A Comparative Review of Methods for T Cell Depletion in the Prophylaxis of Graft-versus-Host Disease

No abstract is available for this paper.

• Publication year

  1998

• Venue

  BioDrugs

• Publication date

  1998-02-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2165/00063030-199809020-00003PMID 18020549
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Randomized controlled trial

  2016cited by this paper
• Allogeneic transplantation with CD34+-selected cells.

  1997cited by this paper
• CD6-depleted allogeneic bone marrow transplantation for acute leukemia in first complete remission.

  1997influential reference
• Allogeneic blood stem cell transplantation

  1997cited by this paper
• Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia

  1997cited by this paper
• Rapid engraftment without significant graft-versus-host disease after allogeneic transplantation of CD34+ selected cells from peripheral blood.

  1997influential reference
• A phase II trial of partially incompatible bone marrow transplantation for high-risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti-LFA-1 and anti-CD2 antibodies. Société Française de Greffe de Moelle Osseuse.

  1996cited by this paper
• Transplantation of allogeneic CD34+ peripheral blood stem cells in patients with advanced hematologic malignancy.

  1996cited by this paper
• Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.

  1996influential reference
• Unrelated donor bone marrow transplantation for children with relapsed acute lymphoblastic leukaemia in second complete remission

  1996influential reference
• A phase II trial of partially incompatible bone marrow transplantation for high‐risk acute lymphoblastic leukaemia in children: prevention of graft rejection with anti‐LFA‐1 and anti‐CD2 antibodies

  1996influential reference
• Allogeneic transplantation of positively selected peripheral blood CD34+ progenitor cells from matched related donors.

  1996cited by this paper
• Natural killer (NK)-cell function and antileukemic activity of a large population of CD3+/CD8+ T cells expressing NK receptors for major histocompatibility complex class I after "three-loci" HLA-incompatible bone marrow transplantation.

  1996influential reference
• Combined in vitro and in vivo T lymphocyte depletion for the control of graft-versus-host disease following haploidentical marrow transplant.

  1996influential reference
• The development of cellular immunity to Epstein-Barr virus after allogeneic bone marrow transplantation.

  1996cited by this paper
• Transplantation of allogeneic CD34+ blood cells.

  1996cited by this paper
• Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient.

  1995influential reference
• Pretreatment of donor mice with granulocyte colony-stimulating factor polarizes donor T lymphocytes toward type-2 cytokine production and reduces severity of experimental graft-versus-host disease.

  1995cited by this paper
• Bone marrow transplantation across HLA barriers by increasing the number of transplanted cells.

  1995cited by this paper
• Adoptive immunotherapy using donor leukocytes following bone marrow transplantation for chronic myeloid leukemia: is T cell dose important in determining biological response?

  1995cited by this paper
• In vivo/ex vivo T cell depletion for GVHD prophylaxis influences onset and course of active cytomegalovirus infection and disease after BMT.

  1995cited by this paper
• Adoptive immunotherapy evaluating escalating doses of donor leukocytes for relapse of chronic myeloid leukemia after bone marrow transplantation: separation of graft-versus-leukemia responses from graft-versus-host disease.

  1995cited by this paper
• Presence of host-specific interleukin 2-secreting T helper cell precursors correlates closely with active primary and secondary chronic graft-versus-host disease.

  1995influential reference
• Primary transplantation of allogeneic peripheral blood progenitor cells mobilized by filgrastim (granulocyte colony-stimulating factor)

  1995cited by this paper
• Use of unrelated marrow grafts compensates for reduced graft-versus-leukemia reactivity after T-cell-depleted allogeneic marrow transplantation for chronic myelogenous leukemia.

  1995influential reference
• Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients.

  1995cited by this paper
• Combined transplantation of allogeneic bone marrow and CD34+ blood cells.

  1995cited by this paper
• Successful therapy with donor buffy coat transfusions in patients with relapsed chronic myeloid leukemia after bone marrow transplantation is associated with high frequencies of host-reactive interleukin 2-secreting T helper cells.

  1995cited by this paper
• T‐cell‐depleted allogeneic bone marrow transplantation for acute leukaemia using Campath‐1 antibodies and post‐transplant administration of donor's peripheral blood lymphocytes for prevention of relapse

  1995influential reference
• Transplantation of t‐lymphocyte depleted marrow with an addback of T cells

  1995cited by this paper
• Optimizing the Composition of Bone Marrow for Allogeneic Transplantation

  1995cited by this paper
• Clinical trials with CAMPATH-I and other monoclonal antibodies.

  1995cited by this paper
• Predicting graft-versus-host disease.

  1995influential reference
• In vivo/ex vivo T cell depletion reduces the morbidity of allogeneic bone marrow transplantation in patients with acute leukaemias in first remission without increasing the risk of treatment failure: comparison with cyclosporin/methotrexate.

  1995cited by this paper
• G-CSF-mobilized peripheral blood progenitor cells for allogeneic transplantation: comparison of T cell depletion strategies using different CD34+ selection systems or CAMPATH-1.

