T cell exhaustion during persistent viral infections.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Virology

• Publication date

  2015-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.virol.2014.12.033PMID 25620767PMCID PMC4424083
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses.

  2015cited by this paper
• SOCS3, a Major Regulator of Infection and Inflammation

  2014cited by this paper
• Bystander chronic infection negatively impacts development of CD8(+) T cell memory.

  2014cited by this paper
• Type I interferons protect T cells against NK cell attack mediated by the activating receptor NCR1.

  2014cited by this paper
• Type I interferon suppresses de novo virus-specific CD4 Th1 immunity during an established persistent viral infection

  2014cited by this paper
• Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection

  2014cited by this paper
• Reprogramming antitumor immunity.

  2014cited by this paper
• Epigenetic manipulation restores functions of defective CD8⁺ T cells from chronic viral infection.

  2014cited by this paper
• Type I interferon protects antiviral CD8+ T cells from NK cell cytotoxicity.

  2014cited by this paper
• Epigenetic Manipulation Restores Functions of Defective CD8+ T Cells From Chronic Viral Infection.

  2014cited by this paper
• Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1.

  2014influential reference
• Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection

  2014cited by this paper
• Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

  2014cited by this paper
• Too Much of a Good Thing? Tim-3 and TCR Signaling in T Cell Exhaustion

  2014cited by this paper
• Molecular and transcriptional basis of CD4⁺ T cell dysfunction during chronic infection.

  2014influential reference
• Expansion of Dysfunctional Tim-3–Expressing Effector Memory CD8+ T Cells during Simian Immunodeficiency Virus Infection in Rhesus Macaques

  2014cited by this paper
• Generation of rejuvenated antigen-specific T cells by reprogramming to pluripotency and redifferentiation.

  2013cited by this paper
• Strength of PD-1 signaling differentially affects T-cell effector functions

  2013cited by this paper
• Natural killer cells regulate diverse T cell responses.

  2013cited by this paper
• Molecular mechanisms of T cell co-stimulation and co-inhibition

  2013cited by this paper
• Macrophage and T Cell Produced IL-10 Promotes Viral Chronicity

  2013cited by this paper
• Circulating chemokine (C‐X‐C Motif) receptor 5+CD4+ T cells benefit hepatitis B e antigen seroconversion through IL‐21 in patients with chronic hepatitis B virus infection

  2013cited by this paper
• Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells

  2013cited by this paper
• The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses

  2013cited by this paper
• Cytokine-mediated programmed proliferation of virus-specific CD8(+) memory T cells.

  2013cited by this paper
• Galectin-9 and IL-21 Mediate Cross-regulation between Th17 and Treg Cells during Acute Hepatitis C

  2013cited by this paper
• The Depletion of NK Cells Prevents T Cell Exhaustion to Efficiently Control Disseminating Virus Infection

  2013cited by this paper
• IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection

  2013influential reference
• Therapeutic Depletion of Natural Killer Cells Controls Persistent Infection

  2013cited by this paper
• Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

  2013cited by this paper
• Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection

  2013cited by this paper
• HCV-specific interleukin-21+CD4+ T cells responses associated with viral control through the modulation of HCV-specific CD8+ T cells function in chronic hepatitis C patients

  2013cited by this paper
• Feline Immunodeficiency Virus Infection

  2013cited by this paper
• Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

  2013cited by this paper
• Memory T cell subsets, migration patterns, and tissue residence.

  2013cited by this paper
• Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

  2013cited by this paper
• NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections.

  2013cited by this paper
• T cells maintain an exhausted phenotype after antigen withdrawal and population reexpansion

  2013cited by this paper
• Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells.

  2013cited by this paper
• Reversal of chronic to resolved infection by IL‐10 blockade is LCMV strain dependent

  2013cited by this paper
• Anti-viral CD8 T cells and the cytokines that they love.

  2013cited by this paper
• PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.

