The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects*

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Critical Care Medicine

• Publication date

  2006-01-30

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/01.CCM.0000198107.61493.5APMID 16424721
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Early goal-directed therapy in the treatment of severe sepsis and septic shock.

  2018cited by this paper
• Microvascular alterations in patients with acute severe heart failure and cardiogenic shock.

  2004cited by this paper
• Persistent microcirculatory alterations are associated with organ failure and death in patients with septic shock*

  2004cited by this paper
• Lactic acidosis

  2003cited by this paper
• Nitroglycerin for septic shock.

  2003cited by this paper
• Bench-to-bedside review: Microvascular dysfunction in sepsis –hemodynamics, oxygen transport, and nitric oxide

  2003cited by this paper
• Effect of vasopressin on sublingual microcirculation in a patient with distributive shock

  2003cited by this paper
• Endothelin receptor antagonist bosentan improves microcirculatory blood flow in splanchnic organs in septic shock

  2003cited by this paper
• 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference

  2003cited by this paper
• Optimal Adrenergic Support in Septic Shock Due to Peritonitis

  2003cited by this paper
• Microvascular blood flow is altered in patients with sepsis.

  2002cited by this paper
• Nitroglycerin in septic shock after intravascular volume resuscitation.

  2002influential reference
• Opening the microcirculation: can vasodilators be useful in sepsis?

  2002cited by this paper
• Effects of dobutamine and dopexamine on hepatic micro- and macrocirculation during experimental endotoxemia: An intravital microscopic study in the rat

  2001influential reference
• Aminoethyl-isothiourea inhibits the increase in plasma endothelin-1 caused by serogroup A streptococci and prolongs survival in rat peritoneal sepsis.

  2001cited by this paper
• Effects of dobutamine on hepato-splanchnic hemodynamics in an experimental model of hyperdynamic endotoxic shock.

  2001cited by this paper
• Assessment of the microcirculatory flow in patients in the intensive care unit

  2001cited by this paper
• Microcirculation in intestinal villi: a comparison between hemorrhagic and endotoxin shock.

  2001cited by this paper
• Early Goal-Directed Therapy in the Treatment of Severe Sepsis and Septic Shock

  2001cited by this paper
• Effects of nitric oxide in septic shock.

  2000cited by this paper
• Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure.

  2000cited by this paper
• Dopexamine attenuates flow motion in ileal mucosal arterioles in normotensive sepsis.

  1999cited by this paper
• Effects of epinephrine, norepinephrine, or the combination of norepinephrine and dobutamine on gastric mucosa in septic shock.

  1999cited by this paper
• Does hepato-splanchnic VO2/DO2 dependency exist in critically ill septic patients?

  1998cited by this paper
• Effects of a Dobutamine‐induced Increase in Splanchnic Blood Flow on Hepatic Metabolic Activity in Patients with Septic Shock

  1997cited by this paper
• Dobutamine maintains intestinal villus blood flow during normotensive endotoxemia: an intravital microscopic study in the rat.

  1997cited by this paper
• The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure

  1996cited by this paper
• Dopexamine maintains intestinal villus blood flow during endotoxemia in rats.

  1996cited by this paper
• Regional effects of dobutamine in endotoxic shock.

  1996cited by this paper
• Effects of iloprost, a stable prostacyclin analog, and its combination with NW-nitro-L-arginine on early events following lipopolysaccharide injection: observations in the hamster cheek pouch microcirculation.

  1995cited by this paper
• Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia.

  1994cited by this paper
• High-energy phosphates in heart, liver, kidney, and skeletal muscle of endotoxemic rats.

  1994cited by this paper
• In vivo effects of Escherichia coli endotoxemia on diaphragmatic microcirculation in rats.

  1992cited by this paper
• The assessment of the microcirculatory effects of dobutamine using mercury in silastic strain gauge plethysmography in man.

