Melatonin in mice: rhythms, response to light, adrenergic stimulation, and metabolism.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Physiology. Regulatory Integrative and Comparative Physiology

• Publication date

  2002-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPREGU.00360.2001PMID 11792644
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Relationship of atypical melatonin rhythm with two circadian clock outputs in B6D2F(1) mice.

  2000cited by this paper
• Transcription factor dynamics and neuroendocrine signalling in the mouse pineal gland: a comparative analysis of melatonin‐deficient C57BL mice and melatonin‐proficient C3H mice

  2000cited by this paper
• Circadian rhythm of mt1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse 1

  2000cited by this paper
• Development and characterization of new flavivirus-resistant mouse strains bearing Flv(r)-like and Flv(mr) alleles from wild or wild-derived mice.

  1999cited by this paper
• Photoperiodic Control of the Rat Pineal Arylalkylamine-N-Acetyltransferase and Hydroxyindole-O-Methyltransferase Gene Expression and Its Effect on Melatonin Synthesis

  1999cited by this paper
• Enzymic synthesis of β-glucuronides of estradiol, ethynylestradiol and other phenolic substrates on a preparative scale employing UDP-glucuronyl transferase

  1998cited by this paper
• Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase.

  1998cited by this paper
• Daily Variations in Pineal Melatonin Concentrations in Inbred and Outbred Mice

  1998cited by this paper
• Creatinine is an appropriate reference for urinary sulphatoxymelatonin of laboratory animals and humans

  1997cited by this paper
• Serotonin-containing fibers in the suprachiasmatic hypothalamus attenuate light-induced phase delays in mice.

  1997cited by this paper
• Melatonin and Light Induce Phase Shifts of Circadian Activity Rhythms in the C3H/HeN Mouse

  1996cited by this paper
• HPLC validation of a circadian melatonin rhythm in the pineal gland of inbred mice

  1996cited by this paper
• Selective ablation of differentiated cells permits isolation of embryonic stem cell lines from murine embryos with a non–permissive genetic background

  1996cited by this paper
• A non‐invasive simple method for measurement of urinary excretion of melatonin in undisturbed mice

  1993cited by this paper
• Urinary 6-sulphatoxymelatonin excretory rhythms in laboratory rats: effects of photoperiod and light.

  1993cited by this paper
• Photic regulation of Fos‐like immunoreactivity in the suprachiasmatic nucleus of the mouse

  1992cited by this paper
• Diurnal variations of urinary 6‐sulphatoxymelatonin in male intact or ganglionectomized mink

  1992cited by this paper
• The influence of different light intensities on pineal melatonin content in the retinal degenerate C3H mouse and the normal CBA mouse.

  1990cited by this paper
• Treatment with forskolin for 8 hours during the day increases melatonin synthesis in the Syrian hamster pineal gland in organ culture: The long lag period is required for RNA synthesis

  1990cited by this paper
• Melatonin Content of the Pineal Gland in Different Mouse Strains

  1989cited by this paper
• A melatonin agonist and N-acetyl-N2-formyl-5-methoxykynurenamine accelerate the reentrainment of the melatonin rhythm following a phase advance of the light-dark cycle.

  1989cited by this paper
• Different Mechanisms of Phase Delays and Phase Advances of the Circadian Rhythm in Rat Pineal N-Acetyltransferase Activity

  1989cited by this paper
• Radioimmunoassay for 6-Sulphatoxymelatonin in Urine Using an Iodinated Tracer

  1988cited by this paper
• Day/night serotonin levels in the pineal gland of male BALB/c mice with melatonin deficiency.

  1988cited by this paper
• The Isolation, Purification, and Characterisation of the Principal Urinary Metabolites of Melatonin

  1987cited by this paper
• Gas chromatographic-mass spectrometric assay for 6-hydroxymelatonin sulfate and 6-hydroxymelatonin glucuronide in urine.

  1987cited by this paper
• Pineal indole metabolism in the mouse.

  1987cited by this paper
• The Pattern of Motor Activity, Light, and Melatonin Production in Syrian Hamsters

  1987cited by this paper
• Genetic control of melatonin synthesis in the pineal gland of the mouse.

  1986cited by this paper
• An Investigation of Demethylation in the Metabolism of Methoxytryptamine and Methoxytryptophol

  1985cited by this paper
• Melatonin is metabolized to N-acetyl serotonin and 6-hydroxymelatonin in man.

