Blockade of maitotoxin-induced endothelial cell lysis by glycine and L-alanine.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  American Journal of Physiology - Cell Physiology

• Publication date

  2003-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1152/AJPCELL.00258.2002PMID 12477666
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Maitotoxin induces insertion of different ion channels into the Xenopus oocyte plasma membrane via Ca2+-stimulated exocytosis

  2014cited by this paper
• Blockade of maitotoxin-induced oncotic cell death reveals zeiosis

  2002cited by this paper
• Glycine blocks opening of a death channel in cultured hepatic sinusoidal endothelial cells during chemical hypoxia

  2001cited by this paper
• Maitotoxin-induced membrane blebbing and cell death in bovine aortic endothelial cells

  2001cited by this paper
• A Critical Review of the Role of Endothelial Factors in the Pathogenesis of Hypertension

  2001cited by this paper
• Oxidant stress and endothelial cell dysfunction.

  2001cited by this paper
• The emerging role of glutamate in the pathophysiology and treatment of schizophrenia.

  2001cited by this paper
• Protection of ATP-depleted cells by impermeant strychnine derivatives: implications for glycine cytoprotection.

  2001cited by this paper
• Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress.

  2000cited by this paper
• Intravenous glycine improves survival in rat liver transplantation.

  1999cited by this paper
• Glycine: a new anti-inflammatory immunonutrient

  1999cited by this paper
• Maitotoxin and P 2 Z / P 2 X 7 purinergic receptor stimulation activate a common cytolytic pore

  1999cited by this paper
• Efficacy of high-dose glycine in the treatment of enduring negative symptoms of schizophrenia.

  1999cited by this paper
• Maitotoxin activates a nonselective cation channel and a P2Z/P2X7-like cytolytic pore in human skin fibroblasts.

  1999cited by this paper
• Intravenous glycine improves survival in rat liver transplantation.

  1999cited by this paper
• The mitochondrial death/life regulator in apoptosis and necrosis.

  1998cited by this paper
• Intracellular Ca2+ thresholds that determine survival or death of energy-deprived cells.

  1998cited by this paper
• Development of porous defects in plasma membranes of adenosine triphosphate-depleted Madin-Darby canine kidney cells and its inhibition by glycine.

  1998cited by this paper
• Mitochondrial dysfunction and cytoskeletal disruption during chemical hypoxia to cultured rat hepatic sinusoidal endothelial cells: The pH paradox and cytoprotection by glucose, acidotic pH, and glycine

  1998cited by this paper
• Maitotoxin (MTX) activates a nonselective cation channel in Xenopus laevis oocytes

  1998cited by this paper
• Reperfusion injury after liver preservation for transplantation.

  1997cited by this paper
• Cytosolic-free calcium increases to greater than 100 micromolar in ATP-depleted proximal tubules.

  1997cited by this paper
• The shape of cell death.

  1997cited by this paper
• Protection by Carolina rinse solution, acidotic pH, and glycine against lethal reperfusion injury to sinusoidal endothelial cells of rat livers stored for transplantation.

  1996cited by this paper
• Cytoprotection of kidney epithelial cells by compounds that target amino acid gated chloride channels.

  1996cited by this paper
• Calcium is permeable through a maitotoxin-activated nonselective cation channel in mouse L cells.

  1996cited by this paper
• Glycine in Carolina rinse solution reduces reperfusion injury, improves graft function, and increases graft survival after rat liver transplantation.

  1995cited by this paper
• Calcium‐mediated cell injury and cell death

  1995cited by this paper
• Maitotoxin activates cation channels distinct from the receptor-activated non-selective cation channels of HL-60 cells.

  1994cited by this paper
• Depletion of intracellular Ca2+ stores activates a maitotoxin-sensitive nonselective cationic current in beta-cells.

  1994cited by this paper
• Strychnine and glycine protect renal proximal tubules from various nephrotoxicants and act in the late phase of necrotic cell injury.

  1994cited by this paper
• Maitotoxin activates a nonselective cation channel and stimulates Ca2+ entry in MDCK renal epithelial cells.

  1994cited by this paper
• Inhibition of nonlysosomal calcium-dependent proteolysis by glycine during anoxic injury of rat hepatocytes.

