Identification of peptide ligands for malignancy- and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Bioorganic & Medicinal Chemistry

• Publication date

  2005-01-17

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.BMC.2004.09.053PMID 15598577
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Carbohydrate-Recognition and Angiogenesis

  2004cited by this paper
• Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo.

  2004cited by this paper
• Thermodynamic binding studies of bivalent oligosaccharides to galectin-1, galectin-3, and the carbohydrate recognition domain of galectin-3.

  2004cited by this paper
• Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets.

  2004cited by this paper
• The How and Why of Protein-carbohydrate Interaction: A Primer to the Theoretical Concept and a Guide to Application in Drug Design

  2004cited by this paper
• Galectin-3 Precipitates as a Pentamer with Synthetic Multivalent Carbohydrates and Forms Heterogeneous Cross-linked Complexes*

  2004cited by this paper
• Human Galectin-2: Novel Inducer of T Cell Apoptosis with Distinct Profile of Caspase Activation1

  2004cited by this paper
• Interference of the galactose-dependent binding of lectins by novel pentapeptide ligands.

  2004cited by this paper
• Galectin-1(L11A) predicted from a computed galectin-1 farnesyl-binding pocket selectively inhibits Ras-GTP.

  2004cited by this paper
• Chemical Biology of the Sugar Code

  2004cited by this paper
• Refined prognostic evaluation in colon carcinoma using immunohistochemical galectin fingerprinting

  2003cited by this paper
• Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins.

  2003cited by this paper
• First demonstration of differential inhibition of lectin binding by synthetic tri- and tetravalent glycoclusters from cross-coupling of rigidified 2-propynyl lactoside.

  2003cited by this paper
• Structural basis of peptide–carbohydrate mimicry in an antibody-combining site

  2003cited by this paper
• Homodimeric galectin-7 (p53-induced gene 1) is a negative growth regulator for human neuroblastoma cells

  2003cited by this paper
• Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.

  2003cited by this paper
• Detection of ligand- and solvent-induced shape alterations of cell-growth-regulatory human lectin galectin-1 in solution by small angle neutron and x-ray scattering.

  2003cited by this paper
• Combined analysis of tumor growth pattern and expression of endogenous lectins as a prognostic tool in primary testicular cancer and its lung metastases.

  2003cited by this paper
• Tumor galectinology: Insights into the complex network of a family of endogenous lectins

  2003cited by this paper
• New aspects of galectin functionality in nuclei of cultured bone marrow stromal and epidermal cells: biotinylated galectins as tool to detect specific binding sites

  2003cited by this paper
• Adhesion Inhibition of F1C‐Fimbriated Escherichia coli and Pseudomonas aeruginosa PAK and PAO by Multivalent Carbohydrate Ligands

  2003cited by this paper
• Rational design and synthesis of peptide ligands for an anti-carbohydrate antibody and their immunochemical characterization.

  2003cited by this paper
• Molecular Mimicry of Carbohydrates by Peptides

  2002cited by this paper
• Peptide mimotopes as surrogate antigens of carbohydrates in vaccine discovery.

  2002cited by this paper
• Galectin‐1 Modulates Human Glioblastoma Cell Migration into the Brain Through Modifications to the Actin Cytoskeleton and Levels of Expression of Small GTPases

  2002cited by this paper
• CD4+CD7− leukemic T cells from patients with Sézary syndrome are protected from galectin-1-triggered T cell death

  2002cited by this paper
• The Hexapeptide inhibitor of Galbeta 1,3GalNAc-specific alpha 2,3-sialyltransferase as a generic inhibitor of sialyltransferases.

  2002cited by this paper
• Galectinomics: finding themes in complexity.

  2002cited by this paper
• The Hexapeptide Inhibitor of Galβ1,3GalNAc-specific α2,3-Sialyltransferase as a Generic Inhibitor of Sialyltransferases*

  2002cited by this paper
• Characterization of Oligopeptides That Cross-react with Carbohydrate-specific Antibodies by Real Time Kinetics, In-solution Competition Enzyme-linked Immunosorbent Assay, and Immunological Analyses*

  2002cited by this paper
• Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists.

  2002cited by this paper
• Role of galectins in inflammatory and immunomodulatory processes.

  2002cited by this paper
• Intracellular functions of galectins.

  2002cited by this paper
• Galectin-1 Augments Ras Activation and Diverts Ras Signals to Raf-1 at the Expense of Phosphoinositide 3-Kinase*

  2002cited by this paper
• Galectin-8 expression decreases in cancer compared with normal and dysplastic human colon tissue and acts significantly on human colon cancer cell migration as a suppressor

  2002cited by this paper
• Negative Regulation of Neuroblastoma Cell Growth by Carbohydrate-dependent Surface Binding of Galectin-1 and Functional Divergence from Galectin-3*

  2001cited by this paper
• Glycohistochemistry: The Why and How of Detection and Localization of Endogenous Lectins

  2001cited by this paper
• Carbohydrate specificity of a galectin from chicken liver (CG-16).