  1995cited by this paper
• Allogeneic blood stem cell transplantation: peripheralization and yield of donor-derived primitive hematopoietic progenitor cells (CD34+ Thy-1dim) and lymphoid subsets, and possible predictors of engraftment and graft-versus-host disease.

  1995cited by this paper
• CD8-depleted donor lymphocyte infusion as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation.

  1995cited by this paper
• Successful engraftment of T-cell-depleted haploidentical "three-loci" incompatible transplants in leukemia patients by addition of recombinant human granulocyte colony-stimulating factor-mobilized peripheral blood progenitor cells to bone marrow inoculum.

  1994cited by this paper
• Allogeneic bone marrow transplantation with a fixed low number of T cells in the marrow graft [see comments]

  1994cited by this paper
• Control of graft-versus-host disease and graft rejection by T cell depletion of donor and recipient with Campath-1 antibodies. Results of matched sibling transplants for malignant diseases.

  1994influential reference
• T cell depletion by exposure to Campath-1G in vitro prevents graft-versus-host disease.

  1994cited by this paper
• Marrow transplants from HLA matched unrelated donors: an NMDP update and the Seattle experience.

  1994cited by this paper
• Long-term follow-up of a randomized trial comparing T cell depletion with a combination of methotrexate and cyclosporine in adult leukemic marrow transplant recipients.

  1994influential reference
• SELECTIVE DEPLETION OF CD8+ CELLS FOR PREVENTION OF GRAFT‐VERSUS-HOST DISEASE AFTER BONE MARROW TRANSPLANTATION A RANDOMIZED CONTROLLED TRIAL

  1994influential reference
• Ganciclovir treatment of herpes simplex thymidine kinase-transduced primary T lymphocytes: an approach for specific in vivo donor T-cell depletion after bone marrow transplantation?

  1994cited by this paper
• Bone Marrow Donors Worldwide: a successful exercise in international cooperation.

  1994cited by this paper
• Effect of T-cell depletion as graft-versus-host disease prophylaxis on engraftment, relapse, and disease-free survival in unrelated marrow transplantation for chronic myelogenous leukemia.

  1994influential reference
• Mixed chimerism after bone marrow transplantation and the risk of relapse.

  1994cited by this paper
• Immunomagnetic CD8 depletion.

  1994cited by this paper
• Allogeneic bone marrow transplantation with a fixed low number of T-cells in the marrow graft.

  1994cited by this paper
• Allogeneic bone marrow transplantation with a fixed low number of T cells in the marrow graft.

  1994influential reference
• Angiotensin II AT2 Receptor Stimulation Extends the Upper Limit of Cerebral Blood Flow Autoregulation: Agonist Effects of CGP 42112 and PD 123319

  1994cited by this paper
• Allogeneic bone marrow transplantation with a fixed low number of T- cells in the marrow graft [letter; comment]

  1994cited by this paper
• Matched unrelated donor bone marrow transplantation for chronic myeloid leukaemia in chronic phase: comparison of ex vivo and in vivo T-cell depletion.

  1993cited by this paper
• Characterization of mixed chimerism in patients with chronic myeloid leukemia transplanted with T-cell-depleted bone marrow: involvement of different hematologic lineages before and after relapse.

  1993cited by this paper
• Biology of graft-vs.-host disease.

  1993cited by this paper
• Selective depletion of CD8-positive T-lymphocytes for allogeneic bone marrow transplantation: engraftment, graft-versus-host disease and graft-versus leukemia.

  1992influential reference
• Prevention of graft-versus-host disease by selective depletion of CD6-positive T lymphocytes from donor bone marrow.

  1992cited by this paper
• Prevention of graft-versus-host disease by using immunotoxins.

  1992influential reference
• T-cell-depleted allogeneic bone marrow transplantation in adults with acute nonlymphocytic leukemia in first remission.

  1992cited by this paper
• Alloimmune effects of bone marrow transplantation for leukaemia on the leukaemic diseases.

  1991cited by this paper
• Reduction of graft failure by a monoclonal antibody (anti-LFA-1 CD11a) after HLA nonidentical bone marrow transplantation in children with immunodeficiencies, osteopetrosis, and Fanconi's anemia: a European Group for Immunodeficiency/European Group for Bone Marrow Transplantation report.

  1991cited by this paper
• Alloimmune effects of bone marrow transplantation for leukaemia on the leukaemic diseases.

  1991cited by this paper
• Selective depletion of bone marrow T lymphocytes with anti-CD5 monoclonal antibodies: effective prophylaxis for graft-versus-host disease in patients with hematologic malignancies.

  1991cited by this paper
• T-cell depletion of HLA-identical transplants in leukemia.

  1991influential reference
• Allogeneic bone marrow transplantation for leukemia with marrow grafts depleted of lymphocytes by counterflow centrifugation.

  1990influential reference
• Donor leukocyte transfusions for treatment of recurrent chronic myelogenous leukemia in marrow transplant patients.

  1990influential reference
• Successful allogeneic transplantation of T-cell-depleted bone marrow from closely HLA-matched unrelated donors.

  1990cited by this paper
• Bone marrow graft engineering by counterflow centrifugal elutriation: results of a phase I-II clinical trial.