  1991cited by this paper
• Lack of a relationship between induced changes in oxygen consumption and changes in lactate levels.

  1991cited by this paper
• The accuracy of creatinine clearance with and without urine collection as a measure of glomerular filtration rate.

  1991cited by this paper
• APACHE II: A severity of disease classification system

  1985cited by this paper
• Lactic acidosis.

  1971cited by this paper

• Diffuse large B-cell lymphoma combined with hyperlactatemia presents high mortality: case report and literature review.

  2026cites this paper
• Vasoactive Medications and the Microcirculation in Septic Shock: A Scoping Review.

  2026cites this paper
• Microcirculatory alterations in critical care: A narrative review.

  2026cites this paper
• Effects of adjunctive dobutamine on outcomes among patients with septic shock: a propensity score matching analysis

  2025cites this paper
• Sepsis-Induced Cardiomyopathy and Cardiac Arrhythmias: Pathophysiology and Implications for Novel Therapeutic Approaches

  2025cites this paper
• Early dobutamine response to delayed cerebral ischemia affected by vasospasm after subarachnoid hemorrhage: Serial cerebral blood flow analyses using O-15-water positron-emission tomography – A report of two cases

  2025cites this paper
• Mechanisms of sepsis-induced acute liver injury: a comprehensive review

  2025cites this paper
• An increase in skin blood flow after red blood cell transfusion is associated with an improvement in organ function in critically ill patients.

  2025cites this paper
• Minimally-Invasive Imaging of Sublingual Vessels—A New Method to Study Microvascular Changes in Mice

  2025cites this paper
• Rethinking adjunctive dobutamine in septic shock: time to individualize, not generalize

  2025cites this paper
• Advancing Microcirculatory Therapies in Pediatric Sepsis: Current Opportunities and Future Directions.

  2025cites this paper
• Management of Vasodilatory Shock: A Concise Review.

  2025cites this paper
• Microcirculatory Dysfunction in Sepsis.

  2025cites this paper
• Application of microcirculatory indicators in predicting the prognosis of patients with septic shock

  2024cites this paper
• Microcirculation, endothelium and glycocalyx changes associated with the use of milrinone in children with septic shock

  2024cites this paper
• Early management of adult sepsis and septic shock: Korean clinical practice guidelines

  2024cites this paper
• Nitroglycerin challenge identifies microcirculatory target for improved resuscitation in patients with circulatory shock

  2024cites this paper
• Incoherence between systemic and skin tissue response to transfusion in volume-resuscitated patients withoutacute bleeding

  2024cites this paper
• Hacia la personalización de la reanimación del paciente con shock séptico: fundamentos del ensayo ANDROMEDA-SHOCK-2

  2024cites this paper
• Prognostic value of serum lactate level for mortality in patients with acute kidney injury

  2024cites this paper
• The Effects of Dobutamine in Septic Shock: An Updated Narrative Review of Clinical and Experimental Studies

  2024cites this paper
• Lactate dynamics in paediatric patients with severe sepsis: insights from a prospective cohort study

  2024cites this paper
• Towards the personalization of septic shock resuscitation: the fundamentals of ANDROMEDA-SHOCK-2 trial.

  2024cites this paper
• The Prognostic Value of the Muscle Regional Oxygen Saturation Index in Patients with Acute Respiratory Distress Syndrome

  2024cites this paper
• Clinical evaluation of peripheral tissue perfusion as a predictor of mortality in sepsis and septic shock in the intensive care unit: Systematic review and meta-analysis.

  2023cites this paper
• Microcirculation and Mitochondria: The Critical Unit

  2023cites this paper
• The microcirculation in perioperative medicine: a narrative review.

  2023cites this paper
• Microcirculation-guided resuscitation in sepsis: the next frontier?