  2013cited by this paper
• A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

  2013cited by this paper
• Tim-3-Expressing CD4+ and CD8+ T Cells in Human Tuberculosis (TB) Exhibit Polarized Effector Memory Phenotypes and Stronger Anti-TB Effector Functions

  2012cited by this paper
• Emergence of distinct multiarmed immunoregulatory antigen-presenting cells during persistent viral infection.

  2012cited by this paper
• Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection

  2012cited by this paper
• Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.

  2012cited by this paper
• The role of interleukin-2 during homeostasis and activation of the immune system

  2012cited by this paper
• B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1

  2012cited by this paper
• STATs shape the active enhancer landscape of T cell populations.

  2012cited by this paper
• Hepatitis c virus‐specific t‐cell‐derived transforming growth factor beta is associated with slow hepatic fibrogenesis

  2012cited by this paper
• IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis.

  2012cited by this paper
• Antigen amount dictates CD8+ T‐cell exhaustion during chronic viral infection irrespective of the type of antigen presenting cell

  2012cited by this paper
• Progenitor and Terminal Subsets of CD8+ T Cells Cooperate to Contain Chronic Viral Infection

  2012cited by this paper
• CD160 and PD-1 Co-Expression on HIV-Specific CD8 T Cells Defines a Subset with Advanced Dysfunction

  2012cited by this paper
• FoxP3+ regulatory CD4 T cells control the generation of functional CD8 memory

  2012cited by this paper
• Cutting Edge: Generation of Memory Precursors and Functional Memory CD8+ T Cells Depends on T Cell Factor-1 and Lymphoid Enhancer-Binding Factor-1

  2012cited by this paper
• Therapeutic Blockade of Transforming Growth Factor Beta Fails To Promote Clearance of a Persistent Viral Infection

  2012cited by this paper
• Transcriptional control of effector and memory CD8+ T cell differentiation

  2012cited by this paper
• From crucial to negligible: Functional CD8+ T‐cell responses and their dependence on CD4+ T‐cell help

  2012cited by this paper
• Inhibitory Receptors on Lymphocytes: Insights from Infections

  2012cited by this paper
• CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis

  2011cited by this paper
• Late Interleukin-6 Escalates T Follicular Helper Cell Responses and Controls a Chronic Viral Infection

  2011cited by this paper
• Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity

  2011cited by this paper
• Viral persistence redirects CD4 T cell differentiation toward T follicular helper cells

  2011cited by this paper
• Regulatory T Cells Selectively Control CD8+ T Cell Effector Pool Size via IL-2 Restriction

  2011cited by this paper
• T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection

  2011cited by this paper
• An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells.

  2011cited by this paper
• Dual Function of the NK Cell Receptor 2B4 (CD244) in the Regulation of HCV-Specific CD8+ T Cells

  2011influential reference
• Control of Toxoplasma reactivation by rescue of dysfunctional CD8+ T-cell response via PD-1–PDL-1 blockade

  2011cited by this paper
• 2B4+ CD8+ T cells play an inhibitory role against constrained HIV epitopes.

  2011cited by this paper
• Interleukin-21 administration to rhesus macaques chronically infected with simian immunodeficiency virus increases cytotoxic effector molecules in T cells and NK cells and enhances B cell function without increasing immune activation or viral replication.

  2011cited by this paper
• Phosphotyrosine-Dependent Coupling of Tim-3 to T-Cell Receptor Signaling Pathways

  2011cited by this paper
• Cytokines and the inception of CD8 T cell responses.

  2011cited by this paper
• Functional Capacity of Mycobacterium tuberculosis-Specific T Cell Responses in Humans Is Associated with Mycobacterial Load

  2011cited by this paper
• Immunotherapeutic effects of IL-7 during a chronic viral infection in mice.

