Medicinal chemistry based on the sugar code: fundamentals of lectinology and experimental strategies with lectins as targets.

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Current Medicinal Chemistry

• Publication date

  2000-03-31

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.2174/0929867003375164PMID 10702616
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• Utilization of ELISA technology to measure biological activities of carbohydrates relevant in disease status.

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  1999cited by this paper
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  1999cited by this paper
• Human glycosylation disorders and sugar supplement therapy.

  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1999cited by this paper
• NMR investigations of protein-carbohydrate interactions: refined three-dimensional structure of the complex between hevein and methyl beta-chitobioside.

  1998cited by this paper
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  1998cited by this paper
• Genes and signal molecules involved in the rhizobia-leguminoseae symbiosis.

  1998cited by this paper
• Animal Lectins as Cell Adhesion Molecules

  1998cited by this paper
• Enzyme action in glycoprotein synthesis

  1998cited by this paper
• Substructural specificity and polyvalent carbohydrate recognition by the Entamoeba histolytica and rat hepatic N-acetylgalactosamine/galactose lectins.

  1998cited by this paper
• Galectin-1 Is a Major Receptor for Ganglioside GM1, a Product of the Growth-controlling Activity of a Cell Surface Ganglioside Sialidase, on Human Neuroblastoma Cells in Culture*

  1998cited by this paper
• Legume lectin structure.

  1998cited by this paper
• Plant Lectins – More than Just Tools for Glycoscientists: Occurrence, Structure, and Possible Functions of Plant Lectins

  1998cited by this paper
• Signaling Pathways for Transduction of the Initial Message of the Glycocode into Cellular Responses

  1998cited by this paper
• Computational carbohydrate chemistry: what theoretical methods can tell us

  1998cited by this paper
• Beyond plant lectin histochemistry: preparation and application of markers to visualize the cellular capacity for protein-carbohydrate recognition.

  1998cited by this paper
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  1998cited by this paper
• Recent Advances in the Biochemistry of Sphingolipidoses

  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Detection of Inflammation- and Neoplasia-Associated Alterations in Human Large Intestine Using Plant/Invertebrate Lectins, Galectin-1 and Neoglycoproteins

  1998cited by this paper
• Lectin Ligands: New Insights into Their Conformations and Their Dynamic Behavior and the Discovery of Conformer Selection by Lectins

  1998cited by this paper
• Oligoglucoside elicitor‐mediated activation of plant defense

  1998cited by this paper
• Factors controlling the glycosylation potential of the Golgi apparatus.

  1998cited by this paper
• Structure of the O-specific polysaccharide of a serologically separate Proteus penneri strain 22.

  1998cited by this paper
• Applications of Lectins and Neoglycoconjugates in Histology and Pathology

  1998cited by this paper
• Conformer selection and differential restriction of ligand mobility by a plant lectin--conformational behaviour of Galbeta1-3GlcNAcbeta1-R, Galbeta1-3GalNAcbeta1-R and Galbeta1-2Galbeta1-R' in the free state and complexed with galactoside-specific mistletoe lectin as revealed by random-walk and conf

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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
• Modular organization of carbohydrate recognition domains in animal lectins.

  1997cited by this paper
• Involvement of laser photo-CIDNP (chemically induced dynamic nuclear polarization)-reactive amino acid side chains in ligand binding by galactoside-specific lectins in solution.

  1997cited by this paper
• Animal lectins.

  1997cited by this paper
• The structure and function of a soybean beta-glucan-elicitor-binding protein.

  1997cited by this paper
• Neoglycoproteins with the synthetic complex biantennary nonasaccharide or its alpha 2,3/alpha 2,6-sialylated derivatives: their preparation, assessment of their ligand properties for purified lectins, for tumor cells in vitro, and in tissue sections, and their biodistribution in tumor-bearing mice.

  1997cited by this paper
• Oligosaccharide structures: theory versus experiment.

  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
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  1997cited by this paper
• Concepts of tumor lectinology.

  1997cited by this paper
• Structural basis of lectin-carbohydrate recognition.

  1996cited by this paper
• Oligosaccharide anti-infective agents.

  1996cited by this paper
• NMR-based, molecular dynamics- and random walk molecular mechanics-supported study of conformational aspects of a carbohydrate ligand (Gal beta 1-2Gal beta 1-R) for an animal galectin in the free and in the bound state.

  1996cited by this paper
• Sialic acids structure-analysis-metabolism-occurrence-recognition.

