Position-dependent variegation of globin transgene expression in mice.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1995-06-06

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.92.12.5371PMID 7777514PMCID PMC41696
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Analysis of a 70 kb segment of DNA containing the human zeta and alpha-globin genes linked to their regulatory element (HS-40) in transgenic mice.

  1994cited by this paper
• Position effect variegation at fission yeast centromeres.

  1994cited by this paper
• The basics of basal transcription by RNA polymerase II.

  1994cited by this paper
• Analysis of the developmental and transcriptional potentiation functions of 5'HS2 of the murine beta-globin locus control region in transgenic mice.

  1994cited by this paper
• Mosaic expression of an Hprt transgene integrated in a region of Y heterochromatin.

  1994cited by this paper
• Developmental regulation of human gamma-globin genes in transgenic mice

  1993cited by this paper
• Analysis of the human alpha-globin gene cluster in transgenic mice.

  1993cited by this paper
• The developmental regulation of the human zeta-globin gene in transgenic mice employing beta-galactosidase as a reporter gene.

  1992cited by this paper
• An X-linked human collagen transgene escapes X inactivation in a subset of cells.

  1992cited by this paper
• Analysis of the human alpha globin upstream regulatory element (HS‐40) in transgenic mice.

  1992cited by this paper
• Characterization of the major regulatory element upstream of the human alpha-globin gene cluster

  1991cited by this paper
• Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgenic homozygotes.

  1991cited by this paper
• Clonal coat color variation due to a transforming gene expressed in melanocytes of transgenic mice.

  1991cited by this paper
• DNaseI hypersensitive sites 1, 2 and 3 of the human beta-globin dominant control region direct position-independent expression.

  1990cited by this paper
• A major positive regulatory region located far upstream of the human alpha-globin gene locus.

  1990cited by this paper
• Cellular differentiation in the emerging fetal rat small intestinal epithelium: mosaic patterns of gene expression.

  1989cited by this paper
• Cellular mosaicism in the methylation and expression of hemizygous loci in the mouse.

  1989cited by this paper
• Transgenic mice containing intestinal fatty acid-binding protein-human growth hormone fusion genes exhibit correct regional and cell-specific expression of the reporter gene in their small intestine.

  1988cited by this paper
• Conversion of normal behavior to shiverer by myelin basic protein antisense cDNA in transgenic mice.

  1988cited by this paper
• Position-independent, high-level expression of the human beta-globin gene in transgenic mice.

  1987cited by this paper
• Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma.

  1984cited by this paper
• Commitment to erythroid differentiation by friend erythroleukemia cells: a stochastic analysis.

  1976cited by this paper
• Differentiation in erythroleukemic cells and their somatic hybrids.

  1975cited by this paper
• Position effect variegation in the mouse.

  1974cited by this paper
• A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS.

  1964cited by this paper

• Professor Emma Whitelaw, a pioneer of epigenetic inheritance

  2026cites this paper
• Characterisation of novel regulatory sequences compatible with modular assembly in the diatom Phaeodactylum tricornutum

  2021cites this paper
• Generation of Transgenic Fluorescent Reporter Lines for Studying Hematopoietic Development in the Mouse.

  2021cites this paper
• Expression of functional plant sweet protein thaumatin II in the milk of transgenic mice

  2021cites this paper
• Gene Therapy for Cystic Fibrosis: Progress and Challenges of Genome Editing

  2020cites this paper
• The goat β-casein/CMV chimeric promoter drives the expression of hLF in transgenic goats produced by cell transgene microinjection

  2019cites this paper
• Considerations for the use of Cre recombinase for conditional gene deletion in the mouse lens

  2019cites this paper
• Novel endogenous promoters for genetic engineering of the marine microalga Nannochloropsis gaditana CCMP526

  2019cites this paper
• Versatile multi-transgene expression using improved BAC TG-EMBED toolkit, novel BAC episomes, and BAC-MAGIC

  2019cites this paper
• Delivering on the promise of gene editing for cystic fibrosis

  2018cites this paper
• Disease reduction in aquaculture with genetic and genomic technology: current and future approaches

  2018cites this paper
• Molecular tools to create new strains for mosquito sexing and vector control

  2018cites this paper
• Production of functional human CuZn-SOD and EC-SOD in bitransgenic cloned goat milk

  2018cites this paper
• Monitoring and visualizing microRNA dynamics during live cell differentiation using microRNA-responsive non-viral reporter vectors.