  2011cited by this paper
• Antigen-Dependent and -Independent Mechanisms of T and B Cell Hyperactivation during Chronic HIV-1 Infection

  2011cited by this paper
• Chemokine receptor CXCR3 facilitates CD8+ T cell differentiation into short-lived effector cells leading to memory degeneration

  2011cited by this paper
• Suppressive CD8+ T Cells Arise in the Absence of CD4 Help and Compromise Control of Persistent Virus

  2011cited by this paper
• Type I IFN Substitutes for T Cell Help during Viral Infections

  2011cited by this paper
• T cell exhaustion

  2011cited by this paper
• Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection

  2011cited by this paper
• Exhausted CD8 T Cells Downregulate the IL-18 Receptor and Become Unresponsive to Inflammatory Cytokines and Bacterial Co-infections

  2011cited by this paper
• Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.

  2011cited by this paper
• Natural killer cells act as rheostats modulating antiviral T cells

  2011influential reference
• IL-21 and IL-6 Are Critical for Different Aspects of B Cell Immunity and Redundantly Induce Optimal Follicular Helper CD4 T Cell (Tfh) Differentiation

  2011cited by this paper
• IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.

  2011cited by this paper
• Pronounced Virus-Dependent Activation Drives Exhaustion but Sustains IFN-γ Transcript Levels

  2010cited by this paper
• Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.

  2010cited by this paper
• Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity.

  2010cited by this paper
• HIV-1-Specific Interleukin-21+ CD4+ T Cell Responses Contribute to Durable Viral Control through the Modulation of HIV-Specific CD8+ T Cell Function

  2010cited by this paper
• Integrative genomic analysis of HIV-specific CD8+ T cells reveals that PD-1 inhibits T cell function by upregulating BATF

  2010cited by this paper
• The regulation of IL-10 production by immune cells

  2010cited by this paper
• T‐cell exhaustion: characteristics, causes and conversion

  2010cited by this paper
• HIV-Specific IL-21 Producing CD4+ T Cells Are Induced in Acute and Chronic Progressive HIV Infection and Are Associated with Relative Viral Control

  2010cited by this paper
• Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1.

  2010cited by this paper
• Critical role for IL‐21 in both primary and memory anti‐viral CD8+ T‐cell responses

  2010cited by this paper
• Interleukin-21-Producing HIV-1-Specific CD8 T Cells Are Preferentially Seen in Elite Controllers

  2010cited by this paper
• Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

  2010cited by this paper
• Essential role of the Wnt pathway effector Tcf-1 for the establishment of functional CD8 T cell memory

  2010cited by this paper

• HIV status defines distinct immunological drivers of persistent portal hypertension after HCV cure in people with advanced cirrhosis

  2026cites this paper
• Immune Dysregulation in HIV-TB Co-Infection: Role of Cytokines and T Cell Biomarkers—A Narrative Review

  2026cites this paper
• Stepwise differentiation from precursor intermediates and distinct Th1 checkpoints promote CD4 Th1 cell differentiation during chronic viral infection.

  2026cites this paper
• World free HIV: the novel therapeutic approaches for eliminating latent HIV infection

  2026cites this paper
• Post-COVID impairment of memory T cell responses to community-acquired pathogens can be rectified by activating cellular metabolism

  2026cites this paper
• Molecular mimicry as a driver of T cell-mediated tumour immunity.

  2025cites this paper
• Blood memory CD8 T cell phenotypes in lung cancer patients predict immune checkpoint treatment responses

  2025cites this paper
• Influenza vaccines promote humoral and cellular immune responses: a randomized, double-blind, phase 3 trial

  2025cites this paper
• Sphingosine kinase 2 suppresses neutrophil responses to promote viral persistence while attenuating immune pathology

  2025cites this paper
• Beyond Canonical Immune Checkpoints: Overexpression of TNFRSF Members 4‐1BB and OX‐40 Marks T Cells Exhibiting Phenotypic Features of Exhaustion in Cervical Carcinoma

  2025cites this paper
• Mycobacterium tuberculosis Modulates the Expansion of Terminally Exhausted CD4+ and CD8+ T-Cells in Individuals with HIV-TB Co-Infection

  2025cites this paper
• T Cell Exhaustion in Allergic Diseases and Allergen Immunotherapy: A Novel Biomarker?

