Prolonged persistence of substantial volumes of potentially viable brain tissue after stroke: a correlative PET-CT study with voxel-based data analysis.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Stroke

• Publication date

  1996-04-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1161/01.STR.27.4.599PMID 8614914
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The 15O continuous-inhalation method: Correction for intravascular signal using C15O

  2004cited by this paper
• Treatment of acute ischemic stroke. Challenging the concept of a rigid and universal time window.

  1995cited by this paper
• Sequential studies of severely hypometabolic tissue volumes after permanent middle cerebral artery occlusion. A positron emission tomographic investigation in anesthetized baboons.

  1995cited by this paper
• Progression of atrophy of the corpus callosum with deterioration of cerebral cortical oxygen metabolism after carotid artery occlusion: a follow up study with MRI and PET.

  1995cited by this paper
• Contralateral cerebellar hypometabolism: a predictor for stroke outcome?

  1994cited by this paper
• PET Study of Changes in Local Brain Hemodynamics and Oxygen Metabolism after Unilateral Middle Cerebral Artery Occlusion in Baboons

  1993cited by this paper
• Rapid Automated Algorithm for Aligning and Reslicing PET Images

  1992cited by this paper
• Pathophysiology of acute ischaemic stroke.

  1992cited by this paper
• Regional cerebral oxygen consumption, blood flow, and blood volume in healthy human aging.

  1992cited by this paper
• Progressive Derangement of Periinfarct Viable Tissue in Ischemic Stroke

  1992cited by this paper
• Ischemic Penumbra and Neuronal Death: Comments on the Therapeutic Window in Acute Stroke with Particular Reference to Thrombolytic Therapy

  1991cited by this paper
• Transhemispheric diaschisis. A review and comment.

  1991cited by this paper
• Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.

  1991cited by this paper
• Pathophysiology of Acute Cerebral Ischemia: PET Studies in Humans

  1991cited by this paper
• Placebo-controlled trial of nimodipine in the treatment of acute ischemic cerebral infarction.

  1990cited by this paper
• The Effect of Nimodipine on the Evolution of Human Cerebral Infarction Studied by PET

  1989cited by this paper
• Neuronal network disturbance after focal ischemia in rats.

  1989cited by this paper
• Measurements of acute cerebral infarction: lesion size by computed tomography.

  1989cited by this paper
• Neurological deficit and cerebral infarction after temporary middle cerebral artery occlusion in unanesthetized cats.

  1986cited by this paper
• A Stereotactic Method of Anatomical Localization for Positron Emission Tomography

  1985cited by this paper
• Cerebral Blood Flow and Cerebral Metabolic Rate of Oxygen Requirements for Cerebral Function and Viability in Humans

  1985cited by this paper
• Selective Necrosis and Total Necrosis in Focal Cerebral ischemia. Neuropathologic Observations on Experimental Middle Cerebral Artery Occlusion in the Macaque Monkey

  1984cited by this paper
• Serial observations on the pathophysiology of acute stroke. The transition from ischaemia to infarction as reflected in regional oxygen extraction.

  1983cited by this paper
• Coupling between regional blood flow and oxygen utilization in the normal human brain. A study with positron tomography and oxygen 15.

  1983cited by this paper
• Cerebral Oxygen Metabolism and Blood Flow in Human Cerebral Ischemic Infarction

  1982cited by this paper
• Thresholds in cerebral ischemia - the ischemic penumbra.

  1981cited by this paper
• Thresholds of focal cerebral ischemia in awake monkeys.

  1981cited by this paper
• Quantitative Measurement of Regional Cerebral Blood Flow and Oxygen Metabolism in Man Using 15O and Positron Emission Tomography: Theory, Procedure, and Normal Values

  1980cited by this paper

• [Advanced imaging diagnosis and therapeutic strategies for ischemic stroke].

  2026cites this paper
• Fifty Years of Deciphering Stroke Pathophysiology.

  2025cites this paper
• Stroke: Current State of the Problem

  2025cites this paper
• Neuroimaging of motor recovery after ischemic stroke − functional reorganization of motor network

  2024cites this paper
• Predictive value of follow-up infarct volume on functional outcomes in middle cerebral artery M2 segment vessel occlusion stroke treated with mechanical thrombectomy

  2024cites this paper
• Mechanical thrombectomy for large vessel occlusion strokes beyond 24 hours

  2023cites this paper
• Endovascular thrombectomy beyond 24 hours from last known well: a systematic review with meta-analysis

  2023cites this paper
• Advanced Imaging in the Current Era of Acute Reperfusion Therapies

  2023cites this paper
• Exercise improved P2Y12-regulated microglial dynamics during stroke via endocannabinoid signaling

  2023influential citation
• Is the optimal Tmax threshold identifying perfusion deficit volumes variable across MR perfusion software packages? A pilot study

  2023cites this paper
• Final infarct prediction in acute ischemic stroke

  2022influential citation
• The Cystine/Glutamate Antiporter, System xc–, Contributes to Cortical Infarction After Moderate but Not Severe Focal Cerebral Ischemia in Mice

  2022cites this paper
• Effects of dichloromethane extraction from Piper nigrum L. and P. longum L. on the expression of autophagy-related proteins in ischemic stroke.