  2017cites this paper
• Advances in Biology and Treatment of Glioblastoma

  2017cites this paper
• Animal Models in Glioblastoma: Use in Biology and Developing Therapeutic Strategies

  2017cites this paper
• kidney and male reproductive system of transgenic mice Expression of an AQP2 Cre recombinase transgene in

  2016cites this paper
• Expression of recombinant human lysozyme in transgenic chicken promotes the growth of Bifidobacterium in the intestine and improves postnatal growth of chicken

  2016cites this paper
• Insertional mutagenesis in PLNR9C transgenic mouse: a case report and a review of the literature on cardiac-specific transgenic expression

  2016cites this paper
• Dual-Reporter β-Cell-Specific Male Transgenic Rats for the Analysis of β-Cell Functional Mass and Enrichment by Flow Cytometry.

  2016cites this paper
• Aquaporin 2-labeled cells differentiate to intercalated cells in response to potassium depletion

  2015cites this paper
• The role of MAR elements in DNA recombination

  2015cites this paper
• Expression of KRASG12V in Zebrafish Gills Induces Hyperplasia and CXCL8-Associated Inflammation

  2015cites this paper
• Generation of transgenic mouse fluorescent reporter lines for studying hematopoietic development.

  2014cites this paper
• Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase.

  2014cites this paper
• Human extracellular superoxide dismutase (EC-SOD) expression in transgenic chicken

  2013cites this paper
• Cells during Differentiation Permissive for Expression in Embryonal Stem -Mediated Extinction of a Retrovirus cis Host

  2013cites this paper
• The use of mouse models to study epigenetics.

  2013cites this paper
• Gene Therapy for Erythroid Metabolic Inherited Diseases

  2013cites this paper
• Gene therapy for methylmalonic aciduria.

  2012cites this paper
• A Role for diaphanous homolog 3 in the Mammalian Auditory System.

  2012cites this paper
• Identification and characterisation of MORC6 as a component of the RNA-directed DNA methylation pathway in Arabidopsis thaliana

  2012cites this paper
• Conditional gene expression systems in the transgenic rat brain

  2012cites this paper
• Production of Antibody by Transgenic Avians

  2011cites this paper
• Transgenerational analysis of transcriptional silencing in zebrafish.

  2011cites this paper
• Transgene Expression and Transgene-Induced Silencing in Diploid and Autotetraploid Arabidopsis

  2011influential citation
• DNA methylation in zebrafish.

  2011cites this paper
• Transgenic and Gene Targeted Models of Dementia

  2011cites this paper
• High-level transgene expression by homologous recombination-mediated gene transfer

  2011cites this paper
• Antibody expression and production

  2011cites this paper
• [Heterochromatin compartments and gene silencing: human hematopoietic differentiation as a model study].

  2010cites this paper
• Analysis of neural circuits in vitro

  2010cites this paper
• the Hematopoietic Compartment Drive Transgene Expression In Vivo Throughout vav Promoter Elements of

  2010cites this paper
• Gene Expression in Mammalian Cells

  2010cites this paper
• Chapter 5 Transgenic and Gene Targeted Models of Dementia

  2010cites this paper
• Laser-evoked synaptic transmission in cultured hippocampal neurons channelrhodopsin-2 delivered by adeno-associated virus

  2009cites this paper
• Laser-evoked synaptic transmission in cultured hippocampal neurons expressing channelrhodopsin-2 delivered by adeno-associated virus.

  2009cites this paper
• aser-evoked synaptic transmission in cultured hippocampal neurons xpressing channelrhodopsin-2 delivered by adeno-associated virus

  2009cites this paper
• Use of MAR Elements to Increase the Production of Recombinant Proteins

  2009cites this paper
• Epitope‐tagging Math5 and Pou4f2: New tools to study retinal ganglion cell development in the mouse

  2009cites this paper
• Translational enhancement of recombinant protein synthesis in transgenic silkworms by a 5'-untranslated region of polyhedrin gene of Bombyx mori Nucleopolyhedrovirus.

  2008cites this paper
• FLUORESCENCE ACTIVATED CELL SORTING OF TRANSIENTLY TRANSFECTED As4.1 CELLS SHOWS RENIN ENHANCER DIRECTS ON/OFF SWITCHING OF RENIN PROMOTER IN VITRO

  2008cites this paper
• A transgenic mouse class-III beta tubulin reporter using yellow fluorescent protein.

  2007cites this paper
• Stem cell plasticity

  2007cites this paper
• A transgenic mouse Class‐III β tubulin reporter using yellow fluorescent protein

  2007cites this paper
• The role of EKLF in human 13-globin gene competition

  2007cites this paper
• Improved embryonic stem cell technologies.

  2007cites this paper
• Maximizing mouse cancer models

  2007cites this paper
• How lifetimes shape epigenotype within and across generations.