  2025cites this paper
• HIV, Inflammation, and Immunometabolism: A Model of the Inflammatory Theory of Disease

  2025cites this paper
• Vaccination against pathogens targeting cell-derived cryptic antigens.

  2025cites this paper
• The origin of autoimmune diseases: is there a role for ancestral HLA-II haplotypes in immune hyperactivity

  2025cites this paper
• Metabolic Reprogramming in Respiratory Viral Infections: A Focus on SARS-CoV-2, Influenza, and Respiratory Syncytial Virus

  2025cites this paper
• From infection to immune exhaustion: The Epstein-Barr virus and its contribution to Immunosenescence.

  2025cites this paper
• BKPyV-specific T-cell Exhaustion in Kidney Transplant Recipients: Targeting Inhibitory Receptors Improves Their Functionality.

  2025cites this paper
• Quantifying temporal differences in the induction of interferon-mediated signalling observed in a dengue virus 1 human infection model: insights from longitudinal proteome analysis

  2025cites this paper
• The immunomodulatory role of human cytomegalovirus in cancer in the era of checkpoint immunotherapy

  2025cites this paper
• T-cell dysfunction during blinatumomab therapy in pediatric acute lymphoblastic leukemia

  2025cites this paper
• The Role of Sustained Type I Interferon Secretion in Chronic HIV Pathogenicity: Implications for Viral Persistence, Immune Activation, and Immunometabolism

  2025cites this paper
• The role of TCF-1+CD8+ exhausted progenitors and TCF-1 in graft-versus-host responses

  2025cites this paper
• Tuberculosis Trends in the Post‐COVID‐19 Era: Is It Going to be a Global Concern?

  2025cites this paper
• Activated PI3 Kinase Delta Syndrome: Molecular Pathogenesis and Emerging Therapeutics

  2025cites this paper
• Immune regeneration: implications for cancer immunotherapy and beyond

  2025cites this paper
• Finetuning Type I Interferon Signaling to Enhance T Cell Immunity in HIV Infection

  2025cites this paper
• Association of leukocyte telomere length with anti-HBsAg antibody titer in Hepatitis-B recovered patients from the Pakistani population

  2025cites this paper
• HIV-1 controllers possess a unique CD8+ T cell activation phenotype and loss of control is associated with increased expression of exhaustion markers

  2025cites this paper
• Persistent Respiratory Symptoms Post-COVID-19 in a Non-Hodgkin Lymphoma Patient: A Case Report

  2025cites this paper
• Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses

  2025cites this paper
• Phenotyping Viral Reservoirs to Reveal HIV-1 Hiding Places

  2025cites this paper
• Neuroimmune-Endocrine Modulation of T-Cell Exhaustion in Central Nervous System Parasitic Diseases: Insights from Toxoplasmosis and Neurocysticercosis

  2025cites this paper
• Chronic Diseases and Influenza Vaccines

  2025cites this paper
• Effect of Immunoadsorption on clinical presentation and immune alterations in COVID-19-induced and/or aggravated ME/CFS.

  2025cites this paper
• Pathogens accelerate features of human aging: A review of molecular mechanisms.

  2025cites this paper
• Polarization of HIV-1- and CMV-Specific IL-17-Producing T Cells among People with HIV under Antiretroviral Therapy with Cannabis and/or Cocaine Usage

  2024cites this paper
• The Impact of Immune System Aging on Infectious Diseases

  2024cites this paper
• Immunological Signatures in Blood and Urine in 80 Individuals Hospitalized during the Initial Phase of COVID-19 Pandemic with Quantified Nicotine Exposure

  2024cites this paper
• Persistent HIV-1 transcription during ART: time to reassess its significance?

