Identification of a potent sodium hydrogen exchanger isoform 1 (NHE1) inhibitor with a suitable profile for chronic dosing and demonstrated cardioprotective effects in a preclinical model of myocardial infarction in the rat.

J. Huber,Jörg Bentzien,S. Boyer,J. Burke,S. De Lombaert,C. Eickmeier,Xin Guo,J. Haist,E. Hickey,P. Kaplita,M. Karmazyn,R. Kemper,C. Kennedy,T. Kirrane,J. Madwed,E. Mainolfi,Nelamangara Nagaraja,Fariba Soleymanzadeh,A. Swinamer,A. B. Eldrup

Published 2012 in Journal of Medicinal Chemistry

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