  2001cited by this paper
• Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures

  2001cited by this paper
• Wedgelike Glycodendrimers as Inhibitors of Binding of Mammalian Galectins to Glycoproteins, Lactose Maxiclusters, and Cell Surface Glycoconjugates

  2001cited by this paper
• Suppression of GD1α ganglioside‐mediated tumor metastasis by liposomalized WHW‐peptide

  2000cited by this paper
• Structural and Functional Consequences of Peptide-Carbohydrate Mimicry

  2000cited by this paper
• Insights into the molecular basis of leukocyte tethering and rolling revealed by structures of P- and E-selectin bound to SLe(X) and PSGL-1.

  2000cited by this paper
• A peptide mimic of E-selectin ligand inhibits sialyl Lewis X-dependent lung colonization of tumor cells.

  2000cited by this paper
• Medicinal chemistry based on the sugar code: fundamentals of lectinology and experimental strategies with lectins as targets.

  2000cited by this paper
• Phage-display technology--finding a needle in a vast molecular haystack.

  1999cited by this paper
• Galectins-1 and -3 and their ligands in tumor biology

  1999cited by this paper
• The 2.15 A crystal structure of CG-16, the developmentally regulated homodimeric chicken galectin.

  1999cited by this paper
• Bovine Heart Galectin-1 Selects a Unique (Syn) Conformation of C-Lactose, a Flexible Lactose Analogue

  1999cited by this paper
• Peptide mimotopes of carbohydrate antigens

  1998cited by this paper
• Animal Lectins as Cell Adhesion Molecules

  1998cited by this paper
• Cluster analysis and display of genome-wide expression patterns.

  1998cited by this paper
• The “One-Bead-One-Compound” Combinatorial Library Method

  1997cited by this paper
• Animal lectins.

  1997cited by this paper
• The "One-Bead-One-Compound" Combinatorial Library Method.

  1997cited by this paper
• Involvement of laser photo-CIDNP (chemically induced dynamic nuclear polarization)-reactive amino acid side chains in ligand binding by galactoside-specific lectins in solution.

  1997cited by this paper
• Neoglycoproteins with the synthetic complex biantennary nonasaccharide or its alpha 2,3/alpha 2,6-sialylated derivatives: their preparation, assessment of their ligand properties for purified lectins, for tumor cells in vitro, and in tissue sections, and their biodistribution in tumor-bearing mice.

  1997cited by this paper
• Concepts of tumor lectinology.

  1997cited by this paper
• Different Architecture of the Combining Site of the Two Chicken Galectins Revealed by Chemical Mapping Studies with Synthetic Ligand Derivatives*

  1996cited by this paper
• NMR-based, molecular dynamics- and random walk molecular mechanics-supported study of conformational aspects of a carbohydrate ligand (Gal beta 1-2Gal beta 1-R) for an animal galectin in the free and in the bound state.

  1996cited by this paper
• Peptide libraries define the fine specificity of anti-polysaccharide antibodies to Cryptococcus neoformans.

  1996cited by this paper
• Differential binding of two chicken beta-galactoside-specific lectins to homologous lymphocyte subpopulations and evidence for inhibitor activity of the dimeric lectin on stimulated T cells.

  1995cited by this paper
• The crystal structure of porcine pancreatic alpha-amylase in complex with the microbial inhibitor Tendamistat.

  1995cited by this paper
• Peptide mimicry of the meningococcal group C capsular polysaccharide.

  1995cited by this paper
• Peptides Which Bind to E-selectin and Block Neutrophil Adhesion (*)

  1995cited by this paper
• Structure of S-lectin, a developmentally regulated vertebrate beta-galactoside-binding protein.

  1994cited by this paper
• Crosslinking of mammalian lectin (galectin-1) by complex biantennary saccharides

  1994cited by this paper
• A PEGA resin for use in the solid-phase chemical–enzymatic synthesis of glycopeptides

  1994cited by this paper
• Identification of a peptide which binds to the carbohydrate-specific monoclonal antibody B3.

  1993cited by this paper
• Libraries of peptides and proteins displayed on filamentous phage.

  1993cited by this paper
• A new type of synthetic peptide library for identifying ligand-binding activity

  1992cited by this paper
• Peptide ligands for a sugar-binding protein isolated from a random peptide library.

  1992cited by this paper
• A family of concanavalin A-binding peptides from a hexapeptide epitope library.

  1992cited by this paper
• A new type of synthetic peptide library for identifying ligand-binding activity

  1992cited by this paper
• Influence of type of linkage and spacer on the interaction of beta-galactoside-binding proteins with immobilized affinity ligands.

  1990cited by this paper
• New coupling reagents in peptide chemistry

  1989cited by this paper
• Antibody-selectable filamentous fd phage vectors: affinity purification of target genes.

