Patterns of brain activity associated with variation in voluntary wheel-running behavior.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Behavioral Neuroscience

• Publication date

  2003-12-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1037/0735-7044.117.6.1243PMID 14674844
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Number of Arginine-Vasopressin Neurons in the Suprachiasmatic Nuclei Is Not Related to Level or Circadian Characteristics of Wheel-Running Activity in House Mice

  2004cited by this paper
• The mouse brain in stereotaxic coordinates

  2003cited by this paper
• Neural Activation Profile Elicited by Cues Associated with the Anxiogenic Drug Yohimbine Differs from That Observed for Reward-Paired Cues

  2003cited by this paper
• Artificial selection for high activity favors mighty mini-muscles in house mice.

  2003cited by this paper
• Differential sensitivity to acute administration of Ritalin, apormorphine, SCH 23390, but not raclopride in mice selectively bred for hyperactive wheel-running behavior

  2003cited by this paper
• Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running.

  2003influential reference
• ΔFosB Regulates Wheel Running

  2002influential reference
• EVOLUTION OF A SMALL‐MUSCLE POLYMORPHISM IN LINES OF HOUSE MICE SELECTED FOR HIGH ACTIVITY LEVELS

  2002cited by this paper
• ANATOMICAL SUBSTRATES OF OREXIN ^ DOPAMINE INTERACTIONS : LATERAL HYPOTHALAMIC PROJECTIONS TO THE VENTRAL TEGMENTAL AREA

  2002cited by this paper
• Plasma corticosterone response to acute and chronic voluntary exercise in female house mice.

  2002influential reference
• EVOLUTION OF A SMALL-MUSCLE POLYMORPHISM IN LINES OF HOUSE MICE SELECTED FOR HIGH ACTIVITY LEVELS

  2002cited by this paper
• Effect of Simple Motor Performance on Regional Dopamine Release in the Striatum in Parkinson Disease Patients and Healthy Subjects: A Positron Emission Tomography Study

  2002cited by this paper
• Selection experiments: an under-utilized tool in biomechanics and organismal biology

  2002influential reference
• The Neuroscience of Natural Rewards: Relevance to Addictive Drugs

  2002cited by this paper
• On counting and counting errors

  2002cited by this paper
• Delta FosB regulates wheel running.

  2002influential reference
• A common profile of prefrontal cortical activation following exposure to nicotine- or chocolate-associated contextual cues.

  2001cited by this paper
• Selection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus).

  2001influential reference
• Genetic selection of mice for high voluntary wheel running: effect on skeletal muscle glucose uptake.

  2001cited by this paper
• Differential sensitivity to acute administration of cocaine, GBR 12909, and fluoxetine in mice selectively bred for hyperactive wheel-running behavior

  2001influential reference
• Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action.

  2001cited by this paper
• Location and distribution of Fos protein expression in rat hippocampus following acute moderate aerobic exercise

  2001influential reference
• DeltaFosB: a sustained molecular switch for addiction.

  2001influential reference
• ΔFosB: A sustained molecular switch for addiction

  2001influential reference
• The elevation of plasma adrenocorticotrophic hormone and expression of c-Fos in hypothalamic paraventricular nucleus by microinjection of neostigmine into the hippocampus in rats: comparison with acute stress responses.

  2001influential reference
• The general matching law describes choice on concurrent variable-interval schedules of wheel-running reinforcement.

  2001cited by this paper
• cFOS and pCREB activation and maternal aggression in mice.

  2001influential reference
• Patterns of Wheel Running Are Related to Fos Expression in Neuropeptide-Y-Containing Neurons in the Intergeniculate Leaflet of Arvicanthis niloticus

  2001cited by this paper
• Mixed-Effects Models in S and S-Plus

  2001influential reference
• Effects of voluntary activity and genetic selection on muscle metabolic capacities in house mice Mus domesticus.

  2000cited by this paper
• Convergent Inputs from Thalamic Motor Nuclei and Frontal Cortical Areas to the Dorsal Striatum in the Primate

  2000cited by this paper
• THE PREFRONTAL CORTEX AND COGNITIVE CONTROL

  2000cited by this paper
• Body temperatures of house mice artificially selected for high voluntary wheel-running behavior: repeatability and effect of genetic selection.

  2000cited by this paper
• Pairings of a distinctive chamber with the aftereffect of wheel running produce conditioned place preference.

  2000influential reference
• The prefontral cortex and cognitive control

  2000cited by this paper
• Fos in the Suprachiasmatic Nucleus of House Mouse Lines That Reveal a Different Phase-Delay Response to the Same Light Pulse

  2000cited by this paper
• Locomotor activity and accumbens Fos expression driven by ventral hippocampal stimulation require D1 and D2 receptors.