  1994cited by this paper
• Glycine protection against hypoxic but not phospholipase A2-induced injury in rat proximal tubules.

  1993cited by this paper
• Ca2+ signaling mechanisms of vascular endothelial cells and their role in oxidant-induced endothelial cell dysfunction.

  1992cited by this paper
• Glycine cytoprotection during lethal hepatocellular injury from adenosine triphosphate depletion.

  1992cited by this paper
• Protection of human umbilical vein endothelial cells by glycine and structurally similar amino acids against calcium and hydrogen peroxide-induced lethal cell injury.

  1992cited by this paper
• Amino acid protection of cultured kidney tubule cells against calcium ionophore-induced lethal cell injury.

  1991cited by this paper
• Maitotoxin: a unique pharmacological tool for research on calcium-dependent mechanisms.

  1990cited by this paper
• Characterization of the bradykinin-stimulated calcium influx pathway of cultured vascular endothelial cells. Saturability, selectivity, and kinetics.

  1989cited by this paper
• Role of Ca2+ in toxic cell killing.

  1989cited by this paper
• Cytoprotective effects of glycine and glutathione against hypoxic injury to renal tubules.

  1987cited by this paper
• Maitotoxin, a Ca2+ channel activator candidate.

  1982cited by this paper
• Comparison of tissue-cultured bovine endothelial cells from aorta and sphenous vein

  1978cited by this paper

• Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasome-induced blood coagulation and inflammation

  2025cites this paper
• Ionotropic glycine receptor in nonexcitable cells in regenerative medicine: a narrative review

  2024cites this paper
• Inhibiting NINJ1-dependent plasma membrane rupture protects against inflammasome-induced blood coagulation and inflammation

  2023cites this paper
• Biocompatibility of hydroxyethyl cellulose/glycine/RuO2 composite scaffolds for neural-like cells.

  2022cites this paper
• Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death

  2022cites this paper
• Metabolic Regulation Effect and Potential Metabolic Biomarkers of Pre-Treated Delphinidin on Oxidative Damage Induced by Paraquat in A549 Cells

  2022cites this paper
• Glycine targets NINJ1-mediated plasma membrane rupture to provide cytoprotection

  2021influential citation
• Role Of Sericin And Its Major Amino Acids As Scavengers Of Hydrogen Peroxide Induced Oxidative Stress In A549 Cells

  2021cites this paper
• Cell death and cell lysis are separable events during pyroptosis

  2017cites this paper
• The role of glycine in regulated cell death

  2016cites this paper
• This information is current as Blocked by Lanthanides Pores That Precede Pyroptotic Lysis and Are Active Caspase-1 Induces Plasma Membrane

  2016cites this paper
• Active Caspase-1 Induces Plasma Membrane Pores That Precede Pyroptotic Lysis and Are Blocked by Lanthanides

  2016cites this paper
• BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.

  2015cites this paper
• Innovative mode of action based in vitro assays for detection of marine neurotoxins

  2015cites this paper
• The effect of liver warm ischaemia reperfusion injury and modulation on bile composition evaluated by magnetic resonance spectroscopy

  2015cites this paper
• Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling*

  2015cites this paper
• Neonatal taurine and alanine modulate anxiety-like behavior and decelerate cortical spreading depression in rats previously suckled under different litter sizes

  2015cites this paper
• The Mechanism of Action of Microalgal Toxins Interacting with NaV and KV Channels

  2014cites this paper
• Marine neurotoxins: state of the art, bottlenecks, and perspectives for mode of action based methods of detection in seafood.

  2014cites this paper
• Role of the endothelial-to-mesenchymal transition in renal fibrosis of chronic kidney disease

  2013cites this paper
• Glycine metabolism in animals and humans: implications for nutrition and health

  2013cites this paper
• Raloxifene Upregulated Mesangial Cell MMP-2 Activity via ER-β Through Transcriptional Regulation

  2013cites this paper
• Effect of Glycine on Protein Oxidation and Advanced Glycation End Products Formation

  2013cites this paper
• Signaling Events During Cyclic Guanosine Monophosphate-Regulated Pigment Aggregation in Freshwater Shrimp Chromatophores

  2012cites this paper
• Antioxidant and cytoprotective effects of L-Serine on human endothelial cells

  2012influential citation
• Therapeutic modulation of liver ischaemia reperfusion injury

  2011cites this paper
• Digestion under Duress: Nutrient Acquisition and Metabolism during Hypoxia in the Pacific Hagfish

  2011cites this paper
• Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome.

