Polycaprolactone/hydroxyapatite composite scaffolds: preparation, characterization, and in vitro and in vivo biological responses of human primary bone cells.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of Biomedical Materials Research. Part A

• Publication date

  2010-07-01

• Fields of study

  Medicine, Materials Science

• Identifiers
  DOI 10.1002/jbm.a.32657PMID 20166220
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bioactivity and osteoblast responses of novel biomedical nanocomposites of bioactive glass nanofiber filled poly(lactic acid).

  2008cited by this paper
• The degradation profile of novel, bioresorbable PCL-TCP scaffolds: an in vitro and in vivo study.

  2008cited by this paper
• Biodegradable polycaprolactone scaffold with controlled porosity obtained by modified particle-leaching technique

  2008cited by this paper
• Osteoblastic phenotype expression of MC3T3-E1 cultured on electrospun polycaprolactone fiber mats filled with hydroxyapatite nanoparticles.

  2007cited by this paper
• Novel bone scaffolds of electrospun polycaprolactone fibers filled with nanoparticles.

  2006cited by this paper
• Human bone marrow stromal cells: In vitro expansion and differentiation for bone engineering.

  2006cited by this paper
• Experimental studies on hydroxyapatite powder-carboxymethyl chitin composite: injectable material for bone augmentation.

  2006cited by this paper
• Preparation and characterization of novel bone scaffolds based on electrospun polycaprolactone fibers filled with nanoparticles.

  2006cited by this paper
• Alkaline-treated poly(ε-caprolactone) films: Degradation in the presence or absence of fibroblasts

  2006cited by this paper
• Alkaline-treated poly(epsilon-caprolactone) films: degradation in the presence or absence of fibroblasts.

  2006cited by this paper
• Mechanical properties and in vitro biocompatibility of porous zein scaffolds.

  2006cited by this paper
• Human osteoblast cells: isolation, characterization, and growth on polymers for musculoskeletal tissue engineering.

  2006cited by this paper
• Mitochondrial membrane potential and reactive oxygen species content of endothelial and smooth muscle cells cultured on poly(epsilon-caprolactone) films.

  2006cited by this paper
• Poly(lactide-co-glycolide)/hydroxyapatite composite scaffolds for bone tissue engineering.

  2006cited by this paper
• Mineralization capacity of Runx2/Cbfa1-genetically engineered fibroblasts is scaffold dependent.

  2006cited by this paper
• Fabrication and structural characterization of porous biodegradable poly(dl-lactic-co-glycolic acid) scaffolds with controlled range of pore sizes

  2005cited by this paper
• ErratumErratum to ‘Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction’ [Biomaterials 26 (2005) 899–904]

  2005cited by this paper
• Three-dimensional growth of differentiating MC3T3-E1 pre-osteoblasts on porous titanium scaffolds.

  2005cited by this paper
• Mechanical and dynamic viscoelastic properties of hydroxyapatite reinforced poly(ε-caprolactone)

  2005cited by this paper
• Biodegradable HA-PLA 3-D porous scaffolds: effect of nano-sized filler content on scaffold properties.

  2005cited by this paper
• Evaluation of three-dimensional scaffolds made of blends of hydroxyapatite and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) for bone reconstruction.

  2004cited by this paper
• Crystal growth and morphology of the nano-sized hydroxyapatite powders synthesized from CaHPO4·2H2O and CaCO3 by hydrolysis method

  2004cited by this paper
• Precipitation casting of polycaprolactone for applications in tissue engineering and drug delivery.

  2004cited by this paper
• Repair of Bony Defect With Combination Biomaterials

  2004cited by this paper
• Osteoblast growth and function in porous poly epsilon -caprolactone matrices for bone repair: a preliminary study.

  2003cited by this paper
• Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel-titanium bone graft substitute.

  2003cited by this paper
• Investigation of nanocomposites based on semi-interpenetrating network of [L-poly (epsilon-caprolactone)]/[net-poly (epsilon-caprolactone)] and hydroxyapatite nanocrystals.