  2023cites this paper
• Transfusion increased skin blood flow when initially low in volume-resuscitated patients without acute bleeding

  2023cites this paper
• Circulatory shock in adults in emergency department

  2023cites this paper
• Intraoperative intravenous infusion of lidocaine increases total and small vessel densities of sublingual microcirculation: a randomized prospective pilot study

  2023cites this paper
• Devices for assessing microcirculation

  2023cites this paper
• Use of CO2-Derived Variables in Cardiac Intensive Care Unit: Pathophysiology and Clinical Implications

  2023cites this paper
• Impact of Vasodilator Administration on Survival in Patients with Sepsis: A Systematic Review and Meta-Analysis.

  2023cites this paper
• Modeling the relationship between arterial blood pressure and sublingual microcirculatory blood flow assessed by Sidestream Dark Field videomicroscopy: An experimental study in anesthetized piglets.

  2023cites this paper
• Hemodynamic effects and tolerance of dobutamine for myocardial dysfunction during septic shock: An observational multicenter prospective echocardiographic study

  2022cites this paper
• Lactic Acidosis Related to Pharmacotherapy and Human Diseases

  2022cites this paper
• [Vasoactive drugs in the treatment of septic shock].

  2022cites this paper
• New Hydrogels Based on Agarose/Phytagel and Peptides.

  2022cites this paper
• Endothelial Activation and Microcirculatory Disorders in Sepsis

  2022cites this paper
• A novel non-invasive method of measuring microcirculatory perfusion and blood velocity in infants: a pilot study

  2022cites this paper
• Advances in Microcirculatory Assessment: A Game Changer in Sepsis Management or the Latest Fad?

  2022cites this paper
• Venoarterial extracorporeal membrane oxygenation flow or dobutamine to improve microcirculation during ECMO for refractory cardiogenic shock.

  2022cites this paper
• Microcirculation during surgery

  2022cites this paper
• Novelties in the evaluation of microcirculation in septic shock

  2022cites this paper
• Unfractionated Heparin Improves the Intestinal Microcirculation in a Canine Septic Shock Model

  2021cites this paper
• Echocardiography of the Ventilated Patient

  2021cites this paper
• Monitoring skin blood flow to rapidly identify alterations in tissue perfusion during fluid removal using continuous veno-venous hemofiltration in patients with circulatory shock

  2021cites this paper
• Levosimendan Ameliorates Post-resuscitation Acute Intestinal Microcirculation Dysfunction Partly Independent of its Effects on Systemic Circulation: A Pilot Study on Cardiac Arrest in a Rat Model

  2021cites this paper
• Addition of admission lactate levels to Baux score improves mortality prediction in severe burns

  2021cites this paper
• Serum lactate level predicts 6-months mortality in patients with hepatitis B virus-related decompensated cirrhosis: a retrospective study

  2021cites this paper
• Biochemical markers for clinical monitoring of tissue perfusion

  2021cites this paper
• Hemodynamic Management in the Neurocritical Patient

  2021cites this paper
• Septic shock: a microcirculation disease

  2021influential citation
• Lactate Clearance Is Associated With Improved Survival in Cardiogenic Shock: A Systematic Review and Meta-Analysis of Prognostic Factor Studies.

  2021cites this paper
• Current practice and evolving concepts in septic shock resuscitation

  2021cites this paper
• Die Rolle der Mikrozirkulation in der Entstehung des Organversagens

  2021cites this paper
• Association between dose of catecholamines and markers of organ injury early after out-of-hospital cardiac arrest

  2021cites this paper
• Is the Sympathetic System Detrimental in the Setting of Septic Shock, with Antihypertensive Agents as a Counterintuitive Approach? A Clinical Proposition

  2021cites this paper
• Lactate: Where Are We Now?

  2020cites this paper
• Monitoring Microcirculation: Utility and Barriers – A Point-of-View Review

  2020influential citation
• Hyperlactatémie en réanimation

  2020cites this paper
• Monitoring peripheral perfusion in sepsis associated acute kidney injury: Analysis of mortality

  2020cites this paper
• AUDINIŲ PERFUZIJOS VERTINIMAS ŠOKO METU

  2020cites this paper
• Heart Dysfunction in Sepsis.

