Bmp4 gene is expressed at the putative site of fusion in the midfacial region.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Differentiation; research in biological diversity

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1046/J.1432-0436.2003.710304.XPMID 12694205
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Developmental cell death: morphological diversity and multiple mechanisms

  2004cited by this paper
• Programmed cell death is required for palate shelf fusion and is regulated by retinoic acid.

  2002influential reference
• Phenotypic and molecular analyses of A/WySn mice.

  2001cited by this paper
• Noggin and retinoic acid transform the identity of avian facial prominences

  2001cited by this paper
• The Twirler mouse, a model for the study of cleft lip and palate.

  2000cited by this paper
• Epithelial-mesenchymal transformation is the mechanism for fusion of the craniofacial primordia involved in morphogenesis of the chicken lip.

  2000influential reference
• Bulging medial edge epithelial cells and palatal fusion.

  2000influential reference
• Shaping limbs by apoptosis.

  1998cited by this paper
• Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development.

  1997cited by this paper
• Ectopic application of recombinant BMP-2 and BMP-4 can change patterning of developing chick facial primordia.

  1997cited by this paper
• Transforming growth factor–β3 is required for secondary palate fusion

  1995cited by this paper
• Expression of bone morphogenetic protein-4 (BMP-4), bone morphogenetic protein-7 (BMP-7), fibroblast growth factor-8 (FGF-8) and sonic hedgehog (SHH) during branchial arch development in the chick.

  1995cited by this paper
• Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse.

  1995cited by this paper
• Abnormal lung development and cleft palate in mice lacking TGF–β3 indicates defects of epithelial–mesenchymal interaction

  1995cited by this paper
• Deficient and delayed primary palatal fusion and mesenchymal bridge formation in cleft lip-liable strains of mice.

  1995influential reference
• An overview of epithelio-mesenchymal transformation.

  1995cited by this paper
• Inhibition of TGF-beta 3 (but not TGF-beta 1 or TGF-beta 2) activity prevents normal mouse embryonic palate fusion.

  1995cited by this paper
• Transforming growth factor-beta 3 is required for secondary palate fusion.

  1995cited by this paper
• Deficient and delayed primary palatal fusion and mesenchymal bridge formation in cleft lip-liable strains of mice.

  1995cited by this paper
• The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

  1994cited by this paper
• Expression patterns of the bone morphogenetic protein genes Bmp‐4 and Bmp‐2 in the developing chick face suggest a role in outgrowth of the primordia

  1994cited by this paper
• The fate of medial edge epithelial cells during palatal fusion in vitro: an analysis by DiI labelling and confocal microscopy.

  1992cited by this paper
• Molecular and morphologic changes during the epithelial-mesenchymal transformation of palatal shelf medial edge epithelium in vitro.

  1991cited by this paper
• Palate development.

  1988influential reference
• The prevalence of cleft lip and palate in the Japanese: their birth prevalence in 40,304 infants born during 1982.

  1987cited by this paper
• Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse.

  1987cited by this paper
• Light and electron microscopic study of fusion of facial prominences

  1985cited by this paper
• Light and electron microscopy study of fusion of facial prominences. A distinctive type of superficial cells at the contact sites.

  1985influential reference
• The Epithelium-Connective Tissue Interface During Closure of the Secondary Palate in Rodent Embryos

  1969cited by this paper
• Pathogenesis of cleft lip and its relation to embryonic face shape in A-J and C57BL mice.

  1968cited by this paper
• Onset of the acquired potentiality for fusion in the palatal shelves of rats.

