Regulation of DNA replication during development

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Development

• Publication date

  2012-02-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.061838PMID 22223677PMCID PMC3252349
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Developmental control of gene copy number by repression of replication initiation and fork progression.

  2012cited by this paper
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  2011cited by this paper
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  2011cited by this paper
• Genome-wide depletion of replication initiation events in highly transcribed regions.

  2011cited by this paper
• CDK prevents Mcm2-7 helicase loading by inhibiting Cdt1 interaction with Orc6.

  2011cited by this paper
• Defining the replication program through the chromatin landscape

  2011cited by this paper
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  2011influential reference
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  2011influential reference
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  2011cited by this paper
• Bubble-chip analysis of human origin distributions demonstrates on a genomic scale significant clustering into zones and significant association with transcription.

  2011cited by this paper
• Geminin Escapes Degradation in G1 of Mouse Pluripotent Cells and Mediates the Expression of Oct4, Sox2, and Nanog

  2011cited by this paper
• Mutations in origin recognition complex gene ORC4 cause Meier-Gorlin syndrome

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• Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome

  2011influential reference
• Integrative analysis of gene amplification in Drosophila follicle cells: parameters of origin activation and repression.

  2011influential reference
• CDK prevents Mcm 2 – 7 helicase loading by inhibiting Cdt 1 interaction with Orc 6

  2011cited by this paper
• Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

  2011cited by this paper
• Regulation of DNA replication through Sld3-Dpb11 interaction is conserved from yeast to humans.

  2011cited by this paper
• UvA-DARE ( Digital Academic Repository ) Reading the maps : Organization and function of chromatin types in Drosophila Braunschweig

  2010cited by this paper
• Genomic Study of Replication Initiation in Human Chromosomes Reveals the Influence of Transcription Regulation and Chromatin Structure on Origin Selection

  2010influential reference
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010cited by this paper
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  2010influential reference
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  2010cited by this paper
• Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading.

  2010influential reference
• Evaluating genome-scale approaches to eukaryotic DNA replication

  2010cited by this paper
• Mec1 is one of multiple kinases that prime the Mcm2-7 helicase for phosphorylation by Cdc7.

  2010cited by this paper
• Mec 1 Is One of Multiple Kinases that Prime the Mcm 2-7 Helicase for Phosphorylation by Cdc 7

  2010cited by this paper
• Activation of the MCM2-7 helicase by association with Cdc45 and GINS proteins.

  2010cited by this paper
• Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification

  2010cited by this paper
• Single-Molecule Analysis Reveals Changes in the DNA Replication Program for the POU5F1 Locus upon Human Embryonic Stem Cell Differentiation

  2010cited by this paper
• Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?

  2009cited by this paper
• Predictable dynamic program of timing of DNA replication in human cells.

  2009cited by this paper
• Orc1 Controls Centriole and Centrosome Copy Number in Human Cells

  2009cited by this paper
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  2009cited by this paper
• The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

  2009cited by this paper
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  2009cited by this paper
• Domain-wide regulation of DNA replication timing during mammalian development

  2009cited by this paper
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  2009cited by this paper
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  2009cited by this paper
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  2009influential reference
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  2009influential reference
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  2009cited by this paper
• Genome-wide studies highlight indirect links between human replication origins and gene regulation

  2008influential reference
• Global organization of replication time zones of the mouse genome.

  2008cited by this paper
• Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

  2008influential reference
• Endocycling cells do not apoptose in response to DNA rereplication genotoxic stress.

  2008cited by this paper
• CDK-dependent phosphorylation of Sld2 and Sld3 initiates DNA replication in budding yeast

  2007cited by this paper
• Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast

  2007cited by this paper
• Developmentally regulated histone modifications in Drosophila follicle cells: initiation of gene amplification is associated with histone H3 and H4 hyperacetylation and H1 phosphorylation

  2007cited by this paper
• Strength in numbers: preventing rereplication via multiple mechanisms in eukaryotic cells.

  2007cited by this paper
• The many faces of the origin recognition complex.

  2007cited by this paper
• The cyclin‐dependent kinase inhibitor Dacapo promotes replication licensing during Drosophila endocycles

  2007cited by this paper
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  2007cited by this paper
• Gene amplification in cancer.

  2006cited by this paper
• Isolation of the Cdc45/Mcm2–7/GINS (CMG) complex, a candidate for the eukaryotic DNA replication fork helicase

  2006cited by this paper
• HoxB domain induction silences DNA replication origins in the locus and specifies a single origin at its boundary

  2006cited by this paper
• Isolating apparently pure libraries of replication origins from complex genomes.

  2006cited by this paper
• Deregulated Replication Licensing Causes DNA Fragmentation Consistent with Head-to-Tail Fork Collision

  2006cited by this paper
• Developmental gene amplification: insights into DNA replication and gene expression.

  2005cited by this paper
• Progressive activation of DNA replication initiation in large domains of the immunoglobulin heavy chain locus during B cell development.