  1999influential reference
• Artificial Selection for Increased Wheel-Running Behavior in House Mice

  1998influential reference
• Using c-fos as a neural marker of pain.

  1998influential reference
• Expression of Fos in the circadian system following nonphotic stimulation.

  1998cited by this paper
• Voluntary wheel running: a review and novel interpretation.

  1998cited by this paper
• Neuronal mechanisms for generating locomotor activity

  1998influential reference
• The frequency of rat's hippocampal theta rhythm is related to the speed of locomotion.

  1998influential reference
• Hippocampal formation theta activity and movement selection.

  1998influential reference
• Phosphorylation of Transcription Factor CREB in Rat Spinal Cord after Formalin-Induced Hyperalgesia: Relationship toc-fos Induction

  1997influential reference
• Spurious Associations in Unreplicated Selected Lines

  1997cited by this paper
• Release of dopamine in the nucleus accumbens caused by stimulation of the subiculum in freely moving rats.

  1997cited by this paper
• Treadmill running induces striatal Fos expression via NMDA glutamate and dopamine receptors

  1997cited by this paper
• Identification of diencephalic and brainstem cardiorespiratory areas activated during exercise.

  1996cited by this paper
• Role of the cerebral cortex and striatum in emotional motor response.

  1996cited by this paper
• Gene expression during ethanol withdrawal.

  1994cited by this paper
• Techniques for establishing schedules with wheel running as reinforcement in rats.

  1993influential reference
• Fos and jun in rat central amygdaloid nucleus and paraventricular nucleus after stress.

  1992cited by this paper
• Early induction of c-fos precedes increased expression of corticotropin-releasing factor messenger ribonucleic acid in the paraventricular nucleus after immobilization stress.

  1992cited by this paper
• Individual variation in locomotor behavior and maximal oxygen consumption in mice.

  1992cited by this paper
• The use of c-fos as a metabolic marker in neuronal pathway tracing.

  1989cited by this paper
• Interpreting studies that compare high- and low-selected lines on new characters

  1989cited by this paper
• Expression of c-fos protein in brain: metabolic mapping at the cellular level.

  1988cited by this paper
• Locomotion elicited by lateral hypothalamic stimulation in the anesthetized rat does not require the dorsal midbrain.

  1987cited by this paper
• Neurobiology of the hippocampus

  1983cited by this paper
• The contributions of position, direction, and velocity to single unit activity in the hippocampus of freely-moving rats

  1983cited by this paper
• Normal jump avoidance performance in rats with the hippocampal theta rhythm selectively disrupted.

  1975cited by this paper
• Relationship between hippocampal theta activity and running speed in the rat.

  1975cited by this paper
• Hippocampal activity, behavior, self-stimulation, and heart rate during electrical stimulation of the lateral hypothalamus.

  1972cited by this paper
• Hippocampal electrical activity and voluntary movement in the rat.

  1969influential reference
• ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 860: 83-93 (1998) Initiation of Locomotion in Mammals

  year unknowninfluential reference

• Medial nucleus accumbens dopamine receptors modulate motivation for wheel running in male mice

  2025cites this paper
• The GLP-1R Agonist Semaglutide Reduces Motivated Running and Alters Dopamine Dynamics in the Nucleus Accumbens

  2025cites this paper
• More running causes more ocular dominance plasticity in mouse primary visual cortex: new gated running wheel setup allows to quantify individual running behaviour of group-housed mice

  2025cites this paper
• Maternal exercise opportunity before, during, and after pregnancy alters maternal care behavior and offspring development and survival, but has few effects on offspring physical activity or body composition.

  2024cites this paper
• Estrogen-mediated individual differences in female rat voluntary running behavior.

  2024cites this paper
• Single‐Nucleus RNA Sequencing Reveals Enduring Signatures of Acute Stress and Chronic Exercise in Striatal Microglia

  2024cites this paper
• Atlas of exercise-induced brain activation in mice

  2024cites this paper
• Hippocampal long-term potentiation is modulated by exercise-induced alterations in dopaminergic synaptic transmission in mice selectively bred for high voluntary wheel running

  2024influential citation
• Activation of ventral pallidum-projecting neurons in the nucleus accumbens via 5-HT2C receptor stimulation regulates motivation for wheel running in male mice.

  2024cites this paper
• Maternal upbringing and selective breeding for voluntary exercise behavior modify patterns of DNA methylation and expression of genes in the mouse brain

  2023cites this paper
• Pathophysiological mechanisms of reduced physical activity: Insights from the human step reduction model and animal analogues

  2023cites this paper
• The different cell-specific mechanisms of voluntary exercise and forced exercise in the nucleus accumbens.