  1966cited by this paper

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  2024cites this paper
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  2024cites this paper
• Ethnic Differences in the Brazilian Population Influence the Impact of BMP4 Genetic Variants on Susceptibility of Nonsyndromic Orofacial Clefts

  2023cites this paper
• Identification by RNA‐Seq of let‐7 clusters as prenatal biomarkers for nonsyndromic cleft lip with palate

  2022cites this paper
• Preliminary Analysis of Transcriptomic Variations in Esrp1/Sox2 Double Transgenic Mouse Embryo Facial Prominences in Search of Esrp1 Targets Responsible for Cleft Lip and/or Palate Pathogenesis

  2022cites this paper
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  2022cites this paper
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  2021cites this paper
• Gene-gene interactions between BMP4 and ARHGAP29 among non-syndromic cleft lip only (NSCLO) trios from western Han Chinese population.

  2020cites this paper
• Msx1 deficiency interacts with hypoxia and induces a morphogenetic regulation during lip development.

  2020cites this paper
• Cellular and developmental basis of orofacial clefts

  2020cites this paper
• Association between BMP4 gene polymorphisms and cleft lip with or without cleft palate in a population from South China.

  2018cites this paper
• BMP4 rs17563 polymorphism and nonsyndromic cleft lip with or without cleft palate

  2017cites this paper
• Matching genotype to phenotype in a detailed assessment of lip morphology

  2016cites this paper
• Variation, Genetics, and Evolution of the Primate Craniofacial Complex

  2015cites this paper
• Expresión de los genes "Serrate1" y "Notch1" durante el desarrollo del tercio medio facial del embrión de pollo

  2015cites this paper
• Diversity in primary palate ontogeny of amniotes revealed with 3D imaging

  2015cites this paper
• Recent insights into the morphological diversity in the amniote primary and secondary palates

  2015cites this paper
• Association between BMP4 rs17563 Polymorphism and NSCL/P Risk: A Meta-Analysis

  2015cites this paper
• Single nucleotide polymorphism of bone morphogenetic protein 4 gene: A risk factor of non-syndromic cleft lip with or without palate

  2015influential citation
• BMP 4 Gene and Pathophysiology of Cleft Lip and Palate

  2014cites this paper
• Association of BMP4 polymorphisms with non-syndromic cleft lip with or without cleft palate and isolated cleft palate in Latvian and Lithuanian populations.

  2014cites this paper
• Role of facial shape in mouse models of cleft lip and palate

  2014cites this paper
• Classifying Common Oral Clefts: A New Approach after Descriptive Registration

  2014cites this paper
• Dissecting the role of the major cleft gene, IRF6, in primary palatal epithelia

  2013cites this paper
• BMP4 Polymorphism is Associated with Nonsyndromic Oral Cleft in a Brazilian Population

  2013cites this paper
• Pattern and polarity in the development and evolution of the gnathostome jaw: both conservation and heterotopy in the branchial arches of the shark, Scyliorhinus canicula.

  2013cites this paper
• Preliminary Analysis of the Nonsynonymous Polymorphism rs17563 in BMP4 Gene in Brazilian Population Suggests Protection for Nonsyndromic Cleft Lip and Palate

  2012cites this paper
• Roles of BMP signaling pathway in lip and palate development.

  2012cites this paper
• Geminin Is Required for Epithelial to Mesenchymal Transition at Gastrulation

  2012cites this paper
• Isolation of Epithelial Cells in the Developing Primary Lip and Palate

  2011influential citation
• Activation of the PI3K/Akt Pathway Mediates Bone Morphogenetic Protein 2-Induced Invasion of Pancreatic Cancer Cells Panc-1

  2011cites this paper
• Risk variants in BMP4 promoters for nonsyndromic cleft lip/palate in a Chilean population

  2011cites this paper
• EXPRESSION PROFILING OF TGFß SUPERFAMILY GENES IN DEVELOPING OROFACIAL TISSUE

  2011cites this paper
• Palate morphogenesis: current understanding and future directions.

  2010cites this paper
• Association Between Bone Morphogenetic Protein 4 Gene Polymorphisms with Nonsyndromic Cleft Lip with or without Cleft Palate in a Chilean Population

  2010cites this paper
• Differentiation of embryonic stem cells into hepatocytes that coexpress coagulation factors VIII and IX

  2010cites this paper
• Pancreatic cancer and epithelial to mesenchymal transition (EMT) -The role of BMP signal and its target gene MSX2 in EMT of pancreatic carcinoma cells-

  2010cites this paper
• Analysis of interactions between genetic variants of BMP4 and environmental factors with nonsyndromic cleft lip with or without cleft palate susceptibility.