  2003cited by this paper
• Investigation of nanocomposites based on semi-interpenetrating network of [l-poly (ε-caprolactone)]/[net-poly (ε-caprolactone)] and hydroxyapatite nanocrystals☆

  2003cited by this paper
• Environmental Degradation of Biodegradable Polyesters: 3. Effects of Alkali Treatment on Biodegradation of Poly(ε-Caprolactone) and Poly[(R)-3-Hydroxybutyrate) Films in Controled Soil

  2003cited by this paper
• Bone augmentation osteogenesis using hydroxyapatite and beta-tricalcium phosphate blocks.

  2003cited by this paper
• Poly(epsilon-caprolactone) and poly(epsilon-caprolactone)-polyvinylpyrrolidone-iodine blends as ureteral biomaterials: characterisation of mechanical and surface properties, degradation and resistance to encrustation in vitro.

  2002cited by this paper
• Poly(ε-caprolactone) as a potential material for a temporary joint spacer

  2002cited by this paper
• Poly(ε-caprolactone) and poly(ε-caprolactone)-polyvinylpyrrolidone-iodine blends as ureteral biomaterials: characterisation of mechanical and surface properties, degradation and resistance to encrustation in vitro

  2002cited by this paper
• Poly(epsilon-caprolactone) as a potential material for a temporary joint spacer.

  2002cited by this paper
• Scaffolds in tissue engineering bone and cartilage.

  2000cited by this paper
• Porous poly(L-lactic acid)/apatite composites created by biomimetic process.

  1999cited by this paper
• Three-dimensional collagen gel culture promotes osteoblastic phenotype in bone marrow derived cells.

  1999cited by this paper
• Bone formation by three-dimensional stromal osteoblast culture in biodegradable polymer scaffolds.

  1997cited by this paper
• Adhesion, growth, and matrix production by osteoblasts on collagen substrata

  1992cited by this paper

• The Influence of Cuprorivaite Nanoparticles on the Physicomechanical and Biological Performance of 3D‐Printed Scaffold Based on Carboxymethyl Chitosan Combined With Zein for Bone Tissue Engineering

  2025cites this paper
• Synthesis, Characterization, and Osteogenic Ability of Fibrillar Polycaprolactone Scaffolds Containing Hydroxyapatite Nanoparticles

  2025cites this paper
• Effects of neutralization and functionalization on chitosan/gelatin/polyvinyl alcohol scaffolds in insulin-producing cell culture.

  2025cites this paper
• Advances in the Fabrication of Polycaprolactone-Based Composite Scaffolds for Bone Tissue Engineering: From Chemical Composition to Scaffold Architecture.

  2025cites this paper
• Advancements in osteoblast sourcing, isolation, and characterization for dental tissue regeneration: a review

  2025cites this paper
• Highly Porous 3D Nanofibrous Scaffold of Polylactic Acid/Polyethylene Glycol/Calcium Phosphate for Bone Regeneration by a Two-Step Solution Blow Spinning (SBS) Facile Route

  2024cites this paper
• Functionalization of PCL-Based Fiber Scaffolds with Different Sources of Calcium and Phosphate and Odontogenic Potential on Human Dental Pulp Cells

  2024cites this paper
• Structural, Mechanical, and In-vitro Characterization of Hydroxyapatite Loaded PLA Composites

  2024cites this paper
• In-Situ Grown Nanohydroxyapatite on Graphene Oxide Nanoscrolls for Modulated Physicochemical Properties of Poly (Caprolactone) Composites

  2024cites this paper
• Biomedical Composites of Polycaprolactone/Hydroxyapatite for Bioplotting: Comprehensive Interpretation of the Reinforcement Course

  2024cites this paper
• New Generation of Osteoinductive and Antimicrobial Polycaprolactone-Based Scaffolds in Bone Tissue Engineering: A Review

  2024cites this paper
• Evaluation of polycaprolactone scaffolds containing a crude Curcuma comosa extract for potential use as cartilage scaffolds

  2024cites this paper
• Biomimetic Scaffolds Based on Mn2+-, Mg2+-, and Sr2+-Substituted Calcium Phosphates Derived from Natural Sources and Polycaprolactone

  2024cites this paper
• 3D-bioprinted alginate-based bioink scaffolds with β-tricalcium phosphate for bone regeneration applications

  2024cites this paper
• In vivo characterization of 3D-printed polycaprolactone-hydroxyapatite scaffolds with Voronoi design to advance the concept of scaffold-guided bone regeneration

  2023cites this paper
• Exploring the versatile applications of biocomposites in the medical field

  2023cites this paper
• Use of 3D-printed polycaprolactone + hyaluronic acid-based scaffold in orthopedic practice: report of two cases

  2023cites this paper
• Advancing strategies towards the development of tissue engineering scaffolds: a review

  2023cites this paper
• Vertical and horizontal ridge augmentation using customized three-dimensionally printed polycaprolactone mesh in atrophic posterior maxillae: a case report.