  2024cites this paper
• Chronic Viral Infection Compromises the Quality of Circulating Mucosal-Associated Invariant T Cells and Follicular T Helper Cells via Expression of Inhibitory Receptors.

  2024cites this paper
• IFN-γ, IL-17, IL-22+ CD4+ subset in patients with hepatitis C virus and correlation with clinical factor.

  2024cites this paper
• Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma

  2024cites this paper
• IFN-γ decreases PD-1 in T lymphocytes from convalescent COVID-19 patients via the AKT/GSK3β signaling pathway

  2024cites this paper
• Nef defect attenuates HIV viremia and immune dysregulation in the bone marrow-liver-thymus-spleen (BLTS) humanized mouse model.

  2024cites this paper
• Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responses

  2024cites this paper
• Mitigating non-genetic resistance to checkpoint inhibition based on multiple states of immune exhaustion

  2024cites this paper
• MitoTempo treatment as an approach to cure persistent viral infections?

  2024cites this paper
• Viral sepsis: diagnosis, clinical features, pathogenesis, and clinical considerations

  2024cites this paper
• The HCV-Melanoma Paradox: First Multi-Cohort and Molecular Net-Work Analysis Reveals Lower Incidence but Worse Outcomes—Integrating Clinical, Real-World, and In Silico Data

  2024cites this paper
• Effect of Immunoadsorption on clinical presentation and immune alterations in COVID-19-associated ME/CFS

  2024cites this paper
• Tuberculosis and T cells: Impact of T cell diversity in tuberculosis infection.

  2024cites this paper
• The influence of metabolic disorders on adaptive immunity

  2024cites this paper
• Applications of cell therapy in the treatment of virus-associated cancers

  2024influential citation
• Low-level HIV-1 viremia affects T-cell activation and senescence in long-term treated adults in the INSTI era

  2024cites this paper
• Wilson’s Disease—Crossroads of Genetics, Inflammation and Immunity/Autoimmunity: Clinical and Molecular Issues

  2024cites this paper
• Association between IL-6 rs1800795 and IL-1β rs 16944 gene polymorphisms with clinical severity of COVID-19 patients in Surakarta, Central Java, Indonesia

  2023cites this paper
• Identification of immunosuppressive signature subtypes and prognostic risk signatures in triple-negative breast cancer

  2023cites this paper
• Immunoregulatory functions of natural killer cells in avian influenza virus infection

  2023cites this paper
• A drug-delivery depot for epigenetic modulation and enhanced cancer immunotherapy.

  2023cites this paper
• T-Cell Exhaustion in HIV-1/Hepatitis C Virus Coinfection Is Reduced After Successful Treatment of Chronic Hepatitis C

  2023cites this paper
• Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses

  2023cites this paper
• Epstein–Barr virus-acquired immunodeficiency in myalgic encephalomyelitis—Is it present in long COVID?

  2023cites this paper
• Systems immunology of transcriptional responses to viral infection identifies conserved antiviral pathways across macaques and humans

  2023cites this paper
• Immune surveillance and humoral immune responses in kidney transplantation – A look back at T follicular helper cells

  2023cites this paper
• Long-term prognosis and overall mortality in patients with progressive multifocal leukoencephalopathy

  2023cites this paper
• Surveying the Metabolic and Dysfunctional Profiles of T Cells and NK Cells in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

  2023cites this paper
• T cells in health and disease

  2023cites this paper
• Single-cell multi-omics sequencing reveals the immunological disturbance underlying STAT3-V637M Hyper-IgE syndrome.

