide is increased in active fibrosing alveolitis.

  1999cites this paper
• Vascular Smooth Muscle Cell Biology and Restenosis

  1999cites this paper
• Nitric oxide inhibits wounds collagen synthesis.

  1999cites this paper
• Increase in prostaglandin E(2) production by interleukin-1beta in arterial smooth muscle cells derived from patients with moyamoya disease.

  1999cites this paper
• Increase in Prostaglandin E 2 Production by Interleukin-1 (cid:98) in Arterial Smooth Muscle Cells Derived From Patients With Moyamoya Disease Cellular Biology

  1999cites this paper
• The contribution of inducible nitric oxide and cytomegalovirus to the stability of complex carotid plaque.

  1999cites this paper
• The effect of coculture with human smooth muscle cells on the proliferation, the IL‐1 β secretion, the PDGF production and tube formation of human aortic endothelial cells

  1999cites this paper
• Nitric oxide inhibits wound collagen synthesis

  1999cites this paper
• Hypoxia stimulates proliferation and interleukin-1alpha production in human vascular smooth muscle cells.

  1999cites this paper
• Role of Nitric Oxide in Regulating Neonatal Porcine Pulmonary Artery Smooth Muscle Cell Proliferation

  1999cites this paper
• Endothelial expression of endothelial nitric oxide synthase and endothelin-1 in human coronary artery disease. Specific reference to underlying lesion.

  1999cites this paper
• Constitutive expression of interleukin-1α precursor promotes human vascular smooth muscle cell proliferation.

  1999cites this paper
• Kiyotaka Cells Derived From Patients With Moyamoya Disease in Arterial Smooth Muscle β Production by Interleukin-12 Increase in Prostaglandin

  1999cites this paper
• Increase in Prostaglandin E2 Production by Interleukin-1β in Arterial Smooth Muscle Cells Derived From Patients With Moyamoya Disease

  1999cites this paper
• Nitric oxide and the proliferation of vascular smooth muscle cells.

  1999cites this paper
• Insulin and Insulin-Like Growth Factor I (IGF-I) Effects on Ca2+ and Nitric Oxide in Diabetes

  1998cites this paper
• Differences in cellular responses to mitogens in arterial smooth muscle cells derived from patients with moyamoya disease.

  1998influential citation
• Modulation of nitric oxide, hydrogen peroxide and cytokine production in a clonal macrophage model by the trichothecene vomitoxin (deoxynivalenol).

  1998cites this paper
• Endothelial cells in physiology and in the pathophysiology of vascular disorders.

  1998cites this paper
• Enhanced coronary vasa vasorum neovascularization in experimental hypercholesterolemia.

  1998cites this paper
• [HgCl2-induced acute renal failure and its pathophysiology].

  1998cites this paper
• Expression of parathyroid hormone/parathyroid hormone-related protein receptor in vascular endothelial cells.

  1998cites this paper
• Does Nitric Oxide Regulate Smooth Muscle Cell Proliferation?

  1998cites this paper
• In vitro toxicity of sodium nitroprusside to human endothelial ECV304 cells.

  1998cites this paper
• Topical modulation of interleukin-1 activity in corneal neovascularization.

  1998cites this paper
• Therapy of cancer metastasis by activation of the inducible nitric oxide synthase

  1998cites this paper
• Nitric oxide in human skin: current status and future prospects.

  1998cites this paper
• Inducible nitric oxide synthase expression in mercury chloride-induced acute tubular necrosis.

  1998cites this paper
• Expression of inducible nitric oxide synthase in rats following subarachnoid hemorrhage.

  1998cites this paper