  1985cited by this paper
• Radioimmunoassay of 5-methoxy tryptophol in sheep plasma and pineal glands.

  1983cited by this paper
• Effect of melatonin feeding on serum prolactin and gonadotropin levels and the onset of seasonal estrous cyclicity in sheep.

  1982cited by this paper
• URINARY 6‐SULPHATOXY MELATONIN EXCRETION DURING THE HUMAN MENSTRUAL CYCLE

  1982cited by this paper
• Specific quantitation of urinary 6-hydroxymelatonin sulphate by gas chromatography mass spectrometry.

  1980cited by this paper
• The fate of melatonin in animals.

  1961cited by this paper

• Time‐of‐Day Impacts Uterine Circadian Rhythms and Response to Oxytocin: Comparison of Uterine Function in Melatonin‐Deficient C57BL/6 Versus Melatonin Proficient CBA/B6 Hybrid Mice

  2026cites this paper
• Melatonin Alleviates Circadian Rhythm Disruption‐Induced Enhanced Luteinizing Hormone Pulse Frequency and Ovarian Dysfunction

  2025cites this paper
• Immune regulation of host energy metabolism and periodicity of malaria parasites

  2025cites this paper
• The specificities, influencing factors, and medical implications of bone circadian rhythms

  2024cites this paper
• Advances in the study of the influence of photoreceptors on the development of myopia.

  2024cites this paper
• The Discovery of Gut Microbial Metabolites as Modulators of Host Susceptibility to Acetaminophen-Induced Hepatotoxicity

  2024cites this paper
• Homeobox gene‐encoded transcription factors in development and mature circadian function of the rodent pineal gland

  2024cites this paper
• Digital automation of transdermal drug delivery with high spatiotemporal resolution

  2024cites this paper
• The cognitive impact of light: illuminating ipRGC circuit mechanisms

  2024cites this paper
• Disaggregating the effects of daytime and nighttime light exposures on obesity, overweight, prostate and breast cancer morbidity worldwide

  2023cites this paper
• Sleep and the sleep electroencephalogram in C57BL/6 and C3H/HeN mice

  2023cites this paper
• Pars Distalis and Pars Tuberalis Thyroid-Stimulating Hormones and Their Roles in Macro-Thyroid-Stimulating Hormone Formation

  2023cites this paper
• First preclinical evaluation of [225Ac]Ac-DOTA-JR11 and comparison with [177Lu]Lu-DOTA-JR11, alpha versus beta radionuclide therapy of NETs

  2023cites this paper
• Vivarium Lighting as an Important Extrinsic Factor Influencing Animal-based Research.

  2023cites this paper
• Hypotensive effects of melatonin in rats: Focus on the model, measurement, application, and main mechanisms

  2022cites this paper
• Keep Your Mask On: The Benefits of Masking for Behavior and the Contributions of Aging and Disease on Dysfunctional Masking Pathways

  2022cites this paper
• The circadian system in cystic fibrosis mice is regulated by histone deacetylase 6

  2022cites this paper
• Strain and Age Dependent Entrainable Range of Circadian Behavior in C57BL/6 and BALB/c Mice.

  2022cites this paper
• Bimodal serotonin synthesis in the diurnal rodent, Arvicanthis ansorgei

  2022cites this paper
• Melatonin levels in the Alzheimer’s disease continuum: a systematic review

  2021cites this paper
• Obese Neotomodon alstoni mice exhibit sexual dimorphism in the daily profile of circulating melatonin and clock proteins PER1 and BMAL1 in the hypothalamus and peripheral oscillators

  2021cites this paper
• Exploring the effects of large-area dorsal skin irradiation on locomotor activity and plasm melatonin level in C3H/He mice

  2021cites this paper
• Interconnections between circadian clocks and metabolism.

  2021cites this paper
• Tubulin Polymerization Promoting Protein Affects the Circadian Timing System in C57Bl/6 Mice

  2021cites this paper
• Can we believe results obtained from plasma melatonin ELISA kits?