  2022cites this paper
• Endovascular recanalization in patients with severely disabling non-acute ischemic stroke

  2022cites this paper
• Clinical Imaging of the Penumbra in Ischemic Stroke: From the Concept to the Era of Mechanical Thrombectomy

  2022cites this paper
• The core/penumbra model: implications for acute stroke treatment and patient selection in 2021

  2021cites this paper
• Ischemic Penumbra: A Personal View

  2021cites this paper
• Neurological Applications of Positron Emission Tomography Imaging in Healthcare and Research

  2021cites this paper
• Diversity of Reactive Astrogliosis in CNS Pathology: Heterogeneity or Plasticity?

  2021cites this paper
• A precision medicine framework for personalized simulation of hemodynamics in cerebrovascular disease

  2020cites this paper
• ASL perfusion in acute ischemic stroke: The value of CBF in outcome prediction.

  2020cites this paper
• Predictive value of Alberta stroke program early CT score for perfusion weighted imaging - diffusion weighted imaging mismatch in stroke with middle cerebral artery occlusion

  2020cites this paper
• A New Era of Extended Time Window Acute Stroke Interventions Guided by Imaging

  2020cites this paper
• Imaging Guidance for Therapeutic Delivery: The Dawn of Neuroenergetics

  2020cites this paper
• Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptake

  2020cites this paper
• Impact of stroke co-morbidities on cortical collateral flow following ischaemic stroke

  2020cites this paper
• The ischemic penumbra: From concept to reality

  2020cites this paper
• Positron Emission Tomography After Ischemic Brain Injury: Current Challenges and Future Developments

  2020cites this paper
• Cerebral collaterals in acute ischaemia: Implications for acute ischaemic stroke patients receiving reperfusion therapy

  2020cites this paper
• Microglia monitor and protect neuronal function through specialized somatic purinergic junctions

  2019cites this paper
• Brain-Derived Extracellular Vesicles are Highly Enriched in the Prion Protein and Its C1 Fragment: Relevance for Cellular Uptake and Implications in Stroke

  2019cites this paper
• Specific treatment of acute ischemic stroke

  2019cites this paper
• Microglia Monitor and Protect Neuronal Function Via Specialized Somatic Purinergic Junctions in an Activity-Dependent Manner

  2019cites this paper
• An acute stroke CT imaging algorithm incorporating automated perfusion analysis

  2019cites this paper
• Microglia monitor and protect neuronal function via specialized somatic purinergic junctions

  2019cites this paper
• Infarct Evolution in a Large Animal Model of Middle Cerebral Artery Occlusion

  2019influential citation
• Penumbra detection in acute stroke with perfusion magnetic resonance imaging: Validation with 15O‐positron emission tomography

  2019cites this paper
• Neuroimaging

  2019cites this paper
• Oxygen metabolism MRI – A comparison with perfusion imaging in a rat model of MCA branch occlusion and reperfusion

  2019cites this paper
• Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) Magnetic Resonance Metabolic Imaging Identifies the Penumbra Following Acute Ischemic Stroke

  2018cites this paper
• Is Perfusion MRI without Deconvolution Reliable for Mismatch Detection in Acute Stroke? Validation with 15O-Positron Emission Tomography

  2018cites this paper
• Molecular Communication of a Dying Neuron in Stroke

  2018cites this paper
• A new era for stroke therapy: Integrating neurovascular protection with optimal reperfusion

  2018cites this paper
• Transient Ischemic Attack and Stroke

  2018cites this paper
• Collateral Clock Is More Important Than Time Clock for Tissue Fate: A Natural History Study of Acute Ischemic Strokes

  2018cites this paper
• Fast Versus Slow Progressors of Infarct Growth in Large Vessel Occlusion Stroke: Clinical and Research Implications

  2017influential citation
• Imaging Approaches to Stroke and Neurovascular Disease.

  2017cites this paper
• A New Paradigm in Protecting Ischemic Brain: Preserving the Neurovascular Unit Before Reperfusion

  2017cites this paper
• Oxygen metabolism in acute ischemic stroke

  2017cites this paper
• Do We Have a Chance to Translate Bench-top Results to the Clinic Adequately? An Opinion

  2017cites this paper
• Metabolic Imaging of the Neurovascular Interface in Cerebrovascular Disease using Positron Emission Tomography

  2017cites this paper
• MRI-based mismatch detection in acute ischemic stroke: Optimal PWI maps and thresholds validated with PET

  2017cites this paper
• Imaging Approaches to Stroke and Neurovascular Disease

  2017cites this paper
• Animal models of ischaemic stroke and characterisation of the ischaemic penumbra

  2017influential citation
• Dosage Calculation for Intravenous Thrombolysis of Ischemic Stroke: To Weigh or to Estimate

  2017cites this paper
• PET imaging of the neurovascular interface in cerebrovascular disease

  2017cites this paper
• Successful outcome after endovascular thrombolysis for acute ischemic stroke with basis on perfusion-diffusion mismatch after 24 h of symptoms onset

  2016cites this paper
• 55 – Pharmacologic Modification of Acute Cerebral Ischemia

  2016cites this paper
• What is the relationship among penumbra volume, collaterals, and time since onset in the first 6 h after acute ischemic stroke?