  2010cites this paper
• Flrt2 and Flrt3 have overlapping and non-overlapping expression during craniofacial development.

  2009cites this paper
• Neuroembryology and functional anatomy of craniofacial clefts

  2009cites this paper
• A induces craniofacial malformation in mice acting on Dlx 5 gene expression

  2009cites this paper
• BMP signaling dynamics in embryonic orofacial tissue

  2008cites this paper
• Neural tube programming and the pathogenesis of craniofacial clefts, part II: mesenchyme, pharyngeal arches, developmental fields; and the assembly of the human face.

  2008cites this paper
• Mouse genetic models of cleft lip with or without cleft palate.

  2008cites this paper
• The etiopathogenesis of cleft lip and cleft palate: usefulness and caveats of mouse models.

  2008influential citation
• Association of Bone Morphogenetic Protein 4 Gene Polymorphisms with Nonsyndromic Cleft Lip with or without Cleft Palate in Chinese Children

  2008cites this paper
• In vitro differentiation of embryonic stem cells into hepatocytes induced by fibroblast growth factors and bone morphological protein-4.

  2007cites this paper
• Three -dimensional morphometric analysis of the craniofacial complex in the unaffected relatives of individuals with nonsyndromic orofacial clefts

  2007cites this paper
• RNA interference of Bmp-4 and midface development in postimplantation mouse embryos.

  2007cites this paper
• Developmental field reassignment in unilateral cleft lip: Reconstruction of the premaxilla

  2007cites this paper
• Bone morphogenetic protein 4 induces epithelial‐mesenchymal transition through MSX2 induction on pancreatic cancer cell line

  2007cites this paper
• BMP signalling in craniofacial development.

  2006cites this paper
• Molecular fingerprinting of BMP2- and BMP4-treated embryonic maxillary mesenchymal cells.

  2006cites this paper
• Sox9 mRNA expression in the developing palate and craniofacial muscles and skeletons

  2006cites this paper
• Expression profiling of transforming growth factor beta superfamily genes in developing orofacial tissue.

  2006cites this paper
• Expression of Wnt9b and activation of canonical Wnt signaling during midfacial morphogenesis in mice

  2006cites this paper
• Development of the upper lip: Morphogenetic and molecular mechanisms

  2006cites this paper
• Trp53 Affects the Developmental Anomaly of Clefts of the Palate in Irradiated Mouse Embryos but not Clefts of the Lip with or without the Palate

  2006cites this paper
• Msx1 and Dlx5 act independently in development of craniofacial skeleton, but converge on the regulation of Bmp signaling in palate formation.

  2006cites this paper
• Identification of Markers of the Midface

  2005cites this paper
• Aspectos Moleculares en la Formación de la Cara y del Paladar

  2005cites this paper
• The carniofacial phenotype of fibrodysplasia ossificans progressiva

  2005cites this paper
• Gene and protein expression of transforming growth factor beta 2 gene during murine primary palatogenesis.

  2005cites this paper
• [Differential expression of Bmp2, Bmp4 and Bmp3 in embryonic development of mouse anterior and posterior palate].

  2005cites this paper
• The Study of Phenotypic Variability: An Emerging Research Agenda for Understanding the Developmental—Genetic Architecture Underlying Phenotypic Variation

  2005cites this paper
• Expression of Gja1 correlates with the phenotype observed in oculodentodigital syndrome/type III syndactyly

  2004cites this paper
• Perspectives on growth factors and orofacial development.

  2004cites this paper
• Taking it to the max: The genetic and developmental mechanisms coordinating midfacial morphogenesis and dysmorphology

  2004cites this paper