  2006cites this paper
• Multiple strategies for gene transfer, expression, knockdown, and chromatin influence in mammalian cell lines and transgenic animals

  2006cites this paper
• Artificial chromosome-based transgenes in the study of genome function

  2006cites this paper
• Characterisation of axon glial interactions in the 2-50 transgenic mouse

  2006cites this paper
• Genomic imprinting in epigenetic of mammals

  2006cites this paper
• Characterisation of a P140K mutant O6‐methylguanine‐DNA‐methyltransferase (MGMT)‐expressing transgenic mouse line with drug‐selectable bone marrow

  2006cites this paper
• Year : 2002 Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat

  2006cites this paper
• Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphoma

  2006cites this paper
• A Transgenic Mouse Model for DNA/RNA Gene Therapy of Human β Thalassemia

  2006cites this paper
• This information is current as Development and Transgene Variegation Transcription Factor 1 Affects Thymocyte Human High Mobility Group Box Williams

  2005cites this paper
• Human High Mobility Group Box Transcription Factor 1 Affects Thymocyte Development and Transgene Variegation1

  2005cites this paper
• Engineering disease resistant cattle w

  2005cites this paper
• Differences of globin transgene expression in stably transfected cell lines and transgenic mice.

  2005cites this paper
• Engineering Disease Resistant Cattle

  2005cites this paper
• High-Level Expression of Single-Chain Fv-Fc Fusion Protein in Serum and Egg White of Genetically Manipulated Chickens by Using a Retroviral Vector

  2005cites this paper
• Spontaneous reactivation of a silent telomeric transgene in a human cell line

  2004cites this paper
• Expression of Human CXCR2 in Murine Neutrophils as a Model for Assessing Cytomegalovirus Chemokine vCXCL-1 Function In Vivo

  2004cites this paper
• Functional Fluorescent Ca2+ Indicator Proteins in Transgenic Mice under TET Control

  2004cites this paper
• Genomic Ly49A Transgenes: Basis of Variegated Ly49A Gene Expression and Identification of a Critical Regulatory Element1

  2004cites this paper
• Genetic and Chromosomal Control of Development

  2004cites this paper
• Regulation of gene expression by the CYP27B1 promoter-study of a transgenic mouse model.

  2004cites this paper
• Gene transfer and expression in mammalian cell lines and transgenic animals.

  2004cites this paper
• General method for the modification of different BAC types and the rapid generation of BAC transgenic mice

  2004cites this paper
• Rapid tamoxifen-induced inactivation of an estrogenic response is accompanied by a localized epigenetic modification but not by mutations

  2004cites this paper
• Identification of a genomic fragment that directs hematopoietic-specific expression of Rac2 and analysis of the DNA methylation profile of the gene locus.

  2004cites this paper
• Do beta-globin, GATA-1,or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?

  2004cites this paper
• Genes and chromosomes: control of development.

  2004cites this paper
• Do transgene arrays form heterochromatin in vertebrates?

  2004cites this paper
• Do β-globin, GATA-1, or EpoR regulatory domains specifically mark erythroid progenitors in transgenic reporter mice?. Authors' reply

  2004cites this paper
• Sensitive flow cytometric analysis reveals a novel type of parent-of-origin effect in the mouse genome.

  2003cites this paper
• High level expression of the bioactive human interleukin-10 in milk of transgenic mice.

  2003cites this paper
• Development of a macromolecular diffusion pathway in the lens

  2003cites this paper
• High-throughput inducible expression of transgenes at the Hprt gene in mouse embryonic stem cells.

  2003cites this paper
• Classification of mature T-cell leukemias

  2003cites this paper
• Development of novel selective cell ablation in the mammary gland and brain to study cell-cell interactions and chemoprevention.

  2003cites this paper
• In vitro and in vivo effects of a multimerized αs1‐casein enhancer on whey acidic protein gene promoter activity

  2003cites this paper
• The regulation of EFG1 in white–opaque switching in Candida albicans involves overlapping promoters

  2003cites this paper
• "Muromics": genomics from the perspective of the laboratory mouse.

  2002cites this paper
• Unhampered Prion Neuroinvasion despite Impaired Fast Axonal Transport in Transgenic Mice Overexpressing Four-Repeat Tau

  2002cites this paper
• Why so many noncoding nucleotides ? The eukaryote genome as an epigenetic machine

  2002cites this paper
• A Functional Chromatin Domain Does Not Resist X Chromosome Inactivation: Silencing of cLys Correlates with Methylation of a Dual Promoter-Replication Origin

  2002cites this paper
• Molecular aspects of embryonic hemoglobin function.

  2002cites this paper