  2016cites this paper
• ASPECTS (Alberta Stroke Program Early CT Score) Assessment of the Perfusion–Diffusion Mismatch

  2016cites this paper
• The Ischemic Penumbra and Cell Survival

  2015cites this paper
• Current knowledge on the neuroprotective and neuroregenerative properties of citicoline in acute ischemic stroke

  2015cites this paper
• Quantifying cerebral blood flow of both the micro- and macrovascular system using perfusion computed tomography

  2015cites this paper
• Devenir du mismatch perfusion/diffusion chez les patients non recanalisés après thrombolyse

  2015cites this paper
• Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue

  2015cites this paper
• 3 – Cerebral Blood Flow and Metabolism: Regulation and Pathophysiology in Cerebrovascular Disease

  2015cites this paper
• Translational Perspectives on Perfusion–Diffusion Mismatch in Ischemic Stroke

  2015cites this paper
• The Modulation of the Cystic Fibrosis Transmembrane Conductance Regulator Protein by Sphingosine-1-Phosphate in the Cerebral Microvascular System

  2014cites this paper
• Acute Blood Pressure Reduction in Patients With Intracerebral Hemorrhage Does Not Result in Borderzone Region Hypoperfusion

  2014cites this paper
• Metabolic Imaging of Ischemic Stroke: The Present and Future

  2014cites this paper
• Imaging of cerebral ischemia: from acute stroke to chronic disorders.

  2014cites this paper
• Collaterals: An Important Determinant of Prolonged Ischemic Penumbra Versus Rapid Cerebral Infarction?

  2014cites this paper
• Meta-analysis of preclinical studies of mesenchymal stromal cells for ischemic stroke

  2014cites this paper
• Present and

  2014cites this paper
• MRI Biomarkers in Acute Ischemic Stroke: A Conceptual Framework and Historical Analysis

  2013cites this paper
• Pathophysiology of post-stroke hyperglycaemia and brain arterial patency

  2013cites this paper
• Pre- and Post-Angioplasty Perfusion CT with Acetazolamide Challenge in Patients with Unilateral Cerebrovascular Stenotic Disease

  2013cites this paper
• Sodium MRI of the Human Brain: Application to Ischemic Stroke and the Development of Multiple Quantum Filtering

  2013cites this paper
• ESC-BRAIN: Experimental and Clinical Stroke Research - Do They Connect?

  2013cites this paper
• Infarct Volume Is a Pivotal Biomarker After Intra-Arterial Stroke Therapy

  2012cites this paper
• Outcome Prediction within Twelve Hours after Severe Traumatic Brain Injury by Quantitative Cerebral Blood Flow

  2012cites this paper
• Multimodal MRI of Experimental Stroke

  2012cites this paper
• Imaging the pathophysiology of ischemic cerebrovascular disease

  2012cites this paper
• The ischemic penumbra: how does tissue injury evolve?

  2012cites this paper
• Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-&agr;–Dependent Activation of Sphingosine-1-Phosphate Signaling

  2012cites this paper
• Oxygen metabolism, oxygen extraction and positron emission tomography: Historical perspective and impact on basic and clinical neuroscience

  2012cites this paper
• Timing of thrombolysis for acute ischemic stroke: “timing is everything” or “everyone is different”

  2012cites this paper
• Oxygen challenge MRI: development of a novel technique and application to acute stroke patients

  2012cites this paper
• Change in Cortical Vessel Signs on Susceptibility-Weighted Images after Full Recanalization in Hyperacute Ischemic Stroke

  2012cites this paper
• Imaging for Endovascular Stroke Therapy

  2011cites this paper
• Spatiotemporal Characteristics of Postischemic Hyperperfusion with Respect to Changes in T1, T2, Diffusion, Angiography, and Blood–Brain Barrier Permeability

  2011cites this paper
• Relationship between inflammatory reaction and ischemic injury of caudate-putamen in rats: inflammatory reaction and brain ischemia

  2011cites this paper
• Cerebral Blood Flow Measurement in the Assessment of Post-Traumatic Cerebral Contusions

  2011cites this paper
• Advanced neuroimaging in acute ischemic stroke: extending the time window for treatment.

  2011cites this paper
• Cerebral Blood Flow and Metabolism in Human Cerebrovascular Disease

  2011cites this paper
• The Clinical Ischemic Penumbra

  2011cites this paper
• Transient Focal Ischemia in the Rat Modest MRI Signal Intensity Changes Precede Delayed Cortical Necrosis After

  2011cites this paper
• Imaging-based treatment selection for intravenous and intra-arterial stroke therapies: a comprehensive review

  2011cites this paper
• Perfusion MRI of Acute Stroke

  2011cites this paper
• Preclinical Drug Evaluation for Combination Therapy in Acute Stroke Using Systematic Review, Meta-Analysis, and Subsequent Experimental Testing

  2011cites this paper