  1988cited by this paper
• Solid-phase synthesis of protected peptide fragments using a trialkoxy-diphenyl-methylester resin.

  1987cited by this paper
• Biochemical characterization of endogenous carbohydrate-binding proteins from spontaneous murine rhabdomyosarcoma, mammary adenocarcinoma, and ovarian teratoma.

  1984cited by this paper
• Reactifs de couplage peptidique I (1) - l'hexafluorophosphate de benzotriazolyl N-oxytrisdimethylamino phosphonium (B.O.P.)

  1975cited by this paper

• Selection of Galectin-Binding Ligands from Synthetic Glycopeptide Libraries.

  2023cites this paper
• Routing Nanomolar Protein Cargoes to Lipid Raft‐Mediated/Caveolar Endocytosis through a Ganglioside GM1‐Specific Recognition Tag

  2020cites this paper
• Binding of a Soluble meso-Tetraarylporphyrin to Human Galectin-7 Induces Oligomerization and Modulates Its Pro-Apoptotic Activity.

  2020cites this paper
• Microarrays for the screening and identification of carbohydrate-binding peptides.

  2019cites this paper
• Synthetic Inhibitors of Galectins: Structures and Syntheses

  2018cites this paper
• Blocking Disease Linked Lectins with Multivalent Carbohydrates

  2018cites this paper
• Toward a new and noninvasive diagnostic method of papillary thyroid cancer by using peptide vectorized contrast agents targeted to galectin-1

  2017cites this paper
• Design, Synthesis, and Applications of Galectin Modulators in Human Health

  2014cites this paper
• Recent advances toward the development of inhibitors to attenuate tumor metastasis via the interruption of lectin-ligand interactions.

  2013cites this paper
• UNIVERSIDADE FEDERAL DE UBERLÂNDIA INSTITUTO DE CIÊNCIAS BIOMÉDICAS Programa de Pós-Graduação em Imunologia e Parasitologia Aplicadas

  2012cites this paper
• Inhibition of galectins with small molecules.

  2011cites this paper
• Carbohydrate-mimetic peptides: structural aspects of mimicry and therapeutic implications

  2011cites this paper
• Galectin‐1–Asialofetuin Interaction Is Inhibited by Peptides Containing the Tyr‐Xxx‐Tyr Motif Acting on the Glycoprotein

  2010cites this paper
• Protein information content resides in rare peptide segments.

  2010cites this paper
• Selection of high affinity peptide ligands for detection of circulating antibodies in neurocysticercosis.

  2010cites this paper
• Potential directions for drug development against galectin-7 in cancer

  2009cites this paper
• Peptide microarrays for carbohydrate recognition.

  2009cites this paper
• Potentialdirectionsfordrug developmentagainst galectin-7incancer

  2009cites this paper
• Trichinella spiralis: characterization of phage-displayed specific epitopes and their protective immunity in BALB/c mice.

  2008cites this paper
• Human galectin-2: nuclear presence in vitro and its modulation by quiescence/stress factors.

  2008cites this paper
• Assessing the inhibitory potency of galectin ligands identified from combinatorial (glyco)peptide libraries using surface plasmon resonance spectroscopy.

  2008cites this paper
• Detection of galectin-3 by novel peptidic photoprobes.

  2007cites this paper
• Comparison of two matrices for selective recovery of C595 diabody fragment (dbFv) from Escherichia coli lysates

  2007cites this paper
• Crystallization and preliminary crystallographic analysis of recombinant human galectin-1.

  2007cites this paper
• Discovery of galectin ligands in fully randomized combinatorial one-bead-one-compound (glyco)peptide libraries.

  2007cites this paper
• A Guide to Signaling Pathways Connecting Protein-Glycan Interaction with the Emerging Versatile Effector Functionality of Mammalian Lectins

  2006cites this paper
• Inhibition and Detection of Galectins

  2006cites this paper
• Towards functional glycomics by localization of binding sites for tissue lectins: lectin histochemical reactivity for galectins during diethylstilbestrol-induced kidney tumorigenesis in male Syrian hamster

  2006cites this paper
• Unique sequence and expression profiles of rat galectins-5 and -9 as a result of species-specific gene divergence.

  2006cites this paper
• Survey of the year 2005 commercial optical biosensor literature

  2006cites this paper
• Prognostic Significance of Endogenous Adhesion/Growth-Regulatory Lectins in Lung Cancer

  2005cites this paper
• Survey of the year 2003 commercial optical biosensor literature

  2005cites this paper
• Human galectin-2: expression profiling by RT-PCR/immunohistochemistry and its introduction as a histochemical tool for ligand localization.

  2005cites this paper
• Evidence for lectin activity of a plant receptor-like protein kinase by application of neoglycoproteins and bioinformatic algorithms.

  2005cites this paper