  2023cites this paper
• Overcoming immune checkpoint blockade resistance in solid tumors with intermittent ITK inhibition

  2023cites this paper
• Immunophenotypic analysis in participants with Kaposi sarcoma following pomalidomide administration

  2023cites this paper
• A Lower Dose of Infection Generates a Better Long-Term Immune Response against Toxoplasma gondii

  2023cites this paper
• PRRSV-1 induced lung lesion is associated with an imbalance between costimulatory and coinhibitory immune checkpoints

  2023cites this paper
• A Pathogenic Role of Non-Parenchymal Liver Cells in Alcohol-Associated Liver Disease of Infectious and Non-Infectious Origin

  2023cites this paper
• Inflammation and Epstein–Barr Virus at the Crossroads of Multiple Sclerosis and Post-Acute Sequelae of COVID-19 Infection

  2023influential citation
• Chronic viral infection compromises the quality of circulating mucosal-invariant T cells and follicular T helper cells via expression of both activating and inhibitory receptors

  2023cites this paper
• Features of the development of an adaptive antiviral immune response

  2023cites this paper
• An integrative analysis of the single-cell transcriptome identifies DUSP4 as an exhaustion-associated gene in tumor-infiltrating CD8+ T cells

  2023cites this paper
• Expression of viral CD45 ligand E3/49K on porcine cells reduces human anti-pig immune responses

  2023cites this paper
• Identification of cytokine-predominant immunosuppressive class and prognostic risk signatures in glioma

  2023cites this paper
• Death from human cytomegalovirus infection in a girl with congenital thymic dysplasia

  2022cites this paper
• Manipulation of diacylglycerol and ERK-mediated signaling differentially controls CD8+ T cell responses during chronic viral infection

  2022influential citation
• Cross-Reactive T Cell Response Exists in Chronic Lymphocytic Choriomeningitis Virus Infection upon Pichinde Virus Challenge

  2022cites this paper
• Age-Related Changes to the Immune System Exacerbate the Inflammatory Response to Pandemic H1N1 Infection

  2022cites this paper
• Th1 cytokine endotype discriminates and predicts severe complications in COVID-19

  2022cites this paper
• Association of baseline soluble immune checkpoints with the risk of relapse in PR3-ANCA vasculitis following induction of remission

  2022cites this paper
• Phenotypic characteristics of peripheral immune cells of Myalgic encephalomyelitis/chronic fatigue syndrome via transmission electron microscopy: A pilot study

  2022cites this paper
• CD4+ Cytotoxic T Cells Involved in the Development of EBV-Associated Diseases

  2022cites this paper
• CXCR5+CD8+ Follicular Cytotoxic T Cell Biology and Its Relationship with Diseases

  2022cites this paper
• Response to ‘Reduced Cell Surface Levels of C-C Chemokine Receptor 5 and Immunosuppression in Long Coronavirus Disease 2019 Syndrome’

  2022cites this paper
• Cellular Stress and Senescence Induction during Trypanosoma cruzi Infection

  2022cites this paper
• Age-Related Changes to the Immune System Exacerbate the Inflammatory Response to Pandemic H1N1 Infection

  2022cites this paper
• Association of treated and untreated chronic hepatitis C with the incidence of active tuberculosis disease: a population-based cohort study.

  2022cites this paper
• Modeling recapitulates the heterogeneous outcomes of SARS-CoV-2 infection and quantifies the differences in the innate immune and CD8 T-cell responses between patients experiencing mild and severe symptoms

  2022cites this paper
• Transcriptional Pattern Analysis of Virus-Specific CD8+ T Cells in Hepatitis C Infection: Increased Expression of TOX and Eomesodermin During and After Persistent Antigen Recognition

  2022cites this paper
• Role of the Complement System in the Modulation of T-Cell Responses in Chronic Chagas Disease

  2022cites this paper
• Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance

  2022cites this paper
• Antiretroviral therapy duration and immunometabolic state determine efficacy of ex vivo dendritic cell-based treatment restoring functional HIV-specific CD8+ T cells in people living with HIV

  2022cites this paper
• Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection

  2022cites this paper
• Post-Immune Antibodies in HIV-1 Infection in the Context of Vaccine Development: A Variety of Biological Functions and Catalytic Activities

  2022cites this paper