  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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  1995cited by this paper
• Galactofuranose-containing glycoconjugates in trypanosomatids.

  1995cited by this paper
• [Protein-carbohydrate recognition. Foundation and medical application with illustrations of tumor lectin studies].

  1995cited by this paper
• Side‐chain conformational entropy in protein folding

  1995cited by this paper
• The interaction of hevein with N-acetylglucosamine-containing oligosaccharides. Solution structure of hevein complexed to chitobiose.

  1995cited by this paper
• I-type Lectins (*)

  1995cited by this paper
• Microbial recognition of target-cell glycoconjugates.

  1995cited by this paper
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  1994cited by this paper
• Carbohydrate binding activities of Bradyrhizobium japonicum. III. Lectin expression, bacterial binding, and nodulation efficiency.

  1994cited by this paper
• [Synthesis of antibiotic-glycoside conjugates as potential ligands for bacterial lectins].

  1994cited by this paper
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  1994cited by this paper
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  1994cited by this paper
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• Non-carbohydrate binding partners/domains of animal lectins.

  1994cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
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  1993cited by this paper
• Reverse lectin histochemistry: design and application of glycoligands for detection of cell and tissue lectins.

  1993cited by this paper
• Ribosome-inactivating proteins from plants.

  1993cited by this paper
• Attachment of Helicobacter pylori to human gastric epithelium mediated by blood group antigens.

  1993cited by this paper
• Ligand binding characteristics of the major mistletoe lectin.

  1992cited by this paper
• Rhizobium–plant signal exchange

  1992cited by this paper
• Novel oligosaccharide constituents of the cellulase complex of Bacteroides cellulosolvens.

  1992cited by this paper
• Novel N-linked oligo-mannose type oligosaccharides containing an alpha-D-galactofuranosyl linkage found in alpha-D-galactosidase from Aspergillus niger.

  1992cited by this paper
• Studies of the molecular recognition of synthetic methyl beta-lactoside analogues by Ricinus communis agglutinin.

  1992cited by this paper
• Structural features of the sulphated polysaccharide from a green seaweed, Spongomorpha indica.

  1991cited by this paper
• Lysosomal storage diseases.

  1991cited by this paper
• Studies on the molecular recognition of synthetic methyl beta-lactoside analogs by ricin, a cytotoxic plant lectin.

  1991cited by this paper
• Structure of ricin B‐chain at 2.5 Å resolution

  1991cited by this paper
• Heparin binding lectin of human placenta as a tool for histochemical ligand localization and isolation.

  1991cited by this paper
• Detection and functions of mammalian lectins--with emphasis on membrane lectins.

  1991cited by this paper
• Neoglycoproteins as tools in glycohistochemistry.

  1991cited by this paper
• Glycoprotein glycans that inhibit adhesion of Escherichia coli mediated by K99 fimbriae: treatment of experimental colibacillosis

  1990cited by this paper
• The price of lost freedom: entropy of bimolecular complex formation.

  1989cited by this paper

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  2018cites this paper
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  2017cites this paper
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  2015cites this paper
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• Dietary lectins as disease causing toxicants.

  2009cites this paper
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  2009cites this paper
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  2008cites this paper
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  2008influential citation
• Interactions of Carbohydrates in Aqueous Solutions

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  2007cites this paper
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  2007cites this paper
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  2007cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2006cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
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  2005cites this paper
• Lectin histochemical investigations of the distal gut of chicks with special emphasis on the follicle-associated epithelium.

  2005cites this paper
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  2005cites this paper
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  2004cites this paper
• Interference of the galactose-dependent binding of lectins by novel pentapeptide ligands.

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
• Determination of modulation of ligand properties of synthetic complex-type biantennary N-glycans by introduction of bisecting GlcNAc in silico, in vitro and in vivo.

  2004cites this paper
• Persubstituted cyclodextrin-based glycoclusters as inhibitors of protein-carbohydrate recognition using purified plant and mammalian lectins and wild-type and lectin-gene-transfected tumor cells as targets.

  2004cites this paper
• Liquid chromatographic and mass spectrometric analysis of human serum acid alpha-1-glycoprotein.

  2004cites this paper
• The sugar code in drug delivery.

  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
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  2004cites this paper
• Suitability of binary mixtures of water with aprotic solvents to turn hydroxyl protons of carbohydrate ligands into conformational sensors in NOE and transferred NOE experiments

  2003cites this paper
• Unique conformer selection of human growth-regulatory lectin galectin-1 for ganglioside GM1 versus bacterial toxins.

  2003cites this paper