  2020cites this paper
• Mean core to peripheral temperature difference and mean lactate levels in first 6 hours of hospitalisation as two indicators of prognosis: an observational cohort study

  2020cites this paper
• Microcirculatory Blood Flow as a New Tool for Perioperative Fluid Management

  2020cites this paper
• VHRM_A_242635 577..589

  2020influential citation
• Inodilators in septic shock: should these be used?

  2020influential citation
• Assessment of sublingual microcirculation in critically ill patients: consensus and debate

  2020cites this paper
• Bedside prediction of intradialytic hemodynamic instability in critically ill patients: the SOCRATE study

  2020cites this paper
• Lymphatic flow modulation as adjunct therapy for septic shock.

  2020cites this paper
• Automated quantification of tissue red blood cell perfusion as a new resuscitation target.

  2020cites this paper
• Cardio-centric hemodynamic management improves spinal cord oxygenation and mitigates hemorrhage in acute spinal cord injury

  2020cites this paper
• Evaluation of the Microcirculation in Critically Ill Patients

  2020cites this paper
• Optimal target in septic shock resuscitation

  2020cites this paper
• Sweat the small stuff: The human microvasculature and heart disease

  2020cites this paper
• Microcirculation vs. Mitochondria—What to Target?

  2020cites this paper
• Microvascular Dysfunction in the Critically Ill.

  2020cites this paper
• Microcirculatory Dysfunction in Acute Heart Failure

  2019cites this paper
• Role of serial lactate measurement to predict 28-day mortality in patients undergoing emergency laparotomy for perforation peritonitis: prospective observational study

  2019cites this paper
• Assessment of the peripheral microcirculation in patients with and without shock: a pilot study on different methods

  2019cites this paper
• Alterations of retinal vessels in patients with sepsis

  2019cites this paper
• Microcirculation: Physiology, Pathophysiology, and Clinical Application

  2019cites this paper
• Recruitment of non‐perfused sublingual capillaries increases microcirculatory oxygen extraction capacity throughout ascent to 7126 m

  2019cites this paper
• Dissociation between macro- and microvascular parameters in the early phase of hemorrhagic shock.

  2019cites this paper
• Prognostic values of the Berlin definition criteria, blood lactate level, and fibroproliferative changes on high-resolution computed tomography in ARDS patients

  2019cites this paper
• Challenges in the management of septic shock: a narrative review

  2019cites this paper
• Changes in the sublingual microcirculation following aortic surgery under balanced or total intravenous anaesthesia: a prospective observational study

  2019cites this paper
• Is microcirculatory assessment ready for regular use in clinical practice?

  2019cites this paper
• Influence of systemic hemodynamics on microcirculation during sepsis.

  2019cites this paper
• Minimizing catecholamines and optimizing perfusion

  2019cites this paper
• Recruiting the microcirculation in septic shock

  2019cites this paper
• Effects of Rapid and Ultra-Rapid Fluid Resuscitation Guided by Blood Lactate Clearance Rate in Diarrheic Calves

  2019cites this paper
• Consensus document ANMCO/FADOI/SIAARTI/SIC/SIMG/SIMI/SIMEU: The clinical-diagnostic and therapeutic pathway of patients with acute heart failure in the Emergency Department

  2019cites this paper
• Hyperlactatemia and Lactic Acidosis

  2019cites this paper
• Manipulating the Microcirculation in Sepsis - the Impact of Vasoactive Medications on Microcirculatory Blood Flow: A Systematic Review.

  2019influential citation
• Assessment of the Microcirculation

  2019cites this paper
• From a pressure-guided to a perfusion-centered resuscitation strategy in septic shock: Critical literature review and illustrative case.

  2019cites this paper
• Perioperative Haemodynamic Optimisation

  2019cites this paper