  2005cited by this paper
• Amplicons on human chromosome 11q are located in the early/late-switch regions of replication timing.

  2004cited by this paper
• Gene amplification as a developmental strategy: isolation of two developmental amplicons in Drosophila.

  2004cited by this paper
• Chromatin regulates origin activity in Drosophila follicle cells

  2004cited by this paper
• Coordination of replication and transcription along a Drosophila chromosome.

  2004cited by this paper
• Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells

  2003cited by this paper
• Dynamic alterations of replication timing in mammalian cells.

  2003cited by this paper
• Cyclin E ablation in the mouse.

  2003cited by this paper
• Differential expression of the Drosophila BX-C in polytene chromosomes in cells of larval fat bodies: a cytological approach to identifying in vivo targets of the homeotic Ubx, Abd-A and Abd-B proteins

  2003cited by this paper
• The Drosophila suppressor of underreplication protein binds to late-replicating regions of polytene chromosomes.

  2002cited by this paper
• Developmental Changes in the Sciara II/9A Initiation Zone for DNA Replication

  2002cited by this paper
• Cancer genetics: Women only

  2002cited by this paper
• DNA replication in eukaryotic cells.

  2002influential reference
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  2002cited by this paper
• Endoreplication cell cycles: more for less.

  2001cited by this paper
• Endoreplication cell cycles: more for less.

  2001cited by this paper
• Inhibition of eukaryotic DNA replication by geminin binding to Cdt1.

  2000cited by this paper
• Inhibition of Eukaryotic DNA Replication by Geminin Binding to Cdt1

  2000cited by this paper
• Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

  1999cited by this paper
• latheo encodes a subunit of the origin recognition complex and disrupts neuronal proliferation and adult olfactory memory when mutant.

  1999influential reference
• Evidence that a single replication fork proceeds from early to late replicating domains in the IgH locus in a non-B cell line.

  1999cited by this paper
• Su(UR)ES: a gene suppressing DNA underreplication in intercalary and pericentric heterochromatin of Drosophila melanogaster polytene chromosomes.

  1998influential reference
• Geminin, an inhibitor of DNA replication, is degraded during mitosis.

  1998cited by this paper
• The Drosophila endocycle is controlled by Cyclin E and lacks a checkpoint ensuring S-phase completion.

  1996cited by this paper
• Chromosomal replication initiates and terminates at random sequences but at regular intervals in the ribosomal DNA of Xenopus early embryos.

  1993cited by this paper
• Microtia, absent patellae, short stature, micrognathia syndrome.

  1992cited by this paper
• latheo, a new gene involved in associative learning and memory in Drosophila melanogaster, identified from P element mutagenesis.

  1992cited by this paper
• Rothmund‐Thomson syndrome

  1991cited by this paper
• Replication initiates in a broad zone in the amplified CHO dihydrofolate reductase domain.

  1990cited by this paper
• Regulation of DNA replication during Drosophila development.

  1987influential reference
• Chromosome fragile sites.

  1985cited by this paper
• Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster.

  1980cited by this paper
• The units of DNA replication in Drosophila melanogaster chromosomes.

  1974cited by this paper
• Differential replication of male and female X-chromosomes in Drosophila

  1966cited by this paper

• Molecular impacts of Meier–Gorlin syndrome mutations on human origin licensing

  2025cites this paper
• Pas de deux: the coordinated coupling of erythroid differentiation with the cell cycle

  2024cites this paper
• Cell cycle variants during Drosophila male accessory gland development

  2024cites this paper
• Inhibition of Atm and Atr kinases affects embryo development and the DNA damage response in sterlet (Acipenser ruthenus)

  2024cites this paper
• The expression spectrum of yak epididymal epithelial cells reveals the functional diversity of caput, corpus and cauda regions.

  2024cites this paper
• Responses to predation pressure involve similar sets of genes in two divergent species of Daphnia.

  2023cites this paper
• Origins of DNA replication in eukaryotes.

  2023cites this paper
• The Vast Utility of Drosophila Oogenesis.

  2023cites this paper
• DNA replication: Mechanisms and therapeutic interventions for diseases

  2023cites this paper
• DNA repair genes play a variety of roles in the development of fish embryos

  2023cites this paper
• Chronic exposure to (2 R,6 R)-hydroxynorketamine induces developmental neurotoxicity in hESC-derived cerebral organoids.

  2023cites this paper
• De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues

  2023cites this paper
• Finishing the egg.

  2023cites this paper
• The role of specialized cell cycles during erythroid lineage development: insights from single-cell RNA sequencing

  2022cites this paper
• Quantitation of Multipartite Banana Bunchy Top Virus Genomic Components and Their Transcripts in Infected Tissues of Banana (Musa acuminata)

  2022cites this paper
• GATOR2 complex–mediated amino acid signaling regulates brain myelination

  2022cites this paper
• Rif1-Dependent Control of Replication Timing

  2022cites this paper
• Simulated mutations in the geminivirus replicase gene using in-silico CRISPR / Cas9-based methods

  2021cites this paper
• Replication timing analysis in polyploid cells reveals Rif1 uses multiple mechanisms to promote underreplication in Drosophila

  2021cites this paper
• Genome Modifications Involved in Developmental Programs of the Placental Trophoblast

  2021cites this paper
• Under-Replicated DNA: The Byproduct of Large Genomes?