  2023cites this paper
• A 3D multifunctional bi-layer scaffold to regulate stem cell behaviors and promote osteochondral regeneration.

  2023cites this paper
• A novel approach to bio-mineralization of electrospun PCL scaffolds by protein and hydroxyapatite nanoparticles; molecular dynamics simulation and in-vitro evaluation

  2023cites this paper
• 3D and 4D printing hydroxyapatite-based scaffolds for bone tissue engineering and regeneration

  2023cites this paper
• Printing tissue-engineered scaffolds made of polycaprolactone and nano-hydroxyapatite with mechanical properties appropriate for trabecular bone substitutes

  2023cites this paper
• Microstructural Characterization of PCL-HA Bone Scaffolds Based on Nonsolvent-Induced Phase Separation

  2023cites this paper
• Hydrophilic surface-modified 3D printed flexible scaffolds with high ceramic particle concentrations for immunopolarization-regulation and bone regeneration.

  2023cites this paper
• Polycaprolactone, polylactic acid, and nanohydroxyapatite scaffolds obtained by electrospinning and 3D printing for tissue engineering

  2023cites this paper
• A Tunable Calcium Phosphate Coating to Drive in vivo Osseointegration of Composite Engineered Tissues

  2023cites this paper
• Biological properties of polycaprolactone and barium titanate composite in biomedical applications

  2023cites this paper
• Physicochemical and biological properties of nanohydroxyapatite grafted with star-shaped poly(ε-caprolactone)

  2022cites this paper
• Regenerating the Dental Pulp-Scaffold Materials and Approaches.

  2022cites this paper
• 3D Bioprinted Scaffolds for Bone Tissue Engineering: State-Of-The-Art and Emerging Technologies

  2022cites this paper
• A Three-Dimensional Printed Polycaprolactone–Biphasic-Calcium-Phosphate Scaffold Combined with Adipose-Derived Stem Cells Cultured in Xenogeneic Serum-Free Media for the Treatment of Bone Defects

  2022cites this paper
• Polyurethane and polyurethane/hydroxyapatite scaffold in a three‐dimensional culture system

  2022cites this paper
• Sustained delivery of andrographolide from 3D porous scaffolds imparting anticancer activity

  2022cites this paper
• Physio-Chemical and Biological Characterization of Novel HPC (Hydroxypropylcellulose):HAP (Hydroxyapatite):PLA (Poly Lactic Acid) Electrospun Nanofibers as Implantable Material for Bone Regenerative Application

  2022cites this paper
• 3D Printed Poly(𝜀-caprolactone)/Hydroxyapatite Scaffolds for Bone Tissue Engineering: A Comparative Study on a Composite Preparation by Melt Blending or Solvent Casting Techniques and the Influence of Bioceramic Content on Scaffold Properties

  2022cites this paper
• In-vitro viability of bone scaffolds fabricated using the adaptive foam reticulation technique.

  2022cites this paper
• The Use of Newly Synthesized Composite Scaffolds for Bone Regeneration - A Review of Literature

  2022cites this paper
• Assessment of 3D-Printed Polycaprolactone, Hydroxyapatite Nanoparticles and Diacrylate Poly(ethylene glycol) Scaffolds for Bone Regeneration

  2022cites this paper
• FABRICATION AND CHARACTERIZATION OF POLYCAPROLACTONE/ ZEIN AND POLYCAPROLACTONE/ZEIN/BIOGLASS COMPOSITE SCAFFOLDS FOR BONE TISSUE ENGINEERING

  2022cites this paper
• Design of 3D printed scaffolds for bone tissue engineering: A review

  2021cites this paper
• Fabrication techniques involved in developing the composite scaffolds PCL/HA nanoparticles for bone tissue engineering applications

  2021cites this paper
• Novel Silver-Functionalized Poly(ε-Caprolactone)/Biphasic Calcium Phosphate Scaffolds Designed to Counteract Post-Surgical Infections in Orthopedic Applications

  2021cites this paper
• Comparison of CAD and Voxel-Based Modelling Methodologies for the Mechanical Simulation of Extrusion-Based 3D Printed Scaffolds

  2021cites this paper
• Characterisation of bone regeneration in 3D printed ductile PCL/PEG/hydroxyapatite scaffolds with high ceramic microparticle concentrations.