  1990influential reference
• T‐CELL DEPLETION OF HUMAN BONE MARROW

  1989cited by this paper
• Cell-type-specific cytotoxicity of anti-CD4 and anti-CD8 ricin immunotoxins against human alloreactive T-cell clones.

  1989cited by this paper
• T cell depletion of human bone marrow. Comparison of Campath-1 plus complement, anti-T cell ricin A chain immunotoxin, and soybean agglutinin alone or in combination with sheep erythrocytes or immunomagnetic beads.

  1989influential reference
• Selective depletion of CD8 positive T-lymphocytes for prevention of graft-versus-host disease following allogeneic bone marrow transplantation.

  1989cited by this paper
• Mixed hematopoietic chimerism after allogeneic transplantation with lymphocyte-depleted bone marrow is not associated with a higher incidence of relapse.

  1989cited by this paper
• GRAFT STABILITY IN A HEART TRANSPLANT RECIPIENT WHOSE IMMUNOSUPPRESSIVE THERAPY WAS DISCONTINUED FOR 8 MONTHS1

  1988cited by this paper
• T CELL DEPLETION WITH CAMPATH‐1 IN ALLOGENEIC BONE MARROW TRANSPLANTATION

  1988influential reference
• A new multichamber counterflow centrifugation rotor with high-separation capacity and versatile potentials.

  1988cited by this paper
• T‐cell depletion versus methotrexate as GvHD‐prophylaxis in allogeneic bone marrow transplantation for leukaemia

  1988cited by this paper
• Additional total-lymphoid irradiation in preventing graft failure of T-cell-depleted bone marrow transplantation from HLA-identical siblings. Results of a prospective randomized study.

  1988cited by this paper
• Lymphocyte depletion of donor bone marrow by counterflow centrifugal elutriation: results of a phase I clinical trial.

  1988influential reference
• Epstein-Barr virus associated B cell lymphoproliferative disorders following bone marrow transplantation.

  1988cited by this paper
• Marrow transplantation from HLA non‐identical family donors for the treatment of leukaemia: a pilot study of 15 patients using additional immunosuppression and T‐cell depletion

  1988cited by this paper
• Quantity and nature of residual bone marrow T cells after treatment of the marrow with Campath-1.

  1987cited by this paper
• Prevention of graft-versus-host disease in HLA-matched bone marrow transplantation for malignant diseases: a multicentric study of 62 patients using 3-pan-T monoclonal antibodies and rabbit complement.

  1987cited by this paper
• Impact of T-cell depletion on outcome of allogeneic bone-marrow transplantation for standard-risk leukaemias.

  1987influential reference
• SPECIFIC EX‐VIVO DEPLETION OF HUMAN BONE MARROW T LYMPHOCYTES BY AN ANTI‐PAN‐T CELL (CD5) RICINA‐CHAIN IMMUNOTOXIN

  1987cited by this paper
• Successful graft-versus-host disease prevention without graft failure in 32 HLA-identical allogeneic bone marrow transplantations with marrow depleted of T cells by monoclonal antibodies and complement.

  1987influential reference
• Human marrow T cell dose correlates with severity of subsequent acute graft-versus-host disease.

  1987cited by this paper
• Graft-versus-host disease prevention in allogeneic bone marrow transplantation from histocompatible siblings. A pilot study using immunotoxins for T cell depletion of donor bone marrow.

  1987cited by this paper
• Treatment of donor bone marrow with monoclonal anti-T-cell antibody and complement for the prevention of graft-versus-host disease. A prospective, randomized, double-blind trial.

  1986influential reference
• Engraftment rates related to busulphan and cyclophosphamide dosages for displacement bone marrow transplants in fifty children.

  1986cited by this paper
• Bone marrow transplantation for patients with chronic myeloid leukaemia: T-cell depletion with Campath-1 reduces the incidence of graft-versus-host disease but may increase the risk of leukaemic relapse.

  1986cited by this paper
• Graft-versus-host disease following transplantation of 'one log' versus 'two log' T-lymphocyte-depleted bone marrow from HLA-identical donors.

  1986influential reference
• Clonable T lymphocytes in T cell-depleted bone marrow transplants correlate with development of graft-v-host disease.

  1986cited by this paper
• FUNCTIONAL ASSESSMENT OF T CELL DEPLETION FROM BONE MARROW PRIOR TO THERAPEUTIC TRANSPLANTATION USING LIMITING DILUTION CULTURE METHODS

  1986cited by this paper
• Quantitative assays for detection of residual T cells of T-depleted human marrow.

  1985cited by this paper
• Effects of in vitro depletion of T cells in HLA-identical allogeneic marrow grafts.

  1985influential reference
• QUANTITATION OF T LYMPHOCYTES IN HUMAN BONE MARROW BY A LIMITING DILUTION ASSAY

  1985cited by this paper
• Elimination of graft-versus-host disease by in-vitro depletion of alloreactive lymphocytes with a monoclonal rat anti-human lymphocyte antibody (CAMPATH-1).

  1984influential reference
• Depletion of T lymphocytes in donor marrow prevents significant graft-versus-host disease in matched allogeneic leukaemic marrow transplant recipients.

  1984influential reference

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