  2021cites this paper
• Major oscillations in spontaneous home-cage activity in C57BL/6 mice housed under constant conditions

  2021cites this paper
• Interconnections between circadian clocks and metabolism

  2021cites this paper
• Role of Circadian Rhythm and Impact of Circadian Rhythm Disturbance on the Metabolism and Disease

  2021cites this paper
• Desynchronized circadian clock and exposures to xenobiotics are associated with differentiated disease phenotypes

  2021cites this paper
• Dim light in the evening causes coordinated realignment of circadian rhythms, sleep, and short-term memory

  2021cites this paper
• ANTIGENOTOXIC EFFECTS OF MELATONIN AGAINST CHROMOSOME DAMAGE INDUCED BY 7,12- DYMETHYLBENZ(a)ANTHRACENE

  2020cites this paper
• Major oscillations in spontaneous home-cage activity with an infraradian periodicity in C57Bl/6 mice housed under constant conditions

  2020cites this paper
• Circadian Regulation of Blood Pressure: of Mice and Men

  2020cites this paper
• Shiftwork and Light at Night Negatively Impact Molecular and Endocrine Timekeeping in the Female Reproductive Axis in Humans and Rodents

  2020cites this paper
• Measuring melatonin by immunoassay

  2020cites this paper
• Home-cage hypoactivity in mouse genetic models of autism spectrum disorder.

  2019cites this paper
• Light Pollution, Circadian Photoreception, and Melatonin in Vertebrates

  2019influential citation
• Melatonin-Deficient Balb/c Mice and Their Use in Cancer Research

  2019cites this paper
• Influence of Daytime LED Light Exposure on Circadian Regulatory Dynamics of Metabolism and Physiology in Mice.

  2019cites this paper
• Smith-Magenis Syndrome: Molecular Basis of a Genetic-Driven Melatonin Circadian Secretion Disorder

  2019cites this paper
• Melatonin research in mice: a review

  2019influential citation
• Mammary tumors compromise time-of-day differences in hypothalamic gene expression and circadian behavior and physiology in mice.

  2019cites this paper
• Dosage time affects alkylating agents induced micronuclei in mouse peripheral blood reticulocytes through the function of erythropoietin.

  2019cites this paper
• A critical review of melatonin assays: Past and present

  2019cites this paper
• Effects of Light at Night on Laboratory Animals and Research Outcomes

  2018cites this paper
• MICOP: Maximal information coefficient-based oscillation prediction to detect biological rhythms in proteomics data

  2018cites this paper
• A congenic line of the C57BL/6J mouse strain that is proficient in melatonin synthesis

  2018cites this paper
• Effect of Daytime Blue-enriched LED Light on the Nighttime Circadian Melatonin Inhibition of Hepatoma 7288CTC Warburg Effect and Progression.

  2018cites this paper
• Melatonin promotes sleep in mice by inhibiting orexin neurons in the perifornical lateral hypothalamus

  2018cites this paper
• A Crosstalk between Melatonin and Taste-Receptors’ Signaling Tunes Quinine-Induced Gut Hormone Secretion in Mice

  2018cites this paper
• Circadian Regulation of Bone

  2017cites this paper
• Connexin36 localization to pinealocytes in the pineal gland of mouse and rat

  2017influential citation
• Melatonin inhibits neuronal dysfunction‐associated with neuroinflammation by atopic psychological stress in NC/Nga atopic‐like mouse models

  2017cites this paper
• Timing of host feeding drives rhythms in parasite replication

  2017cites this paper
• Maternal and Early-Life Circadian Disruption Have Long-Lasting Negative Consequences on Offspring Development and Adult Behavior in Mice

  2017cites this paper
• Chapter 39 – Circadian Dysregulation in Mental and Physical Health

  2017cites this paper
• Artificial Light at Night and Obesity: Does the Spread of Wireless Information and Communication Technology Play a Role?

  2016cites this paper
• Does artificial light-at-night exposure contribute to the worldwide obesity pandemic?

  2016cites this paper
• Effects of Colored Enrichment Devices on Circadian Metabolism and Physiology in Male Sprague-Dawley Rats.

  2016cites this paper
• Effects of Daytime Exposure to Light from Blue-Enriched Light-Emitting Diodes on the Nighttime Melatonin Amplitude and Circadian Regulation of Rodent Metabolism and Physiology.

  2016cites this paper
• Circadian rhythms in the auditory system

  2016cites this paper
• Metabolites as Clock Hands: Estimation of Internal Body Time Using Blood Metabolomics

  2016cites this paper
• From Association to Function: MTNR1B

  2016cites this paper
• Melatonin Induces Antidepressant-Like Behavior by Promotion of Adult Hippocampal Neurogenesis

  2016cites this paper
• Activity and circadian rhythm influence synaptic Shank3 protein levels in mice

  2016cites this paper
• Plasticity of circadian clocks and consequences for metabolism

  2015cites this paper
• Daytime Blue Light Enhances the Nighttime Circadian Melatonin Inhibition of Human Prostate Cancer Growth.