  2021cites this paper
• Effect of carbonated hydroxyapatite submicron particles size on osteoblastic differentiation.

  2021cites this paper
• Review of Hybrid Materials Based on Polyhydroxyalkanoates for Tissue Engineering Applications

  2021cites this paper
• Viscoelastic, Thermal, and Mechanical Properties of Melt-Processed Poly (ε-Caprolactone) (PCL)/Hydroxyapatite (HAP) Composites

  2021cites this paper
• Hydroxyapatite Coating of Porous Polycaprolactone to Enhance Integration of a Tissue-Engineered Total Disc Replacement Spine

  2021cites this paper
• A comprehensive study of acid and base treatment of 3D printed poly(ε-caprolactone) scaffolds to tailor surface characteristics

  2021cites this paper
• Engineered Vascularized Flaps, Composed of Polymeric Soft Tissue and Live Bone, Repair Complex Tibial Defects

  2021cites this paper
• Shape fidelity and sterility assessment of 3D printed polycaprolactone and hydroxyapatite scaffolds

  2021cites this paper
• Fabrication of Polylactic Acid/β-Tricalcium Phosphate FDM 3D Printing Fiber to Enhance Osteoblastic-Like Cell Performance

  2021cites this paper
• Mesenchymal stem cell-based nanoparticles and scaffolds in regenerative medicine.

  2021cites this paper
• Bone Regeneration Assessment of Polycaprolactone Membrane on Critical-Size Defects in Rat Calvaria

  2021cites this paper
• In Vitro Biological Evaluation of a Fabricated Polycaprolactone/Pomegranate Electrospun Scaffold for Bone Regeneration

  2021cites this paper
• Green composites in bone tissue engineering

  2021cites this paper
• Design of 3D Scaffolds for Hard Tissue Engineering: From Apatites to Silicon Mesoporous Materials

  2021cites this paper
• Characterization of Polycaprolactone Nanohydroxyapatite Composites with Tunable Degradability Suitable for Indirect Printing

  2021cites this paper
• Multi-layered polydopamine coatings for the immobilization of growth factors onto highly-interconnected and bimodal PCL/HA-based scaffolds.

  2020cites this paper
• Interfacial reinforcement in bioceramic/biopolymer composite bone scaffold: The role of coupling agent.

  2020cites this paper
• An Interleukin-4-Loaded Bi-layer 3D Printed Scaffold Promotes Osteochondral Regeneration.

  2020cites this paper
• Hierarchical Surface Texturing of Hydroxyapatite Ceramics: Influence on the Adhesive Bonding Strength of Polymeric Polycaprolactone

  2020cites this paper
• An in vitro Chondro-osteo-vascular Triphasic Model of the Osteochondral Complex

  2020cites this paper
• Development of novel 3D scaffolds using BioExtruder by varying the content of hydroxyapatite and silica in PCL matrix for bone tissue engineering

  2020cites this paper
• Process–Structure–Quality Relationships of Three-Dimensional Printed Poly(Caprolactone)-Hydroxyapatite Scaffolds

  2020cites this paper
• In vitro augmentation of chondrogenesis by Epigallocatechin gallate in primary Human chondrocytes - Sustained release model for cartilage regeneration

  2020cites this paper
• Assessment of Modified Polycaprolactone Membrane in Horizontal Ridge Augmentation of Atrophic Ridge

  2020cites this paper
• Bone tissue engineering gelatin–hydroxyapatite/graphene oxide scaffolds with the ability to release vitamin D: fabrication, characterization, and in vitro study

  2020cites this paper
• Natural and Synthetic Polymers for Bone Scaffolds Optimization

