Gravity sensing by cells: mechanisms and theoretical grounds

No abstract is available for this paper.

• Publication year

  2014

• Venue

  RENDICONTI LINCEI

• Publication date

  2014-01-18

• Fields of study

  Physics, Environmental Science

• Identifiers
  DOI 10.1007/s12210-013-0281-x
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• Gene expression in space

  1999cited by this paper
• Nonequilibrium / nonlinear chemical oscillation in the virtual absence of gravity.

  1999influential reference
• Growth factor‐induced signal transduction in adherent mammalian cells is sensitive to gravity

  1999cited by this paper
• Direct Observations of the Mechanical Behaviors of the Cytoskeleton in Living Fibroblasts

  1999cited by this paper
• Molecular and cellular biology of bone

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  1998cited by this paper
• Growing tissues in microgravity

  1998cited by this paper
• Cellular responses to gravity: extracellular, intracellular and in-between.

  1998cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Effect of spaceflight on human stem cell hematopoiesis: suppression of erythropoiesis and myelopoiesis

  1996cited by this paper
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  1996cited by this paper
• The theoretical consideration of microgravity effects on a cell.

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• Influence of altered gravity on brain cellular energy and plasma membrane metabolism of developing lower aquatic vertebrates.

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  1996cited by this paper
• Free and membrane-bound calcium in microgravity and microgravity effects at the membrane level.

  1996cited by this paper
• Convergence of integrin and growth factor receptor signaling pathways within the focal adhesion complex.

  1995influential reference
• SCALE INVARIANCE, INTERFACES AND NON-EQUILIBRIUM DYNAMICS

  1995cited by this paper
• GENERIC SCALE INVARIANCE AND SELF-ORGANIZED CRITICALITY

  1995cited by this paper
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  1995cited by this paper
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  1994cited by this paper
• Morphological bifurcations involving reaction-diffusion processes during microtubule formation.

  1994cited by this paper
• Statistical mechanics in biology: how ubiquitous are long-range correlations?

  1994cited by this paper
• Biological role of gravity: hypotheses and results of experiments on "Cosmos" biosatellites.

  1992cited by this paper
• Possible actions of gravity on the cellular machinery.

  1992cited by this paper
• Reduced lymphocyte activation in space: role of cell-substratum interactions.

  1992cited by this paper
• Theories and models of biological response to gravity: an introduction.

  1992cited by this paper
• Gravity detection through bifurcation.

  1992influential reference
• Possible mechanisms of indirect gravity sensing by cells.

  1991cited by this paper

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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
• Journey to Mars: A Biomedical Challenge. Perspective on future human space flight

  2017cites this paper
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