  2023cites this paper
• Humans have a basic physical and psychological need to move the body: Physical activity as a primary drive

  2023cites this paper
• Decoding behavior from global cerebrovascular activity using neural networks

  2023cites this paper
• Hippocampal, Whole Midbrain, Red Nucleus, and Ventral Tegmental Area Volumes Are Increased by Selective Breeding for High Voluntary Wheel-Running Behavior

  2023influential citation
• Transcriptomic analysis reveals novel molecular signaling networks in response to nucleus accumbens AP-1 inhibition in rats selectively bred for low voluntary wheel running behavior.

  2022cites this paper
• Regulation of Voluntary Physical Activity Behavior: A Review of Evidence Involving Dopaminergic Pathways in the Brain

  2022cites this paper
• A red nucleus–VTA glutamate pathway underlies exercise reward and the therapeutic effect of exercise on cocaine use

  2022cites this paper
• Octopamine affects courtship call structure in male Acheta domesticus crickets.

  2022cites this paper
• The association of catechol-O-methyltransferase genetic polymorphism rs4680 in physical activity among adult women

  2022cites this paper
• A spatiotemporal increase of neuronal activity accompanies the motivational effect of wheel running in mice.

  2022cites this paper
• Differences in running performance of single- and group-housed mice

  2021cites this paper
• Exercise hormone irisin is a critical regulator of cognitive function

  2021cites this paper
• Exercise hormone irisin is a critical regulator of cognitive function

  2021cites this paper
• Hippocampal neurons respond to brain activity with functional hypoxia

  2021cites this paper
• Modulation of Synaptic Plasticity by Vibratory Training in Young and Old Mice

  2021cites this paper
• Temporal and bidirectional influences of estradiol on voluntary wheel running in adult female and male rats.

  2020cites this paper
• Genetic Basis of Aerobically Supported Voluntary Exercise: Results from a Selection Experiment with House Mice

  2020cites this paper
• Behavioral phenotyping of mice lacking the deubiquitinase USP2

  2020cites this paper
• Loss of habenular Prkar2a reduces hedonic eating and increases exercise motivation

  2020cites this paper
• Voluntary wheel running ameliorates select paclitaxel chemotherapy-induced sickness behaviors and associated melanocortin signaling.

  2020cites this paper
• Coadaptation of the chemosensory system with voluntary exercise behavior in mice

  2020cites this paper
• Conditioned place preference for cocaine and methylphenidate in female mice from lines selectively bred for high voluntary wheel‐running behavior

  2020cites this paper
• Role of glucocorticoid signaling in exercise-associated changes in high-fat diet preference in rats

  2020cites this paper
• Influence of corticosterone on growth, home-cage activity, wheel running, and aerobic capacity in house mice selectively bred for high voluntary wheel-running behavior.

  2019cites this paper
• Neurogenetics of Motivation for Physical Activity

  2019cites this paper
• Acute and long-term treadmill running differentially induce c-Fos expression in region- and time-dependent manners in mouse brain

  2019cites this paper
• Defining Microbial Signatures of Gut Dysbiosis in Models of Anxiety-related Disorders

  2019cites this paper
• Effects of short-term aerobic exercise in a mouse model of Niemann-Pick type C disease on synaptic and muscle plasticity.

  2019cites this paper
• Electrocardiograms of mice selectively bred for high levels of voluntary exercise: Effects of short-term exercise training and the mini-muscle phenotype.

  2019cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• A new perspective of the hippocampus in the origin of exercise–brain interactions

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents: are we running in the right direction?

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus

  2018cites this paper
• Predicting the ergogenic response to methylphenidate

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Voluntary wheel running: patterns and physiological effects in mice

  2018cites this paper
• The influence of methylphenidate on heart rate and brain connectivity

  2018cites this paper
• Androgen and estrogen actions on male physical activity: a story beyond muscle.

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• Brain region-dependent gene networks associated with selective breeding for increased voluntary wheel-running behavior

  2018cites this paper
• Exploring Exercise- and Context-Induced Peptide Changes in Mice by Quantitative Mass Spectrometry

  2018cites this paper
• Voluntary exercise and depression-like behavior in rodents : are we running in the right direction ?

  2018cites this paper
• High-runner mice have reduced incentive salience for a sweet-taste reward when housed with wheel access.