  2020cites this paper
• Melatonin delivery from PCL scaffold enhances glycosaminoglycans deposition in human chondrocytes – Bioactive scaffold model for cartilage regeneration

  2020cites this paper
• A laser-cutting-based manufacturing process for the generation of three-dimensional scaffolds for tissue engineering using Polycaprolactone/Hydroxyapatite composite polymer

  2019cites this paper
• Developing a synthetic composite membrane for cleft palate repair

  2019cites this paper
• Syntheses of biodegradable polymer networks based on polycaprolactone and glutamic acid

  2019cites this paper
• Characterization of biomimetic silicate- and strontium-containing hydroxyapatite microparticles embedded in biodegradable electrospun polycaprolactone scaffolds for bone regeneration

  2019cites this paper
• Poly (sodium 4-styrene sulfonate)-modified hydroxyapatite nanoparticles in zein-based scaffold as a drug carrier for vancomycin.

  2019cites this paper
• Polymer Nanocomposites Based on Poly(ε-caprolactone), Hydroxyapatite and Graphene Oxide

  2019cites this paper
• Advanced biomaterials for repairing and reconstruction of mandibular defects.

  2019cites this paper
• Taguchi's methods to optimize the properties and bioactivity of 3D printed polycaprolactone/mineral trioxide aggregate scaffold: Theoretical predictions and experimental validation.

  2019cites this paper
• In vitro and in vivo evaluation of rotary-jet-spun poly(ɛ-caprolactone) with high loading of nano-hydroxyapatite

  2019cites this paper
• The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect

  2019cites this paper
• Development macro-porous electro-spun meshes with clinically relevant mechanical properties—a technical note

  2019cites this paper
• Hybrid Composite Biomaterials

  2019cites this paper
• "Tree to Bone": Lignin-Polycaprolactone Nanofibers for Hydroxyapatite Biomineralization.

  2019cites this paper
• Biodegradable polymer nanocomposites for tissue engineering: synthetic strategies and related applications

  2019cites this paper
• Three-dimensional printed polycaprolactone-microcrystalline cellulose scaffolds.

  2019cites this paper
• Characterization of a bioactive Jagged1-coated polycaprolactone-based membrane for guided tissue regeneration.

  2018cites this paper
• Hydroxyapatite-polymer biocomposites for bone regeneration: A review of current trends.

  2018cites this paper
• Polycaprolactone–carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusion

  2018cites this paper
• Comparison of isolation techniques for bone marrow derived canine mesenchymal stem cells (MSCs) and the compatibility of MSCs loaded onto polycarpolactone hydroxyapatite

  2018cites this paper
• Fabrication and evaluation of 3D printed BCP scaffolds reinforced with ZrO2 for bone tissue applications

  2018cites this paper
• Hybrid PCL/CaCO3 scaffolds with capabilities of carrying biologically active molecules: Synthesis, loading and in vivo applications.

  2018cites this paper
• Comparison of three-dimensional printing for fabricating silk fibroin-blended scaffolds

  2018cites this paper
• Fabrication and Properties of Polycaprolactone Composites Containing Calcium Phosphate-Based Ceramics and Bioactive Glasses in Bone Tissue Engineering: A Review

  2018influential citation
• Polycaprolactone–carboxymethyl cellulose composites for manufacturing porous scaffolds by material extrusion

  2018cites this paper
• Biocomposites and Hybrid Biomaterials of Calcium Orthophosphates (CaPO4) with Polymers

  2018cites this paper
• Porous Polycaprolactone Scaffold Engineered with Naringin Loaded Bovine Serum Albumin Nanoparticles for Bone Tissue Engineering

  2018cites this paper
• 3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: high-resolution tomography and in vitro study

  2018cites this paper
• Synergistic Effects of Beta Tri-Calcium Phosphate and Porcine-Derived Decellularized Bone Extracellular Matrix in 3D-Printed Polycaprolactone Scaffold on Bone Regeneration.

  2018cites this paper
• Effect of different mineralization processes on in vitro and in vivo bone regeneration and osteoblast-macrophage cross-talk in co-culture system using dual growth factor mediated non-mulberry silk fibroin grafted poly (Є-caprolactone) nanofibrous scaffold.

  2017cites this paper