  2015cites this paper
• The influence of red light exposure at night on circadian metabolism and physiology in Sprague-Dawley rats.

  2015cites this paper
• Photoperiodic modulation of voluntary ethanol intake in C57BL/6 mice.

  2015cites this paper
• Adult hippocampal neurogenesis in natural populations of mammals.

  2015cites this paper
• Light at night, melatonin and breast cancer

  2014cites this paper
• Aus der Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie der Medizinischen Fakultät der Universität des

  2014cites this paper
• Effects of chronic jet lag on the central and peripheral circadian clocks in CBA/N mice

  2014cites this paper
• Impact of melatonin receptor deletion on intracellular signaling in spleen cells of mice after polymicrobial sepsis

  2014cites this paper
• Role of MT1/ MT2 Melatonin Membrane Receptors in Mediating the Neuroprotective Effects of Melatonin in Alzheimer's Disease

  2014cites this paper
• Diurnal variation in physiological, psychological and immune responses to running 10 km time trials performed in hot and cold environments

  2014cites this paper
• Genetic deletion of MT₁/MT₂ melatonin receptors enhances murine cognitive and motor performance.

  2014cites this paper
• Genetic deletion of MT1 melatonin receptors alters spontaneous behavioral rhythms in male and female C57BL/6 mice.

  2014influential citation
• Authors' Reply

  2014influential citation
• Nocturnal Light Exposure Alters Hepatic Pai-1 Expression by Stimulating the Adrenal Pathway in C3H Mice

  2014cites this paper
• Minireview: Toward the establishment of a link between melatonin and glucose homeostasis: association of melatonin MT2 receptor variants with type 2 diabetes.

  2013cites this paper
• Melatonin Receptor MT1 is Expressed in Mouse Skin and In vitro Melatonin Treatment Enhances Whisker Growth

  2013cites this paper
• Establishment of TSH β real-time monitoring system in mammalian photoperiodism

  2013influential citation
• Melatonin acts through MT1/MT2 receptors to activate hypothalamic Akt and suppress hepatic gluconeogenesis in rats.

  2013cites this paper
• Aryl hydrocarbon receptor activation attenuates Per1 gene induction and influences circadian clock resetting.

  2013cites this paper
• Physiological consequences of circadian disruption by nighttime light exposure

  2013cites this paper
• Effect of spectral transmittance through red-tinted rodent cages on circadian metabolism and physiology in nude rats.

  2013cites this paper
• Endocrine rhythms in the brown bear (Ursus arctos): Evidence supporting selection for decreased pineal gland size

  2013cites this paper
• Effects of spectral transmittance through standard laboratory cages on circadian metabolism and physiology in nude rats.

  2013cites this paper
• Molecular pharmacology of the mouse melatonin receptors MT₁ and MT₂.

  2012cites this paper
• Human blood metabolite timetable indicates internal body time

  2012cites this paper
• PHYSIOLOGICAL INTEGRATION OF SEASONAL AND DAILY CUES IN THE NORTH AMERICAN

  2012cites this paper
• Light interference as a possible stressor altering HSP70 and its gene expression levels in brain and hepatic tissues of golden spiny mice

  2012cites this paper
• Effects on bone by the light/dark cycle and chronic treatment with melatonin and/or hormone replacement therapy in intact female mice

  2012influential citation
• Biological Rhythms of the Mouse

  2012cites this paper
• Adipokines and Adipocyte Function in Clock Mutant Mice That Retain Melatonin Rhythmicity

  2012cites this paper
• Novel Insights into the Downstream Pathways and Targets Controlled by Transcription Factors CREM in the Testis

  2012cites this paper
• Melatonin Time Line: From Discovery to Therapy

  2011cites this paper
• Eliminating animal facility light-at-night contamination and its effect on circadian regulation of rodent physiology, tumor growth, and metabolism: a challenge in the relocation of a cancer research laboratory.

  2011cites this paper
• Enantioselective micro-2D-HPLC determination of aspartic acid in the pineal glands of rodents with various melatonin contents.

  2011cites this paper