Formation of benzo(a)pyrene/DNA adducts and their relationship to tumor initiation in mouse epidermis.

No abstract is available for this paper.

• Publication year

  1983

• Venue

  Cancer Research

• Publication date

  1983-03-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  PMID 6297716
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vivo formation of benzo (a) pyrene diol epoxide‐deoxyadenosine adducts in the skin of mice susceptible to benzo (a) pyrene‐induced carcinogenesis

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  1980cited by this paper
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• Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice.

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• Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

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• Binding of benzo[a]pyrene 7,8-diol-9,10-epoxides to DNA, RNA, and protein of mouse skin occurs with high stereoselectivity.

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  1976cited by this paper
• Exceptional mutagenicity of a benzo[a]pyrene diol epoxide in cultured mammalian cells

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• The involvement of a diol‐epoxide in the metabolic activation of benzo(a)pyrene in human bronchial mucosa and in mouse skin

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• Isolation of the hydrocarbon-deoxyribonucleoside products from the DNA of mouse embryo cells treated in culture with 7-methylbenz(a)anthracene-3H.

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  1967cited by this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1996cites this paper
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  1995cites this paper
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  1990cites this paper
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  1990cites this paper
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  1990cites this paper
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  1990influential citation
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