  2010cites this paper
• Renal fibrosis

  2010cites this paper
• Overexpression of Smad6 Exacerbates Pancreatic Fibrosis in Murine Caerulein-Induced Chronic Pancreatic Injuries

  2010cites this paper
• Protective effect of glycine on liver injury during liver transplantation.

  2010cites this paper
• Targeting bone morphogenetic protein signaling on renal and vascular diseases

  2010cites this paper
• Regulation of smooth muscle contraction by small GTPases.

  2009cites this paper
• The winter ulcer bacterium Moritella viscosa demonstrates adhesion and cytotoxicity in a fish cell model.

  2009cites this paper
• Glycine and Glycine Receptor Signalling in Non-Neuronal Cells

  2009cites this paper
• Role of the sodium hydrogen exchanger in maitotoxin-induced cell death in cultured rat cortical neurons.

  2009cites this paper
• Maitotoxin converts the plasmalemmal Ca(2+) pump into a Ca(2+)-permeable nonselective cation channel.

  2009cites this paper
• Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide.

  2008cites this paper
• Bone Morphogenetic Protein-7 and Connective Tissue Growth Factor: Novel Targets for Treatment of Renal Fibrosis?

  2008cites this paper
• Attenuation of maitotoxin-induced cytotoxicity in rat aortic smooth muscle cells by inhibitors of Na+/Ca2+ exchange, and calpain activation.

  2008influential citation
• Molecular mechanisms that could contribute to prolonged effectiveness of PDE5 inhibitors to improve erectile function

  2008cites this paper
• Bacillus cereus Nhe is a pore-forming toxin with structural and functional properties similar to the ClyA (HlyE, SheA) family of haemolysins, able to induce osmotic lysis in epithelia.

  2008cites this paper
• Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle.

  2008cites this paper
• Stimulatory phosphorylation of cAMP-specific PDE4D5 by contractile agonists is mediated by PKC-dependent inactivation of protein phosphatase 2A.

  2008cites this paper
• BMP-7 and Proximal Tubule Epithelial Cells: Activation of Multiple Signaling Pathways Reveals a Novel Anti-fibrotic Mechanism

  2008cites this paper
• Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells.

  2008cites this paper
• Critical Role of the Sodium Hydrogen Exchanger in Maitotoxin-Induced Neuronal Cell Death in Cultured Rat Cortical Neurons

  2008cites this paper
• Protective effect of sericin peptide against alcohol-induced gastric injury in mice.

  2008cites this paper
• Expression of connective tissue growth factor in renal tubulointerstitial fibrosis in rats and its pathogenic role

  2008cites this paper
• RhoA Prenylation Inhibitor Produces Relaxation of Tonic Smooth Muscle of Internal Anal Sphincter

  2007cites this paper
• Hyperoxic conditions inhibit airway smooth muscle myosin phosphatase in rat pups.

  2007cites this paper
• Activators of the PKA and PKG pathways attenuate RhoA-mediated suppression of the KDR current in cerebral arteries.

  2007cites this paper
• Pathophysiologie der diabetischen Nephropathie

  2007cites this paper
• Navigating pathways affecting type 1 diabetic kidney disease

  2007cites this paper
• Type III secretion translocation pores of Yersinia enterocolitica trigger maturation and release of pro‐inflammatory IL‐1β

  2007cites this paper
• Role of connective tissue growth factor in extracellular matrix degradation in renal tubular epithelial cells

  2007cites this paper
• Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK.

  2007cites this paper
• Inhibition of Galphaq-dependent PLC-beta1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2.

  2007cites this paper
• Ca2+-Independent, Inhibitory Effects of Cyclic Adenosine 5′-Monophosphate on Ca2+ Regulation of Phosphoinositide 3-Kinase C2α, Rho, and Myosin Phosphatase in Vascular Smooth Muscle

  2007cites this paper
• Recapitulation of Embryological Programmes in Renal Fibrosis – The Importance of Epithelial Cell Plasticity and Developmental Genes

  2006cites this paper
• Palytoxin-induced cell death cascade in bovine aortic endothelial cells.