  2018cites this paper
• Rapid Reacquisition of Contextual Fear Conditioning: The Behavior, Interaction with Alcohol, and Neurobiology

  2018cites this paper
• Mechanisms Associated With Physical Activity Behavior: Insights From Rodent Experiments

  2017cites this paper
• Clinical Research and Practice

  2017cites this paper
• The Neurobiological Basis of Voluntary Exercise in Selectively-Bred High Runner Mice

  2017cites this paper
• High motivation for exercise is associated with altered chromatin regulators of monoamine receptor gene expression in the striatum of selectively bred mice

  2017influential citation
• Social dominance and wheel running in females of Djungarian hamster (Phodopus sungorus)

  2017cites this paper
• Title: EFFECTS OF PHYSICAL EXERCISE AND SOCIAL ISOLATION ON ANXIETY-RELATED BEHAVIORS IN TWO INBRED RAT STRAINS

  2017cites this paper
• Circulating levels of endocannabinoids respond acutely to voluntary exercise, are altered in mice selectively bred for high voluntary wheel running, and differ between the sexes.

  2017cites this paper
• 5‐Aminoimidazole‐4‐carboxamide ribonucleotide prevents fat gain following the cessation of voluntary physical activity

  2017cites this paper
• Fight, flight or finished: forced fitness behaviours in Game of Thrones

  2017cites this paper
• Curcumin limits weight gain, adipose tissue growth, and glucose intolerance following the cessation of exercise and caloric restriction in rats.

  2017cites this paper
• Exercise Strategies to Counteract Brain Aging Effects.

  2017cites this paper
• A disparity between locomotor economy and territory-holding ability in male house mice

  2017cites this paper
• Effects of physical exercise and social isolation on anxiety-related behaviors in two inbred rat strains.

  2017cites this paper
• Caffeine stimulates voluntary wheel running in mice without increasing aerobic capacity.

  2017cites this paper
• The effects of voluntary wheel running on neuroinflammatory status: Role of monocyte chemoattractant protein‐1

  2017cites this paper
• Metabolic hormones and physical activity as regulators of brain glial cell functions and neuroimmune status

  2017cites this paper
• Sex‐dependent differences in voluntary physical activity

  2017influential citation
• Genetic architecture of motives for leisure‐time physical activity: a twin study

  2017cites this paper
• Long-Lasting Effects of Early-Onset Exercise on the Prevention of Obesity and Its Related Lifestyle Diseases

  2016cites this paper
• Spatial learning and neurogenesis: Effects of cessation of wheel running and survival of novel neurons by engagement in cognitive tasks

  2016cites this paper
• Parameters for abolishing conditioned place preference for cocaine from running and environmental enrichment in male C57BL/6J mice.

  2016cites this paper
• Cerebellum Transcriptome of Mice Bred for High Voluntary Activity Offers Insights into Locomotor Control and Reward-Dependent Behaviors

  2016cites this paper
• Animal Models of Exercise–Brain Interactions

  2016cites this paper
• Serotonin-mediated central fatigue underlies increased endurance capacity in mice from lines selectively bred for high voluntary wheel running.

  2016cites this paper
• Effects of a maternal high-fat diet on offspring behavioral and metabolic parameters in a rodent model

  2016cites this paper
• Anxiety is correlated with running in adolescent female mice undergoing activity-based anorexia.

  2015cites this paper
• Intrinsic exercise capacity is related to differential monoaminergic activity in the rat forebrain.

  2015cites this paper
• Age‐dependent alterations of the NMDA receptor developmental profile and adult behavior in postnatally ketamine‐treated mice

  2015cites this paper
• The 'Omics' of Voluntary Exercise: Systems Approaches to a Complex Phenotype.

  2015cites this paper
• Increased adult hippocampal neurogenesis is not necessary for wheel running to abolish conditioned place preference for cocaine in mice

  2015cites this paper
• Effects of physical exercise and exercise-induced adult hippocampal neurogenesis on conditioned place preference for cocaine in mice

  2015influential citation
• Developmental programming of energy balance regulation: is physical activity more ‘programmable’ than food intake?

  2015cites this paper
• Sex-dependent effects of developmental exposure to bisphenol A and ethinyl estradiol on metabolic parameters and voluntary physical activity

  2015cites this paper
• Cthrc1 controls adipose tissue formation, body composition, and physical activity

  2015cites this paper
• Exercise reward induces appetitive 50-kHz calls in rats.

  2015cites this paper
• Evaluating Exercise as a Therapeutic Intervention for Methamphetamine Addiction-Like Behavior1

  2015cites this paper
• On the Neurobiology of Physical Activity in Mice and Human : In search of Eating Disorders Determinants

  2014cites this paper
• Genetic factors in exercise adoption, adherence and obesity

  2014cites this paper
• Humanized animal exercise model for clinical implication

  2014cites this paper
• Effects of acute bouts of physical activity on children's attention: a systematic review of the literature

  2014cites this paper