  2020cites this paper
• The shifting shape and functional specializations of the cell cycle during lineage development.

  2020cites this paper
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  2020cites this paper
• Reoccurring neural stem cell divisions in the adult zebrafish telencephalon are sufficient for the emergence of aggregated spatiotemporal patterns

  2020cites this paper
• Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans

  2020cites this paper
• Spatiotemporal control of cell cycle acceleration during axolotl spinal cord regeneration

  2020cites this paper
• Epigenetic regulation of replication origin assembly: A role for histone H1 and chromatin remodeling factors

  2020cites this paper
• Physiology, Development, and Disease Modeling in the Drosophila Excretory System

  2020cites this paper
• Flying High—Muscle-Specific Underreplication in Drosophila

  2020cites this paper
• Estimation of the Mutagenic Potential of 8-Oxog in Nuclear Extracts of Mouse Cells Using the “Framed Mirror” Method

  2020cites this paper
• Effects of Mutations in the Drosophila melanogaster Rif1 Gene on the Replication and Underreplication of Pericentromeric Heterochromatin in Salivary Gland Polytene Chromosomes

  2020cites this paper
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  2019cites this paper
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  2019cites this paper
• Cortical Development and Brain Malformations: Insights From the Differential Regulation of Early Events of DNA Replication

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2019cites this paper
• Nuclear Extracts of Mouse Cells Using The “Framed

  2019cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
• Xenopus egg extract to study regulation of genome‐wide and locus‐specific DNA replication

  2017cites this paper
• Nachweis von Genamplifikationen und „unter-replikation“ mittels FISH und qPCR während der Differenzierung von humanen mesenchymalen Stammzellen

  2017cites this paper
• Drosophila Larval Brain Neoplasms Present Tumour-Type Dependent Genome Instability

  2017cites this paper
• DNA Replication Control During Drosophila Development: Insights into the Onset of S Phase, Replication Initiation, and Fork Progression

  2017influential citation
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  2017cites this paper
• Rapid DNA Synthesis During Early Drosophila Embryogenesis Is Sensitive to Maternal Humpty Dumpty Protein Function

  2017cites this paper
• Polytene Chromosome Structure and Somatic Genome Instability.

  2017cites this paper
• Post-transcriptional Regulation of the Drosophila Anterior Determinant, Bicoid

  2017cites this paper
• Polyploidy in Animal Development and Disease

  2017cites this paper
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  2016cites this paper
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  2016cites this paper
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  2016cites this paper
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• Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability

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• p27Kip1 participates in the regulation of endoreplication in differentiating chick retinal ganglion cells

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• ORC4 Surrounds Extruded Chromatin in Female Meiosis

  2015cites this paper
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  2014cites this paper
• Quantifying the Length and Variance of the Eukaryotic Cell Cycle Phases by a Stochastic Model and Dual Nucleoside Pulse Labelling

  2014cites this paper
• Incomplete replication generates somatic DNA alterations within Drosophila polytene salivary gland cells

  2014cites this paper
• CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans

  2014cites this paper
• Regulatory Mechanisms That Prevent Re-initiation of DNA Replication Can Be Locally Modulated at Origins by Nearby Sequence Elements

  2014cites this paper
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  2014cites this paper
• Replication initiation and genome instability: a crossroads for DNA and RNA synthesis

  2014influential citation
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  2014cites this paper
• Endocycles: a recurrent evolutionary innovation for post-mitotic cell growth

  2014cites this paper
• Juvenile Hormone-Receptor Complex Acts on Mcm4 and Mcm7 to Promote Polyploidy and Vitellogenesis in the Migratory Locust

  2014cites this paper
• A maize root tip system to study DNA replication programmes in somatic and endocycling nuclei during plant development.

  2014cites this paper
• The scaffold protein Nde1 safeguards the brain genome during S phase of early neural progenitor differentiation

  2014influential citation
• CDK phosphorylation of SLD-2 is required for replication initiation and germline development in C. elegans

  2014cites this paper
• Differential Replication Leads to Copy Number Variation and Genome Rearrangements of Polyploid Cells

  2014cites this paper
• New insights into the maternal to zygotic transition

  2014cites this paper
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  2013cites this paper
• General and specific replication profiles are detected in normal human cells by genome-wide and single-locus molecular combing.

  2013influential citation
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2013cites this paper
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  2012cites this paper
• 2 Early evidence for a role of histone acetylation in origin regulation came from analysis of developmental gene amplification in the Drosophila ovary (

  2012cites this paper
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  2012cites this paper
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  2012cites this paper