  2006cites this paper
• LTBP‐1 blockade in dioxin receptor‐null mouse embryo fibroblasts decreases TGF‐β activity: Role of extracellular proteases plasmin and elastase

  2006cites this paper
• Horse chestnut extract induces contraction force generation in fibroblasts through activation of Rho/Rho kinase.

  2006cites this paper
• M2 and M3 Muscarinic Receptor Activation of Urinary Bladder Contractile Signal Transduction. I. Normal Rat Bladder

  2006cites this paper
• The role of glycine in hepatic ischemia-reperfusion injury.

  2006cites this paper
• Caspase‐1‐dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

  2006cites this paper
• Modulation of the Ca2+ sensitivity of airway smooth muscle cells in murine lung slices.

  2006cites this paper
• cGMP-dependent Protein Kinase Phosphorylates p21-activated Kinase (Pak) 1, Inhibiting Pak/Nck Binding and Stimulating Pak/Vasodilator-stimulated Phosphoprotein Association*

  2006cites this paper
• [Ca(2+)]-dependent generation of intracellular reactive oxygen species mediates maitotoxin-induced cellular responses in human umbilical vein endothelial cells.

  2006cites this paper
• Convergence of Ca2+-desensitizing mechanisms activated by forskolin and phenylephrine pretreatment, but not 8-bromo-cGMP.

  2006cites this paper
• Role of heterotrimeric G-proteins in lysophosphatidic acid-mediated neurite retraction by RhoA-dependent and -independent mechanisms in N1E-115 cells.

  2006cites this paper
• AT2 receptors cross talk with AT1 receptors through a nitric oxide- and RhoA-dependent mechanism resulting in decreased phospholipase D activity.

  2005cites this paper
• L-methionine reduces oxidant stress in endothelial cells: Role of heme oxygenase-1, ferritin, and nitric oxide

  2005cites this paper
• Regulation of tissue transglutaminase by prolonged increase of intracellular Ca2+, but not by initial peak of transient Ca2+ increase.

  2005cites this paper
• The mechanism of action of Kahalalide F: variable cell permeability in human hepatoma cell lines.

  2005cites this paper
• Myosin Phosphatase and Cofilin Mediate cAMP/cAMP-dependent Protein Kinase-induced Decline in Endothelial Cell Isometric Tension and Myosin II Regulatory Light Chain Phosphorylation*

  2005cites this paper
• Bone Morphogenetic Protein-7 Signals Opposing Transforming Growth Factor β in Mesangial Cells*

  2004cites this paper
• Connective tissue growth factor and renal diseases: some answers, more questions

  2004cites this paper
• Role of Ca 2+ -Permeable Cation Channels in Ca 2+ Signalling and Necrotic Cell Death

  2004influential citation
• AND NECROTIC CELL DEATH

  2004cites this paper
• Activation of PLC-δ1 by Gi/o-coupled receptor agonists

  2004cites this paper
• Maitotoxin-induced cell death cascade in bovine aortic endothelial cells: divalent cation specificity and selectivity.

  2004cites this paper
• New insights into the pathophysiology of diabetic nephropathy: from haemodynamics to molecular pathology

  2004cites this paper
• Activation of PLC-delta1 by Gi/o-coupled receptor agonists.

  2004cites this paper
• Mechanisms of ADRF release from rat aortic adventitial adipose tissue.

  2004cites this paper
• Antioxidant action of L-alanine: heme oxygenase-1 and ferritin as possible mediators.

  2004cites this paper
• Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease

  2004cites this paper
• Bone morphogenetic protein-7 signals opposing transforming growth factor beta in mesangial cells.

  2004cites this paper
• cAMP protects endothelial barrier functions by preventing Rac-1 inhibition.

  2004cites this paper
• Maitotoxin induces biphasic interleukin-1beta secretion and membrane blebbing in murine macrophages.

  2004cites this paper
• Growth factors and the development of diabetic nephropathy

  2003cites this paper