Improved Tolerance to Various Abiotic Stresses in Transgenic Sweet Potato (Ipomoea batatas) Expressing Spinach Betaine Aldehyde Dehydrogenase

Abiotic stresses are critical delimiters for the increased productivity and cultivation expansion of sweet potato (Ipomoea batatas), a root crop with worldwide importance. The increased production of glycine betaine (GB) improves plant tolerance to various abiotic stresses without strong phenotypic changes, providing a feasible approach to improve stable yield production under unfavorable conditions. The gene encoding betaine aldehyde dehydrogenase (BADH) is involved in the biosynthesis of GB in plants, and the accumulation of GB by the heterologous overexpression of BADH improves abiotic stress tolerance in plants. This study is to improve sweet potato, a GB accumulator, resistant to multiple abiotic stresses by promoted GB biosynthesis. A chloroplastic BADH gene from Spinacia oleracea (SoBADH) was introduced into the sweet potato cultivar Sushu-2 via Agrobacterium-mediated transformation. The overexpression of SoBADH in the transgenic sweet potato improved tolerance to various abiotic stresses, including salt, oxidative stress, and low temperature. The increased BADH activity and GB accumulation in the transgenic plant lines under normal and multiple environmental stresses resulted in increased protection against cell damage through the maintenance of cell membrane integrity, stronger photosynthetic activity, reduced reactive oxygen species (ROS) production, and induction or activation of ROS scavenging by the increased activity of free radical-scavenging enzymes. The increased proline accumulation and systemic upregulation of many ROS-scavenging genes in stress-treated transgenic plants also indicated that GB accumulation might stimulate the ROS-scavenging system and proline biosynthesis via an integrative mechanism. This study demonstrates that the enhancement of GB biosynthesis in sweet potato is an effective and feasible approach to improve its tolerance to multiple abiotic stresses without causing phenotypic defects. This strategy for trait improvement in sweet potato not only stabilizes yield production in normal soils in unpredictable climates but also provides a novel germplasm for sweet potato production on marginal lands.

• Publication year

  2012

• Venue

  PLoS ONE

• Publication date

  2012-05-16

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology, Environmental Science

• Identifiers
  DOI 10.1371/journal.pone.0037344PMID 22615986PMCID 3353933
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• Enhanced glycine betaine accumulation was associated with better membrane integrity, stronger photosynthetic activity, lower ROS production, and activation of ROS-scavenging and proline-related responses.

  Confidence 0.92

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• SoBADH-expressing lines accumulated more glycine betaine and showed higher BADH activity under normal and stress conditions.

  Confidence 0.94

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• Overexpression of SoBADH in sweet potato increased tolerance to salt stress, oxidative stress, and low temperature.

  Confidence 0.98

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review

• abiotic stress tolerance

  trait

  The ability of the plant to withstand non-living stresses such as salt, oxidative, and low-temperature conditions.

  Aliases: stress tolerance

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• agrobacterium-mediated transformation

  method

  A plant genetic transformation method used to introduce the SoBADH gene into sweet potato.

  Aliases: Agrobacterium transformation

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• glycine betaine biosynthesis

  metabolic process

  The metabolic pathway that produces glycine betaine, an osmoprotectant in plants.

  Aliases: GB biosynthesis, glycine betaine production

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• proline accumulation

  metabolite process, physiological response

  The buildup of the amino acid proline in stressed plant tissues as a physiological response.

  Aliases: proline biosynthesis

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• reactive oxygen species scavenging

  molecular process

  Cellular detoxification of reactive oxygen species by antioxidant enzymes and related gene responses.

  Aliases: ROS scavenging

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• sobadh

  gene

  The chloroplastic betaine aldehyde dehydrogenase gene from Spinacia oleracea introduced into sweet potato for transgenic expression.

  Aliases: Spinach betaine aldehyde dehydrogenase, spinach BADH

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review
• transgenic sweet potato

  crop, plant line

  Sweet potato cultivar Sushu-2 genetically transformed with the introduced SoBADH construct.

  Aliases: transgenic sweet potato lines, Sushu-2 transformants

  박진우 (dztg5apj7m) extractionB (s683577b42) reviewKiller Whale (322360f1c1) reviewq (76h6bfydm6) review

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